Rifampicin protects PC12 cells from rotenone-induced cytotoxicity by activating GRP78 via PERK-eIF2α-ATF4 pathway

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Jing, Xiuna ^a   Shi, Qiaoyun ^b   Bi, Wei ^a,c   Zeng, Zhifen ^a   Liang, Yanran ^a   Wu, Xia ^a   Xiao, Songhua ^a   Liu, Jun ^a   Yang, Lianhong ^a   Tao, Enxiang ^a  

^a SUN YAT SEN MEMORIAL HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING KINASE ALPHA; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; RIFAMPICIN; ROTENONE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; NEUROPROTECTION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; CELL DEATH; DNA-BINDING PROTEINS; EIF-2 KINASE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDORIBONUCLEASES; EUKARYOTIC INITIATION FACTOR-2; HEAT-SHOCK PROTEINS; NEUROPROTECTIVE AGENTS; PC12 CELLS; RATS; RIFAMPIN; ROTENONE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84898669701     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092110     Document Type: Article

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