Randomized controlled trial of physical activity, cognition, and walking in multiple sclerosis

Journal of Neurology

Volumn 261, Issue 2, 2014, Pages 363-372

  Sandroff, Brian M ^a   Klaren, Rachel E ^a   Pilutti, Lara A ^a   Dlugonski, Deirdre ^a   Benedict, Ralph H B ^b   Motl, Robert W ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cognition; Multiple sclerosis; Physical activity; Walking

Indexed keywords

ADULT; ARTICLE; BEHAVIOR CHANGE; BEHAVIOR THERAPY; COGNITION; COGNITIVE DEFECT; COMMUNICATION SOFTWARE; CONTROLLED STUDY; DISABILITY; EXPANDED DISABILITY STATUS SCALE; FEMALE; FUNCTION TEST; GOAL ATTAINMENT; GROUP DYNAMICS; HOSPITAL ADMISSION; HUMAN; INTERNATIONAL PHYSICAL ACTIVITY QUESTIONNAIRE; INTERNET; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MOTOR PERFORMANCE; MULTIPLE SCLEROSIS; NEUROPSYCHOLOGICAL TEST; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SELF MONITORING; SELF REPORT; SIX MINUTE WALK TEST; SYMBOL DIGIT MODALITIES TEST; TELETHERAPY; VIDEOCONFERENCING; WALKING;

ADULT; COGNITION; DATA INTERPRETATION, STATISTICAL; DISABILITY EVALUATION; EXERCISE THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR ACTIVITY; MULTIPLE SCLEROSIS; NEUROPSYCHOLOGICAL TESTS; PATIENT COMPLIANCE; PSYCHOMOTOR PERFORMANCE; TREATMENT OUTCOME; WALKING;

EID: 84899084615     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-013-7204-8     Document Type: Article

References (43)

1. Benedict RHB, Zivadinov R (2011) Risk factors for and management of cognitive dysfunction in multiple sclerosis. Nat Rev Neurosci 7(6):332-342
2. Motl RW, Sandroff BM, Benedict RHB (2011) Cognitive dysfunction and multiple sclerosis: developing a rationale for considering the efficacy of exercise training. Mult Scler 201117(9):1034-1040
3. Motl RW, Gappmaier E, Nelson K, Benedict RHB (2011) Physical activity and cognitive function in multiple sclerosis. J Sport Exerc Psychol 33(5):734-741
4. Sandroff BM, Dlugonski D, Pilutti LA, Pula JH, Benedict RHB, Motl RW (2014) Physical activity is associated with cognitive processing speed in persons with multiple sclerosis. Mult Scler Relat Disord 3(1):123-128
5. Ratey JJ, Loehr JE (2011) The positive impact of physical activity on cognition during adulthood: a review of underlying mechanisms, evidence and recommendations. Rev Neurosci 22(2):171-185
6. Benedict RHB, Holtzer R, Motl RW, Foley FW, Kaur S, Hojnacki D, Weinstock-Guttman B (2011) Upper and lower extremity motor function and cognitive impairment in multiple sclerosis. J Int Neuropsychol Soc 17(4):643-653
7. D'Orio VL, Foley FW, Armentano F, Picone MA, Kim S, Holtzer R (2012) Cognitive and motor functioning in patients with multiple sclerosis: neuropsychological predictors of walking speed and falls. J Neurol Sci 316:42-46
8. Snook EM, Motl RW (2009) Effect of exercise training on walking mobility in multiple sclerosis: a meta-analysis. Neurorehabil Neural Repair 23(2):108-116
9. Motl RW, Dlugonski D, Wojcicki TR, McAuley E, Mohr DC (2011) Internet intervention for increasing physical activity in persons with multiple sclerosis. Mult Scler 17(1):116-128
10. Dlugonski D, Motl RW, Mohr DC, Sandroff BM (2012) Internet-delivered behavioral intervention to increase physical activity in persons with multiple sclerosis: sustainability and secondary outcomes. Psychol Health Med 17(6):636-651
11. Dlugonski D, Motl RW, McAuley E (2011) Increasing physical activity in multiple sclerosis: replicating Internet intervention effects using objective and self-report outcomes. J Rehabil Res Dev 48(9):1129-1136
12. Motl RW, McAuley E, Dlugonski D (2012) Reactivity in baseline accelerometer data from a physical activity behavioral intervention. Health Psychol 31(2):172-175
13. Sandroff BM, Pilutti LA, Dlugonski D, Motl RW (2013) Physical activity and information processing speed in persons with multiple sclerosis: a prospective study. Ment Health Phys Act 6(3):205-211
14. Motl RW, Pilutti L, Sandroff BM, Dlugonski D, Sosnoff JJ, Pula JH (2013) Accelerometry as a measure of walking behavior in multiple sclerosis. Acta Neurol Scand 127(6):384-390
15. Thomas S, Reading J, Shephard RJ (1992) Revision of the physical activity readiness questionnaire (PAR-Q). Can J Sport Sci 17(4):338-345
16. Smith A (1982) Symbol digit modalities test: manual. Western Psychological Services, Los Angeles
17. Rao SM, Leo GJ, Bernarndin L, Unverzagt F (1991) Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction. Neurology 41:685-691
18. Benedict RH, Smerbeck A, Parikh R, Rodgers J, Cadavid D, Erlanger D (2012) Reliability and equivalence of alternate forms for the Symbol Digit Modalities Test: implications for multiple sclerosis clinical trials. Mult Scler 18(9):1320-1325
19. Benedict RH, Walton MK (2012) Evaluating cognitive outcome measures for MS clinical trials: what is a clinically meaningful change? Mult Scler 18(12):1673-1679
20. Goldman MD, Marrie RA, Cohen JA (2008) Evaluation of the six-minute walk in multiple sclerosis subjects and healthy controls. Mult Scler 14(3):383-390 (Pubitemid 351676433)
21. Wetzel JL, Fry DK, Pfalzer LA (2011) Six-minute walk test for persons with mild or moderate disability from multiple sclerosis: performance and explanatory factors. Physiother Can 63(2):166-180
22. Craig CL, Marshall AL, Sjostrom M et al (2003) International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 35:1381-1395 (Pubitemid 36936159)
23. Sandroff BM, Dlugonski D, Weikert M, Suh Y, Balantrapu S, Motl RW (2012) Physical activity and multiple sclerosis: new insights regarding inactivity. Acta Neurol Scand 126(4):256-262
24. Gosney JL, Scott JA, Snook EM, Motl RW (2007) Physical activity and multiple sclerosis: validity of self-report and objective measures. Fam Community Health 30:144-150
25. Motl RW, McAuley E, Snook EM, Scott JA (2006) Validity of physical activity measures in ambulatory individuals with multiple sclerosis. Disabil Rehabil 28:1151-1156 (Pubitemid 44364097)
26. Weikert M, Motl RW, Suh Y, McAuley E, Wynn D (2009) Accelerometry in persons with multiple sclerosis: measurement of physical activity or walking mobility? J Neurol Sci 260:6-11
27. Snook EM, Motl RW, Gliottoni RC (2009) The effect of walking mobility on the measurement of physical activity using accelerometry in multiple sclerosis. Clin Rehabil 23:248-258
28. Hadjimichael O, Kerns RD, Rizzo MA, Cutter G, Vollmer T (2007) Persistent pain and uncomfortable sensations in persons with multiple sclerosis. Pain 127(1-2):35-41 (Pubitemid 44959422)
29. Learmonth YC, Motl RW, Sandroff BM, Pula JH, Cadavid D (2013) Validation of patient determined disease steps (PDDS) scale scores in persons with multiple sclerosis. BMC Neurol 13(1):37
30. Marrie RA, Goldman M (2007) Validity of performance scales for disability assessment in multiple sclerosis. Mult Scler 13(9):1176-1182 (Pubitemid 351541422)
31. Marrie RA, Cutter G, Tyry T, Vollmer T, Campagnolo D (2006) Does multiple sclerosis-associated disability differ between races? Neurology 66(8):1235-1240 (Pubitemid 43739710)
32. Confavreux C, Vukusic S (2006) Natural history of multiple sclerosis: a unifying concept. Brain 129:606-616 (Pubitemid 43278223)
33. Bandura A (2004) Health promotion by social cognitive means. Health Educ Behav 31:143-164
34. Donner A, Klar N (1994) Cluster randomization trials in epidemiology: theory and application. J Stat Plan Inference 42(1-2):37-56
35. Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Lawrence Erlbaum Associates, Hillsdale
36. Morrow SA, Drake A, Zivadinov R, Munschauer F, Weinstock-Guttman B, Benedict RHB (2010) Predicting loss of employment over three years in multiple sclerosis: clinically meaningful cognitive decline. Clin Neuropsychol 24:1131-1145
37. Morrow SA, Jurgensen S, Forrestal F, Munchauer FE, Benedict RH (2011) Effects of acute relapses on neuropsychological status in multiple sclerosis patients. J Neurol 258(9):1603-1608
38. Stuifbergen AK, Becker H, Perez F, Morison J, Kullberg V, Todd A (2012) A randomized controlled trial of a cognitive rehabilitation intervention for persons with multiple sclerosis. Clin Rehabil 26(10):882-893
39. Glanz BI, Healy BC, Hviid LE, Chitnis T, Weiner HL (2012) Cognitive deterioration in patients with early multiple sclerosis: a 5-year study. J Neurol Neurosurg Psychiatry 83(1):38-43
40. Drake AS, Weinstock-Guttman B, Morrow SA, Hojnacki D, Munschauer FE, Benedict RHB (2010) Psychometrics and normative data for the Multiple Sclerosis Functional Composite: replacing the PASAT with the Symbol Digit Modalities Test. Mult Scler 16:228-237
41. Motl RW, Goldman MD, Benedict RH (2010) Walking impairment in patients with multiple sclerosis: exercise training as a treatment option. Neuropsychiatr Dis Treat 6:767-774
42. Hebert JR, Corboy JR, Manago MM, Schenkman M (2011) Effects of vestibular rehabilitation on multiple sclerosis-related fatigue and upright postural control: a randomized controlled trial. Phys Ther 91(8):1166-1183
43. Smith PJ, Blumenthal JA, Hoffman BM, Cooper H, Strauman TA, Welsh-Bohmer K, Browndyke JN, Sherwood A (2010) Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosom Med 72(3):239-252