The G1662S NaV1.8 mutation in small fibre neuropathy: Impaired inactivation underlying DRG neuron hyperexcitability

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 85, Issue 5, 2014, Pages 499-505

  Han, Chongyang ^a   Vasylyev, Dmytro ^a   Macala, Lawrence J ^a   Gerrits, Monique M ^b   Hoeijmakers, Janneke G J ^b   Bekelaar, Kim J ^b   Dib Hajj, Sulayman D ^a   Faber, Catharina G ^b   Merkies, Ingemar S J ^b,c   Waxman, Stephen G ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Department of Orthopaedic Surgery   (Netherlands)

^d VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; DULOXETINE; GABAPENTIN; SODIUM CHANNEL NAV1.8;

ADULT; ANALGESIA; ANIMAL CELL; ARTICLE; BODY TEMPERATURE DISORDER; CASE REPORT; CONSTIPATION; DEPOLARIZATION; DIARRHEA; DISEASE EXACERBATION; DIZZINESS; DNA SEQUENCE; DRY EYE; EXON; FEMALE; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENETIC SCREENING; GENETIC VARIABILITY; HEART PALPITATION; HOT FLUSH; HUMAN; HUMAN TISSUE; HYPERHIDROSIS; LEG PAIN; MIDDLE AGED; MOUSE; NERVE CONDUCTION; NERVE EXCITABILITY; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOSTATIC INTOLERANCE; PAIN; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RESTLESS LEGS SYNDROME; SENSORY ANALYSIS; SKIN BIOPSY; SKIN TINGLING; SMALL FIBER NEUROPATHY; SPINAL GANGLION; VOLTAGE CLAMP TECHNIQUE; XEROSTOMIA; YOUNG ADULT;

NEUROPATHY; PAIN;

ERYTHROMELALGIA; FEMALE; GANGLIA, SPINAL; HUMANS; MIDDLE AGED; MUTATION; NAV1.7 VOLTAGE-GATED SODIUM CHANNEL; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; PATCH-CLAMP TECHNIQUES; YOUNG ADULT;

EID: 84898844324     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2013-306095     Document Type: Article

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