Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling

Journal of Virology

Volumn 88, Issue 10, 2014, Pages 5533-5542

  Smith, Jessica L ^a   Stein, David A ^a   Shum, David ^b   Fischer, Matthew A ^a   Radu, Constantin ^b   Bhinder, Bhavneet ^b   Djaballah, Hakim ^b   Nelson, Jay A ^a   Früh, Klaus ^a   Hirsch, Alec J ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 FLUORO 11 (4 METHYLPIPERAZIN 1 YL) 10,11 DIHYDRODIBENZO[B,F]THIEPIN 2 OL; ANTIVIRUS AGENT; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; SEROTONIN 2A RECEPTOR; SEROTONIN ANTAGONIST; SKI 417616; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DENGUE; DENGUE VIRUS 2; DRUG EFFECT; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; IC 50; LIFE CYCLE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SINDBIS VIRUS; VIROGENESIS; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS REPLICATION; WEST NILE FLAVIVIRUS;

ANTIVIRAL AGENTS; DENGUE VIRUS; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, DOPAMINE D4; SIGNAL TRANSDUCTION; SINDBIS VIRUS; VIRUS REPLICATION; WEST NILE VIRUS;

EID: 84899047230     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00365-14     Document Type: Article

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