Dietary l-methionine supplementation mitigates gamma-radiation induced global DNA hypomethylation: Enhanced metabolic flux towards S-adenosyl-l-methionine (SAM) biosynthesis increases genomic methylation potential

Food and Chemical Toxicology

Volumn 69, Issue , 2014, Pages 46-54

  Batra, Vipen ^a   Verma, Poonam ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Diet; DNA methylation; L methionine; Metabolism; Radiation toxicity

Indexed keywords

5 METHYLDEOXYCYTIDINE; CHOLINE; COBALT 60; DNA METHYLTRANSFERASE; FOLIC ACID; METHIONINE; METHIONINE ADENOSYLTRANSFERASE; METHIONINE SYNTHASE; S ADENOSYLMETHIONINE;

AMINO ACID BLOOD LEVEL; AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DIET SUPPLEMENTATION; DNA METHYLATION; DNA MODIFICATION; ENZYME ACTIVITY; GAMMA RADIATION; HISTOPATHOLOGY; IN VIVO STUDY; LIVER HOMOGENATE; MALE; METABOLIC FLUX ANALYSIS; METABOLITE; MOUSE; NONHUMAN; RADIATION EXPOSURE; STRESS; ANIMAL; DIET; DRUG EFFECTS;

ANIMALS; DIET; DNA METHYLATION; METHIONINE;

EID: 84899083920     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.03.040     Document Type: Article

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