Imatinib inhibits spontaneous rhythmic contractions of human uterus and intestine

European Journal of Pharmacology

Volumn 546, Issue 1-3, 2006, Pages 177-181

  Popescu, Laurentzio M ^a   Vidulescu, Cristina ^a   Curici, Antoanela ^a   Caravia, Laura ^a   Simionescu, Anca A ^b   Ciontea, Sanda M ^a   Simion, Sorin ^c  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b Philantropy Hospital   (Romania)

^c Carol Davila School of Medicine   (Romania)

Author keywords

c kit CD117; Imatinib (Glivec STI571); Interstitial Cajal like cell; Tyrosine kinase cascade

Indexed keywords

IMATINIB; NORADRENALIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; POTASSIUM ION; PROTEIN TYROSINE KINASE; STEM CELL FACTOR RECEPTOR;

ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL CELL OF CAJAL; INTESTINE CONTRACTION; INTESTINE MUSCLE; MYOMETRIUM; PRIORITY JOURNAL; SMOOTH MUSCLE; UTERUS CONTRACTION;

DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTROINTESTINAL MOTILITY; HUMANS; INTESTINE, SMALL; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-KIT; PYRIMIDINES; UTERINE CONTRACTION; UTERUS;

EID: 33748312077     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.06.068     Document Type: Article

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