Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skin

Age

Volumn 36, Issue 1, 2014, Pages 353-364

  Qin, Zhaoping ^a   Okubo, Toru ^a   Voorhees, John J ^a   Fisher, Gary J ^a   Quan, Taihao ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

CCN1; Collagen homeostasis; Fibroblasts; IL 1 ; Inflammaging

Indexed keywords

COLLAGEN FIBRIL; COLLAGEN TYPE 1; CYSTEINE RICH PROTEIN 61; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE;

ADULT; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CUTANEOUS PARAMETERS; HUMAN; HUMAN TISSUE; LONG TERM EXPOSURE; SKIN FIBROBLAST; SUN EXPOSURE; ULTRAVIOLET IRRADIATION; UPREGULATION;

ADULT; BLOTTING, WESTERN; CELLS, CULTURED; COLLAGEN TYPE I; CYSTEINE-RICH PROTEIN 61; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; MICROSCOPY, ATOMIC FORCE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; SKIN AGING; SUNLIGHT; TRANSFECTION; UP-REGULATION;

EID: 84898884539     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-013-9565-4     Document Type: Article

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