A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Pontikos, Nikolas ^a   Smyth, Deborah J ^a   Schuilenburg, Helen ^a   Howson, Joanna M M ^a,b   Walker, Neil M ^a   Burren, Oliver S ^a   Guo, Hui ^a   Onengut Gumuscu, Suna ^c   Chen, Wei Min ^c   Concannon, Patrick ^d   Rich, Stephen S ^c   Jayaraman, Jyothi ^a,e   Jiang, Wei ^a,e   Traherne, James A ^a,e   Trowsdale, John ^a,e   Todd, John A ^a   Wallace, Chris ^a,f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f MRC BIOSTATISTICS UNIT   (United Kingdom)

Author keywords

CNV; HLA Bw4; ImmunoChip; Imputation; KIR; KIR2DL3; KIR2DL5; KIR2DS1; KIR2DS4; KIR2DS5; KIR3DL1; KIR3DS1; qPCR; T1D

Indexed keywords

DNA; HLA B ANTIGEN; HLA BW4 ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; GENE; GENE CLUSTER; GENE DOSAGE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIR GENE; KIR2DS4 GENE; KIR3DL1 GENE; KIR3DL3 GENE; KIR3DL5 GENE; KIR3DS1 GENE; KIR3DS5 GENE; MAJOR CLINICAL STUDY; NOISE; POLYMERASE CHAIN REACTION; PROTEIN BINDING; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 1; GENE DOSAGE; GENETIC PREDISPOSITION TO DISEASE; HLA-A ANTIGENS; HLA-B ANTIGENS; HUMANS; MULTIPLEX POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, KIR; RECEPTORS, KIR3DL1; RECEPTORS, KIR3DS1;

EID: 84899479629     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-274     Document Type: Article

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