메뉴 건너뛰기




Volumn 269, Issue , 2014, Pages 79-92

Dual orexin receptor antagonist 12 inhibits expression of proteins in neurons and glia implicated in peripheral and central sensitization

Author keywords

Nociception; Orexin; Orexin receptor antagonist; Pain; Trigeminal nerve

Indexed keywords

ACTIN BINDING PROTEIN; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AIF1 PROTEIN, RAT; AZEPINE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; CALCIUM BINDING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DORA-12; FREUND ADJUVANT; HCRTR1 PROTEIN, RAT; HCRTR2 PROTEIN, RAT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OREXIN RECEPTOR;

EID: 84898645016     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.03.043     Document Type: Article
Times cited : (43)

References (66)
  • 2
    • 44849139322 scopus 로고    scopus 로고
    • Meta-analysis of treatment need for temporomandibular disorders in adult nonpatients
    • Al-Jundi M.A., John M.T., Setz J.M., Szentpetery A., Kuss O. Meta-analysis of treatment need for temporomandibular disorders in adult nonpatients. J Orofac Pain 2008, 22:97-107.
    • (2008) J Orofac Pain , vol.22 , pp. 97-107
    • Al-Jundi, M.A.1    John, M.T.2    Setz, J.M.3    Szentpetery, A.4    Kuss, O.5
  • 3
    • 2442558400 scopus 로고    scopus 로고
    • Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area
    • Bartsch T., Levy M.J., Knight Y.E., Goadsby P.J. Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area. Pain 2004, 109:367-378.
    • (2004) Pain , vol.109 , pp. 367-378
    • Bartsch, T.1    Levy, M.J.2    Knight, Y.E.3    Goadsby, P.J.4
  • 4
    • 77955006504 scopus 로고    scopus 로고
    • Central neuron-glia interactions and neuropathic pain: overview of recent concepts and clinical implications
    • Benarroch E.E. Central neuron-glia interactions and neuropathic pain: overview of recent concepts and clinical implications. Neurology 2010, 75:273-278.
    • (2010) Neurology , vol.75 , pp. 273-278
    • Benarroch, E.E.1
  • 6
    • 77953134116 scopus 로고    scopus 로고
    • Cocoa-enriched diets enhance expression of phosphatases and decrease expression of inflammatory molecules in trigeminal ganglion neurons
    • Cady R.J., Durham P.L. Cocoa-enriched diets enhance expression of phosphatases and decrease expression of inflammatory molecules in trigeminal ganglion neurons. Brain Res 2010, 1323:18-32.
    • (2010) Brain Res , vol.1323 , pp. 18-32
    • Cady, R.J.1    Durham, P.L.2
  • 7
    • 82655162516 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization
    • Cady R.J., Glenn J.R., Smith K.M., Durham P.L. Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization. Mol Pain 2011, 7:94.
    • (2011) Mol Pain , vol.7 , pp. 94
    • Cady, R.J.1    Glenn, J.R.2    Smith, K.M.3    Durham, P.L.4
  • 8
    • 78650824596 scopus 로고    scopus 로고
    • Dietary grape seed polyphenols repress neuron and glia activation in trigeminal ganglion and trigeminal nucleus caudalis
    • Cady R.J., Hirst J.J., Durham P.L. Dietary grape seed polyphenols repress neuron and glia activation in trigeminal ganglion and trigeminal nucleus caudalis. Mol Pain 2010, 6:91.
    • (2010) Mol Pain , vol.6 , pp. 91
    • Cady, R.J.1    Hirst, J.J.2    Durham, P.L.3
  • 11
    • 79952946685 scopus 로고    scopus 로고
    • Discovery of dual orexin receptor antagonists (DORAs) for the treatment of insomnia
    • Coleman P.J., Cox C.D., Roecker A.J. Discovery of dual orexin receptor antagonists (DORAs) for the treatment of insomnia. Curr Top Med Chem 2011, 11:696-725.
    • (2011) Curr Top Med Chem , vol.11 , pp. 696-725
    • Coleman, P.J.1    Cox, C.D.2    Roecker, A.J.3
  • 12
    • 77649157819 scopus 로고    scopus 로고
    • Orexin receptor antagonists: a review of promising compounds patented since 2006
    • Coleman P.J., Renger J.J. Orexin receptor antagonists: a review of promising compounds patented since 2006. Expert Opin Ther Pat 2010, 20:307-324.
    • (2010) Expert Opin Ther Pat , vol.20 , pp. 307-324
    • Coleman, P.J.1    Renger, J.J.2
  • 14
    • 0036758662 scopus 로고    scopus 로고
    • Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization
    • Dai Y., Iwata K., Fukuoka T., Kondo E., Tokunaga A., Yamanaka H., Tachibana T., Liu Y., Noguchi K. Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization. J Neurosci 2002, 22:7737-7745.
    • (2002) J Neurosci , vol.22 , pp. 7737-7745
    • Dai, Y.1    Iwata, K.2    Fukuoka, T.3    Kondo, E.4    Tokunaga, A.5    Yamanaka, H.6    Tachibana, T.7    Liu, Y.8    Noguchi, K.9
  • 15
    • 77953780135 scopus 로고    scopus 로고
    • Painful neuron-microglia interactions in the trigeminal sensory system
    • Davies A.J., Kim Y.H., Oh S.B. Painful neuron-microglia interactions in the trigeminal sensory system. Open Pain J 2010, 14-28.
    • (2010) Open Pain J , pp. 14-28
    • Davies, A.J.1    Kim, Y.H.2    Oh, S.B.3
  • 17
    • 1642579573 scopus 로고    scopus 로고
    • Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia
    • DeLeo J.A., Tanga F.Y., Tawfik V.L. Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist 2004, 10:40-52.
    • (2004) Neuroscientist , vol.10 , pp. 40-52
    • DeLeo, J.A.1    Tanga, F.Y.2    Tawfik, V.L.3
  • 18
    • 34249730948 scopus 로고    scopus 로고
    • Satellite glial cells in sensory ganglia: their possible contribution to inflammatory pain
    • Dublin P., Hanani M. Satellite glial cells in sensory ganglia: their possible contribution to inflammatory pain. Brain Behav Immun 2007, 21:592-598.
    • (2007) Brain Behav Immun , vol.21 , pp. 592-598
    • Dublin, P.1    Hanani, M.2
  • 19
    • 0025427107 scopus 로고
    • Assessing clinical signs of temporomandibular disorders: reliability of clinical examiners
    • Dworkin S.F., LeResche L., DeRouen T., Von Korff M. Assessing clinical signs of temporomandibular disorders: reliability of clinical examiners. J Prosthet Dent 1990, 63:574-579.
    • (1990) J Prosthet Dent , vol.63 , pp. 574-579
    • Dworkin, S.F.1    LeResche, L.2    DeRouen, T.3    Von Korff, M.4
  • 20
    • 84872303333 scopus 로고    scopus 로고
    • TNFalpha levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine
    • Franceschini A., Vilotti S., Ferrari M.D., van den Maagdenberg A.M., Nistri A., Fabbretti E. TNFalpha levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine. PLoS ONE 2013, 8:e52394.
    • (2013) PLoS ONE , vol.8
    • Franceschini, A.1    Vilotti, S.2    Ferrari, M.D.3    van den Maagdenberg, A.M.4    Nistri, A.5    Fabbretti, E.6
  • 21
    • 74549130005 scopus 로고    scopus 로고
    • C-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?
    • Gao Y.J., Ji R.R. C-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?. Open Pain J 2009, 2:11-17.
    • (2009) Open Pain J , vol.2 , pp. 11-17
    • Gao, Y.J.1    Ji, R.R.2
  • 22
    • 77953131930 scopus 로고    scopus 로고
    • Differential expression of connexins in trigeminal ganglion neurons and satellite glial cells in response to chronic or acute joint inflammation
    • Garrett F.G., Durham P.L. Differential expression of connexins in trigeminal ganglion neurons and satellite glial cells in response to chronic or acute joint inflammation. Neuron Glia Biol 2009, 1-12.
    • (2009) Neuron Glia Biol , pp. 1-12
    • Garrett, F.G.1    Durham, P.L.2
  • 23
    • 84871867690 scopus 로고    scopus 로고
    • Validation of a novel rat-holding device for studying heat- and mechanical-evoked trigeminal nocifensive behavioral responses
    • Garrett F.G., Hawkins J.L., Overmyer A.E., Hayden J.B., Durham P.L. Validation of a novel rat-holding device for studying heat- and mechanical-evoked trigeminal nocifensive behavioral responses. J Orofac Pain 2012, 26:337-344.
    • (2012) J Orofac Pain , vol.26 , pp. 337-344
    • Garrett, F.G.1    Hawkins, J.L.2    Overmyer, A.E.3    Hayden, J.B.4    Durham, P.L.5
  • 24
    • 84930481666 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXXVI. Orexin receptor function, nomenclature and pharmacology
    • Gotter A.L., Webber A.L., Coleman P.J., Renger J.J., Winrow C.J. International Union of Basic and Clinical Pharmacology. LXXXVI. Orexin receptor function, nomenclature and pharmacology. Pharmacol Rev 2012, 64:389-420.
    • (2012) Pharmacol Rev , vol.64 , pp. 389-420
    • Gotter, A.L.1    Webber, A.L.2    Coleman, P.J.3    Renger, J.J.4    Winrow, C.J.5
  • 26
    • 33751331724 scopus 로고    scopus 로고
    • Temporomandibular joint pain and dysfunctioning
    • Herb K., Cho S., Stiles M. Temporomandibular joint pain and dysfunctioning. Curr Pain Headache Rep 2006, 10:408-414.
    • (2006) Curr Pain Headache Rep , vol.10 , pp. 408-414
    • Herb, K.1    Cho, S.2    Stiles, M.3
  • 27
    • 27744547515 scopus 로고    scopus 로고
    • Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception
    • Holland P.R., Akerman S., Goadsby P.J. Orexin 1 receptor activation attenuates neurogenic dural vasodilation in an animal model of trigeminovascular nociception. J Pharmacol Exp Ther 2005, 315:1380-1385.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1380-1385
    • Holland, P.R.1    Akerman, S.2    Goadsby, P.J.3
  • 28
    • 33751359446 scopus 로고    scopus 로고
    • Modulation of nociceptive dural input to the trigeminal nucleus caudalis via activation of the orexin 1 receptor in the rat
    • Holland P.R., Akerman S., Goadsby P.J. Modulation of nociceptive dural input to the trigeminal nucleus caudalis via activation of the orexin 1 receptor in the rat. Eur J Neurosci 2006, 24:2825-2833.
    • (2006) Eur J Neurosci , vol.24 , pp. 2825-2833
    • Holland, P.R.1    Akerman, S.2    Goadsby, P.J.3
  • 29
    • 34547223044 scopus 로고    scopus 로고
    • Signaling pathways in sensitization: toward a nociceptor cell biology
    • Hucho T., Levine J.D. Signaling pathways in sensitization: toward a nociceptor cell biology. Neuron 2007, 55:365-376.
    • (2007) Neuron , vol.55 , pp. 365-376
    • Hucho, T.1    Levine, J.D.2
  • 30
    • 84862208225 scopus 로고    scopus 로고
    • Contribution of microglia and astrocytes to the central sensitization, inflammatory and neuropathic pain in the juvenile rat
    • Ikeda H., Kiritoshi T., Murase K. Contribution of microglia and astrocytes to the central sensitization, inflammatory and neuropathic pain in the juvenile rat. Mol Pain 2012, 8:43.
    • (2012) Mol Pain , vol.8 , pp. 43
    • Ikeda, H.1    Kiritoshi, T.2    Murase, K.3
  • 31
    • 59049107761 scopus 로고    scopus 로고
    • Temporomandibular joint and muscle disorder-type pain in U.S. adults: the National Health Interview Survey
    • Isong U., Gansky S.A., Plesh O. Temporomandibular joint and muscle disorder-type pain in U.S. adults: the National Health Interview Survey. J Orofac Pain 2008, 22:317-322.
    • (2008) J Orofac Pain , vol.22 , pp. 317-322
    • Isong, U.1    Gansky, S.A.2    Plesh, O.3
  • 32
    • 4444312555 scopus 로고    scopus 로고
    • Peripheral and central mechanisms of inflammatory pain, with emphasis on MAP kinases
    • Ji R.R. Peripheral and central mechanisms of inflammatory pain, with emphasis on MAP kinases. Curr Drug Targets Inflamm Allergy 2004, 3:299-303.
    • (2004) Curr Drug Targets Inflamm Allergy , vol.3 , pp. 299-303
    • Ji, R.R.1
  • 34
    • 68949189686 scopus 로고    scopus 로고
    • Central sensitization: a generator of pain hypersensitivity by central neural plasticity
    • Latremoliere A., Woolf C.J. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain 2009, 10:895-926.
    • (2009) J Pain , vol.10 , pp. 895-926
    • Latremoliere, A.1    Woolf, C.J.2
  • 35
    • 0036120527 scopus 로고    scopus 로고
    • Comparative analysis of the chemical neuroanatomy of the mammalian trigeminal ganglion and mesencephalic trigeminal nucleus
    • Lazarov N.E. Comparative analysis of the chemical neuroanatomy of the mammalian trigeminal ganglion and mesencephalic trigeminal nucleus. Prog Neurobiol 2002, 66:19-59.
    • (2002) Prog Neurobiol , vol.66 , pp. 19-59
    • Lazarov, N.E.1
  • 36
    • 84876741388 scopus 로고    scopus 로고
    • Neurotransmitters and microglial-mediated neuroinflammation
    • Lee M. Neurotransmitters and microglial-mediated neuroinflammation. Curr Protein Pept Sci 2013, 14:21-32.
    • (2013) Curr Protein Pept Sci , vol.14 , pp. 21-32
    • Lee, M.1
  • 38
    • 84876932335 scopus 로고    scopus 로고
    • Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status
    • Mieda M., Sakurai T. Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status. CNS Drugs 2013, 27:83-90.
    • (2013) CNS Drugs , vol.27 , pp. 83-90
    • Mieda, M.1    Sakurai, T.2
  • 39
    • 79951670500 scopus 로고    scopus 로고
    • Expression and localization of the orexin-1 receptor (OX1R) after traumatic brain injury in mice
    • Mihara Y., Dohi K., Yofu S., Nakamachi T., Ohtaki H., Shioda S., Aruga T. Expression and localization of the orexin-1 receptor (OX1R) after traumatic brain injury in mice. J Mol Neurosci 2011, 43:162-168.
    • (2011) J Mol Neurosci , vol.43 , pp. 162-168
    • Mihara, Y.1    Dohi, K.2    Yofu, S.3    Nakamachi, T.4    Ohtaki, H.5    Shioda, S.6    Aruga, T.7
  • 40
    • 79955579165 scopus 로고    scopus 로고
    • Glutamate pharmacology and metabolism in peripheral primary afferents: physiological and pathophysiological mechanisms
    • Miller K.E., Hoffman E.M., Sutharshan M., Schechter R. Glutamate pharmacology and metabolism in peripheral primary afferents: physiological and pathophysiological mechanisms. Pharmacol Ther 2011, 130:283-309.
    • (2011) Pharmacol Ther , vol.130 , pp. 283-309
    • Miller, K.E.1    Hoffman, E.M.2    Sutharshan, M.3    Schechter, R.4
  • 42
    • 57749200564 scopus 로고    scopus 로고
    • Pathological and protective roles of glia in chronic pain
    • Milligan E.D., Watkins L.R. Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci 2009, 10:23-36.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 23-36
    • Milligan, E.D.1    Watkins, L.R.2
  • 43
    • 84859904538 scopus 로고    scopus 로고
    • The effect of minocycline on the masticatory movements following the inferior alveolar nerve transection in freely moving rats
    • Mostafeezur R.M., Zakir H.M., Yamada Y., Yamamura K., Iwata K., Sessle B.J., Kitagawa J. The effect of minocycline on the masticatory movements following the inferior alveolar nerve transection in freely moving rats. Mol Pain 2012, 8:27.
    • (2012) Mol Pain , vol.8 , pp. 27
    • Mostafeezur, R.M.1    Zakir, H.M.2    Yamada, Y.3    Yamamura, K.4    Iwata, K.5    Sessle, B.J.6    Kitagawa, J.7
  • 44
    • 79951652761 scopus 로고    scopus 로고
    • Spinal astrocytes as therapeutic targets for pathological pain
    • Nakagawa T., Kaneko S. Spinal astrocytes as therapeutic targets for pathological pain. J Pharmacol Sci 2010, 114:347-353.
    • (2010) J Pharmacol Sci , vol.114 , pp. 347-353
    • Nakagawa, T.1    Kaneko, S.2
  • 45
    • 84876469843 scopus 로고    scopus 로고
    • Availability of a microglia and macrophage marker, iba-1, for differential diagnosis of spontaneous malignant reticuloses from astrocytomas in rats
    • Nakamura R., Nishimura T., Ochiai T., Nakada S., Nagatani M., Ogasawara H. Availability of a microglia and macrophage marker, iba-1, for differential diagnosis of spontaneous malignant reticuloses from astrocytomas in rats. J Toxicol Pathol 2013, 26:55-60.
    • (2013) J Toxicol Pathol , vol.26 , pp. 55-60
    • Nakamura, R.1    Nishimura, T.2    Ochiai, T.3    Nakada, S.4    Nagatani, M.5    Ogasawara, H.6
  • 47
    • 84892798755 scopus 로고    scopus 로고
    • Minocycline attenuates mechanical allodynia and expression of spinal NMDA receptor 1 subunit in rat neuropathic pain model
    • Pu S., Xu Y., Du D., Yang M., Zhang X., Wu J., Jiang W. Minocycline attenuates mechanical allodynia and expression of spinal NMDA receptor 1 subunit in rat neuropathic pain model. J Physiol Biochem 2013, 69:349-357.
    • (2013) J Physiol Biochem , vol.69 , pp. 349-357
    • Pu, S.1    Xu, Y.2    Du, D.3    Yang, M.4    Zhang, X.5    Wu, J.6    Jiang, W.7
  • 48
    • 41649108290 scopus 로고    scopus 로고
    • Hypocretins and primary headaches: neurobiology and clinical implications
    • Rainero I., De Martino P., Pinessi L. Hypocretins and primary headaches: neurobiology and clinical implications. Expert Rev Neurother 2008, 8:409-416.
    • (2008) Expert Rev Neurother , vol.8 , pp. 409-416
    • Rainero, I.1    De Martino, P.2    Pinessi, L.3
  • 49
    • 81255166631 scopus 로고    scopus 로고
    • Neuron, glia and reciprocal relationships in pain processing
    • Ren K. Neuron, glia and reciprocal relationships in pain processing. Open Pain J 2009, 2:7-31.
    • (2009) Open Pain J , vol.2 , pp. 7-31
    • Ren, K.1
  • 51
    • 18244387226 scopus 로고    scopus 로고
    • Peripheral and central mechanisms of orofacial pain and their clinical correlates
    • Sessle B.J. Peripheral and central mechanisms of orofacial pain and their clinical correlates. Minerva Anestesiol 2005, 71:117-136.
    • (2005) Minerva Anestesiol , vol.71 , pp. 117-136
    • Sessle, B.J.1
  • 52
    • 79959594853 scopus 로고    scopus 로고
    • Peripheral and central mechanisms of orofacial inflammatory pain
    • Sessle B.J. Peripheral and central mechanisms of orofacial inflammatory pain. Int Rev Neurobiol 2011, 97:179-206.
    • (2011) Int Rev Neurobiol , vol.97 , pp. 179-206
    • Sessle, B.J.1
  • 53
    • 70349934573 scopus 로고    scopus 로고
    • The role of peptides in central sensitization
    • Seybold V.S. The role of peptides in central sensitization. Handb Exp Pharmacol 2009, 451-491.
    • (2009) Handb Exp Pharmacol , pp. 451-491
    • Seybold, V.S.1
  • 54
    • 33845484856 scopus 로고    scopus 로고
    • Overview of orofacial pain: epidemiology and gender differences in orofacial pain
    • Shinal R.M., Fillingim R.B. Overview of orofacial pain: epidemiology and gender differences in orofacial pain. Dent Clin North Am 2007, 51:1-18.
    • (2007) Dent Clin North Am , vol.51 , pp. 1-18
    • Shinal, R.M.1    Fillingim, R.B.2
  • 55
    • 0034667721 scopus 로고    scopus 로고
    • The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding
    • Sutcliffe J.G., de Lecea L. The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding. J Neurosci Res 2000, 62:161-168.
    • (2000) J Neurosci Res , vol.62 , pp. 161-168
    • Sutcliffe, J.G.1    de Lecea, L.2
  • 56
    • 34547936356 scopus 로고    scopus 로고
    • Phosphorylation of ERK in trigeminal spinal nucleus neurons following passive jaw movement in rats with chronic temporomandibular joint inflammation
    • Suzuki I., Harada T., Asano M., Tsuboi Y., Kondo M., Gionhaku N., Kitagawa J., Kusama T., Iwata K. Phosphorylation of ERK in trigeminal spinal nucleus neurons following passive jaw movement in rats with chronic temporomandibular joint inflammation. J Orofac Pain 2007, 21:225-231.
    • (2007) J Orofac Pain , vol.21 , pp. 225-231
    • Suzuki, I.1    Harada, T.2    Asano, M.3    Tsuboi, Y.4    Kondo, M.5    Gionhaku, N.6    Kitagawa, J.7    Kusama, T.8    Iwata, K.9
  • 57
    • 68049083543 scopus 로고    scopus 로고
    • Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected]
    • Thompson W.L., Van Eldik L.J. Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected]. Brain Res 2009, 1287:47-57.
    • (2009) Brain Res , vol.1287 , pp. 47-57
    • Thompson, W.L.1    Van Eldik, L.J.2
  • 58
    • 33847313564 scopus 로고    scopus 로고
    • An operant conditioning model to assess changes in feeding behavior associated with temporomandibular joint inflammation in the rat
    • Thut P.D., Hermanstyne T.O., Flake N.M., Gold M.S. An operant conditioning model to assess changes in feeding behavior associated with temporomandibular joint inflammation in the rat. J Orofac Pain 2007, 21:7-18.
    • (2007) J Orofac Pain , vol.21 , pp. 7-18
    • Thut, P.D.1    Hermanstyne, T.O.2    Flake, N.M.3    Gold, M.S.4
  • 59
    • 67349164309 scopus 로고    scopus 로고
    • Mode of action of cytokines on nociceptive neurons
    • Uceyler N., Schafers M., Sommer C. Mode of action of cytokines on nociceptive neurons. Exp Brain Res 2009, 196:67-78.
    • (2009) Exp Brain Res , vol.196 , pp. 67-78
    • Uceyler, N.1    Schafers, M.2    Sommer, C.3
  • 61
    • 78650865137 scopus 로고    scopus 로고
    • Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus
    • Villa G., Ceruti S., Zanardelli M., Magni G., Jasmin L., Ohara P.T., Abbracchio M.P. Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. Mol Pain 2010, 6:89.
    • (2010) Mol Pain , vol.6 , pp. 89
    • Villa, G.1    Ceruti, S.2    Zanardelli, M.3    Magni, G.4    Jasmin, L.5    Ohara, P.T.6    Abbracchio, M.P.7
  • 62
    • 84891278444 scopus 로고    scopus 로고
    • Discovery and development of orexin receptor antagonists as therapeutics for insomnia
    • Winrow C.J., Renger J.J. Discovery and development of orexin receptor antagonists as therapeutics for insomnia. Br J Pharmacol 2013.
    • (2013) Br J Pharmacol
    • Winrow, C.J.1    Renger, J.J.2
  • 63
    • 80051512547 scopus 로고    scopus 로고
    • Activation of orexin/hypocretin type 1 receptors stimulates cAMP synthesis in primary cultures of rat astrocytes
    • Woldan-Tambor A., Bieganska K., Wiktorowska-Owczarek A., Zawilska J.B. Activation of orexin/hypocretin type 1 receptors stimulates cAMP synthesis in primary cultures of rat astrocytes. Pharmacol Rep 2011, 63:717-723.
    • (2011) Pharmacol Rep , vol.63 , pp. 717-723
    • Woldan-Tambor, A.1    Bieganska, K.2    Wiktorowska-Owczarek, A.3    Zawilska, J.B.4
  • 64
    • 44849087993 scopus 로고    scopus 로고
    • Glial involvement in trigeminal central sensitization
    • Xie Y.F. Glial involvement in trigeminal central sensitization. Acta Pharmacol Sin 2008, 29:641-645.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 641-645
    • Xie, Y.F.1
  • 65
    • 34249706333 scopus 로고    scopus 로고
    • Involvement of glia in central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn)
    • Xie Y.F., Zhang S., Chiang C.Y., Hu J.W., Dostrovsky J.O., Sessle B.J. Involvement of glia in central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn). Brain Behav Immun 2007, 21:634-641.
    • (2007) Brain Behav Immun , vol.21 , pp. 634-641
    • Xie, Y.F.1    Zhang, S.2    Chiang, C.Y.3    Hu, J.W.4    Dostrovsky, J.O.5    Sessle, B.J.6
  • 66
    • 55449130788 scopus 로고    scopus 로고
    • Orexin affects dorsal root ganglion neurons: a mechanism for regulating the spinal nociceptive processing
    • Yan J.A., Ge L., Huang W., Song B., Chen X.W., Yu Z.P. Orexin affects dorsal root ganglion neurons: a mechanism for regulating the spinal nociceptive processing. Physiol Res/Acad Sci Bohemoslov 2008, 57:797-800.
    • (2008) Physiol Res/Acad Sci Bohemoslov , vol.57 , pp. 797-800
    • Yan, J.A.1    Ge, L.2    Huang, W.3    Song, B.4    Chen, X.W.5    Yu, Z.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.