-
1
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning, G., Whyte, D. B., Martinez, R., Hunter, T., and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
2
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen, P., and Hunter, T. (2001) Oncogenic kinase signalling. Nature 411, 355-365
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
3
-
-
84859765844
-
Dynamic reprogramming of the kinome in response to targeted mek inhibition in triple-negative breast cancer
-
Duncan, James S., Whittle, Martin C., Nakamura, K., Abell, Amy N., Midland, Alicia A., Zawistowski, Jon S., Johnson, Nancy L., Granger, Deborah A., Jordan, Nicole V., Darr, David B., Usary, J., Kuan, P.-F., Smalley, David M., Major, B., He, X., Hoadley, Katherine A., Zhou, B., Sharpless, Norman E., Perou, Charles M., Kim, William Y., Gomez, Shawn M., Chen, X., Jin, J., Frye, Stephen V., Earp, H. S., Graves, Lee M., and Johnson, Gary L. (2012) Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer. Cell 149, 307-321
-
(2012)
Cell
, vol.149
, pp. 307-321
-
-
Duncan James, S.1
Whittle Martin, C.2
Nakamura, K.3
Abell Amy, N.4
Midland Alicia, A.5
Zawistowski Jon, S.6
Johnson Nancy, L.7
Granger Deborah, A.8
Jordan Nicole, V.9
Darr David, B.10
Usary, J.11
Kuan, P.-F.12
Smalley David, M.13
Major, B.14
He, X.15
Hoadley Katherine, A.16
Zhou, B.17
Sharpless Norman, E.18
Perou Charles, M.19
Kim William, Y.20
Gomez Shawn, M.21
Chen, X.22
Jin, J.23
Frye Stephen, V.24
Earp, H.S.25
Graves Lee, M.26
Johnson Gary, L.27
more..
-
4
-
-
57749188299
-
Targeting cancer with small molecule kinase inhibitors
-
Zhang, J., Yang, P. L., and Gray, N. S. (2009) Targeting cancer with small molecule kinase inhibitors. Nat. Rev. Cancer 9, 28-39
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 28-39
-
-
Zhang, J.1
Yang, P.L.2
Gray, N.S.3
-
5
-
-
38049018155
-
A quantitative analysis of kinase inhibitor selectivity
-
Karaman, M. W., Herrgard, S., Treiber, D. K., Gallant, P., Atteridge, C. E., Campbell, B. T., Chan, K. W., Ciceri, P., Davis, M. I., Edeen, P. T., Faraoni, R., Floyd, M., Hunt, J. P., Lockhart, D. J., Milanov, Z. V., Morrison, M. J., Pallares, G., Patel, H. K., Pritchard, S., Wodicka, L. M., and Zarrinkar, P. P. (2008) A quantitative analysis of kinase inhibitor selectivity. Nat. Biotech. 26, 127-132
-
(2008)
Nat. Biotech
, vol.26
, pp. 127-132
-
-
Karaman, M.W.1
Herrgard, S.2
Treiber, D.K.3
Gallant, P.4
Atteridge, C.E.5
Campbell, B.T.6
Chan, K.W.7
Ciceri, P.8
Davis, M.I.9
Edeen, P.T.10
Faraoni, R.11
Floyd, M.12
Hunt, J.P.13
Lockhart, D.J.14
Milanov, Z.V.15
Morrison, M.J.16
Pallares, G.17
Patel, H.K.18
Pritchard, S.19
Wodicka, L.M.20
Zarrinkar, P.P.21
more..
-
6
-
-
19744365702
-
A small molecule-kinase interaction map for clinical kinase inhibitors
-
Fabian, M. A., Biggs, W. H., Treiber, D. K., Atteridge, C. E., Azimioara, M. D., Benedetti, M. G., Carter, T. A., Ciceri, P., Edeen, P. T., Floyd, M., Ford, J. M., Galvin, M., Gerlach, J. L., Grotzfeld, R. M., Herrgard, S., Insko, D. E., Insko, M. A., Lai, A. G., Lelias, J.-M., Mehta, S. A., Milanov, Z. V., Velasco, A. M., Wodicka, L. M., Patel, H. K., Zarrinkar, P. P., and Lockhart, D. J. (2005) A small molecule-kinase interaction map for clinical kinase inhibitors. Nat. Biotech. 23, 329-336
-
(2005)
Nat. Biotech
, vol.23
, pp. 329-336
-
-
Fabian, M.A.1
Biggs, W.H.2
Treiber, D.K.3
Atteridge, C.E.4
Azimioara, M.D.5
Benedetti, M.G.6
Carter, T.A.7
Ciceri, P.8
Edeen, P.T.9
Floyd, M.10
Ford, J.M.11
Galvin, M.12
Gerlach, J.L.13
Grotzfeld, R.M.14
Herrgard, S.15
Insko, D.E.16
Insko, M.A.17
Lai, A.G.18
Lelias, J.-M.19
Mehta, S.A.20
Milanov, Z.V.21
Velasco, A.M.22
Wodicka, L.M.23
Patel, H.K.24
Zarrinkar, P.P.25
Lockhart, D.J.26
more..
-
7
-
-
80755125575
-
Comprehensive analysis of kinase inhibitor selectivity
-
Davis, M. I., Hunt, J. P., Herrgard, S., Ciceri, P., Wodicka, L. M., Pallares, G., Hocker, M., Treiber, D. K., and Zarrinkar, P. P. (2011) Comprehensive analysis of kinase inhibitor selectivity. Nat. Biotech. 29, 1046-1051
-
(2011)
Nat. Biotech
, vol.29
, pp. 1046-1051
-
-
Davis, M.I.1
Hunt, J.P.2
Herrgard, S.3
Ciceri, P.4
Wodicka, L.M.5
Pallares, G.6
Hocker, M.7
Treiber, D.K.8
Zarrinkar, P.P.9
-
8
-
-
0031055562
-
Detection of anaplastic lymphoma kinase (alk) and nucleolar protein nucleophosmin (npm)-alk proteins in normal and neoplastic cells with the monoclonal antibody alk1
-
Pulford, K., Lamant, L., Morris, S. W., Butler, L. H., Wood, K. M., Stroud, D., Delsol, G., and Mason, D. Y. (1997) Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood 89, 1394-1404
-
(1997)
Blood
, vol.89
, pp. 1394-1404
-
-
Pulford, K.1
Lamant, L.2
Morris, S.W.3
Butler, L.H.4
Wood, K.M.5
Stroud, D.6
Delsol, G.7
Mason, D.Y.8
-
9
-
-
79959424627
-
Quantitative, high-resolution proteomics for data-driven systems biology
-
Cox, J., and Mann, M. (2011) Quantitative, high-resolution proteomics for data-driven systems biology. Annu. Rev. Biochem. 80, 273-299
-
(2011)
Annu. Rev. Biochem
, vol.80
, pp. 273-299
-
-
Cox, J.1
Mann, M.2
-
10
-
-
70549086229
-
Large-scale proteomics analysis of the human kinome
-
Oppermann, F. S., Gnad, F., Olsen, J. V., Hornberger, R., Mann, M., and Daub, H. (2009) Large-scale proteomics analysis of the human kinome. Mol. Cell. Proteomics 8, 1751-1764
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 1751-1764
-
-
Oppermann, F.S.1
Gnad, F.2
Olsen, J.V.3
Hornberger, R.4
Mann, M.5
Daub, H.6
-
11
-
-
84872000716
-
Targeted proteomics
-
Marx, V. (2013) Targeted proteomics. Nat. Meth. 10, 19-22
-
(2013)
Nat. Meth
, vol.10
, pp. 19-22
-
-
Marx, V.1
-
12
-
-
48349138726
-
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle
-
Daub, H., Olsen, J. V., Bairlein, M., Gnad, F., Oppermann, F. S., Stemmann, O., and Mann, M. (2008) Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol. Cell. 31, 438-448
-
(2008)
Mol. Cell
, vol.31
, pp. 438-448
-
-
Daub, H.1
Olsen, J.V.2
Bairlein, M.3
Gnad, F.4
Oppermann, F.S.5
Stemmann, O.6
Mann, M.7
-
13
-
-
84884384717
-
Profiling protein kinases and other atp binding proteins in arabidopsis using acyl-atp probes
-
Villamor, J. G., Kaschani, F., Colby, T., Oeljeklaus, J., Zhao, D., Kaiser, M., Patricelli, M. P., and van der Hoorn, R. A. L. (2013) Profiling protein kinases and other ATP binding proteins in arabidopsis using Acyl-ATP Probes. Mol. Cell. Proteomics 12, 2481-2496
-
(2013)
Mol Cell Proteomics
, vol.12
, pp. 2481-2496
-
-
Villamor, J.G.1
Kaschani, F.2
Colby, T.3
Oeljeklaus, J.4
Zhao, D.5
Kaiser, M.6
Patricelli, M.P.7
Van Der Hoorn, R.A.L.8
-
14
-
-
84872908803
-
Identification of widespread adenosine nucleotide binding in mycobacterium tuberculosis
-
Ansong, C., Ortega, C., Payne, Samuel H., Haft, Daniel H., Chauvigne-Hines, Lacie M., Lewis, Michael P., Ollodart, Anja R., Purvine, Samuel O., Shukla, Anil K., Fortuin, S., Smith, Richard D., Adkins, Joshua N., Grundner, C., and Wright, Aaron T. (2013) Identification of widespread adenosine nucleotide binding in mycobacterium tuberculosis. Chem. Biol. 20, 123-133
-
(2013)
Chem. Biol
, vol.20
, pp. 123-133
-
-
Ansong, C.1
Ortega, C.2
Payne Samuel, H.3
Haft Daniel, H.4
Chauvigne-Hines Lacie, M.5
Lewis Michael, P.6
Ollodart Anja, R.7
Purvine Samuel, O.8
Shukla Anil, K.9
Fortuin, S.10
Smith Richard, D.11
Adkins Joshua, N.12
Grundner, C.13
Wright Aaron, T.14
-
15
-
-
84875434521
-
Proteome-wide discovery and characterizations of nucleotide-binding proteins with affinity-labeled chemical probes
-
Xiao, Y., Guo, L., Jiang, X., and Wang, Y. (2013) Proteome-wide discovery and characterizations of nucleotide-binding proteins with affinity-labeled chemical probes. Anal. Chem. 85, 3198-3206
-
(2013)
Anal. Chem
, vol.85
, pp. 3198-3206
-
-
Xiao, Y.1
Guo, L.2
Jiang, X.3
Wang, Y.4
-
16
-
-
33846248354
-
Functional interrogation of the kinome using nucleotide acyl phosphates
-
Patricelli, M. P., Szardenings, A. K., Liyanage, M., Nomanbhoy, T. K., Wu, M., Weissig, H., Aban, A., Chun, D., Tanner, S., and Kozarich, J. W. Functional interrogation of the kinome using nucleotide acyl phosphates. Biochemistry 46, 350-358
-
Biochemistry
, vol.46
, pp. 350-358
-
-
Patricelli, M.P.1
Szardenings, A.K.2
Liyanage, M.3
Nomanbhoy, T.K.4
Wu, M.5
Weissig, H.6
Aban, A.7
Chun, D.8
Tanner, S.9
Kozarich, J.W.10
-
17
-
-
79959493188
-
In situ kinase profiling reveals functionally relevant properties of native kinases
-
Patricelli, Matthew P., Nomanbhoy, Tyzoon K., Wu, J., Brown, H., Zhou, D., Zhang, J., Jagannathan, S., Aban, A., Okerberg, E., Herring, C., Nordin, B., Weissig, H., Yang, Q., Lee, J.-D., Gray, Nathanael S., and Kozarich, John W. (2011) In situ kinase profiling reveals functionally relevant properties of native kinases. Chem. Biol. 18, 699-710
-
(2011)
Chem. Biol
, vol.18
, pp. 699-710
-
-
Patricelli Matthew, P.1
Nomanbhoy Tyzoon, K.2
Wu, J.3
Brown, H.4
Zhou, D.5
Zhang, J.6
Jagannathan, S.7
Aban, A.8
Okerberg, E.9
Herring, C.10
Nordin, B.11
Weissig, H.12
Yang, Q.13
Lee, J.-D.14
Gray Nathanael, S.15
Kozarich John, W.16
-
18
-
-
75149144996
-
A dual pressure linear ion trap orbitrap instrument with very high sequencing speed
-
Olsen, J. V., Schwartz, J. C., Griep-Raming, J., Nielsen, M. L., Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, M., and Horning, S. (2009) A dual pressure linear ion trap orbitrap instrument with very high sequencing speed. Mol. Cell. Proteomics 8, 2759-2769
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 2759-2769
-
-
Olsen, J.V.1
Schwartz, J.C.2
Griep-Raming, J.3
Nielsen, M.L.4
Damoc, E.5
Denisov, E.6
Lange, O.7
Remes, P.8
Taylor, D.9
Splendore, M.10
Wouters, E.R.11
Senko, M.12
Makarov, A.13
Mann, M.14
Horning, S.15
-
19
-
-
84861990380
-
Selected reaction monitoring-based proteomics: Workflows, potential, pitfalls and future directions
-
Picotti, P., and Aebersold, R. (2012) Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directions. Nat. Meth. 9, 555-566
-
(2012)
Nat. Meth
, vol.9
, pp. 555-566
-
-
Picotti, P.1
Aebersold, R.2
-
20
-
-
54049090766
-
Selected reaction monitoring for quantitative proteomics: A tutorial
-
Lange, V., Picotti, P., Domon, B., and Aebersold, R. (2008) Selected reaction monitoring for quantitative proteomics: a tutorial. Mol. Syst. Biol., 222
-
(2008)
Mol. Syst. Biol
, vol.222
-
-
Lange, V.1
Picotti, P.2
Domon, B.3
Aebersold, R.4
-
21
-
-
84881320082
-
Isotope-coded atp probe for quantitative affinity profiling of atp-binding proteins
-
Xiao, Y., Guo, L., and Wang, Y. (2013) Isotope-coded ATP probe for quantitative affinity profiling of ATP-binding proteins. Anal. Chem. 85, 7478-7486
-
(2013)
Anal. Chem
, vol.85
, pp. 7478-7486
-
-
Xiao, Y.1
Guo, L.2
Wang, Y.3
-
22
-
-
84860869167
-
Using irt, a normalized retention time for more targeted measurement of peptides
-
Escher, C., Reiter, L., MacLean, B., Ossola, R., Herzog, F., Chilton, J., MacCoss, M. J., and Rinner, O. (2012) Using iRT, a normalized retention time for more targeted measurement of peptides. Proteomics 12, 1111-1121
-
(2012)
Proteomics
, vol.12
, pp. 1111-1121
-
-
Escher, C.1
Reiter, L.2
MacLean, B.3
Ossola, R.4
Herzog, F.5
Chilton, J.6
MacCoss, M.J.7
Rinner, O.8
-
23
-
-
77951965920
-
Skyline: An open source document editor for creating and analyzing targeted proteomics experiments
-
MacLean, B., Tomazela, D. M., Shulman, N., Chambers, M., Finney, G. L., Frewen, B., Kern, R., Tabb, D. L., Liebler, D. C., and MacCoss, M. J. (2010) Skyline: an open source document editor for creating and analyzing targeted proteomics experiments. Bioinformatics 26, 966-968
-
(2010)
Bioinformatics
, vol.26
, pp. 966-968
-
-
MacLean, B.1
Tomazela, D.M.2
Shulman, N.3
Chambers, M.4
Finney, G.L.5
Frewen, B.6
Kern, R.7
Tabb, D.L.8
Liebler, D.C.9
MacCoss, M.J.10
-
24
-
-
75749126208
-
Automated detection of inaccurate and imprecise transitions in peptide quantification by multiple reaction monitoring mass spectrometry
-
Abbatiello, S. E., Mani, D. R., Keshishian, H., and Carr, S. A. (2010) Automated detection of inaccurate and imprecise transitions in peptide quantification by multiple reaction monitoring mass spectrometry. Clin. Chem. 56, 291-305
-
(2010)
Clin. Chem
, vol.56
, pp. 291-305
-
-
Abbatiello, S.E.1
Mani, D.R.2
Keshishian, H.3
Carr, S.A.4
-
25
-
-
0141858715
-
The specificity of cross-reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness
-
James, L. C., and Tawfik, D. S. (2003) The specificity of cross-reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness. Protein. Sci. 12, 2183-2193
-
(2003)
Protein. Sci
, vol.12
, pp. 2183-2193
-
-
James, L.C.1
Tawfik, D.S.2
-
26
-
-
0342291188
-
Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (pdgf) and produce a pdgflike growth factor
-
Westermark, B., Johnsson, A., Paulsson, Y., Betsholtz, C., Heldin, C. H., Herlyn, M., Rodeck, U., and Koprowski, H. (1986) Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGFlike growth factor. Proc. Natl. Acad. Sci. U.S.A. 83, 7197-7200
-
(1986)
Proc. Natl. Acad. Sci. U.S.A
, vol.83
, pp. 7197-7200
-
-
Westermark, B.1
Johnsson, A.2
Paulsson, Y.3
Betsholtz, C.4
Heldin, C.H.5
Herlyn, M.6
Rodeck, U.7
Koprowski, H.8
-
27
-
-
79952252166
-
2D-DIGE analysis of phosphoenriched fractions from dasatinib-treated melanoma cell lines
-
Eustace, A. J., Dowling, P., Henry, M., Doolan, P., Meleady, P., Clynes, M., Crown, J., and O'Donovan, N. (2011) 2D-DIGE analysis of phosphoenriched fractions from dasatinib-treated melanoma cell lines. J. Proteomics 74, 490-501
-
(2011)
J. Proteomics
, vol.74
, pp. 490-501
-
-
Eustace, A.J.1
Dowling, P.2
Henry, M.3
Doolan, P.4
Meleady, P.5
Clynes, M.6
Crown, J.7
O'Donovan, N.8
-
28
-
-
0033375469
-
Flavopiridol: The first cyclin-dependent kinase inhibitor in human clinical trials
-
Senderowicz, A. (1999) Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials. Invest. New Drugs 17, 313-320
-
(1999)
Invest. New Drugs
, vol.17
, pp. 313-320
-
-
Senderowicz, A.1
-
29
-
-
33845329203
-
Functional and quantitative proteomics using silac
-
Mann, M. (2006) Functional and quantitative proteomics using SILAC. Nat. Rev. Mol. Cell Biol. 7, 952-958
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
-
-
Mann, M.1
-
30
-
-
0026496223
-
Atp binding to bovine serum albumin
-
Bauer, M., Baumann, J., and Trommer, W. E. (1992) ATP binding to bovine serum albumin. FEBS Lett. 313, 288-290
-
(1992)
FEBS Lett
, vol.313
, pp. 288-290
-
-
Bauer, M.1
Baumann, J.2
Trommer, W.E.3
-
31
-
-
49449126818
-
Atp binding to human hemoglobin in the presence and absence of magnesium ions investigated with 31p nmr spectroscopy and ultrafiltration
-
Costello, A. J. R., Marshall, W. E., Omachi, A., and Henderson, T. O. (1977) ATP binding to human hemoglobin in the presence and absence of magnesium ions investigated with 31P NMR spectroscopy and ultrafiltration. Biochim. Biophys. Acta 491, 469-472
-
(1977)
Biochim. Biophys. Acta
, vol.491
, pp. 469-472
-
-
Costello, A.J.R.1
Marshall, W.E.2
Omachi, A.3
Henderson, T.O.4
-
32
-
-
38349068918
-
Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution
-
Keshishian, H., Addona, T., Burgess, M., Kuhn, E., and Carr, S. A. (2007) Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution. Mol. Cell. Proteomics 6, 2212-2229
-
(2007)
Mol. Cell. Proteomics
, vol.6
-
-
Keshishian, H.1
Addona, T.2
Burgess, M.3
Kuhn, E.4
Carr, S.A.5
-
33
-
-
0036718795
-
Atpases as drug targets: Learning from their structure
-
Chene, P. (2002) ATPases as drug targets: learning from their structure. Nat. Rev. Drug Discov. 1, 665-673
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 665-673
-
-
Chene, P.1
-
34
-
-
84866149676
-
Genomic strategies for personalized cancer therapy
-
Garman, K. S., Nevins, J. R., and Potti, A. (2007) Genomic strategies for personalized cancer therapy. Hum. Mol. Genet. 16, R226-R232
-
(2007)
Hum. Mol. Genet
, vol.16
-
-
Garman, K.S.1
Nevins, J.R.2
Potti, A.3
|