Enforcement of γδ-lineage commitment by the pre-T-cell receptor in precursors with weak γδd-TCR signals

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 15, 2014, Pages 5658-5663

  Zarin, Payam ^a   Wong, Gladys W ^a   Mohtashami, Mahmood ^a   Wiest, David L ^b   Züñiga Pflücker, Juan Carlos ^a  

^a Canada   (Canada)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Notch; T cell development; selection; T lineage

Indexed keywords

5' NUCLEOTIDASE; INHIBITOR OF DIFFERENTIATION 3; NUCLEAR RECEPTOR RELATED FACTOR 1; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA DELTA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REARRANGEMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STROMA CELL; THYMOCYTE;

NOTCH; T-CELL DEVELOPMENT; Β-SELECTION; ΓΔ T-LINEAGE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; LIKELIHOOD FUNCTIONS; MICE; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; THYMOCYTES;

EID: 84898829823     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312872111     Document Type: Article

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