Screening study on hemolysis suppression effect of an alternative plasticizer for the development of a novel blood container made of polyvinyl chloride

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 102, Issue 4, 2014, Pages 721-728

  Haishima, Yuji ^a   Kawakami, Tsuyoshi ^a   Hasegawa, Chie ^a   Tanoue, Akito ^b   Yuba, Toshiyasu ^c   Isama, Kazuo ^a   Matsuoka, Atsuko ^a   Niimi, Shingo ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c Kawasumi Laboratories Inc   (Japan)

Author keywords

alternative plasticizer; blood container; DEHP; hemolysis; PVC medical device

Indexed keywords

BIOMEDICAL EQUIPMENT; CARBOXYLATION; CONTAINERS; ESTERS; PLASTICIZERS; POLYVINYL CHLORIDES; REINFORCED PLASTICS; SOLVENTS;

6-MEMBERED RINGS; DEHP; DI-2-ETHYLHEXYL PHTHALATE; DIISODECYL PHTHALATE; HEMOLYSIS; MEDICAL DEVICES; POLYVINYL CHLORIDE SHEETS (PVC); SUPPRESSION EFFECTS;

BLOOD;

ADENINE; ADIPIC ACID; CARBON; MANNITOL; PHOSPHATE; PHTHALIC ACID; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PLASTICIZER; POLYVINYLCHLORIDE; 2,3-DIHYDRO-5H-OXAZOLO(3,2-A)THIENO(3,2-D)PYRIMIDIN-5-ONE; BENZOIC ACID DERIVATIVE; CITRATE PHOSPHATE DEXTROSE; CITRIC ACID; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; DEOXYINOSINE DIPHOSPHATE; DICARBOXYLIC ACID; DIISONONYL 1,2-CYCLOHEXANEDICARBOXYLIC ACID; GLUCOSE; HEPARIN; OXAZOLE DERIVATIVE; PURINE NUCLEOTIDE; PYRIMIDINONE DERIVATIVE; TRIOCTYL TRIMELLITATE;

ANALYTICAL PARAMETERS; ARTICLE; ATOM; BLOOD STORAGE; CONTROLLED STUDY; ELUTION; GAS CHROMATOGRAPHY; HEMOLYSIS; HUMAN; LEACHABILITY; SCREENING TEST; TANDEM MASS SPECTROMETRY; CHEMICAL PHENOMENA; CHEMISTRY; COMPARATIVE STUDY; DEVICES; DRUG EFFECTS; MASS FRAGMENTOGRAPHY; STRUCTURE ACTIVITY RELATION; TOXICITY;

ADENINE; BENZOATES; BLOOD PRESERVATION; CITRATES; CYCLOHEXANECARBOXYLIC ACIDS; DEPRESSION, CHEMICAL; DICARBOXYLIC ACIDS; DIETHYLHEXYL PHTHALATE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCOSE; HEMOLYSIS; HEPARIN; HUMANS; INOSINE NUCLEOTIDES; MANNITOL; OXAZOLES; PLASTICIZERS; POLYVINYL CHLORIDE; PYRIMIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84898918253     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.33052     Document Type: Article

References (26)

1. Allwood MC,. The release of phthalate ester plasticizer from intravenous administration sets into fat emulsion. Int J Pharm 1986; 29: 233-236. (Pubitemid 16102014)
2. Loff S, Kabs F, Witt K, Sartoris J, Mandl B, Niessen KH, Waag KL,. Polyvinylchloride infusion lines expose infants to large amounts of toxic plasticizers. J Pediatr Surg 2000; 35: 1775-1781.
3. Poon R, Lecavalier P, Mueller R, Valli VE, Procter BG, Chu I,. Subchronic oral toxicity of di-n-octyl phthalate and di(2-ethylhexyl)phthalate in the rat. Food Chem Toxicol 1997; 35: 225-239. (Pubitemid 27187457)
4. Lamb JC, Chapin RE, Teague J, Lawton AD, Reel JR,. Reproductive effects of four phthalic acid esters in the mouse. Toxicol Appl Pharmacol 1987; 88: 255-269. (Pubitemid 17067909)
5. Tyl RW, Price CJ, Marr MC, Kimmel CA,. Developmental toxicity evaluation of dietary di(2-ethylhexyl)phthalate in Fischer 344 rats and CD-1 mice. Fundam Appl Toxicol 1988; 10: 395-412. (Pubitemid 18097029)
6. Richburg JH, Boekelheide K,. Mono-(2-ethylhexyl)phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes. Toxicol Appl Pharmacol 1996; 137: 42-50. (Pubitemid 26095857)
7. Lee J, Richburg JH, Shipp EB, Meistrich ML, Boekelheide K,. The Fas system, a regulator of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis. Endocrinol 1999; 140: 852-858. (Pubitemid 29058222)
8. Richburg JH, Nanex A, Williams LR, Embree ME, Boekelheide K,. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinol 2000; 141: 787-793. (Pubitemid 32250504)
9. Lovekamp TN, Davis BJ,. Mono-(2-ethylhexyl)phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells. Toxicol Appl Pharmacol 2001; 172: 217-224. (Pubitemid 32406029)
10. Habert R, Muczynski V, Lehraiki A, Lambrot R, Lécureuil C, Levacher C, Coffigny H, Pairault C, Moison D, Frydman R, Rouiller-Fabre V,. Adverse effects of endocrine disruptors on the foetal testis development: focus on the phthalates. Folia Histochem Cytobiol 2009; 47: S67-S74.
11. Lambrot R, Muczynski V, Lécureuil C, Angenard G, Coffigny H, Pairault C, Moison D, Frydman R, Habert R, Rouiller-Fabre V,. Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production. Environ Health Perspect 2009; 117: 32-37.
12. Reinsberg J, Wegener-Toper P, van der Ven K, van der Ven H, Klingmueller D,. Effect of mono-(2-ethylhexyl) phthalate on steroid production of human granulosa cells. Toxicol Appl Pharmacol 2009; 239: 116-123.
13. Silva MJ, Furr J, Preau JL Jr, Samadar E, Fray LE, Calafat AM,. Identification of potential biomarkers of exposure to di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH), an alternative for phthalate plasticizers. J Expo Sci Environ Epidemiol 2012; 22: 201-211.
14. Nair CS, Vidya R, Ashalatha PM,. Hexamoll DINCH plasticised PVC containers for the storage of platelets. Asian J Transfus Sci 2011; 5: 18-22.
15. AuBuchon JP, Estep TN, Davey RJ,. The effect of the plasticizer di-2-ethylhexyl phthalate on the survival of stored RBCs. Blood 1988; 71: 448-452. (Pubitemid 18089535)
16. Haishima Y, Isama K, Hasegawa C, Yuba T, Matsuoka A,. A development and biological safety evaluation of novel PVC medical devices with surface structures modified by UV irradiation to suppress plasticizer migration. J Biomed Mater Res A 2013; 101A: 2630-2643.
17. Dumont LJ, Baker S, Dumont DF, Herschel L, Waters S, Calcagni K, Sandford C, Radwanski K, Min K, David RM, Otter R,. Exploratory in vitro study of red blood cell storage containers formulated with an alternative plasticizer. Transfusion 2012; 52: 1439-1445.
18. Ito R, Seshimo F, Haishima Y, Hasegawa C, Isama K, Yagami T, Nakahashi K, Yamazaki H, Inoue K, Yoshimura Y, Saito K, Tsuchiya T, Nakazawa H,. Novel approach for reducing migration of di-2-ethylhexyl phthalate from polyvinyl chloride medical device. Int J Pharm 2005; 303: 104-112. (Pubitemid 41318027)
19. Haishima Y, Seshimo F, Higuchi T, Yamazaki H, Hasegawa C, Izumi S, Makino T, Nakahashi K, Ito R, Inoue K, Yoshimura Y, Saito K, Yagami T, Tsuchiya T, Nakazawa H,. Development of a simple method for predicting the levels of di(2-ethylhexyl) phthalate migrated from PVC medical devices into pharmaceutical solutions. Int J Pharm 2005; 298: 126-142. (Pubitemid 40828334)
20. Haishima Y, Matsuda R, Hayashi Y, Hasegawa C, Yagami T, Tsuchiya T,. Risk assessment of di(2-ethylhexyl) phthalate eluted from PVC blood circuits during hemodialysis and pump-oxygenation therapy. Int J Pharm 2004; 274: 119-129. (Pubitemid 38457011)
21. Kawakami T, Isama K, Matsuoka A,. Analysis of phthalic acid diesters, monoester, and other plasticizers in polyvinyl chloride household products in Japan. J Environ Sci Health A 2011; 46: 855-864.
22. Hayashi Y, Matsuda R, Haishima Y, Yagami T, Nakamura, A,. Validation of HPLC and GC-MS systems for bisphenol-A leached from hemodialyzers on the basis of FUMI theory. J Pharm Biomed Anal 2002; 28: 421-429. (Pubitemid 34465613)
23. Kambia K, Dine T, Azar R, Gressier B, Luyckx M, Brunet C,. Comparative study of the leachability of di(2-ethylhexyl) phthalate and tri(2-ethylhexyl) trimellitate from haemodialysis tubing. Int J Pharm 2001; 229: 139-146. (Pubitemid 32972088)
24. Holmgren T, Persson L, Andersson PL, Haglund P,. A generic emission model to predict release of organic substances from materials in consumer goods. Sci Total Environ 2012; 437: 306-314.
25. Burger P, Korsten H, Verhoeven AJ, Korte D, Bruggen R,. Collection and storage of red blood cells with anticoagulant and additive solution with a physiologic pH. Transfusion 2012; 52: 1245-1252.
26. Hirata-Koizumi M, Takahashi M, Matsumoto M, Kawamura T, Ono A, Hirose A,. Toxicity effects of phthalate substitute plasticizers used in toys. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku 2012; 130: 31-42.