All-trans retinoic acid induces cell-cycle arrest in human cutaneous squamous carcinoma cells by inhibiting the mitogen-activated protein kinase-activated protein 1 pathway

Clinical and Experimental Dermatology

Volumn 39, Issue 3, 2014, Pages 354-360

  Zhang, M L ^a   Tao, Y ^b   Zhou, W Q ^a   Ma, P C ^a   Cao, Y P ^a   He, C D ^c   Wei, J ^a   Li, L J ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN P21; PROTEIN P27; REGULATOR PROTEIN; RETINOIC ACID; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE 1;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL PROLIFERATION ASSAY; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SKIN CARCINOMA; WESTERN BLOTTING; CARCINOMA, SQUAMOUS CELL; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; DRUG EFFECTS; METABOLISM; SKIN NEOPLASMS; TUMOR CELL LINE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FLUORESCENCE ACTIVATED CELL SORTING; LUCIFERASE ASSAY; MTT ASSAY; SQUAMOUS CELL CARCINOMA CELL;

ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; SKIN NEOPLASMS; TRETINOIN;

EID: 84898988320     PISSN: 03076938     EISSN: 13652230     Source Type: Journal    
DOI: 10.1111/ced.12227     Document Type: Article

References (19)

1. Ridky TW,. Nonmelanoma skin cancer. J Am Acad Dermatol 2007; 57: 484-501. (Pubitemid 47239135)
2. Honma M, Kato N, Hashimoto M, et al,. Subungual keratoacanthoma: analysis of cell proliferation and copy number variation of oncogenes compared with periungual squamous cell carcinoma. Clin Exp Dermatol 2011; 36: 57-62.
3. Lomas A, Leonardi-Bee J, Bath-Hextall F,. A systematic review of worldwide incidence of nonmelanoma skin cancer. Br J Dermatol 2012; 166: 1069-80.
4. Bushue N, Wan YJ,. Retinoid pathway and cancer therapeutics. Adv Drug Deliv Rev 2010; 62: 1285-98.
5. Siddikuzzaman Guruvayoorappan C, Berlin Grace VM,. All-trans retinoic acid and cancer. Immunopharmacol Immunotoxicol 2011; 33: 241-9.
6. Harwood CA, Leedham-Green M, Leigh IM, Proby CM,. Low-dose retinoids in the prevention of cutaneous squamous cell carcinomas in organ transplant recipients: a 16-year retrospective study. Arch Dermatol 2005; 141: 456-64. (Pubitemid 40547404)
7. Zhang X, Makino T, Muchemwa FC, et al,. Activation of the extracellular signal-regulated kinases signaling pathway in squamous cell carcinoma of the skin. Biosci Trends 2007; 1: 156-60.
8. Cheepala SB, Yin W, Syed Z, et al,. Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion. Mol Cancer 2009; 8: 27-42.
9. Ke H, Harris R, Coloff JL, et al,. The c-June NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia. Cancer Res 2010; 70: 3080-8.
10. Tilgen W, Boukamp P, Breitkreutz D, et al,. Preservation of morphological, functional, and karyotypic traits during long-term culture and in vivo passage of two human skin squamous cell carcinomas. Cancer Res 1983; 43: 5995-6011. (Pubitemid 14212673)
11. Tao Y, Zhang ML, Ma PC, et al,. Triptolide inhibits proliferation and induces apoptosis of human melanoma A375 cells. Asian Pac J Cancer Prev 2012; 13: 1611-15.
12. Theodosiou M, Laudet V, Schubert M,. From carrot to clinic: an overview of the retinoic acid signaling pathway. Cell Mol Life Sci 2010; 67: 1423-45.
13. Lin XY, He CD, Xiao T, et al,. Acitretin induces apoptosis through CD95 signalling pathway in human cutaneous squamous cell carcinoma cell line SCL-1. J Cell Mol Med 2009; 13: 2888-98.
14. Park SH, Lim JS, Jang KL,. All-trans retinoic acid induces cellular senescence via upregulation of p16, 21, and p27. Cancer Lett 2011; 310: 232-9.
15. Lonardo F, Rusch V, Langenfeld J, et al,. Overexpression of cyclins D1 and E is frequent in bronchial preneoplasia and precedes squamous cell carcinoma development. Cancer Res 1999; 59: 2470-6. (Pubitemid 29242299)
16. Huang K, Huang C, Shan K, et al,. Significance of PC cell-derived growth factor and cyclin D1 expression in cutaneous squamous cell carcinoma. Clin Exp Dermatol 2012; 37: 411-17.
17. Lee HY, Walsh GL, Dawson MI, et al,. All-trans-retinoic acid inhibits June N-terminal kinase-dependent signaling pathways. J Biol Chem 1998; 273: 7066-71. (Pubitemid 28160375)
18. Jia G, Cheng G, Gangahar DM, Agrawal DK,. Involvement of connexin 43 in angiotensin II-induced migration and proliferation of saphenous vein smooth muscle cells via the MAPK-AP-1 signaling pathway. J Mol Cell Cardiol 2008; 44: 882-90.
19. Chen NN, Li Y, Wu ML, et al,. CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells. Exp Dermatol 2012; 21: 13-18.