Direct regulation of osteocytic connexin 43 hemichannels through AKT kinase activated by mechanical stimulation

Journal of Biological Chemistry

Volumn 289, Issue 15, 2014, Pages 10582-10591

  Batra, Nidhi ^a   Riquelme, Manuel A ^a   Burra, Sirisha ^a   Kar, Rekha ^a   Gu, Sumin ^a   Jiang, Jean X ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

BONE REMODELING; CONNEXIN 43; HEMICHANNELS; INTEGRINS; MECHANICAL STIMULATION; MECHANICAL STRESS; REGULATORY MECHANISM;

STRESSES;

ALPHA5 INTEGRIN; CONNEXIN 43; PROTEIN KINASE B; SERINE;

ANIMAL CELL; ARTICLE; BONE TISSUE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GAP JUNCTION; HEMICHANNEL; IN VITRO STUDY; MECHANICAL STIMULATION; MOUSE; NONHUMAN; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RAT; SHEAR STRESS;

AKT; CONNEXIN; INTEGRIN; MECHANOTRANSDUCTION; PHOSPHORYLATION;

ANIMALS; CELL LINE; COLLAGEN; CONNEXIN 43; CONNEXINS; GAP JUNCTIONS; GENE EXPRESSION REGULATION; INTEGRIN ALPHA5; MICE; OSTEOCYTES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECOMBINANT FUSION PROTEINS; SERINE; SHEAR STRENGTH; STRESS, MECHANICAL;

EID: 84898627374     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.550608     Document Type: Article

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