Characterization of plasmodium falciparum calcium-dependent protein kinase 1 (PFCDPK1) and its role in microneme secretion during erythrocyte invasion

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1590-1602

  Bansal, Abhisheka ^a   Singh, Shailja ^a   More, Kunal R ^a   Hans, Dhiraj ^a   Nangalia, Kuldeep ^a   Yogavel, Manickam ^a   Sharma, Amit ^a   Chitnis, Chetan E ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY ICGEB   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APICOMPLEXAN PARASITES; CALCIUM BINDING; CALCIUM DEPENDENT PROTEIN KINASE; DRUG DEVELOPMENT; EF-HAND; FUNCTIONAL ACTIVITIES; HYDROPHOBIC RESIDUES; KEY PROCESS; KINASE ACTIVITY; KINASE DOMAINS; MALARIA PARASITE; MODELING STUDIES; N-TERMINALS; PARASITE GROWTH; PLASMODIUM FALCIPARUM; POTENTIAL TARGETS; SITE DIRECTED MUTAGENESIS; SPECIFIC INHIBITORS;

DISEASES; ENZYME ACTIVITY; PEPTIDES; PLANTS (BOTANY);

BLOOD;

CALCIUM DEPENDENT PROTEIN KINASE 1; CALCIUM ION; CALMODULIN; LEUCINE; P3 PEPTIDE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PURFALCAMINE; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL INVASION; CELLULAR SECRETION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ANALYSIS; ERYTHROCYTE; HOST PARASITE INTERACTION; HYDROPHOBICITY; MALARIA; MEROZOITE; MICRONEME SECRETION; MOLECULAR INTERACTION; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ADENINE; AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CALCIUM; CALMODULIN; CYCLOHEXYLAMINES; ERYTHROCYTES; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; MEROZOITES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; ORGANELLES; PEPTIDES; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS;

PLASMODIUM FALCIPARUM; TOXOPLASMA;

EID: 84872721370     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.411934     Document Type: Article

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