Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF

Blood

Volumn 123, Issue 16, 2014, Pages 2585-2592

  Lynch, Christopher J ^a   Lane, David A ^a   Luken, Brenda M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; PROTEIN VARIANT; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR A2; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ARTICLE; DIFFERENTIAL SCANNING FLUORIMETRY; DISULFIDE BOND; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; TEMPERATURE; THERMOSTABILITY;

ADAM PROTEINS; BINDING SITES; CALCIUM; DISULFIDES; HEK293 CELLS; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; VON WILLEBRAND FACTOR;

EID: 84899059899     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-11-538173     Document Type: Article

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