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Volumn 75, Issue 9, 2014, Pages 701-710

Cognitive impairment and dentate gyrus synaptic dysfunction in experimental Parkinsonism

Author keywords

Dopamine D1 receptor; extracellular signal regulated kinases; hippocampus; long term potentiation; mouse; novel object recognition; Parkinson's disease

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALPHA [AMINO(4 AMINOPHENYLTHIO)METHYLENE] 2 (TRIFLUOROMETHYL)PHENYLACETONITRILE; BENSERAZIDE; CARBIDOPA; DESIPRAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; LEVODOPA; MITOGEN ACTIVATED PROTEIN KINASE; NORADRENALIN; OXIDOPAMINE; PRAMIPEXOLE;

EID: 84898919586     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.02.015     Document Type: Article
Times cited : (57)

References (50)
  • 1
  • 2
    • 0014082977 scopus 로고
    • Parkinsonism: Onset, progression and mortality
    • M.M. Hoehn, and M.D. Yahr Parkinsonism: Onset, progression and mortality Neurology 17 1967 427 442
    • (1967) Neurology , vol.17 , pp. 427-442
    • Hoehn, M.M.1    Yahr, M.D.2
  • 3
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: Clinical features and diagnosis
    • DOI 10.1136/jnnp.2007.131045
    • J. Jankovic Parkinson's disease: Clinical features and diagnosis J Neurol Neurosurg Psychiatry 79 2008 368 376 (Pubitemid 351441488)
    • (2008) Journal of Neurology, Neurosurgery and Psychiatry , vol.79 , Issue.4 , pp. 368-376
    • Jankovic, J.1
  • 5
    • 64349083816 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson's disease: Dopaminergic pathophysiology and treatment
    • K.R. Chaudhuri, and A.H. Schapira Non-motor symptoms of Parkinson's disease: Dopaminergic pathophysiology and treatment Lancet Neurol 8 2009 464 474
    • (2009) Lancet Neurol , vol.8 , pp. 464-474
    • Chaudhuri, K.R.1    Schapira, A.H.2
  • 6
    • 79955112282 scopus 로고    scopus 로고
    • A critical appraisal of the premotor symptoms of Parkinson's disease: Potential usefulness in early diagnosis and design of neuroprotective trials
    • A.E. Lang A critical appraisal of the premotor symptoms of Parkinson's disease: Potential usefulness in early diagnosis and design of neuroprotective trials Mov Disord 26 2011 775 783
    • (2011) Mov Disord , vol.26 , pp. 775-783
    • Lang, A.E.1
  • 7
    • 2042470821 scopus 로고    scopus 로고
    • Visual object recognition deficits in early Parkinson's disease
    • DOI 10.1016/j.parkreldis.2004.02.001, PII S1353802004000252
    • S. Laatu, A. Revonsuo, L. Pihko, R. Portin, and J.O. Rinne Visual object recognition deficits in early Parkinson's disease Parkinsonism Relat Disord 10 2004 227 233 (Pubitemid 38534616)
    • (2004) Parkinsonism and Related Disorders , vol.10 , Issue.4 , pp. 227-233
    • Laatu, S.1    Revonsuo, A.2    Pihko, L.3    Portin, R.4    Rinne, J.O.5
  • 8
    • 54049115942 scopus 로고    scopus 로고
    • Spatial and object working memory deficits in Parkinson's disease are due to impairment in different underlying processes
    • K.L. Possin, J.V. Filoteo, D.D. Song, and D.P. Salmon Spatial and object working memory deficits in Parkinson's disease are due to impairment in different underlying processes Neuropsychology 22 2008 585 595
    • (2008) Neuropsychology , vol.22 , pp. 585-595
    • Possin, K.L.1    Filoteo, J.V.2    Song, D.D.3    Salmon, D.P.4
  • 9
    • 0031060220 scopus 로고    scopus 로고
    • Cognitive deficits in Parkinson's disease
    • B. Dubois, and B. Pillon Cognitive deficits in Parkinson's disease J Neurol 244 1997 2 8 (Pubitemid 26413891)
    • (1997) Journal of Neurology , vol.244 , Issue.1 , pp. 2-8
    • Dubois, B.1    Pillon, B.2
  • 10
    • 0021969078 scopus 로고
    • Intellectual changes in patients with MPTP-induced parkinsonism
    • Y. Stern, and J.W. Langston Intellectual changes in patients with MPTP-induced parkinsonism Neurology 35 1985 1506 1509 (Pubitemid 15242435)
    • (1985) Neurology , vol.35 , Issue.10 , pp. 1506-1509
    • Stern, Y.1    Langston, J.W.2
  • 11
    • 79953318386 scopus 로고    scopus 로고
    • The intranasal administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP): A new rodent model to test palliative and neuroprotective agents for Parkinson's disease
    • R.D. Prediger, A.S. Aguiar Jr, E.L. Moreira, F.C. Matheus, A.A. Castro, and R. Walz The intranasal administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP): A new rodent model to test palliative and neuroprotective agents for Parkinson's disease Curr Pharm Des 17 2011 489 507
    • (2011) Curr Pharm des , vol.17 , pp. 489-507
    • Prediger, R.D.1    Aguiar, Jr.A.S.2    Moreira, E.L.3    Matheus, F.C.4    Castro, A.A.5    Walz, R.6
  • 12
    • 67650410009 scopus 로고    scopus 로고
    • Distinct hippocampal and basal ganglia contributions to probabilistic learning and reversal
    • D. Shohamy, C.E. Myers, R.O. Hopkins, J. Sage, and M.A. Gluck Distinct hippocampal and basal ganglia contributions to probabilistic learning and reversal J Cogn Neurosci 21 2009 1821 1833
    • (2009) J Cogn Neurosci , vol.21 , pp. 1821-1833
    • Shohamy, D.1    Myers, C.E.2    Hopkins, R.O.3    Sage, J.4    Gluck, M.A.5
  • 13
    • 0029116316 scopus 로고
    • Modulation of memory fields by dopamine D1 receptors in prefrontal cortex
    • G.V. Williams, and P.S. Goldman-Rakic Modulation of memory fields by dopamine D1 receptors in prefrontal cortex Nature 376 1995 572 575
    • (1995) Nature , vol.376 , pp. 572-575
    • Williams, G.V.1    Goldman-Rakic, P.S.2
  • 14
    • 1942454250 scopus 로고    scopus 로고
    • Inflammation and neurodegeneration in Parkinson's disease
    • P.L. McGeer, and E.G. McGeer Inflammation and neurodegeneration in Parkinson's disease Parkinsonism Relat Disord 10 suppl 1 2004 S3 S7
    • (2004) Parkinsonism Relat Disord , vol.10 , Issue.SUPPL. 1
    • McGeer, P.L.1    McGeer, E.G.2
  • 15
    • 0025923293 scopus 로고
    • The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro
    • U. Frey, H. Matthies, K.G. Reymann, and H. Matthies The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro Neurosci Lett 129 1991 111 114
    • (1991) Neurosci Lett , vol.129 , pp. 111-114
    • Frey, U.1    Matthies, H.2    Reymann, K.G.3    Matthies, H.4
  • 17
    • 0030834098 scopus 로고    scopus 로고
    • Dopaminergic modulation of LTP induction in the dentate gyrus of intact brain
    • T. Kusuki, Y. Imahori, S. Ueda, and K. Inokuchi Dopaminergic modulation of LTP induction in the dentate gyrus of intact brain NeuroReport 8 1997 2037 2040 (Pubitemid 27314330)
    • (1997) NeuroReport , vol.8 , Issue.8 , pp. 2037-2040
    • Kusuki, T.1    Imahori, Y.2    Ueda, S.3    Inokuchi, K.4
  • 18
    • 69949100707 scopus 로고    scopus 로고
    • Dopamine enables in vivo synaptic plasticity associated with the addictive drug nicotine
    • J. Tang, and J.A. Dani Dopamine enables in vivo synaptic plasticity associated with the addictive drug nicotine Neuron 63 2009 673 682
    • (2009) Neuron , vol.63 , pp. 673-682
    • Tang, J.1    Dani, J.A.2
  • 19
    • 36849076744 scopus 로고    scopus 로고
    • 5 dopamine receptors are critical for LTP, spatial learning, and LTP-induced arc and zif268 expression in the hippocampus
    • DOI 10.1093/cercor/bhm026
    • N. Granado, O. Ortiz, L.M. Suarez, E.D. Martin, V. Cena, and J.M. Solis D1 but not D5 dopamine receptors are critical for LTP, spatial learning, and LTP-Induced arc and zif268 expression in the hippocampus Cereb Cortex 18 2008 1 12 (Pubitemid 350233047)
    • (2008) Cerebral Cortex , vol.18 , Issue.1 , pp. 1-12
    • Granado, N.1    Ortiz, O.2    Suarez, L.M.3    Martin, E.D.4    Cena, V.5    Solis, J.M.6    Moratalla, R.7
  • 20
    • 33747066441 scopus 로고    scopus 로고
    • 5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression
    • DOI 10.1523/JNEUROSCI.1454-06.2006
    • N. Lemon, and D. Manahan-Vaughan Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression J Neurosci 26 2006 7723 7729 (Pubitemid 44315192)
    • (2006) Journal of Neuroscience , vol.26 , Issue.29 , pp. 7723-7729
    • Lemon, N.1    Manahan-Vaughan, D.2
  • 21
    • 77956794197 scopus 로고    scopus 로고
    • Associative learning and CA3-CA1 synaptic plasticity are impaired in D1R null, Drd1a-/- mice and in hippocampal siRNA silenced Drd1a mice
    • O. Ortiz, J.M. Delgado-Garcia, I. Espadas, A. Bahi, R. Trullas, and J.L. Dreyer Associative learning and CA3-CA1 synaptic plasticity are impaired in D1R null, Drd1a-/- mice and in hippocampal siRNA silenced Drd1a mice J Neurosci 30 2010 12288 12300
    • (2010) J Neurosci , vol.30 , pp. 12288-12300
    • Ortiz, O.1    Delgado-Garcia, J.M.2    Espadas, I.3    Bahi, A.4    Trullas, R.5    Dreyer, J.L.6
  • 22
    • 0029997176 scopus 로고    scopus 로고
    • D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses
    • N.A. Otmakhova, and J.E. Lisman D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses J Neurosci 16 1996 7478 7486 (Pubitemid 26389686)
    • (1996) Journal of Neuroscience , vol.16 , Issue.23 , pp. 7478-7486
    • Otmakhova, N.A.1    Lisman, J.E.2
  • 24
    • 77955416245 scopus 로고    scopus 로고
    • Dopamine D1 but not D3 receptor is critical for spatial learning and related signaling in the hippocampus
    • B. Xing, H. Kong, X. Meng, S.G. Wei, M. Xu, and S.B. Li Dopamine D1 but not D3 receptor is critical for spatial learning and related signaling in the hippocampus Neuroscience 169 2010 1511 1519
    • (2010) Neuroscience , vol.169 , pp. 1511-1519
    • Xing, B.1    Kong, H.2    Meng, X.3    Wei, S.G.4    Xu, M.5    Li, S.B.6
  • 25
    • 58149328474 scopus 로고    scopus 로고
    • The immediate early gene arc/arg3.1: Regulation, mechanisms, and function
    • C.R. Bramham, P.F. Worley, M.J. Moore, and J.F. Guzowski The immediate early gene arc/arg3.1: Regulation, mechanisms, and function J Neurosci 28 2008 11760 11767
    • (2008) J Neurosci , vol.28 , pp. 11760-11767
    • Bramham, C.R.1    Worley, P.F.2    Moore, M.J.3    Guzowski, J.F.4
  • 26
    • 0038277408 scopus 로고    scopus 로고
    • How necessary is the activation of the immediate early gene zif 268 in synaptic plasticity and learning?
    • DOI 10.1016/S0166-4328(02)00421-7
    • S. Davis, B. Bozon, and S. Laroche How necessary is the activation of the immediate early gene zif268 in synaptic plasticity and learning? Behav Brain Res 142 2003 17 30 (Pubitemid 36677587)
    • (2003) Behavioural Brain Research , vol.142 , Issue.1-2 , pp. 17-30
    • Davis, S.1    Bozon, B.2    Laroche, S.3
  • 27
    • 0348143169 scopus 로고    scopus 로고
    • Chromatin remodeling and neuronal response: Multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons
    • DOI 10.1242/jcs.00804
    • C. Crosio, E. Heitz, C.D. Allis, E. Borrelli, and P. Sassone-Corsi Chromatin remodeling and neuronal response: Multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons J Cell Sci 116 2003 4905 4914 (Pubitemid 38016697)
    • (2003) Journal of Cell Science , vol.116 , Issue.24 , pp. 4905-4914
    • Crosio, C.1    Heitz, E.2    Allis, C.D.3    Borrelli, E.4    Sassone-Corsi, P.5
  • 28
    • 79955778377 scopus 로고    scopus 로고
    • Convulsant doses of a dopamine D1 receptor agonist result in Erk-dependent increases in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus
    • G. Gangarossa, M. Di Benedetto, G.J. O'Sullivan, M. Dunleavy, C. Alcacer, and A. Bonito-Oliva Convulsant doses of a dopamine D1 receptor agonist result in Erk-dependent increases in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus PLoS One 6 2011 e19415
    • (2011) PLoS One , vol.6 , pp. 19415
    • Gangarossa, G.1    Di Benedetto, M.2    O'Sullivan, G.J.3    Dunleavy, M.4    Alcacer, C.5    Bonito-Oliva, A.6
  • 29
    • 0034660615 scopus 로고    scopus 로고
    • The MAPK/ERK cascade targets both Elk-1 and cAMP response element- binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo
    • S. Davis, P. Vanhoutte, C. Pages, J. Caboche, and S. Laroche The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo J Neurosci 20 2000 4563 4572 (Pubitemid 30396622)
    • (2000) Journal of Neuroscience , vol.20 , Issue.12 , pp. 4563-4572
    • Davis, S.1    Vanhoutte, P.2    Pages, C.3    Caboche, J.4    Laroche, S.5
  • 30
    • 0030749510 scopus 로고    scopus 로고
    • A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation
    • DOI 10.1074/jbc.272.31.19103
    • J.D. English, and J.D. Sweatt A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation J Biol Chem 272 1997 19103 19106 (Pubitemid 27337694)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.31 , pp. 19103-19106
    • English, J.D.1    Sweatt, J.D.2
  • 31
    • 39849098174 scopus 로고    scopus 로고
    • Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampus
    • DOI 10.1523/JNEUROSCI.3711-07.2008
    • C. Goeldner, D. Reiss, J. Wichmann, H. Meziane, B.L. Kieffer, and A.M. Ouagazzal Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampus J Neurosci 28 2008 2190 2198 (Pubitemid 351317630)
    • (2008) Journal of Neuroscience , vol.28 , Issue.9 , pp. 2190-2198
    • Goeldner, C.1    Reiss, D.2    Wichmann, J.3    Meziane, H.4    Kieffer, B.L.5    Ouagazzal, A.-M.6
  • 32
    • 0038113070 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase in hippocampal circuitry is required for consolidation and reconsolidation of recognition memory
    • A. Kelly, S. Laroche, and S. Davis Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase in hippocampal circuitry is required for consolidation and reconsolidation of recognition memory J Neurosci 23 2003 5354 5360 (Pubitemid 36793264)
    • (2003) Journal of Neuroscience , vol.23 , Issue.12 , pp. 5354-5360
    • Kelly, A.1    Laroche, S.2    Davis, S.3
  • 34
    • 34347215149 scopus 로고    scopus 로고
    • Object recognition in rats and mice: A one-trial non-matching-to-sample learning task to study 'recognition memory'
    • R.A. Bevins, and J. Besheer Object recognition in rats and mice: A one-trial non-matching-to-sample learning task to study 'recognition memory' Nat Protoc 1 2006 1306 1311
    • (2006) Nat Protoc , vol.1 , pp. 1306-1311
    • Bevins, R.A.1    Besheer, J.2
  • 35
    • 0022259894 scopus 로고
    • Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices
    • P.K. Stanton, and J.M. Sarvey Depletion of norepinephrine, but not serotonin, reduces long-term potentiation in the dentate gyrus of rat hippocampal slices J Neurosci 5 1985 2169 2176 (Pubitemid 15010998)
    • (1985) Journal of Neuroscience , vol.5 , Issue.8 , pp. 2169-2176
    • Stanton, P.K.1    Sarvey, J.M.2
  • 36
    • 0034554854 scopus 로고    scopus 로고
    • Impaired recognition memory in rats after damage to the hippocampus
    • R.E. Clark, S.M. Zola, and L.R. Squire Impaired recognition memory in rats after damage to the hippocampus J Neurosci 20 2000 8853 8860
    • (2000) J Neurosci , vol.20 , pp. 8853-8860
    • Clark, R.E.1    Zola, S.M.2    Squire, L.R.3
  • 37
    • 33746496228 scopus 로고    scopus 로고
    • Temporary inactivation reveals an essential role of the dorsal hippocampus in consolidation of object recognition memory
    • DOI 10.1016/j.neulet.2006.06.044, PII S0304394006006343
    • de M.N. Lima, T. Luft, R. Roesler, and N. Schroder Temporary inactivation reveals an essential role of the dorsal hippocampus in consolidation of object recognition memory Neurosci Lett 405 2006 142 146 (Pubitemid 44142833)
    • (2006) Neuroscience Letters , vol.405 , Issue.1-2 , pp. 142-146
    • De Lima, M.N.1    Luft, T.2    Roesler, R.3    Schroder, N.4
  • 38
    • 73349138565 scopus 로고    scopus 로고
    • Ontogeny of rat recognition memory measured by the novel object recognition task
    • M.L. Reger, D.A. Hovda, and C.C. Giza Ontogeny of rat recognition memory measured by the novel object recognition task Dev Psychobiol 51 2009 672 678
    • (2009) Dev Psychobiol , vol.51 , pp. 672-678
    • Reger, M.L.1    Hovda, D.A.2    Giza, C.C.3
  • 39
    • 0030004460 scopus 로고    scopus 로고
    • The hippocampus and long-term object memory in the rat
    • N. Vnek, and L.A. Rothblat The hippocampus and long-term object memory in the rat J Neurosci 16 1996 2780 2787 (Pubitemid 26122692)
    • (1996) Journal of Neuroscience , vol.16 , Issue.8 , pp. 2780-2787
    • Vnek, N.1    Rothblat, L.A.2
  • 40
    • 2942555108 scopus 로고    scopus 로고
    • On the delay-dependent involvement of the hippocampus in object recognition memory
    • DOI 10.1016/j.nlm.2004.03.005, PII S1074742704000449
    • R.S. Hammond, L.E. Tull, and R.W. Stackman On the delay-dependent involvement of the hippocampus in object recognition memory Neurobiol Learn Mem 82 2004 26 34 (Pubitemid 38737427)
    • (2004) Neurobiology of Learning and Memory , vol.82 , Issue.1 , pp. 26-34
    • Hammond, R.S.1    Tull, L.E.2    Stackman, R.W.3
  • 41
    • 58149462237 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease
    • E. De Leonibus, F. Manago, F. Giordani, F. Petrosino, S. Lopez, and A. Oliverio Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease Neuropsychopharmacology 34 2009 729 738
    • (2009) Neuropsychopharmacology , vol.34 , pp. 729-738
    • De Leonibus, E.1    Manago, F.2    Giordani, F.3    Petrosino, F.4    Lopez, S.5    Oliverio, A.6
  • 42
    • 84861536116 scopus 로고    scopus 로고
    • Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease
    • C. Costa, C. Sgobio, S. Siliquini, A. Tozzi, M. Tantucci, and V. Ghiglieri Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease Brain 135 2012 1884 1899
    • (2012) Brain , vol.135 , pp. 1884-1899
    • Costa, C.1    Sgobio, C.2    Siliquini, S.3    Tozzi, A.4    Tantucci, M.5    Ghiglieri, V.6
  • 43
    • 0034995459 scopus 로고    scopus 로고
    • Effects of adult neurogenesis on synaptic plasticity in the rat dentate gyrus
    • J.S. Snyder, N. Kee, and J.M. Wojtowicz Effects of adult neurogenesis on synaptic plasticity in the rat dentate gyrus J Neurophysiol 85 2001 2423 2431 (Pubitemid 32525520)
    • (2001) Journal of Neurophysiology , vol.85 , Issue.6 , pp. 2423-2431
    • Snyder, J.S.1    Kee, N.2    Wojtowicz, J.M.3
  • 44
    • 0026611856 scopus 로고
    • A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques
    • A. Mansour, J.H. Meador-Woodruff, Q. Zhou, O. Civelli, H. Akil, and S.J. Watson A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques Neuroscience 46 1992 959 971
    • (1992) Neuroscience , vol.46 , pp. 959-971
    • Mansour, A.1    Meador-Woodruff, J.H.2    Zhou, Q.3    Civelli, O.4    Akil, H.5    Watson, S.J.6
  • 45
    • 84898848660 scopus 로고    scopus 로고
    • Revisiting the effects of Parkinson's disease and frontal lobe lesions on task switching: The role of rule reconfiguration [published online ahead of print December 20]
    • A.A. Kehagia, R.A. Barker, and T.W. Robbins Revisiting the effects of Parkinson's disease and frontal lobe lesions on task switching: The role of rule reconfiguration [published online ahead of print December 20] J Neuropsychol. 2012
    • (2012) J Neuropsychol.
    • Kehagia, A.A.1    Barker, R.A.2    Robbins, T.W.3
  • 46
    • 0037705985 scopus 로고    scopus 로고
    • Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry
    • S.J. Lewis, A. Dove, T.W. Robbins, R.A. Barker, and A.M. Owen Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry J Neurosci 23 2003 6351 6356 (Pubitemid 36875637)
    • (2003) Journal of Neuroscience , vol.23 , Issue.15 , pp. 6351-6356
    • Lewis, S.J.G.1    Dove, A.2    Robbins, T.W.3    Barker, R.A.4    Owen, A.M.5
  • 47
    • 13844275931 scopus 로고    scopus 로고
    • Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease
    • DOI 10.1016/j.neuropsychologia.2004.10.001
    • S.J. Lewis, A. Slabosz, T.W. Robbins, R.A. Barker, and A.M. Owen Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease Neuropsychologia 43 2005 823 832 (Pubitemid 40248892)
    • (2005) Neuropsychologia , vol.43 , Issue.6 , pp. 823-832
    • Lewis, S.J.G.1    Slabosz, A.2    Robbins, T.W.3    Barker, R.A.4    Owen, A.M.5
  • 48
    • 84881569134 scopus 로고    scopus 로고
    • Levodopa improves motor deficits but can further disrupt cognition in a macaque parkinson model [published online ahead of print December 12]
    • J.S. Schneider, E.Y. Pioli, Y. Jianzhong, Q. Li, and E. Bezard Levodopa improves motor deficits but can further disrupt cognition in a macaque parkinson model [published online ahead of print December 12] Mov Disord. 2012
    • (2012) Mov Disord.
    • Schneider, J.S.1    Pioli, E.Y.2    Jianzhong, Y.3    Li, Q.4    Bezard, E.5
  • 49
    • 77957830241 scopus 로고    scopus 로고
    • Dopamine receptor agonists for the treatment of early or advanced Parkinson's disease
    • S. Perez-Lloret, and O. Rascol Dopamine receptor agonists for the treatment of early or advanced Parkinson's disease CNS Drugs 24 2010 941 968
    • (2010) CNS Drugs , vol.24 , pp. 941-968
    • Perez-Lloret, S.1    Rascol, O.2
  • 50
    • 61949226675 scopus 로고    scopus 로고
    • Treatments for Parkinson disease - Past achievements and current clinical needs
    • W. Poewe Treatments for Parkinson disease - past achievements and current clinical needs Neurology 72 2009 S65 S73
    • (2009) Neurology , vol.72
    • Poewe, W.1


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