-
1
-
-
4644237315
-
Melanin pigmentation in mammalian skin and its hormonal regulation
-
DOI 10.1152/physrev.00044.2003
-
Slominski A, Tobin DJ, Shibahara S, Wortsman J. (2004) Melanin pigmentation in mammalian skin and its hormonal regulation. Physiol Rev 84: 1155-1228. (Pubitemid 39287950)
-
(2004)
Physiological Reviews
, vol.84
, Issue.4
, pp. 1155-1228
-
-
Slominski, A.1
Tobin, D.J.2
Shibahara, S.3
Wortsman, J.4
-
3
-
-
84874100935
-
Prognostication in eye cancer: The latest tumor, node, metastasis classification and beyond
-
20130 Lond
-
Kivelä T, Kujala E. (20130 Prognostication in eye cancer: the latest tumor, node, metastasis classification and beyond. Eye (Lond) 27: 243-252.
-
Eye
, vol.27
, pp. 243-252
-
-
Kivelä, T.1
Kujala, E.2
-
4
-
-
0034661340
-
Early detection and treatment of skin cancer
-
Jerant AF, Johnson JT, Sheridan CD, Caffrey TJ. (2000) Early detection and treatment of skin cancer. Am Fam Physician 62: 357-368, 375-376, 381-382.
-
(2000)
Am Fam Physician
, vol.62
-
-
Jerant, A.F.1
Johnson, J.T.2
Sheridan, C.D.3
Caffrey, T.J.4
-
6
-
-
71549154751
-
Sirtuins, melatonin and circadian rhythms: Building a bridge between aging and cancer
-
Jung-Hynes B, Reiter RJ, Ahmad N. (2010) Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J Pineal Res 48: 9-19.
-
(2010)
J Pineal Res
, vol.48
, pp. 9-19
-
-
Jung-Hynes, B.1
Reiter, R.J.2
Ahmad, N.3
-
7
-
-
80053197058
-
Circadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night
-
Blask DE, Hill SM, Dauchy RT, Xiang S, Yuan L et al. (2011) Circadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night. J Pineal Res 51: 259-269.
-
(2011)
J Pineal Res
, vol.51
, pp. 259-269
-
-
Blask, D.E.1
Hill, S.M.2
Dauchy, R.T.3
Xiang, S.4
Yuan, L.5
-
8
-
-
84856706859
-
Melatonin prevents human pancreatic carcinoma cell PANC-1-induced human umbilical vein endothelial cell proliferation and migration by inhibiting vascular endothelial growth factor expression
-
Cui P, Yu M, Peng X, Dong L, Yang Z. (2012) Melatonin prevents human pancreatic carcinoma cell PANC-1-induced human umbilical vein endothelial cell proliferation and migration by inhibiting vascular endothelial growth factor expression. J Pineal Res 52: 236-243.
-
(2012)
J Pineal Res
, vol.52
, pp. 236-243
-
-
Cui, P.1
Yu, M.2
Peng, X.3
Dong, L.4
Yang, Z.5
-
9
-
-
84863602663
-
Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells
-
Wang J, Xiao X, Zhang Y, Shi D, Chen W et al. (2012) Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells. J Pineal Res 53: 77-90.
-
(2012)
J Pineal Res
, vol.53
, pp. 77-90
-
-
Wang, J.1
Xiao, X.2
Zhang, Y.3
Shi, D.4
Chen, W.5
-
10
-
-
84863595623
-
Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells
-
Uguz AC, Cig B, Espino J, Bejarano I, Naziroglu M et al. (2012) Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. J Pineal Res 53: 91-98.
-
(2012)
J Pineal Res
, vol.53
, pp. 91-98
-
-
Uguz, A.C.1
Cig, B.2
Espino, J.3
Bejarano, I.4
Naziroglu, M.5
-
11
-
-
84863571564
-
Melatonin enhances thapsigargin-induced apoptosis through reactive oxygen species-mediated upregulation of CCAAT-enhancer-binding protein homologous protein in human renal cancer cells
-
Min KJ, Kim HS, Park EJ, Kwon TK. (2012) Melatonin enhances thapsigargin-induced apoptosis through reactive oxygen species-mediated upregulation of CCAAT-enhancer-binding protein homologous protein in human renal cancer cells. J Pineal Res 53: 99-106.
-
(2012)
J Pineal Res
, vol.53
, pp. 99-106
-
-
Min, K.J.1
Kim, H.S.2
Park, E.J.3
Kwon, T.K.4
-
12
-
-
1642562820
-
Regulation of antioxidant enzymes: A significant role for melatonin
-
DOI 10.1046/j.1600-079X.2003.00092.x
-
Rodriguez C, Mayo JC, Sainz RM, Antolín I, Herrera F et al. (2004) Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 36: 1-9. (Pubitemid 38130283)
-
(2004)
Journal of Pineal Research
, vol.36
, Issue.1
, pp. 1-9
-
-
Rodriguez, C.1
Mayo, J.C.2
Sainz, R.M.3
Antolin, I.4
Herrera, F.5
Martin, V.6
Reiter, R.J.7
-
13
-
-
0002979059
-
Melatonin: A potent, endogenous hydroxyl radical scavenger
-
Tan DX, Chen LD, Poeggeler B, Manchester LC, Reiter RJ. (1993) Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1: 57-60.
-
(1993)
Endocr J
, vol.1
, pp. 57-60
-
-
Tan, D.X.1
Chen, L.D.2
Poeggeler, B.3
Manchester, L.C.4
Reiter, R.J.5
-
15
-
-
79960380554
-
Melatonin as a natural ally against oxidative stress: A physicochemical examination
-
Galano A, Tan DX, Reiter RJ. (2011) Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 51: 1-16.
-
(2011)
J Pineal Res
, vol.51
, pp. 1-16
-
-
Galano, A.1
Tan, D.X.2
Reiter, R.J.3
-
16
-
-
68249129060
-
Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines
-
Hardeland R, Tan DX, Reiter RJ. (2009) Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res 47: 109-126.
-
(2009)
J Pineal Res
, vol.47
, pp. 109-126
-
-
Hardeland, R.1
Tan, D.X.2
Reiter, R.J.3
-
17
-
-
77950663581
-
Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease
-
Paradies G, Petrosillo G, Paradies V, Reiter RJ, Ruggiero FM. (2010) Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease. J Pineal Res 48: 297-310.
-
(2010)
J Pineal Res
, vol.48
, pp. 297-310
-
-
Paradies, G.1
Petrosillo, G.2
Paradies, V.3
Reiter, R.J.4
Ruggiero, F.M.5
-
18
-
-
84856244012
-
Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia
-
Kilic U, Yilmaz B, Ugur M, Yüksel A, Reiter RJ et al. (2012) Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia. J Pineal Res 52: 228-235.
-
(2012)
J Pineal Res
, vol.52
, pp. 228-235
-
-
Kilic, U.1
Yilmaz, B.2
Ugur, M.3
Yüksel, A.4
Reiter, R.J.5
-
19
-
-
67649970221
-
Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: Therapeutic implications for prostate cancer
-
Joo SS, Yoo YM. (2009) Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. J Pineal Res 47: 8-14.
-
(2009)
J Pineal Res
, vol.47
, pp. 8-14
-
-
Joo, S.S.1
Yoo, Y.M.2
-
20
-
-
79251474377
-
Melatonin induces apoptotic cell death via p53 in LNCaP cells
-
Kim CH, Yoo YM. (2010) Melatonin induces apoptotic cell death via p53 in LNCaP cells. Korean J Physiol Pharmacol 14: 365-369.
-
(2010)
Korean J Physiol Pharmacol
, vol.14
, pp. 365-369
-
-
Kim, C.H.1
Yoo, Y.M.2
-
21
-
-
84866247938
-
Melatonin-induced autophagy is associated with degradation of MyoD protein in C2C12 myoblast cells
-
Kim CH, Kim KH, Yoo YM. (2012) Melatonin-induced autophagy is associated with degradation of MyoD protein in C2C12 myoblast cells. J Pineal Res 53: 289-297.
-
(2012)
J Pineal Res
, vol.53
, pp. 289-297
-
-
Kim, C.H.1
Kim, K.H.2
Yoo, Y.M.3
-
22
-
-
0022377885
-
Effect of melatonin on B16 melanoma growth in athymic mice
-
Narita T, Kudo H. (1985) Effect of melatonin on B16 melanoma growth in athymic mice. Cancer Res 45: 4175-4177. (Pubitemid 16224870)
-
(1985)
Cancer Research
, vol.45
, Issue.9
, pp. 4175-4177
-
-
Narita, T.1
Kudo, H.2
-
23
-
-
0035037747
-
Direct antiproliferative effects of melatonin on two metastatic cell sublines of mouse melanoma (B16BL6 and PG19)
-
DOI 10.1097/00008390-200104000-00016
-
Cos S, Garcia-Bolado A, Sánchez-Barceló EJ. (2001) Direct antiproliferative effects of melatonin on two metastatic cell sublines of mouse melanoma (B16BL6 and PG19). Melanoma Res 11: 197-201. (Pubitemid 32385825)
-
(2001)
Melanoma Research
, vol.11
, Issue.2
, pp. 197-201
-
-
Cos, S.1
Garcia-Bolado, A.2
Sanchez-Barcelo, E.J.3
-
24
-
-
0038242024
-
Pharmacological action of high doses of melatonin on B16 murine melanoma cells depends on cell number at time of exposure
-
DOI 10.1097/00008390-200304000-00002
-
Yerneni LK, Jayaraman S. (2003) Pharmacological action of high doses of melatonin on B16 murine melanoma cells depends on cell number at time of exposure. Melanoma Res 13: 113-117. (Pubitemid 36583972)
-
(2003)
Melanoma Research
, vol.13
, Issue.2
, pp. 113-117
-
-
Yerneni, L.K.1
Jayaraman, S.2
-
25
-
-
77954323682
-
Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells
-
Cabrera J, Negrín G, Estévez F, Loro J, Reiter RJ et al. (2010) Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells. J Pineal Res 49: 45-54.
-
(2010)
J Pineal Res
, vol.49
, pp. 45-54
-
-
Cabrera, J.1
Negrín, G.2
Estévez, F.3
Loro, J.4
Reiter, R.J.5
-
27
-
-
1842557598
-
MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells
-
DOI 10.1111/j.1600-079X.2004.00119.x
-
Kadekaro AL, Andrade LN, Floeter-Winter LM, Rollag MD, Virador V et al. (2004) MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells. J Pineal Res 36: 204-211. (Pubitemid 38429287)
-
(2004)
Journal of Pineal Research
, vol.36
, Issue.3
, pp. 204-211
-
-
Kadekaro, A.L.1
Andrade, L.N.S.2
Floeter-Winter, L.M.3
Rollag, M.D.4
Virador, V.5
Vieira, W.6
Castrucci, A.M.D.L.7
-
28
-
-
33749327295
-
Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines
-
Fischer TW, Zmijewski MA, Zbytek B, Sweatman TW, Slominski RM et al. (2006) Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines. Int J Oncol 29: 665-672.
-
(2006)
Int J Oncol
, vol.29
, pp. 665-672
-
-
Fischer, T.W.1
Zmijewski, M.A.2
Zbytek, B.3
Sweatman, T.W.4
Slominski, R.M.5
-
29
-
-
0027714815
-
Melatonin interactions with cultured murine B16 melanoma cells
-
Helton RA, Harrison WA, Kelley K, Kane MA. (1993) Melatonin interactions with cultured murine B16 melanoma cells. Melanoma Res 3: 403-413. (Pubitemid 24051363)
-
(1993)
Melanoma Research
, vol.3
, Issue.6
, pp. 403-413
-
-
Helton, R.A.1
Harrison, W.A.2
Kelley, K.3
Kane, M.A.4
-
30
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
Bjornsti MA, Houghton PJ. (2004) The TOR pathway: a target for cancer therapy. Nat Rev Cancer 4: 335-348. (Pubitemid 38579480)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 335-348
-
-
Bjornsti, M.-A.1
Houghton, P.J.2
-
31
-
-
24044551995
-
PI3K/Akt/mTOR pathway as a target for cancer therapy
-
DOI 10.1097/01.cad.0000173476.67239.3b
-
Morgensztern D, McLeod HL. (2005) PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16: 797-803. (Pubitemid 41215743)
-
(2005)
Anti-Cancer Drugs
, vol.16
, Issue.8
, pp. 797-803
-
-
Morgensztern, D.1
McLeod, H.L.2
-
32
-
-
33646706052
-
Oncogenic PI3K and its role in cancer
-
DOI 10.1097/01.cco.0000198021.99347.b9, PII 0000162220060100000013
-
Samuels Y, Ericson K. (2006) Oncogenic PI3K and its role in cancer. Curr Opin Oncol 18: 77-82. (Pubitemid 43740454)
-
(2006)
Current Opinion in Oncology
, vol.18
, Issue.1
, pp. 77-82
-
-
Samuels, Y.1
Ericson, K.2
-
33
-
-
84868528894
-
The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancer
-
Slomovitz BM, Coleman RL. (2012) The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancer. Clin Cancer Res 18: 5856-5864.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5856-5864
-
-
Slomovitz, B.M.1
Coleman, R.L.2
-
34
-
-
0032929762
-
Signalling through phosphoinositide 3-kinases: The lipids take centre stage
-
DOI 10.1016/S0955-0674(99)80029-5
-
Leevers SJ, Vanhaesebroeck B, Waterfield MD. (1999) Signalling through phosphoinositide 3-kinases: the lipids take centre stage. Curr Opin Cell Biol 11: 219-225. (Pubitemid 29164037)
-
(1999)
Current Opinion in Cell Biology
, vol.11
, Issue.2
, pp. 219-225
-
-
Leevers, S.J.1
Vanhaesebroeck, B.2
Waterfield, M.D.3
-
35
-
-
84873867668
-
Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma
-
Xie X, White EP, Mehnert JM. (2013) Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma. PLoS One 8: e55096.
-
(2013)
PLoS One
, vol.8
-
-
Xie, X.1
White, E.P.2
Mehnert, J.M.3
-
36
-
-
78651388423
-
Vertical inhibition of the mTORC1/mTORC2/PI3K pathway shows synergistic effects against melanoma in vitro and in vivo
-
Werzowa J, Koehrer S, Strommer S, Cejka D, Fuereder T et al. (2011) Vertical inhibition of the mTORC1/mTORC2/PI3K pathway shows synergistic effects against melanoma in vitro and in vivo. J Invest Dermatol 131: 495-503.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 495-503
-
-
Werzowa, J.1
Koehrer, S.2
Strommer, S.3
Cejka, D.4
Fuereder, T.5
-
37
-
-
40649126759
-
mTOR is activated in the majority of malignant melanomas
-
DOI 10.1038/sj.jid.5701074, PII 5701074
-
Karbowniczek M, Spittle CS, Morrison T, Wu H, Henske EP. (2008) mTOR is activated in the majority of malignant melanomas. J Invest Dermatol 128: 980-987. (Pubitemid 351374287)
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.4
, pp. 980-987
-
-
Karbowniczek, M.1
Spittle, C.S.2
Morrison, T.3
Wu, H.4
Henske, E.P.5
-
38
-
-
21344456180
-
The Ras/Raf/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
-
Meier F, Schittek B, Busch S, Garbe C, Smalley K et al. (2005) The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front Biosci 10: 2986-3001. (Pubitemid 40910537)
-
(2005)
Frontiers in Bioscience
, vol.10
, Issue.SUPPL. 3
, pp. 2986-3001
-
-
Meier, F.1
Schittek, B.2
Busch, S.3
Garbe, C.4
Smalley, K.5
Satyamoorthy, K.6
Li, G.7
Herlyn, M.8
-
39
-
-
84862830150
-
Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis
-
Zha L, Fan L, Sun G, Wang H, Ma T et al. (2012) Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. J Pineal Res 52: 322-331.
-
(2012)
J Pineal Res
, vol.52
, pp. 322-331
-
-
Zha, L.1
Fan, L.2
Sun, G.3
Wang, H.4
Ma, T.5
-
40
-
-
84855744813
-
Dual inhibition of (V600E) BRAF and the PI3K/AKT/mTOR pathway cooperates to induce apoptosis in melanoma cells through a MEK-independent mechanism
-
Sánchez-Hernández I, Baquero P, Calleros L, Chiloeches A. (2012) Dual inhibition of (V600E) BRAF and the PI3K/AKT/mTOR pathway cooperates to induce apoptosis in melanoma cells through a MEK-independent mechanism. Cancer Lett 314: 244-255.
-
(2012)
Cancer Lett
, vol.314
, pp. 244-255
-
-
Sánchez-Hernández, I.1
Baquero, P.2
Calleros, L.3
Chiloeches, A.4
-
41
-
-
65549142212
-
Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors
-
Marone R, Erhart D, Mertz AC, Bohnacker T, Schnell C et al. (2009) Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors. Mol Cancer Res 7: 601-613.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 601-613
-
-
Marone, R.1
Erhart, D.2
Mertz, A.C.3
Bohnacker, T.4
Schnell, C.5
-
42
-
-
17144427728
-
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
-
Takeuchi H, Kondo Y, Fujiwara K, Kanzawa T, Aoki H et al. (2005) Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 65: 3336-3346. (Pubitemid 40524618)
-
(2005)
Cancer Research
, vol.65
, Issue.8
, pp. 3336-3346
-
-
Takeuchi, H.1
Kondo, Y.2
Fujiwara, K.3
Kanzawa, T.4
Aoki, H.5
Mills, G.B.6
Kondo, S.7
-
43
-
-
67349103358
-
Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide
-
Sinnberg T, Lasithiotakis K, Niessner H, Schittek B, Flaherty KT et al. (2009) Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide. J Invest Dermatol 129: 1500-1515.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1500-1515
-
-
Sinnberg, T.1
Lasithiotakis, K.2
Niessner, H.3
Schittek, B.4
Flaherty, K.T.5
-
44
-
-
0142029990
-
The role of Bcl-2 family members in the progression of cutaneous melanoma
-
DOI 10.1023/A:1025874502181
-
Bush JA, Li G. (2003) The role of Bcl-2 family members in the progression of cutaneous melanoma. Clin Exp Metastasis 20: 531-539. (Pubitemid 37297181)
-
(2003)
Clinical and Experimental Metastasis
, vol.20
, Issue.6
, pp. 531-539
-
-
Bush, J.A.1
Li, G.2
-
45
-
-
33645235858
-
Bcl-xL and bcl-2 proteins in melanoma progression and UVB-induced apoptosis
-
Zhang H, Rosdahl I. (2006) Bcl-xL and bcl-2 proteins in melanoma progression and UVB-induced apoptosis. Int J Oncol 28: 661-666.
-
(2006)
Int J Oncol
, vol.28
, pp. 661-666
-
-
Zhang, H.1
Rosdahl, I.2
-
46
-
-
47349099502
-
Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells
-
DOI 10.1038/jid.2008.44, PII JID200844
-
Lasithiotakis KG, Sinnberg TW, Schittek B, Flaherty KT, Kulms D et al. (2008) Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells. J Invest Dermatol 128: 2013-2023. (Pubitemid 352001225)
-
(2008)
Journal of Investigative Dermatology
, vol.128
, Issue.8
, pp. 2013-2023
-
-
Lasithiotakis, K.G.1
Sinnberg, T.W.2
Schittek, B.3
Flaherty, K.T.4
Kulms, D.5
MacZey, E.6
Garbe, C.7
Meier, F.E.8
-
47
-
-
0032772367
-
The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB
-
Wang JM, Chao JR, Chen W, Kuo ML, Yen JJ et al. (1999) The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB. Mol Cell Biol 19: 6195-6206. (Pubitemid 29399324)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.9
, pp. 6195-6206
-
-
Wang, J.U.-M.1
Chao, J.-R.2
Chen, W.3
Kuo, M.-L.4
Yen, J.J.-Y.5
Yang-Yen, H.-F.6
-
48
-
-
0037401765
-
Activation of extracellular signal-regulated kinases ERK1 and ERK2 induces Bcl-xL up-regulation via inhibition of caspase activities in erythropoietin signaling
-
DOI 10.1002/jcp.10245
-
Mori M, Uchida M, Watanabe T, Kirito K, Hatake K et al. (2003) Activation of extracellular signal-regulated kinases ERK1 and ERK2 induces Bcl-xL upregulation via inhibition of caspase activities in erythropoietin signaling. J Cell Physiol 195: 290-297. (Pubitemid 36384302)
-
(2003)
Journal of Cellular Physiology
, vol.195
, Issue.2
, pp. 290-297
-
-
Mori, M.1
Uchida, M.2
Watanabe, T.3
Kirito, K.4
Hatake, K.5
Ozawa, K.6
Komatsu, N.7
-
49
-
-
4143066849
-
Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt
-
DOI 10.1038/sj.onc.1207698
-
Asnaghi L, Calastretti A, Bevilacqua A, D'Agnano I, Gatti G et al. (2004) Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. Oncogene 23: 5781-5791. (Pubitemid 39093023)
-
(2004)
Oncogene
, vol.23
, Issue.34
, pp. 5781-5791
-
-
Asnaghi, L.1
Calastretti, A.2
Bevilacqua, A.3
D'Agnano, I.4
Gatti, G.5
Canti, G.6
Delia, D.7
Capaccioli, S.8
Nicolin, A.9
-
50
-
-
18844409151
-
Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax: Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity
-
DOI 10.1038/sj.onc.1208471
-
Tirado OM, Mateo-Lozano S, Notario V. (2005) Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax:Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity. Oncogene 24: 3348-3357. (Pubitemid 40695116)
-
(2005)
Oncogene
, vol.24
, Issue.20
, pp. 3348-3357
-
-
Tirado, O.M.1
Mateo-Lozano, S.2
Notario, V.3
-
51
-
-
33746118057
-
Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
-
DOI 10.1158/0008-5472.CAN-05-3018
-
Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH et al. (2006) Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res 66: 6589-6597. (Pubitemid 44085614)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6589-6597
-
-
Vega, F.1
Medeiros, L.J.2
Leventaki, V.3
Atwell, C.4
Cho-Vega, J.H.5
Tian, L.6
Claret, F.-X.7
Rassidakis, G.Z.8
-
52
-
-
27444436166
-
Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation
-
DOI 10.1074/jbc.M506551200
-
Rahmani M, Davis EM, Bauer C, Dent P, Grant S. (2005) Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves downregulation of Mcl-1 through inhibition of translation. J Biol Chem 280: 35217-35227. (Pubitemid 41532709)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35217-35227
-
-
Rahmani, M.1
Davis, E.M.2
Bauer, C.3
Dent, P.4
Grant, S.5
-
53
-
-
27144502652
-
The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006
-
DOI 10.1038/sj.onc.1208841, PII 1208841
-
Yu C, Bruzek LM, Meng XW, Gores GJ, Carter CA et al. (2005) The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006. Oncogene 24: 6861-6869. (Pubitemid 41509409)
-
(2005)
Oncogene
, vol.24
, Issue.46
, pp. 6861-6869
-
-
Yu, C.1
Bruzek, L.M.2
Xue, W.M.3
Gores, G.J.4
Carter, C.A.5
Kaufmann, S.H.6
Adjei, A.A.7
-
54
-
-
32944479041
-
The raf inhibitor BAY 43-9006 (sorafenib) induces caspase-independent apoptosis in melanoma cells
-
DOI 10.1158/0008-5472.CAN-05-0808
-
Panka DJ, Wang W, Atkins MB, Mier JW. (2006) The Raf inhibitor BAY 43-9006 (Sorafenib) induces caspase-independent apoptosis in melanoma cells. Cancer Res 66: 1611-1619. (Pubitemid 43259945)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1611-1619
-
-
Panka, D.J.1
Wang, W.2
Atkins, M.B.3
Mier, J.W.4
-
55
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
DOI 10.1038/nrm2199, PII NRM2199
-
Ron D, Walter P. (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529. (Pubitemid 46985379)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
56
-
-
13644256191
-
A selective inhibitor of elF2alpha dephosphorylation protects cells from ER stress
-
DOI 10.1126/science.1101902
-
Boyce M, Bryant KF, Jousse C, Long K, Harding HP et al. (2005) A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 307: 935-939. (Pubitemid 40229232)
-
(2005)
Science
, vol.307
, Issue.5711
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
Kaufman, R.J.7
Ma, D.8
Coen, D.M.9
Ron, D.10
Yuan, J.11
-
57
-
-
56349170252
-
Involvement of endoplasmic reticulum stress in Docetaxel-induced JNK-dependent apoptosis of human melanoma
-
Mhaidat NM, Thorne R, Zhang XD, Hersey P. (2008) Involvement of endoplasmic reticulum stress in Docetaxel-induced JNK-dependent apoptosis of human melanoma. Apoptosis 13: 1505-1512.
-
(2008)
Apoptosis
, vol.13
, pp. 1505-1512
-
-
Mhaidat, N.M.1
Thorne, R.2
Zhang, X.D.3
Hersey, P.4
-
58
-
-
84865963073
-
Induction of apoptosis by 11-dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cells
-
Su TR, Tsai FJ, Lin JJ, Huang HH, Chiu CC et al. (2012) Induction of apoptosis by 11-dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cells. Mar Drugs 10: 1883-1898.
-
(2012)
Mar Drugs
, vol.10
, pp. 1883-1898
-
-
Su, T.R.1
Tsai, F.J.2
Lin, J.J.3
Huang, H.H.4
Chiu, C.C.5
|