메뉴 건너뛰기




Volumn 135, Issue 6, 2012, Pages 1884-1899

Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease

Author keywords

CA1 area; dementia; dopamine; glutamate; synaptic plasticity; synuclein

Indexed keywords

ALPHA SYNUCLEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 5 RECEPTOR; LEVODOPA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

EID: 84861536116     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aws101     Document Type: Article
Times cited : (130)

References (59)
  • 1
    • 0037174635 scopus 로고    scopus 로고
    • Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
    • Aarts M, Liu Y, Liu L, Besshoh S, Arundine M, Gurd JW, et al. Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions. Science 2002; 298: 846-50.
    • (2002) Science , vol.298 , pp. 846-850
    • Aarts, M.1    Liu, Y.2    Liu, L.3    Besshoh, S.4    Arundine, M.5    Gurd, J.W.6
  • 2
    • 33845886090 scopus 로고    scopus 로고
    • Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus
    • Bartlett TE, Bannister NJ, Collett VJ, Dargan SL, Massey PV, Bortolotto ZA, et al. Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus. Neuropharmacology 2007; 52: 60-70.
    • (2007) Neuropharmacology , vol.52 , pp. 60-70
    • Bartlett, T.E.1    Bannister, N.J.2    Collett, V.J.3    Dargan, S.L.4    Massey, P.V.5    Bortolotto, Z.A.6
  • 3
    • 34548218356 scopus 로고    scopus 로고
    • Rapid bidirectional switching of synaptic NMDA receptors
    • Bellone C, Nicoll RA. Rapid bidirectional switching of synaptic NMDA receptors. Neuron 2007; 55: 779-85.
    • (2007) Neuron , vol.55 , pp. 779-785
    • Bellone, C.1    Nicoll, R.A.2
  • 4
    • 43849090633 scopus 로고    scopus 로고
    • Age and dementia-associated atrophy predominates in the hippocampal head and amygdala in Parkinson's disease
    • Bouchard TP, Malykhin N, Martin WR, Hanstock CC, Emery DJ, Fisher NJ, et al. Age and dementia-associated atrophy predominates in the hippocampal head and amygdala in Parkinson's disease. Neurobiol Aging 2008; 29: 1027-39.
    • (2008) Neurobiol Aging , vol.29 , pp. 1027-1039
    • Bouchard, T.P.1    Malykhin, N.2    Martin, W.R.3    Hanstock, C.C.4    Emery, D.J.5    Fisher, N.J.6
  • 5
    • 4644277646 scopus 로고    scopus 로고
    • Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment
    • Bruck A, Kurki T, Kaasinen V, Vahlberg T, Rinne JO. Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment. J Neurol Neurosurg Psychiatry 2004; 75: 1467-9.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 1467-1469
    • Bruck, A.1    Kurki, T.2    Kaasinen, V.3    Vahlberg, T.4    Rinne, J.O.5
  • 6
    • 60149088953 scopus 로고    scopus 로고
    • Synaptic plasticity, dopamine and Parkinson's disease: One step ahead
    • Calabresi P, Mercuri NB, Di Filippo M. Synaptic plasticity, dopamine and Parkinson's disease: one step ahead. Brain 2009; 132: 285-7.
    • (2009) Brain , vol.132 , pp. 285-287
    • Calabresi, P.1    Mercuri, N.B.2    Di Filippo, M.3
  • 7
    • 33749672231 scopus 로고    scopus 로고
    • A convergent model for cognitive dysfunctions in Parkinson's disease: The critical dopamine-acetylcholine synaptic balance
    • Calabresi P, Picconi B, Parnetti L, Di Filippo M. A convergent model for cognitive dysfunctions in Parkinson's disease: the critical dopamine- acetylcholine synaptic balance. Lancet Neurol 2006; 5: 974-83.
    • (2006) Lancet Neurol , vol.5 , pp. 974-983
    • Calabresi, P.1    Picconi, B.2    Parnetti, L.3    Di Filippo, M.4
  • 8
    • 34247469023 scopus 로고    scopus 로고
    • Dopamine-mediated regulation of corticostriatal synaptic plasticity
    • Calabresi P, Picconi B, Tozzi A, Di Filippo M. Dopamine-mediated regulation of corticostriatal synaptic plasticity. Trends Neurosci 2007; 30: 211-9.
    • (2007) Trends Neurosci , vol.30 , pp. 211-219
    • Calabresi, P.1    Picconi, B.2    Tozzi, A.3    Di Filippo, M.4
  • 10
    • 0036583275 scopus 로고    scopus 로고
    • A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat
    • Clayton DA, Mesches MH, Alvarez E, Bickford PC, Browning MD. A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J Neurosci 2002; 22: 3628-37.
    • (2002) J Neurosci , vol.22 , pp. 3628-3637
    • Clayton, D.A.1    Mesches, M.H.2    Alvarez, E.3    Bickford, P.C.4    Browning, M.D.5
  • 11
    • 0035211233 scopus 로고    scopus 로고
    • Mechanisms of cognitive set flexibility in Parkinson's disease
    • Cools R, Barker RA, Sahakian BJ, Robbins TW. Mechanisms of cognitive set flexibility in Parkinson's disease. Brain 2001; 124: 2503-12.
    • (2001) Brain , vol.124 , pp. 2503-2512
    • Cools, R.1    Barker, R.A.2    Sahakian, B.J.3    Robbins, T.W.4
  • 12
    • 0032816549 scopus 로고    scopus 로고
    • The substantia nigra of the human brain.II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
    • Damier P, Hirsch EC, Agid Y, Graybiel AM. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain 1999; 122 (Pt 8): 1437-48.
    • (1999) Brain , vol.122 , Issue.PART 8 , pp. 1437-1448
    • Damier, P.1    Hirsch, E.C.2    Agid, Y.3    Graybiel, A.M.4
  • 13
    • 77953666105 scopus 로고    scopus 로고
    • Genetic animal models of Parkinson's disease
    • Dawson TM, Ko HS, Dawson VL. Genetic animal models of Parkinson's disease. Neuron 2010; 66: 646-61.
    • (2010) Neuron , vol.66 , pp. 646-661
    • Dawson, T.M.1    Ko, H.S.2    Dawson, V.L.3
  • 15
    • 0025923293 scopus 로고
    • The effect of dopamin-ergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro
    • Frey U, Matthies H, Reymann KG, Matthies H. The effect of dopamin-ergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro. Neurosci Lett 1991; 129: 111-4.
    • (1991) Neurosci Lett , vol.129 , pp. 111-114
    • Frey, U.1    Matthies, H.2    Reymann, K.G.3    Matthies, H.4
  • 16
    • 77954379317 scopus 로고    scopus 로고
    • SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease
    • Garcia-Reitbock P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, et al. SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. Brain 2010; 133: 2032-44.
    • (2010) Brain , vol.133 , pp. 2032-2044
    • Garcia-Reitbock, P.1    Anichtchik, O.2    Bellucci, A.3    Iovino, M.4    Ballini, C.5    Fineberg, E.6
  • 17
    • 58849120098 scopus 로고    scopus 로고
    • Decreased NR2B subunit synaptic levels cause impaired long-term potentiation but not long-term depression
    • Gardoni F, Mauceri D, Malinverno M, Polli F, Costa C, Tozzi A, et al. Decreased NR2B subunit synaptic levels cause impaired long-term potentiation but not long-term depression. J Neurosci 2009; 29: 669-77.
    • (2009) J Neurosci , vol.29 , pp. 669-677
    • Gardoni, F.1    Mauceri, D.2    Malinverno, M.3    Polli, F.4    Costa, C.5    Tozzi, A.6
  • 19
    • 0141446193 scopus 로고    scopus 로고
    • Altered glucocorticoid rhythm attenuates the ability of a chronic SSRI to elevate forebrain 5-HT: Implications for the treatment of depression
    • Gartside SE, Leitch MM, Young AH. Altered glucocorticoid rhythm attenuates the ability of a chronic SSRI to elevate forebrain 5-HT: implications for the treatment of depression. Neuropsychopharmacology 2003; 28: 1572-8.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1572-1578
    • Gartside, S.E.1    Leitch, M.M.2    Young, A.H.3
  • 21
    • 0024434128 scopus 로고
    • Midbrain dopaminergic cell loss in Parkinson's disease: Computer visualization
    • German DC, Manaye K, Smith WK, Woodward DJ, Saper CB. Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Ann Neurol 1989; 26: 507-14.
    • (1989) Ann Neurol , vol.26 , pp. 507-514
    • German, D.C.1    Manaye, K.2    Smith, W.K.3    Woodward, D.J.4    Saper, C.B.5
  • 22
    • 58349105525 scopus 로고    scopus 로고
    • Parkinson's disease dementia: Definitions, guidelines, and research perspectives in diagnosis
    • Goetz CG, Emre M, Dubois B. Parkinson's disease dementia: definitions, guidelines, and research perspectives in diagnosis. Ann Neurol 2008; 64 (Suppl 2): S81-92.
    • (2008) Ann Neurol , vol.64 , Issue.SUPPL. 2
    • Goetz, C.G.1    Emre, M.2    Dubois, B.3
  • 23
    • 36849076744 scopus 로고    scopus 로고
    • D1 but not D5 dopamine receptors are critical for LTP, spatial learning, and LTP-Induced arc and zif268 expression in the hippocampus
    • Granado N, Ortiz O, Suarez LM, Martin ED, Cena V, Solis JM, et al. D1 but not D5 dopamine receptors are critical for LTP, spatial learning, and LTP-Induced arc and zif268 expression in the hippocampus. Cereb Cortex 2008; 18: 1-12.
    • (2008) Cereb Cortex , vol.18 , pp. 1-12
    • Granado, N.1    Ortiz, O.2    Suarez, L.M.3    Martin, E.D.4    Cena, V.5    Solis, J.M.6
  • 24
    • 62949117379 scopus 로고    scopus 로고
    • Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus
    • Gureviciene I, Gurevicius K, Tanila H. Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus. J Neural Transm 2009; 116: 13-22.
    • (2009) J Neural Transm , vol.116 , pp. 13-22
    • Gureviciene, I.1    Gurevicius, K.2    Tanila, H.3
  • 25
  • 26
    • 0030757872 scopus 로고    scopus 로고
    • Burst activity of ventral tegmental dopamine neurons is elicited by sensory stimuli in the awake cat
    • Horvitz JC, Stewart T, Jacobs BL. Burst activity of ventral tegmental dopamine neurons is elicited by sensory stimuli in the awake cat. Brain Res 1997; 759: 251-8.
    • (1997) Brain Res , vol.759 , pp. 251-258
    • Horvitz, J.C.1    Stewart, T.2    Jacobs, B.L.3
  • 27
    • 0028931741 scopus 로고
    • D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus
    • Huang YY, Kandel ER. D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus. Proc Natl Acad Sci USA 1995; 92: 2446-50.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2446-2450
    • Huang, Y.Y.1    Kandel, E.R.2
  • 28
  • 29
    • 0442276505 scopus 로고    scopus 로고
    • Novel spatial arrangements of familiar visual stimuli promote activity in the rat hip-pocampal formation but not the parahippocampal cortices: A c-fos expression study
    • Jenkins TA, Amin E, Pearce JM, Brown MW, Aggleton JP. Novel spatial arrangements of familiar visual stimuli promote activity in the rat hip-pocampal formation but not the parahippocampal cortices: a c-fos expression study. Neuroscience 2004; 124: 43-52.
    • (2004) Neuroscience , vol.124 , pp. 43-52
    • Jenkins, T.A.1    Amin, E.2    Pearce, J.M.3    Brown, M.W.4    Aggleton, J.P.5
  • 30
    • 33750440495 scopus 로고    scopus 로고
    • Hippocampal neuron and glial cell numbers in Parkinson's disease: A stereological study
    • Joelving FC, Billeskov R, Christensen JR, West M, Pakkenberg B. Hippocampal neuron and glial cell numbers in Parkinson's disease: a stereological study. Hippocampus 2006; 16: 826-33.
    • (2006) Hippocampus , vol.16 , pp. 826-833
    • Joelving, F.C.1    Billeskov, R.2    Christensen, J.R.3    West, M.4    Pakkenberg, B.5
  • 31
    • 58349104581 scopus 로고    scopus 로고
    • Impaired cognitive performance in Parkinson's disease is related to caudate dopaminergic hypofunction and hippocampal atrophy
    • Jokinen P, Bruck A, Aalto S, Forsback S, Parkkola R, Rinne JO. Impaired cognitive performance in Parkinson's disease is related to caudate dopaminergic hypofunction and hippocampal atrophy. Parkinsonism Relat Disord 2009; 15: 88-93.
    • (2009) Parkinsonism Relat Disord , vol.15 , pp. 88-93
    • Jokinen, P.1    Bruck, A.2    Aalto, S.3    Forsback, S.4    Parkkola, R.5    Rinne, J.O.6
  • 32
    • 40849097599 scopus 로고    scopus 로고
    • The hippocampal CA1 region and dentate gyrus differentiate between environmental and spatial feature encoding through long-term depression
    • Kemp A, Manahan-Vaughan D. The hippocampal CA1 region and dentate gyrus differentiate between environmental and spatial feature encoding through long-term depression. Cereb Cortex 2008; 18: 968-77.
    • (2008) Cereb Cortex , vol.18 , pp. 968-977
    • Kemp, A.1    Manahan-Vaughan, D.2
  • 33
    • 33747066441 scopus 로고    scopus 로고
    • Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression
    • Lemon N, Manahan-Vaughan D. Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. J Neurosci 2006; 26: 7723-9.
    • (2006) J Neurosci , vol.26 , pp. 7723-7729
    • Lemon, N.1    Manahan-Vaughan, D.2
  • 34
    • 19544370227 scopus 로고    scopus 로고
    • The hippocampal-VTA loop: Controlling the entry of information into long-term memory
    • Lisman JE, Grace AA. The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron 2005; 46: 703-13.
    • (2005) Neuron , vol.46 , pp. 703-713
    • Lisman, J.E.1    Grace, A.A.2
  • 35
    • 0035179770 scopus 로고    scopus 로고
    • Storage, recall, and novelty detection of sequences by the hippocampus: Elaborating on the SOCRATIC model to account for normal and aberrant effects of dopamine
    • Lisman JE, Otmakhova NA. Storage, recall, and novelty detection of sequences by the hippocampus: elaborating on the SOCRATIC model to account for normal and aberrant effects of dopamine. Hippocampus 2001; 11: 551-68.
    • (2001) Hippocampus , vol.11 , pp. 551-568
    • Lisman, J.E.1    Otmakhova, N.A.2
  • 36
    • 2342637165 scopus 로고    scopus 로고
    • Role of NMDA receptor subtypes in governing the direction of hippo-campal synaptic plasticity
    • Liu L, Wong TP, Pozza MF, Lingenhoehl K, Wang Y, Sheng M, et al. Role of NMDA receptor subtypes in governing the direction of hippo-campal synaptic plasticity. Science 2004; 304: 1021-4.
    • (2004) Science , vol.304 , pp. 1021-1024
    • Liu, L.1    Wong, T.P.2    Pozza, M.F.3    Lingenhoehl, K.4    Wang, Y.5    Sheng, M.6
  • 37
    • 0041914628 scopus 로고    scopus 로고
    • Differential responsiveness of rat striatal nerve endings to the mito-chondrial toxin 3-nitropropionic acid: Implications for Huntington's disease
    • Marti M, Mela F, Ulazzi L, Hanau S, Stocchi S, Paganini F, et al. Differential responsiveness of rat striatal nerve endings to the mito-chondrial toxin 3-nitropropionic acid: implications for Huntington's disease. Eur J Neurosci 2003; 18: 759-67.
    • (2003) Eur J Neurosci , vol.18 , pp. 759-767
    • Marti, M.1    Mela, F.2    Ulazzi, L.3    Hanau, S.4    Stocchi, S.5    Paganini, F.6
  • 38
    • 33845872541 scopus 로고    scopus 로고
    • Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression
    • Morishita W, Lu W, Smith GB, Nicoll RA, Bear MF, Malenka RC. Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Neuropharmacol-ogy 2007; 52: 71-6.
    • (2007) Neuropharmacol-ogy , vol.52 , pp. 71-76
    • Morishita, W.1    Lu, W.2    Smith, G.B.3    Nicoll, R.A.4    Bear, M.F.5    Malenka, R.C.6
  • 39
    • 67649671746 scopus 로고    scopus 로고
    • What is remembered? Role of attention on the encoding and retrieval of hippocampal representations
    • Muzzio IA, Kentros C, Kandel E. What is remembered? Role of attention on the encoding and retrieval of hippocampal representations. J Physiol 2009; 587: 2837-54.
    • (2009) J Physiol , vol.587 , pp. 2837-2854
    • Muzzio, I.A.1    Kentros, C.2    Kandel, E.3
  • 41
    • 77956794197 scopus 로고    scopus 로고
    • Associative learning and CA3-CA1 synaptic plasticity are impaired in D1R null, Drd1a-/-mice and in hippocampal siRNA silenced Drd1a mice
    • Ortiz O, Delgado-Garcia JM, Espadas I, Bahi A, Trullas R, Dreyer JL, et al. Associative learning and CA3-CA1 synaptic plasticity are impaired in D1R null, Drd1a-/-mice and in hippocampal siRNA silenced Drd1a mice. J Neurosci 2010; 30: 12288-300.
    • (2010) J Neurosci , vol.30 , pp. 12288-12300
    • Ortiz, O.1    Delgado-Garcia, J.M.2    Espadas, I.3    Bahi, A.4    Trullas, R.5    Dreyer, J.L.6
  • 42
    • 0029997176 scopus 로고    scopus 로고
    • D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippo-campal synapses
    • Otmakhova NA, Lisman JE. D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippo-campal synapses. J Neurosci 1996; 16: 7478-86.
    • (1996) J Neurosci , vol.16 , pp. 7478-7486
    • Otmakhova, N.A.1    Lisman, J.E.2
  • 43
    • 36248987227 scopus 로고    scopus 로고
    • The medial prefrontal cortex determines the accumbens dopamine response to stress through the opposing influences of norepinephrine and dopamine
    • Pascucci T, Ventura R, Latagliata EC, Cabib S, Puglisi-Allegra S. The medial prefrontal cortex determines the accumbens dopamine response to stress through the opposing influences of norepinephrine and dopamine. Cereb Cortex 2007; 17: 2796-804.
    • (2007) Cereb Cortex , vol.17 , pp. 2796-2804
    • Pascucci, T.1    Ventura, R.2    Latagliata, E.C.3    Cabib, S.4    Puglisi-Allegra, S.5
  • 45
    • 38149033506 scopus 로고    scopus 로고
    • L-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation
    • Picconi B, Paille V, Ghiglieri V, Bagetta V, Barone I, Lindgren HS, et al. L-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation. Neurobiol Dis 2008; 29: 327-35.
    • (2008) Neurobiol Dis , vol.29 , pp. 327-335
    • Picconi, B.1    Paille, V.2    Ghiglieri, V.3    Bagetta, V.4    Barone, I.5    Lindgren, H.S.6
  • 46
    • 60149098420 scopus 로고    scopus 로고
    • Levodopa enhances synaptic plasticity in the substantia nigra pars reticulata of Parkinson's disease patients
    • Prescott IA, Dostrovsky JO, Moro E, Hodaie M, Lozano AM, Hutchison WD. Levodopa enhances synaptic plasticity in the substantia nigra pars reticulata of Parkinson's disease patients. Brain 2009; 132: 309-18.
    • (2009) Brain , vol.132 , pp. 309-318
    • Prescott, I.A.1    Dostrovsky, J.O.2    Moro, E.3    Hodaie, M.4    Lozano, A.M.5    Hutchison, W.D.6
  • 48
    • 67651021134 scopus 로고    scopus 로고
    • The neuropsychopharmacology of fronto-executive function: Monoaminergic modulation
    • Robbins TW, Arnsten AF. The neuropsychopharmacology of fronto-executive function: monoaminergic modulation. Annu Rev Neurosci 2009; 32: 267-87.
    • (2009) Annu Rev Neurosci , vol.32 , pp. 267-287
    • Robbins, T.W.1    Arnsten, A.F.2
  • 50
    • 75149155105 scopus 로고    scopus 로고
    • The role of medial temporal lobe in retrieving spatial and nonspatial relations from episodic and semantic memory
    • Ryan L, Lin CY, Ketcham K, Nadel L. The role of medial temporal lobe in retrieving spatial and nonspatial relations from episodic and semantic memory. Hippocampus 2010; 20: 11-8.
    • (2010) Hippocampus , vol.20 , pp. 11-18
    • Ryan, L.1    Lin, C.Y.2    Ketcham, K.3    Nadel, L.4
  • 51
    • 2942528888 scopus 로고    scopus 로고
    • Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD
    • Sajikumar S, Frey JU. Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD. Neurobiol Learn Mem 2004; 82: 12-25.
    • (2004) Neurobiol Learn Mem , vol.82 , pp. 12-25
    • Sajikumar, S.1    Frey, J.U.2
  • 52
    • 76849114494 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity, memory, and epilepsy: Effects of long-term valproic acid treatment
    • Sgobio C, Ghiglieri V, Costa C, Bagetta V, Siliquini S, Barone I, et al. Hippocampal synaptic plasticity, memory, and epilepsy: effects of long-term valproic acid treatment. Biol Psychiatry 2010; 67: 567-74.
    • (2010) Biol Psychiatry , vol.67 , pp. 567-574
    • Sgobio, C.1    Ghiglieri, V.2    Costa, C.3    Bagetta, V.4    Siliquini, S.5    Barone, I.6
  • 53
    • 67650410009 scopus 로고    scopus 로고
    • Distinct hippo-campal and basal ganglia contributions to probabilistic learning and reversal
    • Shohamy D, Myers CE, Hopkins RO, Sage J, Gluck MA. Distinct hippo-campal and basal ganglia contributions to probabilistic learning and reversal. J Cogn Neurosci 2009; 21: 1821-33.
    • (2009) J Cogn Neurosci , vol.21 , pp. 1821-1833
    • Shohamy, D.1    Myers, C.E.2    Hopkins, R.O.3    Sage, J.4    Gluck, M.A.5
  • 54
    • 0345269239 scopus 로고    scopus 로고
    • Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice
    • Steidl JV, Gomez-Isla T, Mariash A, Ashe KH, Boland LM. Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice. Neuroreport 2003; 14: 219-23.
    • (2003) Neuroreport , vol.14 , pp. 219-223
    • Steidl, J.V.1    Gomez-Isla, T.2    Mariash, A.3    Ashe, K.H.4    Boland, L.M.5
  • 57
    • 33646097224 scopus 로고    scopus 로고
    • Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120) : Implications for Lewy body disorders
    • Tofaris GK, Garcia Reitbock P, Humby T, Lambourne SL, O'Connell M, Ghetti B, et al. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. J Neurosci 2006; 26: 3942-50.
    • (2006) J Neurosci , vol.26 , pp. 3942-3950
    • Tofaris, G.K.1    Garcia Reitbock, P.2    Humby, T.3    Lambourne, S.L.4    O'Connell, M.5    Ghetti, B.6
  • 58
    • 0021864241 scopus 로고
    • Parkinson's disease: Loss of neurons from the ventral tegmental area contralateral to therapeutic surgical lesions
    • Uhl GR, Hedreen JC, Price DL. Parkinson's disease: loss of neurons from the ventral tegmental area contralateral to therapeutic surgical lesions. Neurology 1985; 35: 1215-8.
    • (1985) Neurology , vol.35 , pp. 1215-1218
    • Uhl, G.R.1    Hedreen, J.C.2    Price, D.L.3
  • 59
    • 0031968889 scopus 로고    scopus 로고
    • The pharmacology of mesocortical dopamine neurons: A dual-probe microdialysis study in the ventral tegmental area and prefrontal cortex of the rat brain
    • Westerink BH, Enrico P, Feimann J, De Vries JB. The pharmacology of mesocortical dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and prefrontal cortex of the rat brain. J Pharmacol Exp Ther 1998; 285: 143-54.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 143-154
    • Westerink, B.H.1    Enrico, P.2    Feimann, J.3    De Vries, J.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.