Purification of biomolecules combining ATPS and membrane chromatography

Food and Bioproducts Processing

Volumn 92, Issue 2, 2014, Pages 152-160

  Puthirasigamany, Mayuratheepan ^a   Hamm, Ines ^a   Van Winssen, Fatma Alexia ^a   Nikbin, Nima ^c   Kreis, Peter ^a,b   Gorak, Andrzej ^a   Zeiner, Tim ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

^b EVONIK INDUSTRIES AG   (Germany)

^c University of Delaware   (United States)

Author keywords

Aqueous two phase extraction; Downstream processing; Membrane chromatography

Indexed keywords

FERMENTATION; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; ION EXCHANGE; MONOCLONAL ANTIBODIES; PROTEINS; PURIFICATION; WASTE MANAGEMENT;

AQUEOUS TWO-PHASE EXTRACTION; BOVINE SERUM ALBUMINS; DOWNSTREAM-PROCESSING; HIGH SALT CONCENTRATION; HYDROPHOBIC INTERACTIONS; MEMBRANE CHROMATOGRAPHY; POLYETHYLENE GLYCOL (PEG); RECOMBINANT MICROORGANISM;

MEMBRANES;

EID: 84898971638     PISSN: 09603085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fbp.2014.03.006     Document Type: Article

References (31)

1. P.A. Albertsson Adv. Protein Chem. 24 1970 309 341
2. P.Å. Albertsson Partition of Cell Particles and Macromolecules: Distribution and Fractionation of Cells 2nd ed. 1971 Wiley-Interscience New York
3. B.A. Andrews, D.M. Head, P. Dunthorne, and J.A. Asenjo Biotechnol. Tech. 4 1990 49 54
4. B.A. Andrews, S. Nielsen, and J.A. Asenjo Bioseparation 6 1996 303 313
5. J.A. Asenjo, and B.A. Andrews J. Chromatogr. A 49 2011 8826 8835
6. J.A. Asenjo, R.E. Turner, S.L. Mistry, and A. Kaul J. Chromatogr. A 668 1994 129 137
7. A.M. Azevedo, P.A.J. Rosa, I.F. Ferreira, and M.R. Aires-Barros J. Biotechnol. 132 2007 209 217
8. A.M. Azevedo, A.G. Gomes, P.A.J. Rosa, I.F. Ferreira, A.M.M.O. Pisco, and M.R. Aires-Barros Sep. Purif. Technol. 65 2009 14 21
9. A.M. Azevedo, P.A.J. Rosa, I.F. Ferreira, and M.R. Aires-Barros Trends Biotechnol. 27 2009 240 247
10. Bäcker, W., Sommerfeld, S., Mutter, M., 2009. Verfahren zur Reinigung therapeutischer Proteine. Patent WO/2009/112149A2.
11. K. Gebauer, J. Thömmes, and M. Kula Biotechnol. Bioeng. 54 1997 181 189
12. J. Hubbuch, and M.-R. Kula J. Non-Equilib. Thermodyn. 32 2007 99 127
13. J.G. Huddleston, H.D. Willauer, and R.D. Rogers J. Chem. Eng. Data 48 2003 1230 1236
14. Nikbin, N., Kreis, P., Górak, A., 2012. Hybrid Process for the Purification of Biomolecules. Patent WO/2012/045331.
15. D. Platis, and N.E. Labrou Biotechnol. J. 4 2009 1320 1327
16. A. Prinz, J. Hönig, I. Schüttmann, H. Zorn, and T. Zeiner Process Biochem. 2013 10.1016/j.procbio.2013.11.006
17. T.M. Przybycien, N.S. Pujar, and L.M. Steele Curr. Opin. Biotechnol. 15 2004 469 478
18. M. Puthirasigamany, M. Wirges, and T. Zeiner Biochem. Eng. J. 70 2013 180 187
19. D. Roper, and E.N. Lightfoot J. Chromatogr. A 702 1995 3 26
20. P.A.J. Rosa, A.M. Azevedo, I.F. Ferreira, J. de Vries, R. Korporaal, H.J. Verhoef, T.J. Visser, and M.R. Aires-Barros J. Chromatogr. A 1162 2007 103 113
21. P.A.J. Rosa, A.M. Azevedo, and M.R. Aires-Barros J. Chromatogr. A 1141 2007 50 60
22. P.A.J. Rosa, A.M. Azevedo, S. Sommerfeld, M. Mutter, M.R. Aires-Barros, and W. Bäcker J. Biotechnol. 139 4 2009 306 313
23. Sartorius Datasheet: Sartobind® Protein A 2 ml, 4 mm bed height 2010
24. ® Phenyl 3 ml, 150 ml, 5 l, 8 mm bed height 2011
25. ® Q and S SingleSep nano 1 ml, 4 mm bed height 2012
26. A. Straathof M. Moo-Young, Comprehensive Biotechnology 2nd ed. 2011 Academic Press Burlington 811 814
27. S. Sturesson, F. Tjerneld, and G. Johansson Appl. Biochem. Biotechnol. 26 1990 281 295
28. J. Thömmes, and M. Etzel Biotechnol. Prog. 23 2007 42 45
29. P. van Beijeren, P. Kreis, and T. Zeiner J. Membr. Sci. 415 2012 568 576
30. B.Y. Zaslavsky Anal. Chem. 64 1992 765A 773A
31. B.Y. Zaslavsky Aqueous Two-phase Partitioning: Physical Chemistry and Bioanalytical Applications 1995 M. Dekker New York