Antimycobacterial, anti-inflammatory and genotoxicity evaluation of plants used for the treatment of tuberculosis and related symptoms in South Africa

Journal of Ethnopharmacology

Volumn 153, Issue 2, 2014, Pages 386-391

  Madikizela, B ^a   Ndhlala, A R ^a   Finnie, J F ^a   Van Staden, J ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

Ames test: anti inflammatory; Mycobacterium tuberculosis; Pentanisia prunelloides; Terminalia phanerophlebia

Indexed keywords

ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; PLANT EXTRACT;

AFRICAN MEDICINE; DNA DAMAGE; DRUG EFFECTS; DRUG SCREENING; ETHNOLOGY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; PHYSIOLOGY; PROCEDURES; SOUTH AFRICA; TREATMENT OUTCOME; TUBERCULOSIS;

ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; DNA DAMAGE; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; MEDICINE, AFRICAN TRADITIONAL; MYCOBACTERIUM TUBERCULOSIS; PLANT EXTRACTS; SOUTH AFRICA; TREATMENT OUTCOME; TUBERCULOSIS;

EID: 84898828120     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.02.034     Document Type: Article

References (37)

1. M.D. Antoun, Z. Ramos, J. Vazques, I. Oquendo, G.R. Proctor, L. Gerena, and S.G. Franzblau Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities Phytother. Res. 15 2001 638 642
2. K. Bansal, N. Kapoor, Y. Narayana, G. Puzo, M. Gilleron, and K.N. Balaji PIM2 induced COX-2 and MMP-9 expression in macrophages requires PI3K and notch1 signaling PloS One 4 2009 e4911
3. A.L. Blobaum, and L.J. Marnett Structural and functional basis of cyclooxygenase inhibition J. Med. Chem. 50 2007 1425 1441
4. L.E. Connolly, P.H. Edelstein, and L. Ramakrishnan Why is long-term therapy required to cure tuberculosis? PLoS Med. 4 2007 435 442
5. T.M. Daniel The history of tuberculosis Respiratory 100 2006 1862 1870
6. N.M. Davies, K.A. Sharkey, S. Asfaha, W.K. Macnaughton, and J.L. Wallace Aspirin causes rapid up-regulation of cyclo-oxygenase-2 expression in the stomach of rats Alimentary Pharmacol. Ther. 11 1997 1101 1108
7. I. Dey, K. Keller, A. Belley, and K. Chadee Identification and characterization of a cyclooxygenase-like enzyme from Entamoeba histolytica Prec. Natl. Acad. Sci. 100 2003 13561 13566
8. I.M.S. Eldeen, E.E. Elgorashi, and J. van Staden Antibacterial, anti-inflammatory, anti-cholinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine J. Ethnopharmacol. 102 2005 457 464
9. E.E. Elgorashi, J.L.S. Taylor, A. Maes, J. Van Staden, N. De Kimpe, and L. Verschaeve Screening of medicinal plants used in South African traditional medicine for genotoxicity effects Toxicol. Lett. 143 2003 195 207
10. J.N. Eloff, D.R. Katerere, and L.J. McGaw The biological activity and chemistry of the southern African Combretaceae J. Ethnopharmacol. 119 2008 686 699
11. C.W. Fennell, K.L. Lindsey, L.J. McGaw, S.G. Sparg, G.I. Stafford, E.E. Elgorashi, O.M. Grace, and J. Van Staden Assessing African medicinal plants for efficacy and safety pharmacological screening and toxicology J. Ethnopharmacol. 94 2004 205 217
12. B.H. Havsteen The biochemistry and medical significance of the flavonoids Pharmacol. Ther. 96 2002 67 202
13. G.P.S. Jadaun, C. Agarwal, H. Sharma, Z. Ahmed, P. Upadhyay, A.K. Faujdar, J. Gupta, R. Das, P. Gupta, D.S. Chauhan, V.D. Sharma, and V.M. Katoch Determination of ethambutol MICs for Mycobacterium tuberculosis and Mycobacterium avium isolates by resazurin microtiter assay J. Antimicrob. Chemother. 60 2007 152 311
14. A.K. Jäger, A. Hutchings, and J. Van Staden Screening of Zulu medicinal plants for prostaglandins-synthesis inhibitors J. Ethnopharmacol. 52 1996 95 100
15. G.P.P. Kamatou, S.F. van Vuuren, F.R. van Heerden, T. Seaman, and A.M. Viljoen Antibacterial and antimycobacterial activities of South African indigenous Salvia species and isolated compounds from S. chamelaeagnea S. Afr. J. Botany 73 2007 552 557
16. N.A. Knechel Tuberculosis: pathophysiology, clinical features, and diagnosis J. High Acuity Progres. Crit. Care 29 2009 34 43
17. V. Kuete, B. Ngameni, A.T. Mbaveng, B. Ngadjuib, M. Meyer, and N. Lall Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and anti-reverse transcriptase activities Acta Trop. 116 2010 100 104
18. V. Kuete, T.K. Tabopda, B. Ngameni, F. Nana, T.E. Tshikalange, and B.T. Ngadjui Antimycobacterial, antibacterial and antifungal activities of Terminalia superba (Combretaceae) S. Afr. J. Botany 76 2010 125 131
19. H.M. Lai, N.A. Mazlan, S.A.M. Yusoff, S.N. Harun, L.J. Wee, and F.R.M. Thambrin Management of side effects and drug interactions of anti-mycobacterial in tuberculosis WebmedCent. Infect. Dis. 2 2011 WMC002749
20. N. Lall, and J.M. Meyer In vitro inhibition of drug-resistant and drug-sensitive strains of Mycobacterium tuberculosis by ethnobotanically selected South African plants J. Ethnopharmacol. 66 1999 347 354
21. K. Lindsey, A.K. Jäger, D.M. Raidoo, and J. Van Staden Screening of plants used by Southern African traditional healers in the treatment of dysmenorrhoea for prostaglandin-synthesis inhibitors and uterine relaxing activity J. Ethnopharmacol. 64 1999 9 14
22. A.P.G. Macabeo, F.A. Tudla, K. Krohn, and S.G. Franzblau Antitubercular activity of the semi-polar extractives of Uvaria rufa Asian Pac. J. Trop. Med. 5 2012 777 780
23. B. Madikizela, A.R. Ndhlala, J.F. Finnie, and J. Van Staden In vitro Antimicrobial activity of extracts from plants used traditionally in South Africa to treat tuberculosis and related symptoms Evid. Based Complement. Altern. Med. 2013 2013, 1-8 (Article ID 840719).
24. D.M. Maron, and B.N. Ames Revised methods for Salmonella mutagenicity test Mutat. Res. 113 1983 173 215
25. L.J. McGaw, N. Lall, J.J.M. Meyer, and J.N. Eloff The potential of South African plants against Mycobacterium infections J. Ethnopharmacol. 119 2008 482 500
26. K. Mortelmans, and K. Zeiger The Ames Salmonella/Microsome mutagenicity assay Mutat. Res. 455 2000 29 60
27. A.L. Okunade, M.P.F. Elvin-Lewis, and W.H. Lewis Natural antimycobacterial metabolites: current status Phytochemistry 65 2004 1017 1032
28. T. Shinohara, T. Pantuso, S. Shinohara, M. Kogiso, Q.N. Myrvik, R.A. Henriksen, and Y. Shibata Persistent inactivation of macrophage cyclooxygenase-2 in mycobacterial pulmonary inflammation Am. J. Respir. Cell Mol. Biol. 41 2009 146 154
29. G.F. Sibandze, R.L. Van Zyl, and A.N. Viljoen Pharmacological Properties of Swazi Medicinal Plants 2009 University of the Witswatersrand Johannesburg (Thesis)
30. I. Smith Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence Clin. Microbiol. Rev. 16 2003 463 496
31. H. Tunón, C. Olavsdotter, and L. Bohlin Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis J. Ethnopharmacol. 48 1995 61 76
32. L. Verschaeve, and J. Van Staden Mutagenic and antimutagenic properties of extracts from South African traditional medicinal plants J. Ethnopharmacol. 119 2008 575 587
33. World Health Organisation, 2013. Tuberculosis, Fact sheet No. 104.
34. B.T.S. Yff, K.L. Lindsey, M.B. Taylor, D.G. Erasmus, and A.K. Jäger The pharmacological screening of Pentanisia prunelloides and the isolation of the antibacterial compound palmitic acid J. Ethnopharmacol. 79 2002 101 107
35. T. York, S.F. Van Vurren, and H. De Wet An antimicrobial evaluation of plants used for the treatment of respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa J. Ethnopharmacol. 144 2012 118 127
36. E. Zeiger Mutagens that are not carcinogens: faulty theory or faulty tests? Mutat. Res. Genet. Toxicol. Environ. Mutagenesis 492 2001 29 38
37. S. Zschocke, and J. Van Staden Cryptocarya species - substitute plants for Ocotea bullata? A pharmacological investigation in terms of Cyclooxygenase-1 and -2 J. Ethnopharmacol. 71 2000 473 478