Combined effect of hyperfiltration and renin angiotensin system activation on development of chronic kidney disease in diabetic db/db mice

BMC Nephrology

Volumn 15, Issue 1, 2014, Pages

  Hartono, Stella P ^a   Knudsen, Bruce E ^a   Lerman, Lilach O ^a   Textor, Stephen C ^a   Grande, Joseph P ^a  

^a MAYO CLINIC   (United States)

Author keywords

Diabetes; Hypertension; Inflammation; Renal artery stenosis; Renovascular hypertension

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; CREATININE; FIBRONECTIN; INTERLEUKIN 6;

ALBUMIN BLOOD LEVEL; ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DISEASE SEVERITY; ELEVATED BLOOD PRESSURE; FIBROSING ALVEOLITIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY ARTERY STENOSIS; KIDNEY HYPERTROPHY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PLASMA RENIN ACTIVITY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENOVASCULAR HYPERTENSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; TRANSMISSION ELECTRON MICROSCOPY; ULTRAFILTRATION; UNINEPHRECTOMY; ANIMAL; C57BL MOUSE; CHRONIC KIDNEY FAILURE; COMPLICATION; GLOMERULUS FILTRATION RATE; HYPERTENSION, RENOVASCULAR; KIDNEY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; GLOMERULAR FILTRATION RATE; HYPERTENSION, RENOVASCULAR; KIDNEY; MALE; MICE; MICE, INBRED C57BL; RENAL INSUFFICIENCY, CHRONIC; RENIN-ANGIOTENSIN SYSTEM;

EID: 84899113419     PISSN: None     EISSN: 14712369     Source Type: Journal    
DOI: 10.1186/1471-2369-15-58     Document Type: Article

References (42)

1. Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention 2011
2. Prevalence of renal artery stenosis in subjects with type 2 diabetes and coexistent hypertension. Valabhji J, Robinson S, Poulter C, Robinson AC, Kong C, Henzen C, Gedroyc WM, Feher MD, Elkeles RS, Diab Care 2000 23 4 539 543 10.2337/diacare.23.4.539 (Pubitemid 30185801)
3. Renal artery stenosis by three-dimensional magnetic resonance angiography in type 2 diabetics with uncontrolled hypertension and chronic renal insufficiency: prevalence and effect on renal function. Myers DI, Poole LJ, Imam K, Scheel PJ, Eustace JA, Am J Kidney Dis 2003 41 2 351 359 10.1053/ajkd.2003.50043 12552496 (Pubitemid 36152453)
4. Renal artery stenosis in hypertensive patients with or without type 2 diabetes: a comparative magnetic resonance angiography study. Hajsadeghi S, Fereshtehnejad SM, Pourshirmohammadi-Sabzevari M, Khamseh ME, Noohi F, Arch Iran Med 2009 12 3 250 255 19400602
5. Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension. Warner GM, Cheng J, Knudsen BE, Gray CE, Deibel A, Juskewitch JE, Lerman LO, Textor SC, Nath KA, Grande JP, Am J Physiol Renal Physiol 2012 302 11 1455 F1464 10.1152/ajprenal.00645.2011 22378822
6. Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the 1 or 2 Na-K-ATPase ouabain-binding site. Lorenz JN, Lasko VM, Nieman ML, Damhoff T, Prasad V, Beierwaltes WH, Lingrel JB, Am J Physiol Renal Physiol 2011 301 3 615 F621 10.1152/ajprenal.00158.2011 21632957
7. Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. II. Effects of renal mass reduction. Levine DZ, Iacovitti M, Robertson SJ, Am J Physiol Regul Integr Comp Physiol 2008 294 6 1840 R1846 10.1152/ajpregu.00457.2007 18417648
8. The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice. Ninichuk V, Khandoga AG, Segerer S, Loetscher P, Schlapbach A, Revesz L, Feifel R, Khandoga A, Krombach F, Nelson PJ, Schlondorff D, Anders HJ, Am J Pathol 2007 170 4 1267 1276 10.2353/ajpath.2007.060937 17392166 (Pubitemid 47339334)
9. AT1 antagonism and renin inhibition in mice: pivotal role of targeting angiotensin II in chronic kidney disease. Fraune C, Lange S, Krebs C, Hölzel A, Baucke J, Divac N, Schwedhelm E, Streichert T, Velden J, Garrelds IM, Danser AH, Frenay AR, van Goor H, Jankowski V, Stahl R, Nguyen G, Wenzel UO, Am J Physiol Renal Physiol 2012 303 7 1037 F1048 10.1152/ajprenal.00672.2011 22791343
10. Renovascular hypertension and ischemic nephropathy. Textor SC, Lerman L, Am J Hypertens 2010 23 11 1159 1169 10.1038/ajh.2010.174 20864945
11. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Kobori H, Nangaku M, Navar LG, Nishiyama A, Pharmacol Rev 2007 59 3 251 287 10.1124/pr.59.3.3 17878513 (Pubitemid 47481436)
12. The renin-angiotensin-aldosterone system: cardiorenal effects and implications for renal and cardiovascular disease states. Brewster UC, Setaro JF, Perazella MA, Am J Med Sci 2003 326 1 15 24 10.1097/00000441-200307000-00003 12861121 (Pubitemid 36870293)
13. Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition. Langham RG, Kelly DJ, Gow RM, Zhang Y, Cordonnier DJ, Pinel N, Zaoui P, Gilbert RE, Diab Care 2006 29 12 2670 2675 10.2337/dc06-0911 (Pubitemid 44912197)
14. Redox signaling is an early event in the pathogenesis of renovascular hypertension. Hartono SP, Knudsen BE, Zubair AS, Nath KA, Textor SJ, Lerman LO, Grande JP, Int J Mol Sci 2013 14 9 18640 18656 10.3390/ijms140918640 24025423
15. Unilateral nodular diabetic glomerulosclerosis (Kimmelstiel-Wilson): report of a case. Berkman J, Rifkin H, Metabol Clin Exp 1973 22 5 715 722 10.1016/0026-0495(73)90243-6
16. Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension. Cheng J, Zhou W, Warner GM, Knudsen BE, Garovic VD, Gray CE, Lerman LO, Platt JL, Romero JC, Textor SC, Nath KA, Grande JP, Am J Physiol Ren Physiol 2009 297 4 1055 F1068 10.1152/ajprenal.90439.2008
17. Early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney. Urbieta-Caceres VH, Lavi R, Zhu XY, Crane JA, Textor SC, Lerman A, Lerman LO, Am J Physiol Ren Physiol 2010 299 1 135 F140 10.1152/ajprenal.00159.2010
18. Inflammatory and injury signals released from the post-stenotic human kidney. Eirin A, Gloviczki ML, Tang H, Gossl M, Jordan KL, Woollard JR, Lerman A, Grande JP, Textor SC, Lerman LO, Eur Heart J 2013 34 7 540 548 10.1093/eurheartj/ehs197 22771675
19. Increased Circulating Inflammatory Endothelial Cells in Blacks With Essential Hypertension. Eirin A, Zhu XY, Woollard JR, Herrmann SM, Gloviczki ML, Saad A, Juncos LA, Calhoun DA, Rule AD, Lerman A, Textor SC, Lerman LO, Hypertension 2013 62 3 585 591 10.1161/HYPERTENSIONAHA.113.01621 23798347
20. Intact renal afferent arteriolar autoregulatory responsiveness in db/db mice. Park S, Bivona BJ, Feng Y, Lazartigues E, Harrison-Bernard LM, Am J Physiol Ren Physiol 2008 295 5 1504 F1511 10.1152/ajprenal.90417.2008
21. Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells. Brezniceanu ML, Liu F, Wei CC, Chenier I, Godin N, Zhang SL, Filep JG, Ingelfinger JR, Chan JS, Diabetes 2008 57 2 451 459 17977949
22. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R, FASEB J 2000 14 3 439 447 10698958 (Pubitemid 30143162)
23. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Guo C, Martinez-Vasquez D, Mendez GP, Toniolo MF, Yao TM, Oestreicher EM, Kikuchi T, Lapointe N, Pojoga L, Williams GH, Ricchiuti V, Adler GK, Endocrinology 2006 147 11 5363 5373 10.1210/en.2006-0944 16901964 (Pubitemid 44790591)
24. Nilvadipine attenuates mesangial expansion and glomerular hypertrophy in diabetic db/db mice, a model for type 2 diabetes. Moriyama T, Oka K, Ueda H, Imai E, Clin Exp Nephrol 2004 8 3 230 236 10.1007/s10157-004-0303-1 15480900 (Pubitemid 39421372)
25. Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice. Su W, Guo Z, Randall DC, Cassis L, Brown DR, Gong MC, Am J Physiol Heart Circ Physiol 2008 295 4 1634 H1641 10.1152/ajpheart.00257.2008 18708447
26. Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model. Wang D, Warner GM, Yin P, Knudsen BE, Cheng J, Butters KA, Lien KR, Gray CE, Garovic VD, Lerman LO, Textor SC, Nath KA, Simari RD, Grande JP, Am J Physiol Heart Circ Physiol 2013 304 7 938 F947
27. Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse. Hong SW, Isono M, Chen S, Iglesias-De La Cruz MC, Han DC, Ziyadeh FN, Am J Pathol 2001 158 5 1653 1663 10.1016/S0002-9440(10)64121-1 11337363 (Pubitemid 32422930)
28. Studies in the diabetic mutant mouse. VI. Evolution of glomerular lesions and associated proteinuria. Like AA, Lavine RL, Poffenbarger PL, Chick WL, Am J Pathol 1972 66 2 193 224 5009970
29. Thiaproline reduces glomerular basement membrane thickness and collagen accumulation in the db/db mouse. Lubec B, Rokitansky A, Hayde M, Aufricht C, Wagner U, Mallinger WR, Hoger H, Lubec G, Nephron 1994 66 3 333 336 10.1159/000187832 8190187 (Pubitemid 24054825)
30. In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage. Mitani H, Ishizaka N, Aizawa T, Ohno M, Usui S, Suzuki T, Amaki T, Mori I, Nakamura Y, Sato M, Nangaku M, Hirata Y, Nagai R, Hypertension 2002 39 4 838 843 10.1161/01.HYP.0000013734.33441.EA 11967236 (Pubitemid 34437536)
31. Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice. Jennings BL, Anderson LJ, Estes AM, Yaghini FA, Fang XR, Porter J, Gonzalez FJ, Campbell WB, Malik KU, Hypertension 2012 59 2 348 354 10.1161/HYPERTENSIONAHA.111.183301 22184325
32. Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice. Ninichuk V, Clauss S, Kulkarni O, Schmid H, Segerer S, Radomska E, Eulberg D, Buchner K, Selve N, Klussmann S, Anders HJ, Am J Pathol 2008 172 3 628 637 10.2353/ajpath.2008.070601 18258851 (Pubitemid 351354536)
33. Tubular atrophy, interstitial fibrosis, and inflammation in type 2 diabetic db/db mice. An accelerated model of advanced diabetic nephropathy. Ninichuk V, Kulkarni O, Clauss S, Anders H, Eur J Med Res 2007 12 8 351 355 17933712 (Pubitemid 47365152)
34. Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice. Chow FY, Nikolic-Paterson DJ, Ma FY, Ozols E, Rollins BJ, Tesch GH, Diabetologia 2007 50 2 471 480 10.1007/s00125-006-0497-8 17160673
35. IL6 suppression provides renal protection independent of blood pressure in a murine model of salt-sensitive hypertension. Manhiani MM, Quigley JE, Socha MJ, Motamed K, Imig JD, Kidney Blood Press Res 2007 30 4 195 202 10.1159/000104094 17575466 (Pubitemid 47076216)
36. Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy. Kanamori H, Matsubara T, Mima A, Sumi E, Nagai K, Takahashi T, Abe H, Iehara N, Fukatsu A, Okamoto H, Kita T, Doi T, Arai H, Biochem Biophys Res Commun 2007 360 4 772 777 10.1016/j.bbrc.2007.06.148 17631861 (Pubitemid 47077388)
37. Possible relationship of monocyte chemoattractant protein-1 with diabetic nephropathy. Banba N, Nakamura T, Matsumura M, Kuroda H, Hattori Y, Kasai K, Kidney Int 2000 58 2 684 690 10.1046/j.1523-1755.2000.00214.x 10916091 (Pubitemid 30620017)
38. Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy. Wada T, Furuichi K, Sakai N, Iwata Y, Yoshimoto K, Shimizu M, Takeda SI, Takasawa K, Yoshimura M, Kida H, Kobayashi KI, Mukaida N, Naito T, Matsushima K, Yokoyama H, Kidney Int 2000 58 4 1492 1499 10.1046/j.1523-1755.2000.00311.x 11012884
39. Serum monocyte chemoattractant protein-1 and monocyte adhesion molecules in type 1 diabetic patients with nephropathy. Kiyici S, Erturk E, Budak F, Ersoy C, Tuncel E, Duran C, Oral B, Sigirci D, Imamoglu S, Arch Med Res 2006 37 8 998 1003 10.1016/j.arcmed.2006.06.002 17045117 (Pubitemid 44512061)
40. Monitoring urinary levels of monocyte chemotactic and activating factor reflects disease activity of lupus nephritis. Wada T, Yokoyama H, Su SB, Mukaida N, Iwano M, Dohi K, Takahashi Y, Sasaki T, Furuichi K, Segawa C, Hisada Y, Ohta S, Takasawa K, Kobayashi K, Matsushima K, Kidney Int 1996 49 3 761 767 10.1038/ki.1996.105 8648917 (Pubitemid 26093085)
41. Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria. Eddy AA, Giachelli CM, Kidney Int 1995 47 6 1546 1557 10.1038/ki.1995.218 7643523
42. Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells. Takaya K, Koya D, Isono M, Sugimoto T, Sugaya T, Kashiwagi A, Haneda M, Am J Physiol Renal Physiol 2003 284 5 1037 F1045 12517735