A comparative study of gelatin sponge scaffolds and PLGA scaffolds transplanted to completely transected spinal cord of rat

Journal of Biomedical Materials Research - Part A

Volumn 102, Issue 6, 2014, Pages 1715-1725

  Du, Bao Ling ^a   Zeng, Chen Guang ^b   Zhang, Wei ^a   Quan, Da Ping ^b   Ling, Eng Ang ^c   Zeng, Yuan Shan ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

acid sensing ion channel 1a; gelatin sponge scaffold; neuron survival; PLGA scaffold; spinal cord injury

Indexed keywords

CELLS; COPOLYMERS; CYTOLOGY; NEURONS; PATIENT REHABILITATION;

ACID-SENSING ION CHANNELS; ADENOMATOUS POLYPOSIS COLI; GELATIN SPONGE; INJURED SPINAL CORDS; MICROTUBULE ASSOCIATED PROTEIN; PLGA SCAFFOLDS; POLY(LACTIC-CO-GLYCOLIC ACID); SPINAL CORD INJURIES (SCI);

SCAFFOLDS (BIOLOGY);

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; CD68 ANTIGEN; GELATIN SPONGE; GELATIN SPONGE SCAFFOLD; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; POLYGLACTIN; TISSUE SCAFFOLD; UNCLASSIFIED DRUG; ASIC1 PROTEIN, RAT; GELATIN; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ACIDITY; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL COUNTING; CELL SURVIVAL; COLON POLYPOSIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GLIA; LUMBAR SPINE; MESENCEPHALON; MYELITIS; NERVE FIBER; NERVE REGENERATION; NEUROFILAMENT; NISSL STAINING; NONHUMAN; PROTEIN EXPRESSION; RAT; RED NUCLEUS; SENSORIMOTOR CORTEX; SPINAL CORD TRANSSECTION; STAINING; TRANSPLANTATION; WESTERN BLOTTING; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; NERVE CELL; PATHOLOGY; SPINAL CORD; SPINAL CORD INJURIES; SPRAGUE DAWLEY RAT; SURGERY; TISSUE SCAFFOLD;

ACID SENSING ION CHANNELS; ANIMALS; CELL SURVIVAL; FEMALE; GELATIN; LACTIC ACID; NEURONS; POLYGLYCOLIC ACID; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL CORD INJURIES; TISSUE SCAFFOLDS;

EID: 84899443845     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34835     Document Type: Article

References (41)

1. Friedman JA, Windebank AJ, Moore MJ, Spinner RJ, Currier BL, Yaszemski MJ,. Biodegradable polymer grafts for surgicalrepair of the injured spinal cord. Neurosurgery 2002; 51: 742-751.
2. Lee SY, Oh JH, Kim JC, Kim YH, Kim SH, Choi JW,. In vivo conjunctival reconstruction using modified PLGA grafts for decreased scar formation and contraction. Biomaterials 2003; 24: 5049-5059.
3. Oudega M, Gautier SE, Chapon P, Fragoso M, Bates ML, Parel JM, Bunge MB,. Axonal regeneration into Schwann cell grafts within resorbable poly (alpha-hydroxyacid) guidance channels in the adult rat spinal cord. Biomaterials 2001; 22: 1125-1136.
4. Teng YD, Lavik EB, Qu X, Park KI, Ourednik J, Zurakowski D, Langer R, Snyder EY,. Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci U S A 2002; 99: 3024-3029.
5. Xu XM, Zhang SX, Li H, Aebischer P, Bunge MB,. Regrowth of axons into the distal spinal cord through a Schwann-cell-seededmini-channel implanted into hemisected adult rat spinal cord. Eur J Neurosci 1999; 11: 1723-1740.
6. Kim BS, Mooney DJ,. Development of biocompatible synthetic extracellular matrices for tissue engineering. Trends Biotechnol 1998; 16: 224-230.
7. Patist CM, Mulder MB, Gautier SE, Maquet V, Je'rome R, Oudega M,. Freezedried poly(d,l -lactic acid) macroporous guidance scaffolds impregnated with brain-derived neurotrophic factor in the transected adult rat thoracic spinal cord. Biomaterials 2004; 25: 1569-1582.
8. Hurtado A, Moon LD, Maquet V, Blits B, Je'rome R, Oudega M,. Poly (d,l -lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord. Biomaterials 2006; 27: 430-442.
9. Moore MJ, Friedman JA, Lewellyn EB, Mantila SM, Krych AJ, Ameenuddin S, Knight AM, Lu L, Currier BL, Spinner RJ, Marsh RW, Windebank AJ, Yaszemski MJ,. Multiple-channel scaffolds to promote spinal cord axon regeneration. Biomaterials 2006; 27: 419-429.
10. Xiong Y, Zeng YS, Zeng CG, Du BL, He LM, Quan DP, Zhang W, Wang JM, Wu JL, Li Y, Li J,. Synaptic transmission of neural stem cells seeded in 3-dimensional PLGA scaffolds. Biomaterials 2009; 30: 3711-3722.
11. Du BL, Xiong Y, Zeng CG, He LM, Zhang W, Quan DP, Wu JL, Li Y, Zeng YS,. Transplantation of artificial neural construct partly improved spinal tissue repair and functional recovery in rats with spinal cord transection. Brain Res 2011; 1400: 87-98.
12. He L, Zhang Y, Zeng C, Ngiam M, Liao S, Quan D, Zeng Y, Lu J, Ramakrishna S,. Manufacture of PLGA multiple-channel conduits with precise hierarchical pore architectures and in vitro/vivo evaluation for spinal cord injury. Tissue Eng 2009; 15: 243-255.
13. Pearlman AL, Sheppard AM,. Extracellular matrix in early cortical development. Prog. Brain Res 1996; 108: 117-134.
14. Yoshii S, Oka M, Shima M, Akagi Ml, Taniguchi A,. Bridging a spinal cord defect using collagen filament. Spine 2003; 28: 2346-2351.
15. Harley BA, Spilker MH, Wu JW, Asano K, Hsu HP, Spector M, Yannas IV,. Optimal degradation rate for collagen chambers used for regeneration of peripheral nerves over long gaps. Cells Tissues Organs 2004; 176: 153-165.
16. Midha R, Munro CA, Dalton PD, Tator CH, Shoichet MS,. Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube. J Neurosurg 2003; 99: 555-565.
17. Paino CL, Bunge MB,. Induction of axon growth into Schwann cell implants grafted into lesioned adult rat spinal cord. Exp Neurol 1991; 114: 254-257.
18. Zeng X, Zeng YS, Ma YH, Lu LY, Du BL, Zhang W, Li Y, Chan WY,. Bone marrow mesenchymal stem cells in a three dimensional gelatin sponge scaffold attenuate inflammation, promote angiogenesis and reduce cavity formation in experimental spinal cord injury. Cell Transplant 2011; 20: 1881-1899.
19. Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M,. A proton-gated cation channel involved in acid-sensing. Nature 1997; 386: 173-177.
20. Lingueglia E,. Acid-sensing ion channels in sensory perception. J Biol Chem 2007; 282: 17325-17329.
21. Wemmie JA, Price MP, Welsh MJ,. Acid-sensing ion channels: Advances, questions and therapeutic opportunities. Trends Neurosci 2006; 29: 578-586.
22. Vukicevic M, Kellenberger S,. Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons. Am J Physiol Cell Physiol 2004; 287: C682-C690.
23. Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, MacDonald JF, Wemmie JA, Price MP, Welsh MJ, Simon RP,. Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels. Cell 2004; 118: 687-698.
24. Gao J, Duan B, Wang DG, Deng XH, Zhang GY, Xu L, Xu TL,. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 2005; 48: 635-646.
25. Friese MA, Craner MJ, Etzensperger R, Vergo S, Wemmie JA, Welsh MJ, Vincent A, Fugger L,. Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat Med 2007; 13: 1483-1489.
26. Arias RL, Sung ML, Vasylyev D, Zhang MY, Albinson K, Kubek K, Kagan N, Beyer C, Lin Q, Dwyer JM, Zaleska MM, Bowlby MR, Dunlop J, Monaghan M,. Amiloride is neuroprotective in an MPTP model of Parkinson's disease. Neurobiol Dis 2008; 31: 334-341.
27. Wong HK, Bauer P.O, Kurosawa M, Goswami A, Washizu C, Machida Y, Tosaki A, Yamada M, Knöpfel T, Nakamura T, Nukina N,. Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism. Hum Mol Genet 2008; 17: 3223-3235.
28. Ziemann AE, Schnizler MK, Albert GW, Severson MA, Howard MA 3rd, Welsh MJ, Wemmie JA,. Seizure termination by acidosis depends on ASIC1a. Nat Neurosci 2008; 11: 816-822.
29. Sun X, Cao YB, Hu LF, Yang YP, Li J, Wang F, Liu CF,. ASICs mediate themodulatory effect by paeoniflorin on alpha-synuclein autophagic degradation. Brain Res 2011; 1396: 77-87.
30. Pignataro G, Cuomo O, Esposito E, Sirabella R, Di Renzo G, Annunziato L,. ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning. Int J Physiol Pathophysiol Pharmacol 2011; 3: 1-8.
31. Yi-Zhi Wang, Tian-Le Xu,. Acidosis, acid-sensing ion channels, and neuronal cell death. Mol Neurobiol 2011; 44: 350-358.
32. Sutherland SP, Cook SP, MeCleskey EW,. Chemical mediators of Pain due to tissue damage and ischemia. Prog Brain Res 2000; 129: 21-38.
33. Wu LJ, Duan B, Mei YD, Gao J, Chen JG, Zhuo M, Xu L, Wu M, Xu TL,. Characterization of acid-sensing ion channels in dorsal homneurons of rat spinal cord. J Biol Chem 2004; 279: 43716-43724.
34. Sugiura T, Dang K, Lamb K, Bielefeldt K, Gebhart GF,. Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach. J Neurosci 2005; 25: 2617-2627.
35. Voilley N, de Weille J, Mamet J, Lazdunski M,. Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors. J Neurosci 2001; 21: 8026-8033.
36. Weng XC, Zheng JQ, Jin QE, Ma XY,. Inhibition of acid-induced apoptosis by targeting ASIC1a mRNA with short hairpin RNA. Acta Pharmacol Sin 2007; 28: 1621-1627.
37. Yiu G, He Z,. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci 2006; 7: 617-627.
38. Silver J, Miller JH,. Regeneration beyond the glial scar. Nat Rev Neurosci 2004; 5: 146-156.
39. Uchida K, Baba H, Maezawa Y, Kubota C,. Progressive changes in neurofilament proteins and growth-associated protein-43 immunoreactivities at the site of cervical spinal cord compression in spinal hyperostotic mice. Spine 2002; 27: 480-486.
40. Yabe JT, Wang FS, Chylinski T, Katchmar T, Shea TB,. Selective ccumulation of the high molecular weight neurofilament subunit within the distal region of growing axonal neuritis. Cell Motil Cytoskeleton 2001; 50: 1-12.
41. Weis J, Schroder JM,. The influence of fat tissue on neuroma formation. J Neurosurg 1989; 71: 588-593.