Modulation of bladder myofibroblast activity: Implications for bladder function

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 3, 2008, Pages

  Sui, Gui Ping ^a,d   Wu, Changhao ^a,d   Roosen, Alexander ^a   Ikeda, Youko ^b   Kanai, Anthony J ^b   Fry, Christopher H ^a,c,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SURREY   (United Kingdom)

^d UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Purinergic signaling; Spontaneous activity; Suburothelium

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CAPSAICIN; IMATINIB; NITROPRUSSIDE SODIUM; URIDINE TRIPHOSPHATE; CALCIUM; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

ACIDOSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLADDER FUNCTION; BLADDER MUCOSA; CALCIUM CELL LEVEL; CELL ISOLATION; CONTROLLED STUDY; DETRUSOR MUSCLE; DRUG EFFECT; ELECTRIC CAPACITANCE; GUINEA PIG; MALE; MEMBRANE CURRENT; MEMBRANE POTENTIAL; MUSCLE ISOMETRIC CONTRACTION; MUSCLE TONE; MYOFIBROBLAST; NONHUMAN; PH; PRIORITY JOURNAL; SPINAL CORD; ANIMAL; BLADDER; CELL COMMUNICATION; CELL MEMBRANE POTENTIAL; CYTOLOGY; FIBROBLAST; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; RAT; SMOOTH MUSCLE FIBER;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELL COMMUNICATION; FIBROBLASTS; GUINEA PIGS; MALE; MEMBRANE POTENTIALS; MYOCYTES, SMOOTH MUSCLE; PIPERAZINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES; RATS; URINARY BLADDER;

EID: 54449089490     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00133.2008     Document Type: Article

References (32)

1. Biers SM, Reynard JM, Doore T, Brading AF. The functional effects of a c-kit tyrosine inhibitor on guinea-pig and human detrusor. BJU Int 97: 612-616, 2006.
2. Birder LA, Apodaca G, De Groat WC, Kanai AJ. Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder. Am J Physiol Renal Physiol 275: F226-F229, 1998.
3. Brunton VG, MacPherson IR, Frame MC. Cell adhesion receptors, tyrosine kinases and actin modulators: a complex three-way circuitry. Biochim Biophys Acta 1692: 121-144, 2004.
4. Caterina M, Schumacher M, Tominaga M, Rosen T, Levine J, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824, 1997.
5. Cavallaro U, Niedermeyer J, Fuxa M, Christofori G. N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling. Nat Cell Biol 3: 650-657 2001.
6. Cockayne DA, Hamilton SG, Zhu QM, Dunn PM, Zhong Y, Novakovic S, Malmberg AB, Cain G, Berson A, Kassotakis L, Hedley L, Lachnit WG, Burnstock G, McMahon SB, Ford AP. Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature 407: 1011-1015, 2000.
7. Contreras RG, Shoshani L, Flores-Maldonado C, Lazaro A, Monroy AO, Roldan ML, Fiorentino R, Cereijido M. E-Cadherin and tight junctions between epithelial cells of different animal species. Pflügers Arch 444: 467-475, 2002.
8. Cruz F. Mechanisms involved in new therapies for overactive bladder. Urology 63, Suppl 1: 65-73, 2004.
9. Davidson RA, McCloskey KD. Morphology and localization of interstitial cells in the guinea pig bladder: structural relationships with smooth muscle and neurons. J Urol 173: 1385-1390, 2005.
10. Ferguson DR, Kennedy I, Burton TJ. ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? J Physiol 505: 503-511, 1997.
11. Gillespie JI, Ittersum MMV, De Vente J. Endogenous nitric oxide/cGMP signalling in the guinea pig bladder: evidence for distinct populations of sub-urothelial interstitial cells. Cell Tissue Res 325: 325-332. 2006.
12. Ikeda Y, Fry CH, Hayashi F, Stolz DB, Griffiths D, Kanai AJ. The role of gap junctions in spontaneous activity of the rat bladder. Am J Physiol Renal Physiol 293: F1018-F1025, 2007.
13. Kanai A, Roppolo J, Ikeda Y, Zabbarova I, Tai C, Birder L, Griffiths D, de Groat W, Fry C. Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists. Am J Physiol Renal Physiol 292: F1065-F1072, 2007.
14. 2+-tyrosine kinase-Erk1/2 pathway. J Cardiovasc Pharmacol 45: 418-430, 2005.
15. Knight GE, Bodin P, De Groat WC, Burnstock G. ATP is released from guinea pig ureter epithelium on distension. Am J Physiol Renal Physiol 282: F281-F288, 2002.
16. Kruse MN, Bray LA, de Groat WC. Influence of spinal cord injury on the morphology of bladder afferent and efferent neurons. J Autonom Nerv Syst 54: 215-224, 1995.
17. Kubota Y, Biers SM, Kohri K, Brading AF. Effects of imatinib mesylate (Glivec) as a c-kit tyr-osine kinase inhibitor in the guinea-pig urinary bladder. Neurourol Urodyn 25: 205-210, 2006.
18. Kuijpers KA, Heesakkers JP, Jansen CF, Schalken JA. Cadherin-11 is expressed in detrusor smooth muscle cells and myofibroblasts of normal human bladder. Eur Urol 52: 1213-1221, 2007.
19. Montgomery BS, Fry CH. The action potential and net membrane currents in isolated human detrusor smooth muscle cells. J Urol 147: 176-184, 1992.
20. Mukerji G, Yiangou Y, Agarwal SK, Anand P. Transient receptor potential vanilloid receptor subtype 1 in painful bladder syndrome and its correlation with pain. J Urol 176: 797-801, 2006.
21. Ost D, Roskams T, Van Der Aa F, De Ridder D. Topography of the vanilloid receptor in the human bladder: more than just the nerve fibers. J Urol 168: 293-297, 2002.
22. Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 50: 413-492, 1998.
23. Reber L, Da Silva CA, Frossard N. Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eur J Pharmacol 533: 327-340, 2006.
24. Roskoski R Jr. Signaling by Kit protein-tyrosine kinase-the stem cell factor receptor. Biochem Biophys Res Commun; 337: 1-13, 2005.
25. Smet PJ, Jonavicius J, Marshall VR, De Vente J. Distribution of nitric oxide synthase-immunoreactive nerves, and identification of the cellular targets of nitric oxide in guinea-pig and human urinary bladder by cGMP immunohistochemistry. Neuroscience 71: 337-348, 1996.
26. Sui GP, Rothery S, Dupont E, Fry CH, Severs NJ. Gap junctions and connexin expression in human suburothelial interstitial cells. BJU Int 90: 118-129, 2002.
27. Sui GP, Wu C, Fry CH. Characterization of the purinergic receptor subtype on guinea-pig suburothelial myofibroblasts. BJU Int 97: 1327-1331, 2006.
28. Szallasi A, Fowler CJ. After a decade of intravesical vanilloid therapy: still more questions than answers. Lancet Neurol 1: 167-172, 2002.
29. Vlaskovska M, Kasakov L, Rong W, Bodin P, Bardini M, Cockayne DA, Ford AP, Burnstock G. P2X3 knock-out mice reveal a major sensory role for urothelially released ATP. J Neurosci 21: 5670-5677, 2001.
30. Wiseman OJ, Fowler CJ, Landon DN. The role of the human bladder lamina propria myofibroblast. BJU Int 91: 89-93, 2003.
31. 2+ regulation in guinea pig detrusor smooth muscle. Am J Physiol Cell Physiol 280: C1090-C1096, 2001.
32. Wu C, Sui GP, Fry CH. Purinergic regulation of guinea pig suburothelial myofibroblasts. J Physiol 559: 231-243, 2004.