-
1
-
-
84867218450
-
A transcription factor-based mechanism for mouse heterochromatin formation
-
PMID:22983563
-
Bulut-Karslioglu A, Perrera V, Scaranaro M, de la Rosa-Velazquez IA, van de Nobelen S, Shukeir N, Popow J, Gerle B, Opravil S, Pagani M, et al. A transcription factor-based mechanism for mouse heterochromatin formation. Nat Struct Mol Biol 2012; 19:1023-30; PMID:22983563; http://dx.doi. org/10.1038/nsmb.2382
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 1023-1030
-
-
Bulut-Karslioglu, A.1
Perrera, V.2
Scaranaro, M.3
de la Rosa-Velazquez, I.A.4
van de Nobelen, S.5
Shukeir, N.6
Popow, J.7
Gerle, B.8
Opravil, S.9
Pagani, M.10
-
2
-
-
84884694093
-
N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing
-
PMID:24068969
-
Schiza V, Molina-Serrano D, Kyriakou D, Hadjiantoniou A, Kirmizis A. N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing. PLoS Genet 2013; 9:e1003805; PMID:24068969; http://dx.doi. org/10.1371/journal.pgen.1003805
-
(2013)
PLoS Genet
, vol.9
-
-
Schiza, V.1
Molina-Serrano, D.2
Kyriakou, D.3
Hadjiantoniou, A.4
Kirmizis, A.5
-
3
-
-
84892785163
-
Glutamine methylation in histone H2A is an RNApolymerase-I-dedicated modification
-
PMID:24352239
-
Tessarz P, Santos-Rosa H, Robson SC, Sylvestersen KB, Nelson CJ, Nielsen ML, Kouzarides T. Glutamine methylation in histone H2A is an RNApolymerase-I-dedicated modification. Nature 2014; 505:564-8; PMID:24352239; http://dx.doi. org/10.1038/nature12819
-
(2014)
Nature
, vol.505
, pp. 564-568
-
-
Tessarz, P.1
Santos-Rosa, H.2
Robson, S.C.3
Sylvestersen, K.B.4
Nelson, C.J.5
Nielsen, M.L.6
Kouzarides, T.7
-
4
-
-
84890220396
-
Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelialto-Mesenchymal Transition
-
PMID:24239292
-
Millanes-Romero A, Herranz N, Perrera V, Iturbide A, Loubat-Casanovas J, Gil J, Jenuwein T, García de Herreros A, Peiró S. Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelialto-Mesenchymal Transition. Mol Cell 2013; 52:746-57; PMID:24239292; http://dx.doi.org/10.1016/j. molcel.2013.10.015
-
(2013)
Mol Cell
, vol.52
, pp. 746-757
-
-
Millanes-Romero, A.1
Herranz, N.2
Perrera, V.3
Iturbide, A.4
Loubat-Casanovas, J.5
Gil, J.6
Jenuwein, T.7
de Herreros García, A.8
Peiró, S.9
-
5
-
-
84860751681
-
Lysyl oxidase-like 2 deaminates lysine 4 in histone H3
-
PMID:22483618
-
Herranz N, Dave N, Millanes-Romero A, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Di Croce L, García de Herreros A, et al. Lysyl oxidase-like 2 deaminates lysine 4 in histone H3. Mol Cell 2012; 46:369-76; PMID:22483618; http://dx.doi.org/10.1016/j.molcel.2012.03.002
-
(2012)
Mol Cell
, vol.46
, pp. 369-376
-
-
Herranz, N.1
Dave, N.2
Millanes-Romero, A.3
Morey, L.4
Díaz, V.M.5
Lórenz-Fonfría, V.6
Gutierrez-Gallego, R.7
Jerónimo, C.8
Di Croce, L.9
de Herreros García, A.10
-
6
-
-
84885393469
-
Transcriptional regulation by Polycomb group proteins
-
PMID:24096405
-
Di Croce L, Helin K. Transcriptional regulation by Polycomb group proteins. Nat Struct Mol Biol 2013; 20:1147-55; PMID:24096405; http://dx.doi. org/10.1038/nsmb.2669
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 1147-1155
-
-
Di Croce, L.1
Helin, K.2
-
7
-
-
84855516244
-
Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells
-
PMID:22226355
-
Morey L, Pascual G, Cozzuto L, Roma G, Wutz A, Benitah SA, Di Croce L. Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 2012; 10:47-62; PMID:22226355; http://dx.doi.org/10.1016/j. stem.2011.12.006
-
(2012)
Cell Stem Cell
, vol.10
, pp. 47-62
-
-
Morey, L.1
Pascual, G.2
Cozzuto, L.3
Roma, G.4
Wutz, A.5
Benitah, S.A.6
Di Croce, L.7
-
8
-
-
84873167174
-
RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells
-
PMID:23273917
-
Morey L, Aloia L, Cozzuto L, Benitah SA, Di Croce L. RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells. Cell Rep 2013; 3:60-9; PMID:23273917; http://dx.doi.org/10.1016/j.celrep.2012.11.026
-
(2013)
Cell Rep
, vol.3
, pp. 60-69
-
-
Morey, L.1
Aloia, L.2
Cozzuto, L.3
Benitah, S.A.4
Di Croce, L.5
-
9
-
-
84870833161
-
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
-
PMID:23104054
-
Ballaré C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G, Liefke R, Simon B, Shi Y, Gozani O, et al. Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nat Struct Mol Biol 2012; 19:1257-65; PMID:23104054; http://dx.doi. org/10.1038/nsmb.2434
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 1257-1265
-
-
Ballaré, C.1
Lange, M.2
Lapinaite, A.3
Martin, G.M.4
Morey, L.5
Pascual, G.6
Liefke, R.7
Simon, B.8
Shi, Y.9
Gozani, O.10
-
10
-
-
84859183250
-
MacroH2A in stem cells: A story beyond gene repression
-
PMID:22449192
-
Creppe C, Posavec M, Douet J, Buschbeck M. MacroH2A in stem cells: a story beyond gene repression. Epigenomics 2012; 4:221-7; PMID:22449192; http://dx.doi.org/10.2217/epi.12.8
-
(2012)
Epigenomics
, vol.4
, pp. 221-227
-
-
Creppe, C.1
Posavec, M.2
Douet, J.3
Buschbeck, M.4
-
11
-
-
73549105474
-
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing
-
PMID:20008927
-
Gamble MJ, Frizzell KM, Yang C, Krishnakumar R, Kraus WL. The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing. Genes Dev 2010; 24:21-32; PMID:20008927; http://dx.doi. org/10.1101/gad.1876110
-
(2010)
Genes Dev
, vol.24
, pp. 21-32
-
-
Gamble, M.J.1
Frizzell, K.M.2
Yang, C.3
Krishnakumar, R.4
Kraus, W.L.5
-
12
-
-
70349804469
-
The histone variant macroH2A is an epigenetic regulator of key developmental genes
-
PMID:19734898
-
Buschbeck M, Uribesalgo I, Wibowo I, Rué P, Martin D, Gutiérrez A, Morey L, Guigó R, López-Schier H, Di Croce L. The histone variant macroH2A is an epigenetic regulator of key developmental genes. Nat Struct Mol Biol 2009; 16:1074-9; PMID:19734898; http://dx.doi.org/10.1038/nsmb.1665
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1074-1079
-
-
Buschbeck, M.1
Uribesalgo, I.2
Wibowo, I.3
Rué, P.4
Martin, D.5
Gutiérrez, A.6
Morey, L.7
Guigó, R.8
López-Schier, H.9
Di Croce, L.10
-
13
-
-
84879786192
-
MacroH2A--an epigenetic regulator of cancer
-
PMID:23531411
-
Cantariño N, Douet J, Buschbeck M. MacroH2A--an epigenetic regulator of cancer. Cancer Lett 2013; 336:247-52; PMID:23531411; http://dx.doi. org/10.1016/j.canlet.2013.03.022
-
(2013)
Cancer Lett
, vol.336
, pp. 247-252
-
-
Cantariño, N.1
Douet, J.2
Buschbeck, M.3
-
14
-
-
77951428293
-
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
-
PMID:20300060
-
Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, Blais A, Brand M, Ge K, Dilworth FJ. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J 2010; 29:1401-11; PMID:20300060; http://dx.doi. org/10.1038/emboj.2010.37
-
(2010)
EMBO J
, vol.29
, pp. 1401-1411
-
-
Seenundun, S.1
Rampalli, S.2
Liu, Q.C.3
Aziz, A.4
Palii, C.5
Hong, S.6
Blais, A.7
Brand, M.8
Ge, K.9
Dilworth, F.J.10
-
15
-
-
84860351082
-
The transcriptional and epigenomic foundations of ground state pluripotency
-
PMID:22541430
-
Marks H, Kalkan T, Menafra R, Denissov S, Jones K, Hofemeister H, Nichols J, Kranz A, Stewart AF, Smith A, et al. The transcriptional and epigenomic foundations of ground state pluripotency. Cell 2012; 149:590-604; PMID:22541430; http://dx.doi. org/10.1016/j.cell.2012.03.026
-
(2012)
Cell
, vol.149
, pp. 590-604
-
-
Marks, H.1
Kalkan, T.2
Menafra, R.3
Denissov, S.4
Jones, K.5
Hofemeister, H.6
Nichols, J.7
Kranz, A.8
Stewart, A.F.9
Smith, A.10
-
16
-
-
84884133672
-
Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells
-
PMID:23850244
-
Habibi E, Brinkman AB, Arand J, Kroeze LI, Kerstens HHD, Matarese F, Lepikhov K, Gut M, Brun-Heath I, Hubner NC, et al. Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells. Cell Stem Cell 2013; 13:360-9; PMID:23850244; http://dx.doi.org/10.1016/j.stem.2013.06.002
-
(2013)
Cell Stem Cell
, vol.13
, pp. 360-369
-
-
Habibi, E.1
Brinkman, A.B.2
Arand, J.3
Kroeze, L.I.4
Kerstens, H.H.D.5
Matarese, F.6
Lepikhov, K.7
Gut, M.8
Brun-Heath, I.9
Hubner, N.C.10
-
17
-
-
84873507172
-
Bayesian inference of spatial organizations of chromosomes
-
PMID:23382666
-
Hu M, Deng K, Qin Z, Dixon J, Selvaraj S, Fang J, Ren B, Liu JS. Bayesian inference of spatial organizations of chromosomes. PLoS Comput Biol 2013; 9:e1002893; PMID:23382666; http://dx.doi. org/10.1371/journal.pcbi.1002893
-
(2013)
PLoS Comput Biol
, vol.9
-
-
Hu, M.1
Deng, K.2
Qin, Z.3
Dixon, J.4
Selvaraj, S.5
Fang, J.6
Ren, B.7
Liu, J.S.8
-
18
-
-
84890023970
-
Wholegenome haplotype reconstruction using proximityligation and shotgun sequencing
-
PMID:24185094
-
Selvaraj S, R Dixon J, Bansal V, Ren B. Wholegenome haplotype reconstruction using proximityligation and shotgun sequencing. Nat Biotechnol 2013; 31:1111-8; PMID:24185094; http://dx.doi. org/10.1038/nbt.2728
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1111-1118
-
-
Selvaraj, S.1
R Dixon, J.2
Bansal, V.3
Ren, B.4
-
19
-
-
84894279323
-
Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing
-
Fothcoming; PMID: 24486021
-
Liang J, Lacroix L, Gamot A, Cuddapah S, Queille S, Lhoumaud P, Lepetit P, Martin P, Vogelmann J, Court F, et al. Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing. Mol Cell 2014; Fothcoming; PMID: 24486021; http://dx.doi. org/10.1016/j.molcel.2013.12.0
-
(2014)
Mol Cell
-
-
Liang, J.1
Lacroix, L.2
Gamot, A.3
Cuddapah, S.4
Queille, S.5
Lhoumaud, P.6
Lepetit, P.7
Martin, P.8
Vogelmann, J.9
Court, F.10
-
20
-
-
84859051225
-
Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA
-
PMID:22405650
-
Guetg C, Scheifele F, Rosenthal F, Hottiger MO, Santoro R. Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA. Mol Cell 2012; 45:790-800; PMID:22405650; http://dx.doi. org/10.1016/j.molcel.2012.01.024
-
(2012)
Mol Cell
, vol.45
, pp. 790-800
-
-
Guetg, C.1
Scheifele, F.2
Rosenthal, F.3
Hottiger, M.O.4
Santoro, R.5
-
21
-
-
84868206265
-
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
-
PMID:23064413
-
Landan G, Cohen NM, Mukamel Z, Bar A, Molchadsky A, Brosh R, Horn-Saban S, Zalcenstein DA, Goldfinger N, Zundelevich A, et al. Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues. Nat Genet 2012; 44:1207-14; PMID:23064413; http://dx.doi.org/10.1038/ ng.2442
-
(2012)
Nat Genet
, vol.44
, pp. 1207-1214
-
-
Landan, G.1
Cohen, N.M.2
Mukamel, Z.3
Bar, A.4
Molchadsky, A.5
Brosh, R.6
Horn-Saban, S.7
Zalcenstein, D.A.8
Goldfinger, N.9
Zundelevich, A.10
-
22
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
PMID:21706001
-
Hansen KD, Timp W, Bravo HC, Sabunciyan S, Langmead B, McDonald OG, Wen B, Wu H, Liu Y, Diep D, et al. Increased methylation variation in epigenetic domains across cancer types. Nat Genet 2011; 43:768-75; PMID:21706001; http://dx.doi. org/10.1038/ng.865
-
(2011)
Nat Genet
, vol.43
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
Sabunciyan, S.4
Langmead, B.5
McDonald, O.G.6
Wen, B.7
Wu, H.8
Liu, Y.9
Diep, D.10
-
23
-
-
59149083658
-
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells
-
PMID:19151716
-
Wen B, Wu H, Shinkai Y, Irizarry RA, Feinberg AP. Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet 2009; 41:246-50; PMID:19151716; http://dx.doi.org/10.1038/ng.297
-
(2009)
Nat Genet
, vol.41
, pp. 246-250
-
-
Wen, B.1
Wu, H.2
Shinkai, Y.3
Irizarry, R.A.4
Feinberg, A.P.5
-
24
-
-
79961023271
-
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
-
PMID:21725293
-
McDonald OG, Wu H, Timp W, Doi A, Feinberg AP. Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition. Nat Struct Mol Biol 2011; 18:867-74; PMID:21725293; http:// dx.doi.org/10.1038/nsmb.2084
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 867-874
-
-
McDonald, O.G.1
Wu, H.2
Timp, W.3
Doi, A.4
Feinberg, A.P.5
-
25
-
-
84858414016
-
Regulated noise in the epigenetic landscape of development and disease
-
PMID:22424224
-
Pujadas E, Feinberg AP. Regulated noise in the epigenetic landscape of development and disease. Cell 2012; 148:1123-31; PMID:22424224; http://dx.doi. org/10.1016/j.cell.2012.02.045
-
(2012)
Cell
, vol.148
, pp. 1123-1131
-
-
Pujadas, E.1
Feinberg, A.P.2
-
26
-
-
84881086323
-
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
-
PMID:23760024
-
Timp W, Feinberg AP. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer 2013; 13:497-510; PMID:23760024; http://dx.doi.org/10.1038/ nrc3486
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 497-510
-
-
Timp, W.1
Feinberg, A.P.2
-
27
-
-
0041382819
-
Genetics supersedes epigenetics in colon cancer phenotype
-
PMID:12957287
-
Yamashita K, Dai T, Dai Y, Yamamoto F, Perucho M. Genetics supersedes epigenetics in colon cancer phenotype. Cancer Cell 2003; 4:121-31; PMID:12957287; http://dx.doi.org/10.1016/ S1535-6108(03)00190-9
-
(2003)
Cancer Cell
, vol.4
, pp. 121-131
-
-
Yamashita, K.1
Dai, T.2
Dai, Y.3
Yamamoto, F.4
Perucho, M.5
-
28
-
-
33644825262
-
Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
-
PMID:16530704
-
Suzuki K, Suzuki I, Leodolter A, Alonso S, Horiuchi S, Yamashita K, Perucho M. Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell 2006; 9:199-207; PMID:16530704; http://dx.doi.org/10.1016/j. ccr.2006.02.016
-
(2006)
Cancer Cell
, vol.9
, pp. 199-207
-
-
Suzuki, K.1
Suzuki, I.2
Leodolter, A.3
Alonso, S.4
Horiuchi, S.5
Yamashita, K.6
Perucho, M.7
-
29
-
-
84870552726
-
DNA demethylation in normal colon tissue predicts predisposition to multiple cancers
-
PMID:22310288
-
Kamiyama H, Suzuki K, Maeda T, Koizumi K, Miyaki Y, Okada S, Kawamura YJ, Samuelsson JK, Alonso S, Konishi F, et al. DNA demethylation in normal colon tissue predicts predisposition to multiple cancers. Oncogene 2012; 31:5029-37; PMID:22310288; http://dx.doi.org/10.1038/onc.2011.652
-
(2012)
Oncogene
, vol.31
, pp. 5029-5037
-
-
Kamiyama, H.1
Suzuki, K.2
Maeda, T.3
Koizumi, K.4
Miyaki, Y.5
Okada, S.6
Kawamura, Y.J.7
Samuelsson, J.K.8
Alonso, S.9
Konishi, F.10
-
30
-
-
84880263616
-
Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4
-
PMID:22945651
-
Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, Gu L, Muley T, Meister M, Dienemann H, et al. Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4. Oncogene 2013; 32:3329-38; PMID:22945651; http://dx.doi. org/10.1038/onc.2012.344
-
(2013)
Oncogene
, vol.32
, pp. 3329-3338
-
-
Scherf, D.B.1
Sarkisyan, N.2
Jacobsson, H.3
Claus, R.4
Bermejo, J.L.5
Peil, B.6
Gu, L.7
Muley, T.8
Meister, M.9
Dienemann, H.10
-
31
-
-
84856555311
-
A DNA methylation fingerprint of 1628 human samples
-
PMID:21613409
-
Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, Yamamoto H, Hidalgo M, Tan AC, Galm O, et al. A DNA methylation fingerprint of 1628 human samples. Genome Res 2012; 22:407-19; PMID:21613409; http://dx.doi. org/10.1101/gr.119867.110
-
(2012)
Genome Res
, vol.22
, pp. 407-419
-
-
Fernandez, A.F.1
Assenov, Y.2
Martin-Subero, J.I.3
Balint, B.4
Siebert, R.5
Taniguchi, H.6
Yamamoto, H.7
Hidalgo, M.8
Tan, A.C.9
Galm, O.10
-
32
-
-
79551605803
-
Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages
-
PMID:21179004
-
Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth FJ, Gentleman R, et al. Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages. EMBO J 2011; 30:494-509; PMID:21179004; http://dx.doi.org/10.1038/ emboj.2010.342
-
(2011)
EMBO J
, vol.30
, pp. 494-509
-
-
Palii, C.G.1
Perez-Iratxeta, C.2
Yao, Z.3
Cao, Y.4
Dai, F.5
Davison, J.6
Atkins, H.7
Allan, D.8
Dilworth, F.J.9
Gentleman, R.10
-
33
-
-
80054984945
-
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
-
PMID:21964340
-
Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI, Robson SC, Chung CW, Hopf C, Savitski MM, et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 2011; 478:529-33; PMID:21964340; http://dx.doi.org/10.1038/ nature10509
-
(2011)
Nature
, vol.478
, pp. 529-533
-
-
Dawson, M.A.1
Prinjha, R.K.2
Dittmann, A.3
Giotopoulos, G.4
Bantscheff, M.5
Chan, W.I.6
Robson, S.C.7
Chung, C.W.8
Hopf, C.9
Savitski, M.M.10
-
34
-
-
84893735484
-
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia
-
(Forthcoming); PMID:24220271
-
Dawson MA, Gudgin EJ, Horton SJ, Giotopoulos G, Meduri E, Robson S, Cannizzaro E, Osaki H, Wiese M, Putwain S, et al. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia. Leukemia 2013; (Forthcoming); PMID:24220271; http:// dx.doi.org/10.1038/leu.2013.338
-
(2013)
Leukemia
-
-
Dawson, M.A.1
Gudgin, E.J.2
Horton, S.J.3
Giotopoulos, G.4
Meduri, E.5
Robson, S.6
Cannizzaro, E.7
Osaki, H.8
Wiese, M.9
Putwain, S.10
-
35
-
-
84891879120
-
BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms
-
PMID:23929215
-
Wyspianska BS, Bannister AJ, Barbieri I, Nangalia J, Godfrey A, Calero-Nieto FJ, Robson S, Rioja I, Li J, Wiese M, et al. BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms. Leukemia 2014; 28:88-97; PMID:23929215; http://dx.doi. org/10.1038/leu.2013.234
-
(2014)
Leukemia
, vol.28
, pp. 88-97
-
-
Wyspianska, B.S.1
Bannister, A.J.2
Barbieri, I.3
Nangalia, J.4
Godfrey, A.5
Calero-Nieto, F.J.6
Robson, S.7
Rioja, I.8
Li, J.9
Wiese, M.10
-
36
-
-
84884685624
-
Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni
-
PMID:24086136
-
Marek M, Kannan S, Hauser A-T, Moraes Mourão M, Caby S, Cura V, Stolfa DA, Schmidtkunz K, Lancelot J, Andrade L, et al. Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni. PLoS Pathog 2013; 9:e1003645; PMID:24086136; http:// dx.doi.org/10.1371/journal.ppat.1003645
-
(2013)
PLoS Pathog
, vol.9
-
-
Marek, M.1
Kannan, S.2
Hauser, A.-T.3
Moraes Mourão, M.4
Caby, S.5
Cura, V.6
Stolfa, D.A.7
Schmidtkunz, K.8
Lancelot, J.9
Andrade, L.10
-
37
-
-
78650861867
-
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia
-
PMID:21205967
-
Fabbri M, Bottoni A, Shimizu M, Spizzo R, Nicoloso MS, Rossi S, Barbarotto E, Cimmino A, Adair B, Wojcik SE, et al. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA 2011; 305:59-67; PMID:21205967; http://dx.doi. org/10.1001/jama.2010.1919
-
(2011)
JAMA
, vol.305
, pp. 59-67
-
-
Fabbri, M.1
Bottoni, A.2
Shimizu, M.3
Spizzo, R.4
Nicoloso, M.S.5
Rossi, S.6
Barbarotto, E.7
Cimmino, A.8
Adair, B.9
Wojcik, S.E.10
-
38
-
-
84907485172
-
MicroRNAs in Cancer
-
PMID:24079833
-
Di Leva G, Garofalo M, Croce CM. MicroRNAs in Cancer. Annu Rev Pathol 2013; 9:287-314; PMID:24079833; http://dx.doi.org/10.1146/ annurev-pathol-012513-104715
-
(2013)
Annu Rev Pathol
, vol.9
, pp. 287-314
-
-
Di Leva, G.1
Garofalo, M.2
Croce, C.M.3
-
39
-
-
84904977196
-
Impaired DICER1 function promotes stemness and metastasis in colon cancer
-
(Forthcoming); PMID:24096488
-
Iliou MS, da Silva-Diz V, Carmona FJ, Ramalho-Carvalho J, Heyn H, Villanueva A, Muñoz P, Esteller M. Impaired DICER1 function promotes stemness and metastasis in colon cancer. Oncogene 2013; (Forthcoming); PMID:24096488; http://dx.doi. org/10.1038/onc.2013.398
-
(2013)
Oncogene
-
-
Iliou, M.S.1
da Silva-Diz, V.2
Carmona, F.J.3
Ramalho-Carvalho, J.4
Heyn, H.5
Villanueva, A.6
Muñoz, P.7
Esteller, M.8
-
40
-
-
84863718299
-
Intronic RNAs mediate EZH2 regulation of epigenetic targets
-
PMID:22659877
-
Guil S, Soler M, Portela A, Carrère J, Fonalleras E, Gómez A, Villanueva A, Esteller M. Intronic RNAs mediate EZH2 regulation of epigenetic targets. Nat Struct Mol Biol 2012; 19:664-70; PMID:22659877; http://dx.doi.org/10.1038/nsmb.2315
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 664-670
-
-
Guil, S.1
Soler, M.2
Portela, A.3
Carrère, J.4
Fonalleras, E.5
Gómez, A.6
Villanueva, A.7
Esteller, M.8
-
41
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
PMID:21386836
-
Rodríguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med 2011; 17:330-9; PMID:21386836; http://dx.doi.org/10.1038/ nm.2305
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodríguez-Paredes, M.1
Esteller, M.2
-
42
-
-
84901508481
-
Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
-
(Forthcoming); PMID:23770855
-
Rodriguez-Paredes M, Martinez de Paz A, Simó-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vázquez-Cedeira M, Lazo PA, Carneiro F, et al. Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis. Oncogene 2013; (Forthcoming); PMID:23770855; http://dx.doi.org/10.1038/ onc.2013.239
-
(2013)
Oncogene
-
-
Rodriguez-Paredes, M.1
de Paz Martinez, A.2
Simó-Riudalbas, L.3
Sayols, S.4
Moutinho, C.5
Moran, S.6
Villanueva, A.7
Vázquez-Cedeira, M.8
Lazo, P.A.9
Carneiro, F.10
-
43
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNAguided endonuclease
-
PMID:23360966
-
Cho SW, Kim S, Kim JM, Kim JS. Targeted genome engineering in human cells with the Cas9 RNAguided endonuclease. Nat Biotechnol 2013; 31:230-2; PMID:23360966; http://dx.doi.org/10.1038/ nbt.2507
-
(2013)
Nat Biotechnol
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.S.4
-
44
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
PMID:23643243
-
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 2013; 153:910-8; PMID:23643243; http://dx.doi. org/10.1016/j.cell.2013.04.025
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
45
-
-
84885107449
-
Global transcriptional and translational repression in human-embryonic-stem-cellderived Rett syndrome neurons
-
PMID:24094325
-
Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok S-M, Feldman DA, Bateup HS, Gao Q, et al. Global transcriptional and translational repression in human-embryonic-stem-cellderived Rett syndrome neurons. Cell Stem Cell 2013; 13:446-58; PMID:24094325; http://dx.doi. org/10.1016/j.stem.2013.09.001
-
(2013)
Cell Stem Cell
, vol.13
, pp. 446-458
-
-
Li, Y.1
Wang, H.2
Muffat, J.3
Cheng, A.W.4
Orlando, D.A.5
Lovén, J.6
Kwok, S.-M.7
Feldman, D.A.8
Bateup, H.S.9
Gao, Q.10
-
46
-
-
0033601073
-
Methylation-induced repression--belts, braces, and chromatin
-
PMID:10589672
-
Bird AP, Wolffe AP. Methylation-induced repression--belts, braces, and chromatin. Cell 1999; 99:451-4; PMID:10589672; http://dx.doi.org/10.1016/ S0092-8674(00)81532-9
-
(1999)
Cell
, vol.99
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
47
-
-
84875490185
-
Cancer genome landscapes
-
PMID:23539594
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr., Kinzler KW. Cancer genome landscapes. Science 2013; 339:1546-58; PMID:23539594; http://dx.doi.org/10.1126/science.1235122
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz Jr., L.A.5
Kinzler, K.W.6
-
48
-
-
78651162036
-
Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis
-
PMID:14172992
-
Allfrey VG, Faulkner R, Mirsky AE. Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc Natl Acad Sci U S A 1964; 51:786-94; PMID:14172992; http://dx.doi. org/10.1073/pnas.51.5.786
-
(1964)
Proc Natl Acad Sci U S A
, vol.51
, pp. 786-794
-
-
Allfrey, V.G.1
Faulkner, R.2
Mirsky, A.E.3
-
49
-
-
84895875371
-
Citrullination regulates pluripotency and histone H1 binding to chromatin
-
PMID:24463520
-
Christophorou MA, Castelo-Branco G, Halley-Stott RP, Oliveira CS, Loos R, Radzisheuskaya A, Mowen KA, Bertone P, Silva JC, Zernicka-Goetz M, et al. Citrullination regulates pluripotency and histone H1 binding to chromatin. Nature 2014; PMID:24463520; http://dx.doi.org/10.1038/ nature12942
-
(2014)
Nature
-
-
Christophorou, M.A.1
Castelo-Branco, G.2
Halley-Stott, R.P.3
Oliveira, C.S.4
Loos, R.5
Radzisheuskaya, A.6
Mowen, K.A.7
Bertone, P.8
Silva, J.C.9
Zernicka-Goetz, M.10
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