Administration of imatinib mesylate in rats impairs the neonatal development of intramuscular interstitial cells in bladder and results in altered contractile properties

Neurourology and Urodynamics

Volumn 33, Issue 4, 2014, Pages 461-468

  Gevaert, Thomas ^a,b   Hutchings, Graham ^b   Everaerts, Wouter ^a   Prenen, Hans ^c   Roskams, Tania ^b   Nilius, Bernd ^d   De Ridder, Dirk ^a  

^a SKELETAL BIOLOGY AND ENGINEERING RESEARCH CENTER   (Belgium)

^b DEPARTMENT OF IMAGING AND PATHOLOGY   (Belgium)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

bladder; c kit; imatinib mesylate; interstitial cells; muscarinic

Indexed keywords

IMATINIB; STEM CELL FACTOR; VIMENTIN; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE; STEM CELL FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; BLADDER; BLADDER CONTRACTION; CELL COUNT; CELL DAMAGE; CELL MATURATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; NEWBORN; NONHUMAN; PERINATAL DEVELOPMENT; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GROWTH; IN VITRO STUDY; INTERSTITIAL CELL OF CAJAL; MUSCLE CONTRACTION; SMOOTH MUSCLE; TOXICITY; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; BENZAMIDES; FEMALE; GROWTH; IMMUNOHISTOCHEMISTRY; IN VITRO TECHNIQUES; INTERSTITIAL CELLS OF CAJAL; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-KIT; PYRIMIDINES; RATS; RATS, WISTAR; URINARY BLADDER;

EID: 84898745997     PISSN: 07332467     EISSN: 15206777     Source Type: Journal    
DOI: 10.1002/nau.22415     Document Type: Article

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