Microbial metabolism of quorum-sensing molecules acyl-homoserine lactones, γ-heptalactone and other lactones

Applied Microbiology and Biotechnology

Volumn 98, Issue 8, 2014, Pages 3401-3412

  Safari, Maryam ^a   Amache, Rana ^a   Esmaeilishirazifard, Elham ^a   Keshavarz, Tajalli ^a  

^a UNIVERSITY OF WESTMINSTER   (United Kingdom)

Author keywords

Acyl homoserine lactone (AHL); Bacteria; Butyrolactone I; Fungi; Metabolism; Quorum sensing (QS); Heptalactone

Indexed keywords

ESTERS; FUNGI; METABOLISM; MICROBIOLOGY; MOLECULES; PHYSIOLOGY;

ACYL-HOMOSERINE LACTONES; BUTYROLACTONE-I; CELL-TO-CELL COMMUNICATION; GRAM-NEGATIVE BACTERIA; MICROBIAL COMMUNITIES; QUORUM-SENSING; QUORUM-SENSING MOLECULES; SIGNALLING MOLECULES;

BACTERIA;

GAMMA HEPTALACTONE; LACTONE; LACTONE DERIVATIVE; N ACYLHOMOSERINE LACTONE; UNCLASSIFIED DRUG;

BACTERIUM; BIOLOGICAL FUNCTIONS; DRUG STRUCTURE; ENERGY RESOURCE; FUNGUS; MICROBIAL METABOLISM; NONHUMAN; QUORUM SENSING; REVIEW; BACTERIAL PHENOMENA AND FUNCTIONS; METABOLISM; PHYSIOLOGY;

BACTERIAL PHYSIOLOGICAL PHENOMENA; FUNGI; LACTONES; QUORUM SENSING;

EID: 84898897597     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-5518-9     Document Type: Review

References (125)

1. Anderson A, Hacking A, Dawes E (1987) Alternative pathways for the biosynthesis of alginate from fructose and glucose in Pseudomonas mendocina and Azotobacter vinelandii. J Gen Microbiol 133:1045-1052
2. Antunes LCM, Ferreira RBR, Buckner MMC, Finlay BB (2010) Quorum sensing in bacterial virulence. Microbiology 156:2271-2282
3. Arthur LO, Bulla LA, Julian GS, Nakamura LK (1973) Carbohydrate metabolism in Agrobacterium tumefaciens. J Bacteriol 116:304-313
4. Basha KM, Rajendran A, Thangavelu V (2010) Recent advances in the biodegradation of phenol: a review. Asian J Exp Biol Sci 1:219-234
5. Bassler, B. L. & Miller, M. B. (2013) Quorum sensing. The prokaryotes. Springer, Berlin, pp. 495-509
6. Beeson WT, Iavarone AT, Hausmann CD, Cate JH, Marletta MA (2011) Extracellular aldonolactonase from Myceliophthora thermophila. Appl Environ Microbiol 77:650-656
7. Beppu T (1992) Secondary metabolites as chemical signals for cellular differentiation. Gene 115:159-165
8. Beppu T (1995) Signal transduction and secondary metabolism: prospects for controlling productivity. Trends Biotechnol 13:264-269
9. Borodina I, Krabben P, Nielsen J (2005) Genome-scale analysis of Streptomyces coelicolor A3 (2) metabolism. Genome Res 15:820-829
10. Brooks SL, Van Hamme JD (2012) Whole-genome shotgun sequence of Rhodococcus species strain JVH1. J Bacteriol 194:5492-5493
11. Byers JT, Lucas C, Salmond GPC, Welch M (2002) Nonenzymatic turnover of an Erwinia carotovora quorum-sensing signaling molecule. J Bacteriol 184:1163-1171
12. Calvo AM, Wilson RA, Bok JW, Keller NP (2002) Relationship between secondary metabolism and fungal development. Microbiol Mol Biol Rev 66:447-459
13. Carlier A, Uroz S, Smadja B, Fray R, Latour X, Dessaux Y, Faure D (2003) The Ti plasmid of Agrobacterium tumefaciens harbors an attM-paralogous gene, aiiB, also encoding N-acyl homoserine lactonase activity. Appl Environ Microbiol 69:4989-4993
14. Carlier A, Chevrot R, Dessaux Y, Faure D (2004) The assimilation of γ-butyrolactone in Agrobacterium tumefaciens C58 interferes with the accumulation of the N-acyl-homoserine lactone signal. Mol Plant-Microbe Interact 17:951-957
15. Cazar ME, Schmeda-Hirschmann G, Astudillo L (2005) Antimicrobial butyrolactone I derivatives from the Ecuadorian soil fungus Aspergillus terreus Thorn. var terreus. World J Microbiol Biotechnol 21:1067-1075
16. Cheetham PS (1993) The use of biotransformations for the production of flavours and fragrances. Trends Biotechnol 11:478-488
17. Chen H, Fujita M, Feng Q, Clardy J, Fink GR (2004) Tyrosol is a quorum-sensing molecule in Candida albicans. Proc Natl Acad Sci U S A 101:5048-5052
18. Chernin LS, Winson MK, Thompson JM, Haran S, Bycroft BW, Chet I, Williams P, Stewart GS (1998) Chitinolytic activity in Chromobacterium violaceum: substrate analysis and regulation by quorum sensing. J Bacteriol 180:4435-4441
19. Chowdhary PK, Keshavan N, Nguyen HQ, Peterson JA, González JE, Haines DC (2007) Bacillus megaterium CYP102A1 oxidation of acyl homoserine lactones and acyl homoserines. Biochemistry 46:14429-14437
20. Chun CK, Ozer EA, Welsh MJ, Zabner J, Greenberg EP (2004) Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia. Proc Natl Acad Sci U S A 101:3587-3590
21. Cole M (1966) Formation of 6-aminopenicillanic acid, penicillins, and penicillin acylase by various fungi. Appl Microbiol 14:98-104
22. Conway T (1992) The Entner-Doudoroff pathway: history, physiology and molecular biology. FEMS Microbiol Lett 103:1-27
23. Czajkowski R, Jafra S (2009) Quenching of acyl-homoserine lactone-dependent quorum sensing by enzymatic disruption of signal molecules. Acta Biochim Pol 56:1-16
24. D'Angelo-Picard C, Faure D, Penot I, Dessaux Y (2005) Diversity of N-acyl homoserine lactone-producing and -degrading bacteria in soil and tobacco rhizosphere. Environ Microbiol 7:1796-1808
25. Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton J, Greenberg E (1998) The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 280:295-298
26. De Kievit TR, Iglewski BH (2000) Bacterial quorum sensing in pathogenic relationships. Infect Immun 68:4839-4849
27. Decho AW, Visscher PT, Ferry J, Kawaguchi T, He L, Przekop KM, Norman RS, Reid RP (2009) Autoinducers extracted from microbial mats reveal a surprising diversity of Nacylhomoserine lactones (AHLs) and abundance changes that may relate to diel pH. Environ Microbiol 11:409-420
28. Delalande L, Faure D, Raffoux A, Uroz S, D'Angelo-Picard C, Elasri M, Carlier A, Berruyer R, Petit A, Williams P, Dessaux Y (2005) N-Hexanoyl-l-homoserine lactone, a mediator of bacterial quorum-sensing regulation, exhibits plant-dependent stability and may be inactivated by germinating Lotus corniculatus seedlings. FEMS Microbiol Ecol 52:13-20
29. Demain AL (2010) Induction of microbial secondary metabolism. Int Microbiol 1:259-264
30. Dessaux Y, Chapelle E, Faure D (2011) Quorum sensing and quorum quenching in soil ecosystems. In: Witzany G (ed) Biocommunication in soil microorganisms. Springer, Berlin, pp 339-367
31. Dong Y-H, Xu J-L, Li X-Z, Zhang L-H (2000) AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora. P Natl Acad Sci 97:3526-3531
32. Dong Y-H, Wang L-H, Xu J-L, Zhang H-B, Zhang X-F, Zhang L-H (2001) Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase. Nature 411:813-817
33. Dong Y-H, Gusti AR, Zhang Q, Xu J-L, Zhang L-H (2002) Identification of quorum-quenching N-acyl homoserine lactonases from Bacillus species. Appl Environ Microbiol 68:1754-1759
34. Dong Y-H, Wang L-H, Zhang L-H (2007) Quorum-quenching microbial infections: mechanisms and implications. Phil Trans R Soc B 362:1201-1211
35. Engebrecht J, Nealson K, Silverman M (1983) Bacterial bioluminescence: isolation and genetic analysis of functions from Vibrio fischeri. Cell 32:773-781
36. English N, Palmer CN, Alworth WL, Kang L, Hughes V, Wolf CR (1997) Fatty acid signals in Bacillus megaterium are attenuated by cytochrome P-450-mediated hydroxylation. Biochem J 327:363-368
37. Flagan S, Ching W-K, Leadbetter JR (2003) Arthrobacter strain VAI-A utilizes acyl-homoserine lactone inactivation products and stimulates quorum signal biodegradation by Variovorax paradoxus. Appl Environ Microbiol 69:909-916
38. Flärdh K, Buttner MJ (2009) Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium. Nat Rev Microbiol 7:36-49
39. Fuchs G, Boll M, Heider J (2011) Microbial degradation of aromatic compounds - from one strategy to four. Nat Rev Microbiol 9:803-816
40. Fuqua C, Eberhard A (1999) Signal generation in autoinduction systems: synthesis of acylated homoserine lactones by LuxI-type proteins. Cell-cell signaling in bacteria. ASM, Washington, DC, pp 211-230
41. Fuqua C, Greenberg EP (2002) Listening in on bacteria: acyl-homoserine lactone signalling. Nat Rev Mol Cell Biol 3:685-695
42. Fuqua WC, Winans SC, Greenberg EP (1994) Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J Bacteriol 176:269
43. Fuqua C, Parsek MR, Greenberg EP (2001) Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annu Rev Genet 35:439-468
44. Grant DR, Voelkert E (1970) The effect of temperature and light on the accumulation of homoserine in pea seedlings. Phytochemistry 9:985-990
45. Gunsalus I, Horecker B, Wood W (1955) Pathways of carbohydrate metabolism in microorganisms. Bacteriol Rev 19:79
46. Hardman AM, Stewart GS, Williams P (1998) Quorum sensing and the cell-cell communication dependent regulation of gene expression in pathogenic and non-pathogenic bacteria. Anton Leeuw J Microb 74:199-210
47. Harwood CS, Parales RE (1996) The β-ketoadipate pathway and the biology of self-identity. Annu Rev Microbiol 50:553-590
48. Ho P, Fulco A (1976) Involvement of a single hydroxylase species in the hydroxylation of palmitate at the omega-1, omega-2 and omega-3 positions by a preparation from Bacillus megaterium. Biochim Biophys Acta 431:249-256
49. Hogan DA (2006) Talking to themselves: autoregulation and quorum sensing in fungi. Eukaryot Cell 5:613-619
50. Honda K, Tsuboi H, Minetoki T, Nose H, Sakamoto K, Kataoka M, Shimizu S (2005) Expression of the Fusarium oxysporum lactonase gene in Aspergillus oryzae: molecular properties of the recombinant enzyme and its application. Appl Microbiol Biotechnol 66:520-526
51. Hornby JM, Jensen EC, Lisec AD, Tasto JJ, Jahnke B, Shoemaker R, Dussault P, Nickerson KW (2001) Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. Appl Environ Microbiol 67:2982-2992
52. Huang JJ, Han J-I, Zhang L-H, Leadbetter JR (2003) Utilization of acyl-homoserine lactone quorum signals for growth by a soil pseudomonas and Pseudomonas aeruginosa PAO1. Appl Environ Microbiol 69:5941-5949
53. Kang BR, Lee JH, Ko SJ, Lee YH, Cha JS, Cho BH, Kim YC (2004) Degradation of acyl-homoserine lactone molecules by Acinetobacter sp. strain C1010. Can J Microbiol 50:935-941
54. Kataoka M, Honda K, Sakamoto K, Shimizu S (2007) Microbial enzymes involved in lactone compound metabolism and their biotechnological applications. Appl Microbiol Biot 75:257-266
55. Kaufmann GF, Sartorio R, Lee S-H, Rogers CJ, Meijler MM, Moss JA, Clapham B, Brogan AP, Dickerson TJ, Janda KD (2005) Revisiting quorum sensing: discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones. Proc Natl Acad Sci U S A 102:309-314
56. Krings U, Berger R (1998) Biotechnological production of flavours and fragrances. Appl Microbiol Biotechnol 49:1-8
57. Latifi A, Foglino M, Tanaka K, Williams P, Lazdunski A (1996) A hierarchical quorum sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary phase sigma factor RpoS. Mol Microbiol 21:1137-1146
58. Leadbetter JR, Greenberg E (2000) Metabolism of acyl-homoserine lactone quorum-sensing signals by Variovorax paradoxus. J Bacteriol 182:6921-6926
59. Lee SJ, Park S-Y, Lee J-J, Yum D-Y, Koo B-T, Lee J-K (2002) Genes encoding the N-acyl homoserine lactone-degrading enzyme are widespread in many subspecies of Bacillus thuringiensis. Appl Environ Microbiol 68:3919-3924
60. Lin YH, Xu JL, Hu J, Wang LH, Ong SL, Leadbetter JR, Zhang LH (2003) Acyl-homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum-quenching enzymes. Mol Microbiol 47:849-860
61. Liu CF, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D (2013) A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis. Biochemistry 52:1603-1610
62. MacMillan J, Seaton J, Suter P (1961) Isolation and structures of gibberellins from higher plants. Adv Chem Ser 28:18-25
63. Martínez-Hernández JL, Mata-Gómez MA, Aguilar-González CN, Ilyina A (2010) A process to produce penicillin G acylase by surface-adhesion fermentation using Mucor griseocyanus to obtain 6-aminopenicillanic acid by penicillin G hydrolysis. Appl Biochem Biotechnol 160:2045-2053
64. McClean KH, Winson MK, Fish L, Taylor A, Chhabra SR, Camara M, Daykin M, Lamb JH, Swift S, Bycroft BW (1997) Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology 143:3703-3711
65. Merfort I (2011) Perspectives on sesquiterpene lactones in inflammation and cancer. Curr Drug Targets 12:1560-1573
66. Metzler DE, Metzler CM (2003) Biochemistry: the chemical reactions of living cells. Academic, San Diego
67. Miller MB, Bassler BL (2001) Quorum sensing in bacteria. Annu Rev Microbiol 55:165-199
68. Natrah F, Defoirdt T, Sorgeloos P, Bossier P (2011) Disruption of bacterial cell-to-cell communication by marine organisms and its relevance to aquaculture. Mar Biotechnol 13:109-126
69. Nealson K, Hastings JW (1979) Bacterial bioluminescence: its control and ecological significance. Microbiol Rev 43:496
70. Ornston L, Stanier R (1966) The conversion of catechol and protocatechuate to β-ketoadipate by Pseudomonas putida I. Biochemistry. J Biol Chem 241:3776-3786
71. Palleroni NJ, Doudoroff M (1957) Metabolism of carbohydrates by Pseudomonas saccharophila III. Oxidation of d-arabinose. J Bacteriol 74:180-185
72. Park S-Y, Lee SJ, Oh T-K, Oh J-W, Koo B-T, Yum D-Y, Lee J-K (2003) AhlD, an N-acylhomoserine lactonase in Arthrobacter sp., and predicted homologues in other bacteria. Microbiology 149:1541-1550
73. Park S-Y, Kang H-O, Jang H-S, Lee J-K, Koo B-T, Yum D-Y (2005) Identification of extracellular N-acylhomoserine lactone acylase from a Streptomyces sp. and its application to quorum quenching. Appl Environ Microbiol 71:2632-2641
74. Park SY, Hwang BJ, Shin MH, Kim J, Kim HK, Lee JK (2006) N-Acylhomoserine lactonase producing Rhodococcus spp. with different AHL-degrading activities. FEMS Microbiol Lett 261:102-108
75. Parsek MR, Val DL, Hanzelka BL, Cronan JE, Greenberg EP (1999) Acyl homoserine-lactone quorum-sensing signal generation. P Natl Acad Sci 96:4360-4365
76. Pearson JP, Gray KM, Passador L, Tucker KD, Eberhard A, Iglewski BH, Greenberg E (1994) Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. P Natl Acad Sci 91:197-201
77. Pearson JP, Passador L, Iglewski BH, Greenberg E (1995) A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. P Natl Acad Sci 92:1490-1494
78. Peekhaus N, Conway T (1998) What's for dinner?: Entner-Doudoroff metabolism in Escherichia coli. J Bacteriol 180:3495-3502
79. Piper KR, von Bodman SB, Farrand SK (1993) Conjugation factor of Agrobacterium tumefaciens regulates Ti plasmid transfer by autoinduction. Nature 362:448-450
80. Raina S, Odell M, Keshavarz T (2010) Quorum sensing as a method for improving sclerotiorin production in Penicillium sclerotiorum. J of Biotechnol 148:91-98
81. Raina S, De Vizio D, Palonen EK, Odell M, Brandt AM, Soini JT, Keshavarz T (2012) Is quorum sensing involved in lovastatin production in the filamentous fungus Aspergillus terreus? Process Biochem 47:843-852
82. Rashid R, Morohoshi T, Someya N, Ikeda T (2011) Degradation of N-acylhomoserine lactone quorum sensing signaling molecules by potato root surface-associated Chryseobacterium strains. Microbes Environ 26:144-148
83. Rasmussen TB, Givskov M (2006) Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol 296:149-161
84. Reyes F, Martinez M, Alfonso C, Copa-Patiño J, Soliveri J (1990) Cephalosporin C acylase in the autolysis of filamentous fungi. J Pharm Pharmacol 42:128-131
85. Roche DM, Byers JT, Smith DS, Glansdorp FG, Spring DR, Welch M (2004) Communications blackout? Do N-acylhomoserine-lactone-degrading enzymes have any role in quorum sensing? Microbiology 150:2023-2028
86. Rodriguez E, Towers G, Mitchell J (1976) Biological activities of sesquiterpene lactones. Phytochemistry 15:1573-1580
87. Ronson CW, Primrose SB (1979) Carbohydrate metabolism in Rhizobium trifolii: identification and symbiotic properties of mutants. J Gen Microbiol 112:77-88
88. Schertzer JW, Boulette ML, Whiteley M (2009) More than a signal: non-signaling properties of quorum sensing molecules. Trends Microbiol 17:189-195
89. Schimmel TG, Coffman AD, Parsons SJ (1998) Effect of butyrolactone I on the producing fungus, Aspergillus terreus. Appl Environ Microb 64:3707-3712
90. Shepherd RW, Lindow SE (2009) Two dissimilar N-acyl-homoserine lactone acylases of Pseudomonas syringae influence colony and biofilm morphology. Appl Environ Microbiol 75:45-53
91. Sio CF, Otten LG, Cool RH, Diggle SP, Braun PG, Bos R, Daykin M, Cámara M, Williams P, Quax WJ (2006) Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1. Infect Immun 74:1673-1682
92. Skinner K, Cuiffetti L, Hyman M (2009) Metabolism and cometabolism of cyclic ethers by a filamentous fungus, a Graphium sp. Appl Environ Microbiol 75:5514-5522
93. Sorrentino F, Roy I, Keshavarz T (2010) Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures. Appl Microbiol Biotechnol 88:65-73
94. Sunder AV, Kumar A, Naik N, Pundle AV (2012) Characterization of a new Bacillus cereus ATUAVP1846 strain producing penicillin V acylase, and optimization of fermentation parameters. Ann Microbiol 62:1287-1293
95. Swift S, Lynch MJ, Fish L, Kirke DF, Tomás JM, Stewart GS, Williams P (1999) Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila. Infect Immun 67:5192-5199
96. Takano E, Nihira T, Hara Y, Jones JJ, Gershater CJ, Yamada Y, Bibb M (2000) Purification and structural determination of SCB1, a γ- butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3 (2). J Biol Chem 275:11010-11016
97. Tannieres M, Beury-Cirou A, Faure D (2011) Growth biostimulation of quorum-quenching bacteria by gammagamma-heptalactone treatment in the hydroponic rhizosphere of Solanum tuberosum. Commun Agric Appl Biol Sci 77:29-37
98. Tsitsigiannis DI, Keller NP (2007) Oxylipins as developmental and host-fungal communication signals. Trends Microbiol 15:109-118
99. Ueda S, Sakamoto K, Oohata N, Tsuboi M, Yamashita M, Hino M, Yamada M, Hashimoto S (2009) Screening and characterization of microorganisms with FR901379 acylase activity. J Antibiot 63:65-70
100. Ueda S, Shibata T, Ito K, Oohata N, Yamashita M, Hino M, Yamada M, Isogai Y, Hashimoto S (2010) Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907. J Antibiot 64:169-175
101. Ulrich RL (2004) Quorum quenching: enzymatic disruption of N-acylhomoserine lactone-mediated bacterial communication in Burkholderia thailandensis. Appl Environ Microbiol 70:6173-6180
102. Uroz S, Heinonsalo J (2008) Degradation of N-acyl homoserine lactone quorum sensing signal molecules by forest root-associated fungi. FEMS Microbiol Ecol 65:271-278
103. Uroz S, D'Angelo-Picard C, Carlier A, Elasri M, Sicot C, Petit A, Oger P, Faure D, Dessaux Y (2003) Novel bacteria degrading N-acylhomoserine lactones and their use as quenchers of quorum-sensing-regulated functions of plant-pathogenic bacteria. Microbiology 149:1981-1989
104. Uroz S, Chhabra SR, Cámara M, Williams P, Oger P, Dessaux Y (2005) N-Acylhomoserine lactone quorum-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities. Microbiology 151:3313-3322
105. Uroz S, Oger P, Chhabra SR, Cámara M, Williams P, Dessaux Y (2007) N-Acyl homoserine lactones are degraded via an amidolytic activity in Comamonas sp. strain D1. Arch Microbiol 187:249-256
106. Uroz S, Oger PM, Chapelle E, Adeline M-T, Faure D, Dessaux Y (2008) A Rhodococcus qsdA-encoded enzyme defines a novel class of large-spectrum quorum-quenching lactonases. Appl Environ Microbiol 74:1357-1366
107. Uroz S, Dessaux Y, Oger P (2009) Quorum sensing and quorum quenching: the yin and yang of bacterial communication. ChemBioChem 10:205-216
108. Utermark J, Karlovsky P (2007) Role of zearalenone lactonase in protection of Gliocladium roseum from fungitoxic effects of the mycotoxin zearalenone. Appl Environ Microbiol 73:637-642
109. Vandamme E, Voets P (1974) Microbiol penicillin acylases. Adv Appl Microbiol 17:311
110. Wang YJ, Huang JJ, Leadbetter JR (2007) Acyl-HSL signal decay: intrinsic to bacterial cell-cell communications. Adv Appl Microbiol 61:27-58
111. Wang W-Z, Morohoshi T, Someya N, Ikeda T (2012) AidC, a novel N-acylhomoserine lactonase from the potato root-associated Cytophaga- Flavobacteria-Bacteroides (CFB) group bacterium Chryseobacterium sp. strain StRB126. Appl Environ Microbiol 78:7985-7992
112. Waters CM, Bassler BL (2005) Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol 21:319-346
113. Weber W, Schoenmakers R, Spielmann M, El-Baba MD, Folcher M, Keller B, Weber CC, Link N, van de Wetering P, Heinzen C (2003) Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice. Nucleic Acids Res 31:e71
114. Wheeler GL, Jones MA, Smirnoff N (1998) The biosynthetic pathway of vitamin C in higher plants. Nature 393:365-369
115. Whitehead N, Byers J, Commander P, Corbett M, Coulthurst S, Everson L, Harris AP, Pemberton C, Simpson NL, Slater H, Smith D, Welch M, Williamson N, Salmond GC (2002) The regulation of virulence in phytopathogenic Erwinia species: quorum sensing, antibiotics and ecological considerations. Anton Leeuw J Microbiol 81:223-231
116. Williams P (2007) Quorum sensing, communication and cross-kingdom signalling in the bacterial world. Microbiology 153:3923-3938
117. Williams H, Steele JP, Clements M, Keshavarz T (2012) γ-Heptalactone is an endogenously produced quorum-sensing molecule regulating growth and secondary metabolite production by Aspergillus nidulans. Appl Microbiol Biotechnol 96:773-781
118. Yang YK, Morikawa M, Shimizu H, Shioya S, Suga K i, Nihira T, Yamada Y (1996) Maximum virginiamycin production by optimization of cultivation conditions in batch culture with autoregulator addition. Biotechnol Bioeng 49:437-444
119. Yates EA, Philipp B, Buckley C, Atkinson S, Chhabra SR, Sockett RE, Goldner M, Dessaux Y, Cámara M, Smith H (2002) N-Acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infect Immun 70:5635-5646
120. Yemendzhiev H, Gerginova M, Krastanov A, Stoilova I, Alexieva Z (2008) Growth of Trametes versicolor on phenol. J Ind Microbiol Biotechnol 35:1309-1312
121. Yim G, Wang HH, FRS JD (2007) Antibiotics as signalling molecules. Phil Trans R Soc B 362:1195-1200
122. Yong Y-C, Zhong J-J (2010) N-Acylated homoserine lactone production and involvement in the biodegradation of aromatics by an environmental isolate of Pseudomonas aeruginosa. Process Biochem 45:1944-1948
123. Zhang L, Murphy PJ, Kerr A, Tate ME (1993) Agrobacterium conjugation and gene regulation by N-acyl-l-homoserine lactones. Nature 362:446-448
124. Zhang H-B, Wang L-H, Zhang L-H (2002) Genetic control of quorum-sensing signal turnover in Agrobacterium tumefaciens. Proc Natl Acad Sci 99:4638-4643
125. Zhang D, Koreishi M, Imanaka H, Imamura K, Nakanishi K (2007) Cloning and characterization of penicillin V acylase from Streptomyces mobaraensis. J Biotechnol 128:788-800