Severe vitamin D deficiency is associated with frequently observed diseases in medical inpatients

International Journal of Clinical Practice

Volumn 68, Issue 5, 2014, Pages 647-652

  Marra, A ^a   Leoncini, G ^a   Mussap, M ^b   Bovio, M ^a   Nazzari, E ^a   Giusti, M ^a   Minuto, F ^a   Murialdo, G ^a   Ameri, P ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; PARATHYROID HORMONE; 25-HYDROXYVITAMIN D; BIOLOGICAL MARKER; VITAMIN D;

AGE; AGED; ARTICLE; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; HEART FAILURE; HEPATITIS; HOSPITAL PATIENT; HUMAN; HYPERTENSION; INFECTION; LENGTH OF STAY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; VITAMIN D DEFICIENCY; ANALOGS AND DERIVATIVES; BLOOD; COMPLICATION; FEMALE; LIVER DISEASE; MALE; MIDDLE AGED; PROSPECTIVE STUDY; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

AGED; BIOMARKERS; CEREBROVASCULAR DISORDERS; FEMALE; HEART FAILURE; HUMANS; HYPERTENSION; INFECTION; INPATIENTS; LENGTH OF STAY; LIVER DISEASES; MALE; MIDDLE AGED; PARATHYROID HORMONE; PROSPECTIVE STUDIES; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84898943442     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/ijcp.12323     Document Type: Article

References (37)

1. Thomas MK, Lloyd-Jones DM, Thadhani RI, et al. Hypovitaminosis D in medical inpatients. N Engl J Med 1998; 338: 777-83.
2. Hochwald O, Harman-Boehm I, Castel H,. Hypovitaminosis D among inpatients in a sunny country. Isr Med Assoc J 2004; 6: 82-7.
3. Corino A, D'Amelio P, Gancia R,. et al., Hypovitaminosis D in internal medicine inpatients. Calcif Tissue Int 2007; 80: 76-80.
4. Moore NL, Kiebzak GM,. Suboptimal vitamin D status is a highly prevalent but treatable condition in both hospitalized patients and the general population. J Am Acad Nurse Pract 2007; 19: 642-51.
5. Lyman D,. Undiagnosed vitamin D deficiency in the hospitalized patient. Am Fam Physician 2005; 71: 299-304.
6. Kim DH, Sabour S, Sagar UN, Adams S, Whellan DJ,. Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004). Am J Cardiol 2008; 102: 1540-4.
7. Ginde AA, Mansbach JM, Camargo CA Jr,. Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med 2009; 169: 384-90.
8. Pilz S, März W, Wellnitz B, et al. Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography. J Clin Endocrinol Metab 2008; 93: 3927-35.
9. Ameri P, Ronco D, Casu M, et al. High prevalence of vitamin D deficiency and its association with left ventricular dilation: an echocardiography study in elderly patients with chronic heart failure. Nutr Metab Cardiovasc Dis 2010; 20: 633-40.
10. Remmelts HH, van de Garde EM, Meijvis SC, et al. Addition of vitamin D status to prognostic scores improves the prediction of outcome in community-acquired pneumonia. Clin Infect Dis 2012; 55: 1488-94.
11. Sorbi S, Hort J, Erkinjuntti T, et al. EFNS-ENS Guidelines on the diagnosis and management of disorders associated with dementia. Eur J Neurol 2012; 19: 1159-79.
12. Wagner D, Hanwell HE, Vieth R,. An evaluation of automated methods for measurement of serum 25-hydroxyvitamin D. Clin Biochem 2009; 42: 1549-56.
13. Inaba M, Nakatsuka K, Imanishi Y, et al. Technical and clinical characterization of the Bio-PTH (1-84) immunochemiluminometric assay and comparison with a second-generation assay for parathyroid hormone. Clin Chem 2004; 50: 385-90.
14. Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009; 150: 604-12.
15. Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011; 96: 1911-30.
16. Kestenbaum B, Katz R, de Boer I, et al. Vitamin D, parathyroid hormone, and cardiovascular events among older adults. J Am Coll Cardiol 2011; 58: 1433-41.
17. Anderson JL, Vanwoerkom RC, Horne BD, et al. Parathyroid hormone, vitamin D, renal dysfunction, and cardiovascular disease: dependent or independent risk factors? Am Heart J 2011; 162: 331-9.
18. Mastala Y, Nyangulu P, Banda RV, Mhemedi B, White SA, Allain TJ,. Vitamin D deficiency in medical patients at a central hospital in Malawi: a comparison with TB patients from a previous study. PLoS ONE 2013; 8: e59017.
19. Romagnoli E, Caravella P, Scarnecchia L, Martinez P, Minisola S,. Hypovitaminosis D in an Italian population of healthy subjects and hospitalized patients. Br J Nutr 1999; 81: 133-7.
20. Premaor MO, Alves GV, Crossetti LB, Furlanetto TW,. Hyperparathyroidism secondary to hypovitaminosis D in hypoalbuminemic is less intense than in normoalbuminemic patients: a prevalence study in medical inpatients in southern Brazil. Endocrine 2004; 24: 47-53.
21. Kauppinen-Mäkelin R, Tähtelä R, Löyttyniemi E, Kärkkäinen J, Välimäki MJ,. A high prevalence of hypovitaminosis D in Finnish medical in- and outpatients. J Intern Med 2001; 249: 559-63.
22. Boyages S, Bilinski K,. Seasonal reduction in vitamin D level persists into spring in NSW Australia: implications for monitoring and replacement therapy. Clin Endocrinol (Oxf) 2012; 77: 515-23.
23. Blicher TM, Jørgensen HL, Schwarz P, Wulf HC,. Low levels of vitamin D are associated with increased mortality in patients attending a university hospital in Denmark. Scand J Clin Lab Invest 2013; 73: 24-8.
24. Chatfield SM, Brand C, Ebeling PR, Russell DM,. Vitamin D deficiency in general medical inpatients in summer and winter. Intern Med J 2007; 37: 377-82.
25. Sutra Del Galy A, Bertrand M, Bigot F, et al. Vitamin D insufficiency and acute care in geriatric inpatients. J Am Geriatr Soc 2009; 57: 1721-3.
26. Annweiler C, Fantino B, Le Gall D, Schott AM, Berrut G, Beauchet O,. Severe vitamin D deficiency is associated with advanced-stage dementia in geriatric inpatients. J Am Geriatr Soc 2011; 59: 169-71.
27. Beauchet O, Hélard L, Montero-Odasso M, de Decker L, Berrut G, Annweiler C,. Hypovitaminosis D in geriatric inpatients: a marker of severity of chronic diseases. Aging Clin Exp Res 2012; 24: 188-92.
28. Annweiler C, Pochic S, Fantino B, et al. Serum vitamin D concentration and short-term mortality among geriatric inpatients in acute care settings. Adv Ther 2010; 27: 245-9.
29. Coutard A, Garlantézec R, Estivin S, Andro M, Gentric A,. Association of vitamin D deficiency and anemia in a hospitalized geriatric population: denutrition as a confounding factor. Ann Hematol 2013; 92: 615-9.
30. Lips P, Duong T, Oleksik A, et al. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. J Clin Endocrinol Metab 2001; 86: 1212-21.
31. Oudshoorn C, van der Cammen TJ, McMurdo ME, van Leeuwen JP, Colin EM,. Ageing and vitamin D deficiency: effects on calcium homeostasis and considerations for vitamin D supplementation. Br J Nutr 2009; 101: 1597-606.
32. Kitson MT, Roberts SK,. D-livering the message: the importance of vitamin D status in chronic liver disease. J Hepatol 2012; 57: 897-909.
33. Mateus-Hamdan L, Beauchet O, Bouvard B, Legrand E, Fantino B, Annweiler C,. High parathyroid hormone, but not low vitamin D concentrations, expose elderly inpatients to hypertension. Geriatr Gerontol Int 2013; 13: 783-91.
34. Lange N, Litonjua AA, Gibbons FK, Giovannucci E, Christopher KB,. Pre-hospital vitamin D concentration, mortality, and bloodstream infection in a hospitalized patient population. Am J Med 2013; 126: 640.e19-27.
35. Quraishi SA, Litonjua AA, Moromizato T, et al. Association between prehospital vitamin D status and hospital-acquired bloodstream infections. Am J Clin Nutr 2013; 98: 952-9.
36. Reid D, Toole BJ, Knox S, et al. The relation between acute changes in the systemic inflammatory response and plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty. Am J Clin Nutr 2011; 93: 1006-11.
37. Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006; 311: 1770-3.