High-fat diet, obesity and sudden cardiac death

Acta Physiologica

Volumn 211, Issue 1, 2014, Pages 13-16

  Morrow, J P ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; DEVELOPED COUNTRY; DIABETIC PATIENT; EDITORIAL; FAT CONTENT; FATTY ACID BLOOD LEVEL; HEART ARRHYTHMIA; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART REPOLARIZATION; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPID BLOOD LEVEL; LIPID DIET; LONG QT SYNDROME 1; NONHUMAN; OBESITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SUDDEN CARDIAC DEATH; ANIMAL; HEART VENTRICLE REMODELING; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSIOLOGY; WEIGHT GAIN;

ANIMALS; ARRHYTHMIAS, CARDIAC; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; HYPERTROPHY, LEFT VENTRICULAR; MALE; VENTRICULAR REMODELING; WEIGHT GAIN;

EID: 84899111326     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12276     Document Type: Editorial

References (40)

1. Abel, E.D., Litwin, S.E. & Sweeney, G. 2008. Cardiac remodeling in obesity. Physiol Rev 88, 389-419.
2. Albert, C.M., Chae, C.U., Grodstein, F., Rose, L.M., Rexrode, K.M., Ruskin, J.N., Stampfer, M.J. & Manson, J.E. 2003. Prospective study of sudden cardiac death among women in the United States. Circulation 107, 2096-2101.
3. Anderson, E.J., Kypson, A.P., Rodriguez, E., Anderson, C.A., Lehr, E.J. & Neufer, P.D. 2009. Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54, 1891-1898.
4. Battiprolu, P.K., Hojayev, B., Jiang, N., Wang, Z.V., Luo, X., Iglewski, M., Shelton, J.M., Gerard, R.D., Rothermel, B.A., Gillette, T.G., Lavandero, S. & Hill, J.A. 2012. Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice. J Clin Invest 122, 1109-1118.
5. Brunner, M., Peng, X., Liu, G.X., Ren, X.Q., Ziv, O., Choi, B.R., Mathur, R., Hajjiri, M., Odening, K.E., Steinberg, E. et al. 2008. Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome. J Clin Invest 118, 2246-2259.
6. Chiu, H.C., Kovacs, A., Ford, D.A., Hsu, F.F., Garcia, R., Herrero, P., Saffitz, J.E. & Schaffer, J.E. 2001. A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest 107, 813-822.
7. Chiu, H.C., Kovacs, A., Blanton, R.M., Han, X., Courtois, M., Weinheimer, C.J., Yamada, K.A., Brunet, S., Xu, H., Nerbonne, J.M. et al. 2005. Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ Res 96, 225-233.
8. Connelly, K.A., Kelly, D.J., Zhang, Y., Prior, D.L., Martin, J., Cox, A.J., Thai, K., Feneley, M.P., Tsoporis, J., White, K.E., Krum, H. & Gilbert, R.E. 2007. Functional, structural and molecular aspects of diastolic heart failure in the diabetic (mRen-2)27 rat. Cardiovasc Res 76, 280-291.
9. Erickson, J.R., Pereira, L., Wang, L., Han, G., Ferguson, A., Dao, K., Copeland, R.J., Despa, F., Hart, G.W., Ripplinger, C.M. & Bers, D.M. 2013. Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature 502, 372-376.
10. Filippi, A., Sessa, E. Jr, Mazzaglia, G., Pecchioli, S. Jr, Capocchi, R. Jr, Caprari, F., Scivales, A. & Cricelli, C. 2008. Out of hospital sudden cardiac death in Italy: a population-based case-control study. J Cardiovasc Med (Hagerstown) 9, 595-600.
11. Goldberg, I.J., Trent, C.M. & Schulze, P.C. 2012. Lipid metabolism and toxicity in the heart. Cell Metab 15, 805-812.
12. Hookana, E., Junttila, M.J., Puurunen, V.P., Tikkanen, J.T., Kaikkonen, K.S., Kortelainen, M.L., Myerburg, R.J. & Huikuri, H.V. 2011. Causes of nonischemic sudden cardiac death in the current era. Heart Rhythm 8, 1570-1575.
13. Huang, H., Amin, V., Gurin, M., Wan, E., Thorp, E., Homma, S. & Morrow, J.P. 2013. Diet-induced obesity causes long QT and reduces transcription of voltage-gated potassium channels. J Mol Cell Cardiol 59C, 151-158.
14. Jouven, X., Desnos, M., Guerot, C. & Ducimetiere, P. 1999. Predicting sudden death in the population: the Paris Prospective Study I. Circulation 99, 1978-1983.
15. Jouven, X., Charles, M.A., Desnos, M. & Ducimetiere, P. 2001. Circulating nonesterified fatty acid level as a predictive risk factor for sudden death in the population. Circulation 104, 756-761.
16. Lengyel, C., Virag, L., Biro, T., Jost, N., Magyar, J., Biliczki, P., Kocsis, E., Skoumal, R., Nanasi, P.P., Toth, M., Kecskemeti, V., Papp, J.G. & Varro, A. 2007. Diabetes mellitus attenuates the repolarization reserve in mammalian heart. Cardiovasc Res 73, 512-520.
17. Lengyel, C., Virag, L., Kovacs, P.P., Kristof, A., Pacher, P., Kocsis, E., Koltay, Z.M., Nanasi, P.P., Toth, M., Kecskemeti, V., Papp, J.G., Varro, A. & Jost, N. 2008. Role of slow delayed rectifier K+-current in QT prolongation in the alloxan-induced diabetic rabbit heart. Acta Physiol (Oxf) 192, 359\x96368.
18. Lopaschuk, G.D., Ussher, J.R., Folmes, C.D., Jaswal, J.S. & Stanley, W.C. 2010. Myocardial fatty acid metabolism in health and disease. Physiol Rev 90, 207-258.
19. Lu, Z., Ballou, L.M., Jiang, Y.P., Cohen, I.S. & Lin, R.Z. 2011. Restoration of defective L-type Ca2 + current in cardiac myocytes of type 2 diabetic db/db mice by Akt and PKC-iota. J Cardiovasc Pharmacol 58, 439-445.
20. Luo, M., Guan, X., Luczak, E.D., Lang, D., Kutschke, W., Gao, Z., Yang, J., Glynn, P., Sossalla, S., Swaminathan, P.D. et al. 2013. Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. J Clin Invest 123, 1262-1274.
21. Marionneau, C., Aimond, F., Brunet, S., Niwa, N., Finck, B., Kelly, D.P. & Nerbonne, J.M. 2008. PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy. J Mol Cell Cardiol 44, 1002-1015.
22. Messerli, F.H., Nunez, B.D., Ventura, H.O. & Snyder, D.W. 1987. Overweight and sudden death. Increased ventricular ectopy in cardiopathy of obesity. Arch Intern Med 147, 1725-1728.
23. Morrow, J.P., Katchman, A., Son, N.H., Trent, C.M., Khan, R., Shiomi, T., Huang, H., Amin, V., Lader, J.M., Vasquez, C., Morley, G.E., D'Armiento, J., Homma, S., Goldberg, I.J. & Marx, S.O. 2011. Mice with cardiac overexpression of peroxisome proliferator-activated receptor gamma have impaired repolarization and spontaneous fatal ventricular arrhythmias. Circulation 124, 2812-2821.
24. Netticadan, T., Temsah, R.M., Kent, A., Elimban, V. & Dhalla, N.S. 2001. Depressed levels of Ca2 + -cycling proteins may underlie sarcoplasmic reticulum dysfunction in the diabetic heart. Diabetes 50, 2133-2138.
25. Nishiyama, A., Ishii, D.N., Backx, P.H., Pulford, B.E., Birks, B.R. & Tamkun, M.M. 2001. Altered K(+) channel gene expression in diabetic rat ventricle: isoform switching between Kv4.2 and Kv1.4. Am J Physiol Heart Circ Physiol 281, H1800-H1807.
26. Okin, P.M., Devereux, R.B., Lee, E.T., Galloway, J.M. & Howard, B.V. 2004. Electrocardiographic repolarization complexity and abnormality predict all-cause and cardiovascular mortality in diabetes: the strong heart study. Diabetes 53, 434-440.
27. Oliver, M.F., Kurien, V.A. & Greenwood, T.W. 1968. Relation between serum-free-fatty acids and arrhythmias and death after acute myocardial infarction. Lancet 1, 710-714.
28. Qin, D., Huang, B., Deng, L., El-Adawi, H., Ganguly, K., Sowers, J.R. & El-Sherif, N. 2001. Downregulation of K(+) channel genes expression in type I diabetic cardiomyopathy. Biochem Biophys Res Commun 283, 549-553.
29. Ramirez, A.H., Schildcrout, J.S., Blakemore, D.L., Masys, D.R., Pulley, J.M., Basford, M.A., Roden, D.M. & Denny, J.C. 2011. Modulators of normal electrocardiographic intervals identified in a large electronic medical record. Heart Rhythm 8, 271-277.
30. Reuter, H., Gronke, S., Adam, C., Ribati, M., Brabender, J., Zobel, C., Frank, K.F., Wippermann, J., Schwinger, R.H., Brixius, K. & Muller-Ehmsen, J. 2008. Sarcoplasmic Ca2 + release is prolonged in nonfailing myocardium of diabetic patients. Mol Cell Biochem 308, 141-149.
31. Sharma, S., Adrogue, J.V., Golfman, L., Uray, I., Lemm, J., Youker, K., Noon, G.P., Frazier, O.H. & Taegtmeyer, H. 2004. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. FASEB J 18, 1692-1700.
32. Shimoni, Y., Firek, L., Severson, D. & Giles, W. 1994. Short-term diabetes alters K+ currents in rat ventricular myocytes. Circ Res 74, 620-628.
33. Shimoni, Y., Chuang, M., Abel, E.D. & Severson, D.L. 2004. Gender-dependent attenuation of cardiac potassium currents in type 2 diabetic db/db mice. J Physiol 555, 345-354.
34. Suarez, J., Scott, B. & Dillmann, W.H. 2008. Conditional increase in SERCA2a protein is able to reverse contractile dysfunction and abnormal calcium flux in established diabetic cardiomyopathy. Am J Physiol Regul Integr Comp Physiol 295, R1439-R1445.
35. Szczepaniak, L.S., Victor, R.G., Orci, L. & Unger, R.H. 2007. Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. Circ Res 101, 759-767.
36. Van Wagoner, D.R., Pond, A.L., McCarthy, P.M., Trimmer, J.S. & Nerbonne, J.M. 1997. Outward K+ current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation. Circ Res 80, 772-781.
37. Watanabe, E., Arakawa, T., Uchiyama, T., Tong, M., Yasui, K., Takeuchi, H., Terasawa, T., Kodama, I. & Hishida, H. 2007. Prognostic significance of circadian variability of RR and QT intervals and QT dynamicity in patients with chronic heart failure. Heart Rhythm 4, 999-1005.
38. Yaras, N., Ugur, M., Ozdemir, S., Gurdal, H., Purali, N., Lacampagne, A., Vassort, G. & Turan, B. 2005. Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2 + homeostasis in rat heart. Diabetes 54, 3082-3088.
39. Zemva, A. & Zemva, Z. 2000. Ventricular ectopic activity, left ventricular mass, hyperinsulinemia, and intracellular magnesium in normotensive patients with obesity. Angiology 51, 101-106.
40. Zhang, Y., Xiao, J., Lin, H., Luo, X., Wang, H., Bai, Y., Wang, J., Zhang, H., Yang, B. & Wang, Z. 2007. Ionic mechanisms underlying abnormal QT prolongation and the associated arrhythmias in diabetic rabbits: a role of rapid delayed rectifier K+ current. Cell Physiol Biochem 19, 225-238.