Association of vitamin D deficiency and anemia in a hospitalized geriatric population: Denutrition as a confounding factor

Annals of Hematology

Volumn 92, Issue 5, 2013, Pages 615-619

  Coutard, A ^a,b   Garlantezec R ^a,b   Estivin, S ^a,b   Andro, M ^a,b   Gentric, A ^a,b  

^a BREST UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

Author keywords

Anemia; Hypoalbuminemia; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; SERUM ALBUMIN; VITAMIN D;

AGED; ALBUMIN BLOOD LEVEL; ANEMIA; ARTICLE; DISEASE ASSOCIATION; FEMALE; FRANCE; GERIATRIC NUTRITION; HOSPITAL PATIENT; HUMAN; HYPOALBUMINEMIA; MAJOR CLINICAL STUDY; MALE; NUTRITIONAL DEFICIENCY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; WORLD HEALTH ORGANIZATION;

AGED; AGED, 80 AND OVER; ANEMIA; CONFOUNDING FACTORS (EPIDEMIOLOGY); ERYTHROPOIETIN; FEMALE; FRANCE; GERIATRICS; HEMOGLOBINS; HOSPITALIZATION; HUMANS; MALE; MALNUTRITION; PARATHYROID HORMONE; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84877920503     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-012-1633-9     Document Type: Article

References (33)

1. Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC (2004) Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood 104(8):2263-2268
2. Lechich A, Silverstone F, Finnigan S, Janowski MC, McCamish MA, Ershler WB et al (2004) Prevalence of anemia in skilled-nursing home residents. Arch Gerontol Geriatr 39(3):201-206
3. Landi F, Russo A, Danese P, Liperoti R, Barillaro C, Bernabei R et al (2007) Anemia status, hemoglobin concentration, and mortality in nursing home older residents. J Am Med Dir Assoc 8(5):322-327
4. Culleton BF, Manns BJ, Zhang J, Tonelli M, Klarenbach S, Hemmelgarn BR (2006) Impact of anemia on hospitalization and mortality in older adults. Blood 107(10):3841-3846
5. Dharmarajan TS, Norkus EP (2004) Mild anemia and the risk of falls in older adults from nursing homes and the community. J Am Med Dir Assoc 5(6):395-400
6. Penninx BWJH, Pluijm SMF, Lips P, Woodman R, Miedema K, Guralnik JM et al (2005) Late-life anemia is associated with increased risk of recurrent falls. J Am Geriatr Soc 53(12):2106-2111
7. Argyriadou S, Vlachonikolis I, Melisopoulou H, Katachanakis K, Lionis C (2001) In what extent anemia coexists with cognitive impairment in elderly: a cross-sectional study in Greece. BMC Fam Pract 2:5
8. Eisenstaedt R, Penninx BWJH, Woodman RC (2006) Anemia in the elderly: current understanding and emerging concepts. Blood Rev 20(4):213-226
9. Ross SD, Fahrbach K, Frame D, Scheye R, Connelly JE, Glaspy J (2003) The effect of anemia treatment on selected health-related quality-of-life domains: a systematic review. Clin Ther 25(6):1786-1805
10. Holick MF (2007) Vitamin D deficiency. N Engl J Med 357(3):266-281
11. Chapuy MC, Preziosi P, Maamer M, Arnaud S, Galan P, Hercberg S et al (1997) Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 7(5):439-443
12. Thomas MK, Lloyd-Jones DM, Thadhani RI, Shaw AC, Deraska DJ, Kitch BT et al (1998) Hypovitaminosis D in medical inpatients. N Engl J Med 338(12):777-783
13. McKenna MJ (1992) Differences in vitamin D status between countries in young adults and the elderly. Am J Med 93(1):69-77
14. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Hu FB, Zhang Y, Karlson EW et al (2004) Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged ≥60 y. Am J Clin Nutr 80(3):752-758
15. Bischoff HA, Stähelin HB, Dick W, Akos R, Knecht M, Salis C et al (2003) Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res 18(2):343-351
16. Ginde AA, Scragg R, Schwartz RS, Camargo CA (2009) Prospective study of serum 25-hydroxyvitamin D level, cardiovascular disease mortality, and all-cause mortality in older U.S. adults. J Am Geriatr Soc 57(9):1595-1603
17. Newmark HL, Giovannucci E, Wei M, Holick MF, Gorham ED, Garland CF et al (2007) Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev Med 32(3):210-216
18. Cantorna MT, Zhu Y, Froicu M, Wittke A (2004) Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr 80(6 Suppl):1717S-1720S
19. Aucella F, Scalzulli RP, Gatta G, Vigilante M, Carella AM, Stallone C (2003) Calcitriol increases burst-forming unit-erythroid proliferation in chronic renal failure. A synergistic effect with r-HuEpo. Nephron Clin Pract 95(4):c121-c127
20. Albitar S, Genin R, Fen-Chong M, Serveaux MO, Schohn D, Chuet C (1997) High-dose alfacalcidol improves anaemia in patients on haemodialysis. Nephrol Dial Transplant 12(3):514-518
21. Sim JJ, Lac PT, Liu ILA, Meguerditchian SO, Kumar VA, Kujubu DA et al (2010) Vitamin D deficiency and anemia: a cross-sectional study. Ann Hematol 89(5):447-452
22. Perlstein TS, Pande R, Berliner N, Vanasse GJ (2011) Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation. Blood 117(10):2800-2806
23. Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3):189-198
24. Groupe de Réflexion sur l'Évaluation Cognitive (GRECO) (1998) M.M.S.E.: Mini-Mental State Examination. Version française soumise à consensus (GRECO)
25. No authors listed (1968) Nutritional anaemias. Report of a WHO scientific group. World Health Organ Tech Rep Ser. 1968;405:5-37
26. Ble A, Fink JC, Woodman RC, Klausner MA, Windham BG, Guralnik JM et al (2005) Renal function, erythropoietin, and anemia of older persons: the InCHIANTI study. Arch Intern Med 165(19):2222-2227
27. Malabanan A, Veronikis IE, Holick MF (1998) Redefining vitamin D insufficiency. Lancet 351(9105):805-806
28. Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B (2006) Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 84(1):18-28
29. Artz AS (2008) Anemia and the frail elderly. Semin Hematol 45(4):261-266
30. Jemcov TK, Petakov M, Bogdanovic A, Djukanovic L, Lezaic VD (2008) Parathyroidectomy and improving anemia. Arch Surg 143(1):97-98
31. Zingraff J, Drüeke T, Marie P, Man NK, Jungers P, Bordier P (1978) Anemia and secondary hyperparathyroidism. Arch Intern Med 138(11):1650-1652
32. McCamish MA, Dai J, Keller E, Ershler WB, Artz AS, Fergusson D et al (2004) Mechanisms of unexplained anemia in the nursing home. J Am Geriatr Soc 52(3):423-427
33. Kario K, Matsuo T, Kodama K, Nakao K, Asada R (1992) Reduced erythropoietin secretion in senile anemia. Am J Hematol 41(4):252-257