A development and biological safety evaluation of novel PVC medical devices with surface structures modified by UV irradiation to suppress plasticizer migration

Journal of Biomedical Materials Research - Part A

Volumn 101 A, Issue 9, 2013, Pages 2630-2643

  Haishima, Yuji ^a   Isama, Kazuo ^a   Hasegawa, Chie ^a   Yuba, Toshiyasu ^b   Matsuoka, Atsuko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b Kawasumi Laboratories Inc   (Japan)

Author keywords

DEHP; MEHP; PVC medical device; surface modification; UV irradiation

Indexed keywords

CHROMOSOME ABERRATION TESTS; DEHP; DI-2-ETHYLHEXYL PHTHALATE; MEDICAL DEVICES; MEHP; MONO-(2-ETHYLHEXYL)PHTHALATE; PHYSICOCHEMICAL PROPERTY; UV IRRADIATION;

BIOMEDICAL EQUIPMENT; CYTOTOXICITY; ESTERS; METHANOL; PLASTICIZERS; REINFORCED PLASTICS; SOLVENTS; STERILIZATION (CLEANING); SURFACE TREATMENT; TOXICITY; WASHING;

POLYVINYL CHLORIDES;

DI (2 ETHYLHEXYL) PHTHALATE; METHANOL; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PLASTICIZER; POLYVINYLCHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; BIOSAFETY; CHROMOSOME ABERRATION; CYTOTOXICITY; DEVICE SAFETY; GAMMA IRRADIATION; INSTRUMENT STERILIZATION; MEDICAL DEVICE; PHYSICAL CHEMISTRY; RISK ASSESSMENT; SURFACE PROPERTY; TOXICITY; ULTRAVIOLET IRRADIATION;

DEHP; MEHP; PVC MEDICAL DEVICE; SURFACE MODIFICATION; UV IRRADIATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; CRICETINAE; CRICETULUS; DIETHYLHEXYL PHTHALATE; EQUIPMENT AND SUPPLIES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MATERIALS TESTING; PLASTICIZERS; POLYVINYL CHLORIDE; SURFACE PROPERTIES; ULTRAVIOLET RAYS;

EID: 84880596646     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34558     Document Type: Article

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