Vitamin D deficiency in general medical inpatients in summer and winter

Internal Medicine Journal

Volumn 37, Issue 6, 2007, Pages 377-382

  Chatfield, S M ^a   Brand, C ^a   Ebeling, P R ^b   Russell, D M ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Aged; Inpatient; Vitamin D deficiency

Indexed keywords

25 HYDROXYVITAMIN D; ANTICONVULSIVE AGENT; CALCIUM; ERGOCALCIFEROL; PARATHYROID HORMONE; VITAMIN D;

ADULT; AGED; ARTICLE; CALCIUM BLOOD LEVEL; COMORBIDITY; CONTROLLED STUDY; DRUG USE; FALLING; FEMALE; FRACTURE; GENERAL PRACTICE; HORMONE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL SERVICE; PATIENT INFORMATION; PREVALENCE; PRIORITY JOURNAL; SUMMER; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; WINTER;

AGED; AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; FAMILY PRACTICE; FEMALE; HUMANS; INPATIENTS; MALE; MIDDLE AGED; SEASONS; SUNLIGHT; VITAMIN D DEFICIENCY;

EID: 34447105503     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2007.01339.x     Document Type: Article

References (31)

1. Pasco JA, Henry MJ, Nicholson GC, Sanders KM, Kotowicz MA. Vitamin D status of women in the Geelong Osteoporosis Study: association with diet and casual exposure to sunlight. Med J Aust 2001 175 : 401 5.
2. MacGrath JJ, Kimlin MG, Saha S, Eyles DW, Parisi AV. Vitamin D insufficiency in south-east Queensland. Med J Aust 2001 174 : 150 51.
3. Flicker L, Mead K, MacInnis RJ, Nowson C, Schere S, Stein M et al. Serum vitamin D and falls in older women in residential care in Australia. J Am Geriatr Soc 2003 51 : 1533 8.
4. Inderjeeth CA, Nicklason F, Al-Lahham Y, Greenaway TM, Jones G, Parameswaran VV et al. Vitamin D deficiency and secondary hyperparathyroidism: clinical and biochemical associations in older non-institutionalised Southern Tasmanians. Aust N Z J Med 2000 30 : 209 14.
5. Frame B, Parfitt AM. Osteomalacia: current concepts. Ann Intern Med 1978 89 : 966 82.
6. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Dawson-Hughes B. Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults. Am J Med 2004 116 : 634 9.
7. Chatfield S, Ebeling PR. Osteoporosis prevention and treatment: the importance of vitamin D. Mod Med 2005 6 : 16 32.
8. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S. Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med 1992 327 : 1637 42.
9. Dawson-Hughes B, Harris S, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 1997 337 : 670 76.
10. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY et al. Effect of Vitamin D on falls: a meta-analysis. JAMA 2004 291 : 1999 2006.
11. Thomas MK, Lloyd-Jones DM, Thadhani RI, Shaw AC, Deraska DJ, Kitch BT et al. Hypovitaminosis D in medical inpatients. N Engl J Med 1998 338 : 777 83.
12. Kauppinen-Makelin R, Tahtela R, Loyttyniemi E, Karkkainen J, Valimaki MJ. A high prevalence of hypovitaminosis D in Finnish medical in- and outpatients. J Intern Med 2001 249 : 559 63.
13. Hochwald O, Harman-Boehm I, Castel H. Hypovitaminosis D among inpatients in a sunny country. Isr Med Assoc J 2004 6 : 82 7.
14. Working Group of the Australian and New Zealand Bone and Mineral Society, Endocrine Society of Australia and Osteoporosis Australia. Vitamin D and adult bone health in Australia and New Zealand: a position statement. Med J Aust 2005 182 : 281 5.
15. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 2001 22 : 477 501.
16. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976 16 : 31 41.
17. Smith GR, Collinson PO, Kiely PD. Diagnosing hypovitaminosis D: serum measurements of calcium, phosphate, and alkaline phosphatase are unreliable, even in the presence of secondary hyperparathyroidism. J Rheumatol 2005 32 : 684 9.
18. Sambrook PN, Chen JS, March LM, Cameron ID, Cumming RG, Lord SR et al. Serum parathyroid hormone predicts time to fall independent of vitamin D status in a frail elderly population. J Clin Endocrinol Metab 2004 89 : 1572 6.
19. Sambrook PN, Chen JS, March LM, Cameron ID, Cumming RG, Lord SR et al. Serum parathyroid hormone is associated with increased mortality independent of 25-hydroxy vitamin D status, bone mass, and renal function in the frail and very old: a cohort study. J Clin Endocrinol Metab 2004 89 : 5477 81.
20. Zochling J, Chen JS, Seibel M, Schwarz J, Cameron ID, Cumming RG et al. Calcium metabolism in the frail elderly. Clin Rheumatol 2005 24 : 576 82.
21. Schoofs MW, van der Klift M, Hofman A, de Laet CE, Herings RM, Stijnen T et al. Thiazide diuretics and the risk for hip fracture. Ann Intern Med 2003 139 : 476 82.
22. Rejnmark L, Vestergaard P, Mosekilde L. Fracture risk in patients treated with loop diuretics. J Intern Med 2006 259 : 117 24.
23. Avenell A, Gillespie WJ, Gillespie LD, O'Connell DL. Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis. Cochrane Database Syst Rev 2005 3 : CD000227.
24. Grant AM, Avenell A, Campbell MK, McDonald AM, MacLennan GS, McPherson GC et al RECORD Trial Group. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or Vitamin D, RECORD): a randomised placebo-controlled trial. Lancet 2005 365 : 1621 8.
25. Porthouse J, Cockayne S, King C, Saxon L, Steele E, Aspray T et al. Randomised controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. BMJ 2005 330 : 1003.
26. Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE et al Women's Health Initiative Investigators. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med 2006 354 : 669 83.
27. Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA 2005 293 : 2257 64.
28. Bischoff-Ferrari HA, Orav EJ, Dawson-Hughes B. Effect of cholecalciferol plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trial. Arch Intern Med 2006 166 : 424 30.
29. Glendenning P, Taranto M, Noble JM, Musk AA, Hammond C, Goldswain PR et al. Current assays overestimate 25-hydroxyvitamin D3 and underestimate 25-hydroxyvitamin D2 compared with HPLC: need for assay-specific decision limits and metabolite-specific assays. Ann Clin Biochem 2006 43 (Pt 1 23 30.
30. Armas LAG, Hollis BW, Heaney RP. Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab 2004 89 : 5387 91.
31. Louw JA, Werbeck A, Louw MEJ, Kotze TJVW, Cooper R, Labadarios D. Blood vitamin concentrations during the acute-phase response. Crit Care Med 1992 20L : 934 41.