MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious Hepatitis C virus particles

PLoS Pathogens

Volumn 8, Issue 7, 2012, Pages 21-

  Menzel, Nicolas ^a   Fischl, Wolfgang ^b   Hueging, Kathrin ^a   Bankwitz, Dorothea ^a   Frentzen, Anne ^a   Haid, Sibylle ^a   Gentzsch, Juliane ^a   Kaderali, Lars ^c   Bartenschlager, Ralf ^b   Pietschmann, Thomas ^a  

^a INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE A2 GROUP IV; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE; NITRILE; PLA2G4A PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CATALYSIS; CYTOSOL; DENGUE VIRUS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HEPATITIS C VIRUS; LIPOLYSIS; NONHUMAN; PROGENY; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; RNA INTERFERENCE; RNA REPLICATION; SIGNAL TRANSDUCTION; VIROGENESIS; VIRUS PARTICLE; VIRUS REPLICATION; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; MACROPHAGE; METABOLISM; PHYSIOLOGY; VESICULAR STOMATITIS VIRUS;

DENGUE VIRUS; HEPATITIS C VIRUS;

ARACHIDONIC ACID; BUTADIENES; CELL LINE; DENGUE VIRUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GROUP IV PHOSPHOLIPASES A2; HEPACIVIRUS; HUMANS; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; RNA INTERFERENCE; RNA, SMALL INTERFERING; VESICULOVIRUS; VIRUS REPLICATION;

EID: 84864581005     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002829     Document Type: Article

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