Association of sleep apnea with clinically silent microvascular brain tissue changes in acute cerebral ischemia

Journal of Neurology

Volumn 261, Issue 2, 2014, Pages 343-349

  Kepplinger, Jessica ^a   Barlinn, Kristian ^a,b   Boehme, Amelia K ^c   Gerber, Johannes ^a   Puetz, Volker ^a   Pallesen, Lars Peder ^a   Schrempf, Wiebke ^a   Dzialowski, Imanuel ^a,d   Albright, Karen C ^b,c   Alexandrov, Andrei V ^b   Reichmann, Heinz ^a   Von Kummer, Ruediger ^a   Bodechtel, Ulf ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA HOSPITAL   (United States)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Acute stroke; Leukoaraiosis; Silent brain infarction; Sleep apnea

Indexed keywords

ADULT; APNEA HYPOPNEA INDEX; ARTICLE; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; DIFFUSION WEIGHTED IMAGING; DISEASE ASSOCIATION; EPWORTH SLEEPINESS SCALE; FEMALE; HOSPITAL DISCHARGE; HUMAN; LACUNAR STROKE; LEUKOARAIOSIS; MAJOR CLINICAL STUDY; MALE; MICROVASCULAR ISCHEMIA; MIDDLE AGED; MULTICHANNEL RECORDER; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANKIN SCALE; RECALL; SLEEP DISORDERED BREATHING; TRANSIENT ISCHEMIC ATTACK;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; BODY MASS INDEX; BRAIN ISCHEMIA; CAPILLARIES; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; ISCHEMIC ATTACK, TRANSIENT; LEUKOARAIOSIS; MALE; MIDDLE AGED; RISK FACTORS; SLEEP APNEA SYNDROMES; STROKE, LACUNAR; THROMBOLYTIC THERAPY; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84899082257     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-013-7200-z     Document Type: Article

References (40)

1. Pantoni L (2010) Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 9:689-701
2. LADIS Study Group (2011) 2001-2011: a decade of the LADIS (Leukoaraiosis And DISability) Study: what have we learned about white matter changes and small-vessel disease? Cerebrovasc Dis 32:577-588
3. Steffens DC, Krishnan KRR, Crump C, Burke GL (2002) Cerebrovascular disease and evolution of depression symptoms in the Cardiovascular Health Study. Stroke 33:1636-1644 (Pubitemid 34619971)
4. Vermeer SE, Hollander M, van Dijk EJ, Hofman A, Koudstaal PJ, Breteler MM (2003) Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study. Stroke 34:1126-1129 (Pubitemid 36547501)
5. Gioia LC, Tollard É, Dubuc V et al (2012) Silent ischemic lesions in young adults with first stroke are associated with recurrent stroke. Neurology 79:1208-1214
6. Putaala J, Haapaniemi E, Kurkinen M, Salonen O, Kaste M, Tatlisumak T (2011) Silent brain infarcts, leukoaraiosis, and long-term prognosis in young ischemic stroke patients. Neurology 76:1742-1749
7. Leonards CO, Ipsen N, Malzahn U, Fiebach JB, Endres M, Ebinger M (2012) White matter lesion severity in mild acute ischemic stroke patients and functional outcome after 1 year. Stroke 43:3046-3051
8. de Jong G, Kessels F, Lodder J (2002) Two types of lacunar infarcts: further arguments from a study on prognosis. Stroke 33:2072-2076 (Pubitemid 34840070)
9. Basile AM, Pantoni L, Pracucci G et al (2006) Age, hypertension, and lacunar stroke are the major determinants of the severity of age-related white matter changes. The LADIS (Leukoaraiosis and Disability in the Elderly) Study. Cerebrovasc Dis 21:315-322 (Pubitemid 44617294)
10. Nishibayashi M, Miyamoto M, Miyamoto T, Suzuki K, Hirata K (2008) Correlation between severity of obstructive sleep apnea and prevalence of silent cerebrovascular lesions. J Clin Sleep Med 4:242-247 (Pubitemid 352039435)
11. Robbins J, Redline S, Ervin A, Walsleben JA, Ding J, Nieto FJ (2005) Associations of sleep-disordered breathing and cerebral changes on MRI. J Clin Sleep Med 1:159-165
12. Eguchi K, Kario K, Hoshide S, Ishikawa J, Morinari M, Shimada K (2005) Nocturnal hypoxia is associated with silent cerebrovascular disease in a high-risk Japanese community-dwelling population. Am J Hypertens 18:1489-1495 (Pubitemid 41566681)
13. Cho ER, Kim H, Seo HS, Suh S, Lee SK, Shin C (2013) Obstructive sleep apnoea as a risk factor for silent cerebral infarction. J Sleep Res 22:452-458
14. Shamsuzzaman AS, Gersh BJ, Somers VK (2003) Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA 290:1906-1914 (Pubitemid 37430608)
15. Hatazawa J, Shimosegawa E, Satoh T, Toyoshima H, Okudera T (1997) Subcortical hypoperfusion associated with asymptomatic white matter lesions on magnetic resonance imaging. Stroke 28:1944-1947 (Pubitemid 27459000)
16. Macey PM, Kumar R, Woo MA, Valladares EM, Yan-Go FL, Harper RM (2008) Brain structural changes in obstructive sleep apnea. Sleep 31:967-977 (Pubitemid 351956936)
17. Kepplinger J, Barlinn K, Albright KC et al (2013) Early sleep apnea screening on a stroke unit is feasible in patients with acute cerebral ischemia. J Neurol 260:1343-1350
18. Adams H, Bendixen B, Kappelle L et al (1993) Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. Toast. Trial of org 10172 in acute stroke treatment. Stroke 24:35-41 (Pubitemid 23014379)
19. Iber C, Ancoli-Israel S, Chesson A, Quan SF, for the American Academy of Sleep Medicine (2007) The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications, 1st ed Westchester, Illinois: American Academy of Sleep Medicine
20. Epstein LJ, Kristo D, Strollo PJ Jr et al (2009) Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 5:263-276
21. Wahlund LO, Barkhof F, Fazekas F et al (2001) European task force on age-related white matter changes. A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke 32:1318-1322 (Pubitemid 32530416)
22. Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V (2005) Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 353:2034-2041 (Pubitemid 41609096)
23. Arzt M, Young T, Finn L, Skatrud JB, Bradley TD (2005) Association of sleep-disordered breathing and the occurrence of stroke. Am J Respir Crit Care Med 172:1447-1451 (Pubitemid 43069819)
24. Redline S, Yenokyan G, Gottlieb DJ et al (2010) Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study. Am J Respir Crit Care Med 182:269-277
25. Davies CW, Crosby JH, Mullins RL et al (2001) Case control study of cerebrovascular damage defined by magnetic resonance imaging in patients with OSA and normal matched control subjects. Sleep 24:715-720 (Pubitemid 32825509)
26. Kiernan TE, Capampangan DJ, Hickey MG, Pearce LA, Aguilar MI (2011) Sleep apnea and white matter disease in hypertensive patients: a case series. Neurologist 17:289-291
27. Schulz UG, Mason RH, Craig SE et al (2013) Leukoaraiosis on MRI in patients with minimally symptomatic obstructive sleep apnoea. Cerebrovasc Dis 35:363-369
28. Kim H, Yun CH, Thomas RJ et al (2013) Obstructive sleep apnea as a risk factor for cerebral white matter change in a middle-aged and older general population. Sleep 36:709-715
29. Harbison J, Gibson GJ, Birchall D, Zammit-Maempel I, Ford GA (2003) White matter disease and sleep-disordered breathing after acute stroke. Neurology 61:959-963 (Pubitemid 37248653)
30. Kim DE, Choi MJ, Kim JT et al (2013) Two different clinical entities of small vessel occlusion in TOAST classification. Clin Neurol Neurosurg. doi:10.1016/j.clineuro.2013.03.005
31. Hassan A, Lansbury A, Catto AJ et al (2002) Angiotensin converting enzyme insertion/deletion genotype is associated with leukoaraiosis in lacunar syndromes. J Neurol Neurosurg Psychiatry 72:343-346
32. Iranzo A, Santamaria J, Berenguer J, Sánchez M, Chamorro A (2002) Prevalence and clinical importance of sleep apnea in the first night after cerebral infarction. Neurology 58:911-916 (Pubitemid 34242067)
33. Alexandrov AV, Nguyen HT, Rubiera M et al (2009) Prevalence and risk factors associated with reversed Robin Hood syndrome in acute ischemic stroke. Stroke 40:2738-2742
34. Palazzo P, Balucani C, Barlinn K et al (2010) Association of reversed Robin Hood syndrome with risk of stroke recurrence. Neurology 75:2003-2008
35. Hermann DM, Bassetti CL (2009) Sleep-related breathing and sleep-wake disturbances in ischemic stroke. Neurology 73:1313-1322
36. Tsivgoulis G, Zhang Y, Alexandrov AW et al (2011) Safety and tolerability of early noninvasive ventilatory correction using bilevel positive airway pressure in acute ischemic stroke. Stroke 42:1030-1034
37. Srijithesh PR, Shukla G, Srivastav A, Goyal V, Singh S, Behari M (2001) Validity of the Berlin Questionnaire in identifying obstructive sleep apnea syndrome when administered to the informants of stroke patients. J Clin Neurosci 18:340-343
38. Kepplinger J, Barlinn K, Kolieskova S et al (2013) Reversal of the neurological deficit in acute stroke with the signal of efficacy trial of auto-BPAP to limit damage from suspected sleep apnea (reverse-STEAL): study protocol for a randomized controlled trial. Trials 14:252
39. Edwards JD, Jacova C, Sepehry AA, Pratt B, Benavente OR (2013) A quantitative systematic review of domain-specific cognitive impairment in lacunar stroke. Neurology 80:315-322
40. Saini M, Ikram K, Hilal S, Qiu A, Venketasubramanian N, Chen C (2012) Silent stroke: not listened to rather than silent. Stroke 43:3102-3104