Human umbilical cord-derived mesenchymal stem cells can secrete insulin in vitro and in vivo

Biotechnology and Applied Biochemistry

Volumn 61, Issue 2, 2014, Pages 82-92

  Niki Boroujeni, Zahra ^a   Aleyasin, Ahmad ^a  

^a NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

Author keywords

diabetes mellitus; hUDSCs; insulin producing cells; nonintegrated lentiviruses; PDX1

Indexed keywords

FLOWCHARTING; GLUCOSE; INSULIN; PROTEINS; STEM CELLS;

DIABETES MELLITUS; HUDSCS; INSULIN-PRODUCING CELLS; NONINTEGRATED LENTIVIRUSES; PDX1;

CELL CULTURE;

GLUCAGON; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; LENTIVIRUS VECTOR; NEUROGENIN 3; SOMATOSTATIN; TRANSCRIPTION FACTOR PDX 1; HOMEODOMAIN PROTEIN; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CORD BLOOD STEM CELL TRANSPLANTATION; DIABETES MELLITUS; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN UMBILICAL CORD DERIVED STEM CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MESENCHYMAL STEM CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CYTOLOGY; DIABETES MELLITUS, TYPE 1; GENE THERAPY; GENETICS; LENTIVIRINAE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; PANCREAS ISLET BETA CELL; RAT; SECRETION (PROCESS); UMBILICAL CORD;

LENTIVIRUS; RATTUS;

ANIMALS; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; FLOW CYTOMETRY; GENETIC THERAPY; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; LENTIVIRUS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; RATS; TRANS-ACTIVATORS; UMBILICAL CORD;

EID: 84899437199     PISSN: 08854513     EISSN: 14708744     Source Type: Journal    
DOI: 10.1002/bab.1127     Document Type: Article

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