The cyclic AMP response element-binding protein (CREB) mediates smooth muscle cell proliferation in response to angiotensin II

Journal of Cell Communication and Signaling

Volumn 8, Issue 1, 2014, Pages 29-37

  Molnar, Peter ^a,b   Perrault, Raissa ^a,b   Louis, Sherif ^a,b   Zahradka, Peter ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b ST BONIFACE GENERAL HOSPITAL   (Canada)

Author keywords

Angiotensin II; CREB; Neointimal hyperplasia; Proliferation; Smooth muscle

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ANGIOPLASTY; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL HYPERPLASIA; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; EX VIVO STUDY; IMMUNOFLUORESCENCE; MITOGENESIS; NEOINTIMA; NONHUMAN; PORCINE MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ADENOVIRIDAE; SUS;

EID: 84899418566     PISSN: 18739601     EISSN: 1873961X     Source Type: Journal    
DOI: 10.1007/s12079-013-0215-5     Document Type: Article

References (41)

1. Arthur JS, Cohen P (2000)MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells. FEBS Lett 482:44-48
2. Cheng HC, Kemp BE, Pearson RB, Smith AJ, Misconi L, Van Patten SM, Walsh DA (1986) A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J Biol Chem 261:989-992 (Pubitemid 16144753)
3. Chijiwa T, Mishima A, Hagiwara M, SanoM, Hayashi K, Inoue T, Naito K, Toshioka T, Hidaka H (1990) Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclicAMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5- isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 265:5267-5272
4. Deak M, Clifton AD, Lucocq LM, Alessi DR (1998) Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J 17:4426-4441 (Pubitemid 28362632)
5. Eguchi S, Dempsey PJ, Frank GD, Motley ED, Inagami T (2001) Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease- dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK. J Biol Chem 276:7957-7962
6. Funakoshi Y, Ichiki T, Takeda K, Tokuno T, Iino N, Takeshita A (2002) Critical role of cAMP-response element-binding protein for angiotensin II-induced hypertrophy of vascular smooth muscle cells. J Biol Chem 277:18710-18717 (Pubitemid 34952428)
7. Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M (2001) CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413:179-183 (Pubitemid 32867880)
8. Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, Eguchi S (2007) Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology. Clin Sci (Lond) 112:417-428 (Pubitemid 46587457)
9. Ichiki T (2006) Role of cAMP response element binding protein in cardiovascular remodeling: good, bad, or both? Arterioscler Thromb Vasc Biol 26:449-455
10. Kase H, Iwahashi K, Nakanishi S, Matsuda Y, Yamada K, Takahashi M, Murakata C, Sato A, Kaneko M (1987) K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun 142:436-440 (Pubitemid 17003365)
11. Khan P, Drobic B, Perez-Cadahia B, Healy S, He S, Davie JR (2013) Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction. PLoS One 8:e63189
12. Klemm DJ, Watson PA, Frid MG, Dempsey EC, Schaack J, Colton LA, Nesterova A, Stenmark KR, Reusch JE (2001) cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J Biol Chem 276:46132-46141
13. Lochner A, Moolman JA (2006) The many faces of H89: a review. Cardiovasc Drug Rev 24:261-274 (Pubitemid 46435008)
14. Louis S, Saward L, Zahradka P (2011) Both AT(1) and AT(2) receptors mediate proliferation and migration of porcine vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 301:H746-H756
15. Mehta PK, Griendling KK (2007) Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 292:C82-C97 (Pubitemid 46127306)
16. Mifune M, Ohtsu H, Suzuki H, Nakashima H, Brailoiu E, Dun NJ, Frank GD, Inagami T, Higashiyama S, Thomas WG, Eckhart AD, Dempsey PJ, Eguchi S (2005) G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor. J Biol Chem 280:26592-26599 (Pubitemid 41022257)
17. Moon MC, Molnar K, Yau L, Zahradka P (2004) Perivascular delivery of losartan with surgical fibrin glue prevents neointimal hyperplasia after arterial injury. J Vasc Surg 40:130-137 (Pubitemid 38813073)
18. Murray AJ (2008) Pharmacological PKA inhibition: all may not be what it seems. Sci Signal 1:re4
19. Naqvi S, Macdonald A, McCoy CE, Darragh J, Reith AD, Arthur JS (2012) Characterization of the cellular action of the MSK inhibitor SB-747651A. Biochem J 441:347-357
20. Newby AC, Zaltsman AB (2000) Molecular mechanisms in intimal hyperplasia. J Pathol 190:300-309 (Pubitemid 30141376)
21. Norata GD, Pirillo A, Callegari E, Hamsten A, Catapano AL, Eriksson P (2003) Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL. Cardiovasc Res 59:169-180 (Pubitemid 36776383)
22. Ono H, Ichiki T, Ohtsubo H, Fukuyama K, Imayama I, Iino N, Masuda S, Hashiguchi Y, Takeshita A, Sunagawa K (2006) CAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells. Hypertens Res 29:39-47
23. Owens GK (2007) Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity. Novartis Found Symp 283:174-191, discussion 191-3, 238-41
24. Owens GK, Kumar MS, Wamhoff BR (2004) Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84:767-801 (Pubitemid 38823766)
25. Pearce LR, Komander D, Alessi DR (2010) The nuts and bolts of AGC protein kinases. Nat Rev Mol Cell Biol 11:9-22
26. Penn RB, Parent JL, Pronin AN, Panettieri RA Jr, Benovic JL (1999) Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness. J Pharmacol Exp Ther 288:428-437 (Pubitemid 29119648)
27. Saward L, Zahradka P (1997a) Angiotensin II activates phosphatidylinositol 3-kinase in vascular smooth muscle cells. Circ Res 81:249-257 (Pubitemid 27342492)
28. Saward L, Zahradka P (1997b) Coronary artery smooth muscle in culture: migration of heterogeneous cell populations from vessel wall. Mol Cell Biochem 176:53-59 (Pubitemid 27491466)
29. Schauer IE, Knaub LA, Lloyd M, Watson PA, Gliwa C, Lewis KE, Chait A, Klemm DJ, Gunter JM, Bouchard R, McDonald TO, O'Brien KD, Reusch JE (2010) CREB downregulation in vascular disease: a common response to cardiovascular risk. Arterioscler Thromb Vasc Biol 30:733-741
30. Shaywitz AJ, GreenbergME (1999) CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68:821-861 (Pubitemid 29449210)
31. Sunga PS, Rabkin SW (1991) Reversal of angiotensin II effect on the cyclic adenosine 3′,5′ monophosphate response to isoprenaline in cardiac hypertrophy. Cardiovasc Res 25:965-968
32. Sutcliffe EL, Bunting KL, He YQ, Li J, Phetsouphanh C, Seddiki N, Zafar A, Hindmarsh EJ, Parish CR, Kelleher AD, McInnes RL, Taya T, Milburn PJ, Rao S (2011) Chromatin-associated protein kinase C-theta regulates an inducible gene expression program and microRNAs in human T lymphocytes. Mol Cell 41:704-719
33. Tokunou T, Shibata R, Kai H, Ichiki T, Morisaki T, Fukuyama K, Ono H, Iino N, Masuda S, Shimokawa H, Egashira K, Imaizumi T, Takeshita A (2003) Apoptosis induced by inhibition of cyclic AMP response element-binding protein in vascular smooth muscle cells. Circulation 108:1246-1252 (Pubitemid 37099995)
34. Touyz RM, Schiffrin EL (2000) Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 52:639-672
35. Vermeulen L, Vanden BergheW, Beck IM, De Bosscher K, Haegeman G (2009) The versatile role of MSKs in transcriptional regulation. Trends Biochem Sci 34:311-318
36. Walton KM, Rehfuss RP, Chrivia JC, Lochner JE, Goodman RH (1992) A dominant repressor of cyclic adenosine 3′,5′-monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the cAMP-mediated induction of the somatostatin promoter in vivo. Mol Endocrinol 6:647-655
37. Watson PA, Nesterova A, Burant CF, Klemm DJ, Reusch JE (2001) Diabetes-related changes in cAMP response element-binding protein content enhance smooth muscle cell proliferation and migration. J Biol Chem 276:46142-46150
38. Wilson DP, Saward L, Zahradka P, Cheung PK (1999) Angiotensin II receptor antagonists prevent neointimal proliferation in a porcine coronary artery organ culture model. Cardiovasc Res 42:761-772 (Pubitemid 29298146)
39. Yang J, Jiang H, Chen SS, Chen J, Li WQ, Xu SK, Wang JC (2010) Lentivirus-mediated RNAi targeting CREB binding protein attenuates neointimal formation and promotes re-endothelialization in balloon injured rat carotid artery. Cell Physiol Biochem 26:441-448
40. Yau L, Zahradka P (2003) PGE(2) stimulates vascular smoothmuscle cell proliferation via the EP2 receptor. Mol Cell Endocrinol 203:77-90 (Pubitemid 36627590)
41. Yau L, Litchie B, Thomas S, Storie B, Yurkova N, Zahradka P (2003) Endogenous mono-ADP-ribosylation mediates smooth muscle cell proliferation and migration via protein kinase N-dependent induction of c-fos expression. Eur J Biochem 270:101-110 (Pubitemid 36061254)