Novel PET probes 18F-BCPP-EF and 18F-BCPP-BF for mitochondrial complex I: A PET study in comparison with 18F-BMS- 747158-02 in rat brain

Journal of Nuclear Medicine

Volumn 55, Issue 3, 2014, Pages 473-480

  Tsukada, Hideo ^a   Nishiyama, Shingo ^a   Fukumoto, Dai ^a   Kanazawa, Masakatsu ^a   Harada, Norihiro ^a  

^a CENTRAL RESEARCH LABORATORY   (Japan)

Author keywords

Brain; Ischemia; Mitochondria complex I; PET

Indexed keywords

2 TERT BUTYL 4 CHLORO 5 [6 (4 FLUOROBUTOXY) PYRIDIN 3 YLMETHOXY] 2H PYRIDAZIN 3 ONE F 18; 2 TERT BUTYL 4 CHLORO 5 [6 [2 (2 FLUOROETHOXY) ETHOXY] PYRIDIN 3 YLMETHOXY] 2H PYRIDAZIN 3 ONE F 18; FLURPIRIDAZ F 18; RADIOPHARMACEUTICAL AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; UNCLASSIFIED DRUG; 2-TERT-BUTYL-4-CHLORO-5-(6-(2-(2-FLUOROETHOXY)ETHOXY)PYRIDIN-3-YLMETHOXY)-2H-PYRIDAZIN-3-ONE; 2-TERT-BUTYL-4-CHLORO-5-(6-(4-FLUOROBUTOXY)PYRIDIN-3-YLMETHOXY)-2H-PYRIDAZIN-3-ONE; 2 TERT BUTYL 4 CHLORO 5 (6 (2 (2 FLUOROETHOXY)ETHOXY)PYRIDIN 3 YLMETHOXY) 2H PYRIDAZIN 3 ONE; 2 TERT BUTYL 4 CHLORO 5 (6 (4 FLUOROBUTOXY)PYRIDIN 3 YLMETHOXY) 2H PYRIDAZIN 3 ONE; DIAGNOSTIC AGENT; PYRIDAZINE; PYRIDAZINE DERIVATIVE; PYRIDINE DERIVATIVE;

AFFINITY LABELING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; ENZYME ACTIVITY; HEART; HEART MUSCLE CELL; IN VITRO STUDY; LIGAND BINDING; MALE; MUSCLE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOACTIVITY; RAT; TISSUE DISTRIBUTION; 18F-BCPP-EF; ANIMAL; BRAIN; CATTLE; COMPARATIVE STUDY; ISCHEMIA; METABOLISM; MITOCHONDRIA COMPLEX I; PET; SCINTISCANNING; SPRAGUE DAWLEY RAT;

18F-BCPP-EF; BRAIN; ISCHEMIA; MITOCHONDRIA COMPLEX I; PET;

ANIMALS; BRAIN; CATTLE; ELECTRON TRANSPORT COMPLEX I; MALE; POSITRON-EMISSION TOMOGRAPHY; PYRIDAZINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84899474618     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.125328     Document Type: Article

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