Effect of probiotic (VSL#3) and omega-3 on lipid profile, insulin sensitivity, inflammatory markers, and gut colonization in overweight adults: A randomized, controlled trial

Mediators of Inflammation

Volumn 2014, Issue , 2014, Pages

  Rajkumar, Hemalatha ^a   Mahmood, Naseha ^a   Kumar, Manoj ^a   Varikuti, Sudarshan Reddy ^a   Challa, Hanumanth Reddy ^a   Myakala, Shiva Prakash ^a  

^a NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OMEGA 3 FATTY ACID; PLACEBO; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN; VSL3; CHOLESTEROL; LIPID; PROBIOTIC AGENT;

ADULT; ARTICLE; BACTERIAL VIABILITY; BIFIDOBACTERIUM BREVE; BIFIDOBACTERIUM LONGUM; BIFIDOBACTERIUM LONGUM INFANTIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FECES MICROFLORA; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTESTINE FLORA; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS BULGARICUS; LACTOBACILLUS PARACASEI; LACTOBACILLUS PLANTARUM; LIPID BLOOD LEVEL; LIPID COMPOSITION; MAJOR CLINICAL STUDY; MALE; MICROBIAL COLONIZATION; NONHUMAN; OBESITY; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; STREPTOCOCCUS THERMOPHILUS; BLOOD; GASTROINTESTINAL TRACT; MICROBIOLOGY; MIDDLE AGED; PHYSIOLOGY;

ADULT; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; FATTY ACIDS, OMEGA-3; FEMALE; GASTROINTESTINAL TRACT; HUMANS; INFLAMMATION; INSULIN RESISTANCE; LIPIDS; MALE; MIDDLE AGED; OVERWEIGHT; PROBIOTICS; TRIGLYCERIDES;

EID: 84899460663     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/348959     Document Type: Article

References (42)

1. Ridker P. M., Hennekens C. H., Buring J. E., Rifai N., C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. The New England Journal of Medicine 2000 342 12 836 843 2-s2.0-0034704893 10.1056/NEJM200003233421202 (Pubitemid 30165206)
2. Blake G. J., Ridker P. M., Novel clinical markers of vascular wall inflammation. Circulation Research 2001 89 9 763 771 2-s2.0-0035955760 (Pubitemid 34633846)
3. Faloia E., Michetti G., de Robertis M., Luconi M. P., Furlani G., Boscaro M., Inflammation as a link between obesity and metabolic syndrome. Journal of Nutrition and Metabolism 2012 2012 7 476380 10.1155/2012/476380
4. WHO, Obesity and overweight. Fact Sheet N°311 2013 Geneva, Switzerland WHO. http://www.who.int/mediacentre/factsheets/fs311/en
5. Bhalwar R., Text Book of Public Health and Community Medicine 2009 1st Pune, India Department of Community Medicine, AFMC
6. Koenig W., Sund M., Fröhlich M., Fischer H.-G., Löwel H., Döring A., Hutchinson W. L., Pepys M. B., C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (monitoring trends and determinants in cardiovascular disease) Augsburg cohort study, 1984 to 1992. Circulation 1999 99 2 237 242 2-s2.0-0032923669 (Pubitemid 29056365)
7. Pepys M. B., Rowe I. F., Baltz M. L., C-Reactive protein: binding to lipids and lipoproteins. International Review of Experimental Pathology 1985 27 83 111 2-s2.0-0021890196 (Pubitemid 15060290)
8. Rohde L. E. P., Hennekens C. H., Ridker P. M., Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men. American Journal of Cardiology 1999 84 9 1018 1022 2-s2.0-0032720533 10.1016/S0002- 9149(99)00491-9 (Pubitemid 29505368)
9. Hotamisligil G. S., Arner P., Caro J. F., Atkinson R. L., Spiegelman B. M., Increased adipose tissue expression of tumor necrosis factor- in human obesity and insulin resistance. Journal of Clinical Investigation 1995 95 5 2409 2415 2-s2.0-0028931724
10. Purohit A., Ghilchik M. W., Duncan L., Wang D. Y., Singh A., Walker M. M., Reed M. J., Aromatase activity and interleukin-6 production by normal and malignant breast tissues. Journal of Clinical Endocrinology and Metabolism 1995 80 10 3052 3058 2-s2.0-0028787970
11. Baumann H., Gauldie J., The acute phase response. Immunology Today 1994 15 2 74 80 2-s2.0-0028095919 10.1016/0167-5699(94)90137-6 (Pubitemid 24049800)
12. Papanicolaou D. A., Wilder R. L., Manolagas S. C., Chrousos G. P., The pathophysiologic roles of interleukin-6 in human disease. Annals of Internal Medicine 1998 128 2 127 137 2-s2.0-0031963046 (Pubitemid 28053135)
13. Yudkin J. S., Stehouwer C. D. A., Emeis J. J., Coppack S. W., C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 4 972 978 2-s2.0-0032943709 (Pubitemid 29177345)
14. Jones M. L., Martoni C. J., Parent M., Prakash S., Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic adults. British Journal of Nutrition 2012 107 10 1505 1513 10.1017/S0007114511004703
15. Kumar M., Rakesh S., Nagpal R., Probiotic Lactobacillus rhamnosus GG and Aloe vera gel improve lipid profiles in hypercholesterolemic rats. Nutrition 2013 29 3 574 579 10.1016/j.nut.2012.09.006
16. Li Z., Yang S., Lin H., Huang J., Watkins P. A., Moser A. B., DeSimone C., Song X.-Y., Diehl A. M., Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 2003 37 2 343 350 2-s2.0-0037309589 10.1053/jhep.2003.50048 (Pubitemid 36152533)
17. Tai C. C., Ding S. T., N-3 polyunsaturated fatty acids regulate lipid metabolism through several inflammation mediators: mechanisms and implications for obesity prevention. Journal of Nutritional Biochemistry 2010 21 5 357 363 2-s2.0-77951498306 10.1016/j.jnutbio.2009.09.010
18. Root Martin, Collier S. R., Zwetsloot K. A., West K. L., McGinn M. C., A randomized trial of fish oil omega-3 fatty acids on arterial health, inflammation, and metabolic syndrome in a young healthy population. Nutrition Journal 2013 12, article 1 10.1186/1475-2891-12-1
19. Adkins Y., Kelley D. S., Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids. Journal of Nutritional Biochemistry 2010 21 9 781 792 2-s2.0-77955842717 10.1016/j.jnutbio.2009.12.004
20. Bays H. E., Tighe A. P., Sadovsky R., Davidson M. H., Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications. Expert Review of Cardiovascular Therapy 2008 6 3 391 409 2-s2.0-41449110020 10.1586/14779072.6.3.391
21. Friedewald W. T., Levy R. I., Fredrickson D. S., Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry 1972 18 6 499 502 2-s2.0-0015348189
22. Matthews D. R., Hosker J. P., Rudenski A. S., Homeostasis model assessment: insulin resistance and β -cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 7 412 419 2-s2.0-0021813187 (Pubitemid 15018832)
23. Anderson J. W., Gilliland S. E., Effect of fermented milk (yogurt) containing Lactobacillus acidophilus L1 on serum cholesterol in hypercholesterolemic humans. Journal of the American College of Nutrition 1999 18 1 43 50 2-s2.0-0033024518 (Pubitemid 29088685)
24. Xiao J. Z., Kondo S., Takahashi N., Miyaji K., Oshida K., Hiramatsu A., Iwatsuki K., Kokubo S., Hosono A., Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers. Journal of Dairy Science 2003 86 7 2452 2461 2-s2.0-0141609047 (Pubitemid 39001266)
25. Kießling G., Schneider J., Jahreis G., Long-term consumption of fermented dairy products over 6 months increases HDL cholesterol. European Journal of Clinical Nutrition 2002 56 9 843 849 2-s2.0-0036739647 10.1038/sj.ejcn.1601399
26. Bukowska H., Pieczul-Mroz J., Jastrzebska M., Chelstowski K., Naruszewicz M., Decrease in fibrinogen and LDL-cholesterol levels upon supplementation of diet with Lactobacillus plantarum in subjects with moderately elevated cholesterol. Atherosclerosis 1998 137 2 437 438 2-s2.0-0031976890 10.1016/S0021-9150(97)00283-9 (Pubitemid 28215890)
27. Naruszewicz M., Johansson M.-L., Zapolska-Downar D., Bukowska H., Effect of Lactobacillus plantarum 299v on cardiovascular disease risk factors in smokers. American Journal of Clinical Nutrition 2002 76 6 1249 1255 2-s2.0-18744378321 (Pubitemid 35416559)
28. Hatakka K., Mutanen M., Holma R., Saxelin M., Korpela R., Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp shermanii JS administered in capsules is ineffective in lowering serum lipids. Journal of the American College of Nutrition 2008 27 4 441 447 10.1080/07315724.2008.10719723 2-s2.0-58749100326
29. Simons L. A., Amansec S. G., Conway P., Effect of Lactobacillus fermentum on serum lipids in subjects with elevated serum cholesterol. Nutrition, Metabolism and Cardiovascular Diseases 2006 16 8 531 535 2-s2.0-33751189183 10.1016/j.numecd.2005.10.009 (Pubitemid 44780082)
30. Lewis S. J., Burmeister S., A double-blind placebo-controlled study of the effects of Lactobacillus acidophilus on plasma lipids. European Journal of Clinical Nutrition 2005 59 6 776 780 2-s2.0-21244483147 10.1038/sj.ejcn.1602139 (Pubitemid 40894942)
31. Kumar R., Rajkumar H., Kumar M., Varikuti S. R., Athimamula R., Shujauddin M., Ramagoni R., Kondapalli N., Molecular cloning, characterization and heterologous expression of bile salt hydrolase (Bsh) from Lactobacillus fermentum NCDO394. Molecular Biology Reports 2013 40 8 5057 5066 10.1007/s11033-013-2607-2
32. Kumar M., Nagpal R., Kumar R., Hemalatha R., Verma V., Kumar A., Chakraborty C., Singh B., Marotta F., Jain S., Yadav H., Cholesterol lowering probiotics as potential biotherapeutics for metabolic diseases. Experimental Diabetes Research 2012 2012 14 902917 10.1155/2012/902917
33. Nordgaard I., Mortensen P. B., Langkilde A. M., Small intestinal malabsorption and colonic fermentation of resistant starch and resistant peptides to short-chain fatty acids. Nutrition 1995 11 2 129 137 2-s2.0-0028908638
34. Venter C. S., Vorster H. H., Possible metabolic consequences of fermentation in the colon for humans. Medical Hypotheses 1989 29 3 161 166 2-s2.0-0024359740 (Pubitemid 19186351)
35. Phillipson B. E., Rothrock D. W., Connor W. E., Reduction of plasma lipids, lipoproteins, and apoproteins by dietary fish oils in patients with hypertriglyceridemia. The New England Journal of Medicine 1985 312 19 1210 1216 2-s2.0-0021821575 (Pubitemid 15009154)
36. Harris W. S., Connor W. E., Illingworth D. R., Rothrock D. W., Foster D. M., Effects of fish oil on VLDL triglyceride kinetics in humans. Journal of Lipid Research 1990 31 9 1549 1558 2-s2.0-0025150912 (Pubitemid 20321716)
37. Nestel P. J., Connor W. E., Reardon M. F., Suppression by diets rich in fish oil of very low density lipoprotein production in man. Journal of Clinical Investigation 1984 74 1 82 89 2-s2.0-0021278243 (Pubitemid 14086047)
38. Ejtahed H. S., Mohtadi-Nia J., Homayouni-Rad A., Niafar M., Asghari-Jafarabadi M., Mofid V., Probiotic yogurt improves antioxidant status in type 2 diabetic patients. Nutrition 2012 28 5 539 543 2-s2.0-84859214519 10.1016/j.nut.2011.08.013
39. Matsuzaki T., Yamazaki R., Hashimoto S., Yokokura T., Antidiabetic effects of an oral administration of Lactobacillus casei in a non-insulin-dependent diabetes mellitus (NIDDM) model using KK-A(y) mice. Endocrine Journal 1997 44 3 357 365 2-s2.0-0030792512 (Pubitemid 27310421)
40. Visser M., Bouter L. M., McQuillan G. M., Wener M. H., Harris T. B., Elevated C-reactive protein levels in overweight and obese adults. Journal of the American Medical Association 1999 282 22 2131 2135 2-s2.0-0033537013 10.1001/jama.282.22.2131
41. Cani P. D., Delzenne N. M., Amar J., Burcelin R., Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding. Pathologie Biologie 2008 56 5 305 309 2-s2.0-47249096253 10.1016/j.patbio.2007.09.008
42. Tilg H., Kaser A., Gut microbiome, obesity, and metabolic dysfunction. Journal of Clinical Investigation 2011 121 6 2126 2132 2-s2.0-79957902145 10.1172/JCI58109