Formulation and optimization of a novel oral fast dissolving film containing drug nanoparticles by Box-Behnken design-response surface methodology

Drug Development and Industrial Pharmacy

Volumn 40, Issue 5, 2014, Pages 649-656

  Shen, Chengying ^a,b   Shen, Baode ^a,c   Xu, He ^a,b   Bai, Jinxia ^a,b   Dai, Ling ^a,b   Lv, Qingyuan ^a   Han, Jin ^a   Yuan, Hailong ^a  

^a BEIJING 302 HOSPITAL   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Box Behnken design; Casting; High pressure homogenization; Nanosuspensions; Oral fast dissolving film

Indexed keywords

ANTIVIRUS AGENT; HERPETRIONE; NANOFILM; NANOPARTICLE; UNCLASSIFIED DRUG; WATER; FURAN DERIVATIVE;

ADHESION; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; IN VITRO STUDY; PARTICLE SIZE; RESPONSE SURFACE METHOD; SCANNING ELECTRON MICROSCOPY; X RAY; ZETA POTENTIAL; BIOLOGICAL MODEL; DRUG DELIVERY SYSTEM; HUMAN; MEDICINAL CHEMISTRY; ORAL DRUG ADMINISTRATION; SOLUBILITY; SURFACE PROPERTY; ULTRASTRUCTURE;

ADMINISTRATION, ORAL; ANTIVIRAL AGENTS; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; FURANS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MODELS, BIOLOGICAL; NANOPARTICLES; PARTICLE SIZE; SOLUBILITY; SURFACE PROPERTIES;

EID: 84898646575     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2014.884116     Document Type: Article

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