Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Huang, Yuan ^a,b   Caputo, Christina R ^c   Noordmans, Gerda A ^a   Yazdani, Saleh ^a   Monteiro, Luiz Henrique ^a   Van Den Born, Jaap ^a   Van Goor, Harry ^a   Heeringa, Peter ^a   Korstanje, Ron ^c   Hillebrands, Jan Luuk ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b FUDAN UNIVERSITY   (China)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; PODOPLANIN; WNT PROTEIN; CD30 ANTIGEN; CTNNBIP1 PROTEIN, HUMAN; SIGNAL PEPTIDE; WISP-2 PROTEIN, MOUSE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD45+ B LYMPHOCYTE; CD45+ T LYMPHOCYTE; CHROMOSOME 1; CHROMOSOME 13; CHROMOSOME 14; CHROMOSOME 2; CHROMOSOME 4; CHROMOSOME 7; CHROMOSOME 8; CONTROLLED STUDY; CTNNBIP1 GENE; FEMALE; GENE; GENE IDENTIFICATION; GENE MAPPING; GENETIC ASSOCIATION; HAPLOTYPE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; KIDNEY DISEASE; LYMPH VESSEL; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TERTIARY LYMPHOID ORGAN FORMATION; TNFRSF8 GENE; VASCULAR ENDOTHELIUM; VENULE; WISP2 GENE; ANIMAL; GENETICS; IMMUNOLOGY; KIDNEY; LIVER; LYMPHOID TISSUE; METABOLISM; PATHOLOGY; PHENOTYPE; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

AGING; ANIMALS; ANTIGENS, CD30; FEMALE; GENETIC ASSOCIATION STUDIES; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; LIVER; LYMPHATIC VESSELS; LYMPHOID TISSUE; MALE; MICE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS;

EID: 84898605246     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091850     Document Type: Article

References (41)

1. Hoang K, Tan JC, Derby G, Blouch KL, Masek M, et al. (2003) Determinants of glomerul (Pubitemid 37153808)
2. Choudhury D, Levi M. (2011) Kidney aging-inevitable or preventable? Nat Rev Nephrol 7:706-717.
3. Lindeman RD, Tobin J, Shock NW. (1985) Longitudinal studies on the rate of decline in renal function with age. J Am Geriatr Soc 33:278-285. (Pubitemid 15087125)
4. Melk A, Mansfield ES, Hsieh SC, Hernandez-Boussard T, Grimm P, et al. (2005) Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling. Kidney Int 68:2667-2679. (Pubitemid 43251012)
5. Venkatachalam MA, Griffin KA, Lan R, Geng H, Saikumar P, et al. (2010) Acute kidney injury: A springboard for progression in chronic kidney disease. Am J Physiol Renal Physiol 298:F1078-94.
6. Rodwell GE, Sonu R, Zahn JM, Lund J, Wilhelmy J, et al. (2004) A transcriptional profile of aging in the human kidney. PLoS Biol 2:e427.
7. Brink TC, Regenbrecht C, Demetrius L, Lehrach H, Adjaye J. (2009) Activation of the immune response is a key feature of aging in mice. Biogerontology 10:721-734.
8. Tullius SG, Milford E. (2011) Kidney allocation and the aging immune response. N Engl J Med 364:1369-1370.
9. Drayton DL, Liao S, Mounzer RH, Ruddle NH. (2006) Lymphoid organ development: From ontogeny to neogenesis. Nat Immunol 7:344-353.
10. Kelly FM, Reddy RN, Roberts BR, Gangappa S, Williams IR, et al. (2009) TGF-beta upregulation drives tertiary lymphoid organ formation and kidney dysfunction in calcineurin A-alpha heterozygous mice. Am J Physiol Renal Physiol 296:F512-20.
11. Tsaih SW, Korstanje R. (2009) Haplotype association mapping in mice. Methods Mol Biol 573:213-222.
12. Sinke AP, Caputo C, Tsaih SW, Yuan R, Ren D, et al. (2011) Genetic analysis of mouse strains with variable serum sodium concentrations identifies the nalcn sodium channel as a novel player in osmoregulation. Physiol Genomics 43:265-270.
13. Tsaih SW, Pezzolesi MG, Yuan R, Warram JH, Krolewski AS, et al. (2010) Genetic analysis of albuminuria in aging mice and concordance with loci for human diabetic nephropathy found in a genome-wide association scan. Kidney Int 77:201-210.
14. Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, et al. (2008) Efficient control of population structure in model organism association mapping. Genetics 178:1709-1723.
15. Aloisi F, Pujol-Borrell R. (2006) Lymphoid neogenesis in chronic inflammatory diseases. Nat Rev Immunol 6:205-217. (Pubitemid 43290990)
16. Mounzer RH, Svendsen OS, Baluk P, Bergman CM, Padera TP, et al. (2010) Lymphotoxin-alpha contributes to lymphangiogenesis. Blood 116:2173-2182.
17. Pabst R. (2007) Plasticity and heterogeneity of lymphoid organs. what are the criteria to call a lymphoid organ primary, secondary or tertiary? Immunol Lett 112:1-8. (Pubitemid 47331688)
18. Matsui K, Nagy-Bojarsky K, Laakkonen P, Krieger S, Mechtler K, et al. (2003) Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: Aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels. J Am Soc Nephrol 14:1981-1989. (Pubitemid 36909905)
19. Lee AS, Lee JE, Jung YJ, Kim DH, Kang KP, et al. (2013) Vascular endothelial growth factor-C and-D are involved in lymphangiogenesis in mouse unilateral ureteral obstruction. Kidney Int 83:50-62.
20. Hjelmstrom P. (2001) Lymphoid neogenesis: De novo formation of lymphoid tissue in chronic inflammation through expression of homing chemokines. J Leukoc Biol 69:331-339. (Pubitemid 32221435)
21. Thaunat O, Field AC, Dai J, Louedec L, Patey N, et al. (2005) Lymphoid neogenesis in chronic rejection: Evidence for a local humoral alloimmune response. Proc Natl Acad Sci U S A 102:14723-14728. (Pubitemid 41457123)
22. Watanabe Y, Itoh Y, Yoshida F, Koh N, Tamai H, et al. (1991) Unique glomerular lesion with spontaneous lipid deposition in glomerular capillary lumina in the NON strain of mice. Nephron 58:210-218.
23. Van Goor H, Leuvenink HG. (2009) The goddess of the waters. Kidney Int 75:767-769.
24. Thaunat O, Kerjaschki D, Nicoletti A. (2006) Is defective lymphatic drainage a trigger for lymphoid neogenesis? Trends Immunol 27:441-445. (Pubitemid 44354310)
25. Nasr IW, Reel M, Oberbarnscheidt MH, Mounzer RH, Baddoura FK, et al. (2007) Tertiary lymphoid tissues generate effector and memory T cells that lead to allograft rejection. Am J Transplant 7:1071-1079. (Pubitemid 46643108)
26. Thaunat O, Patey N, Caligiuri G, Gautreau C, Mamani-Matsuda M, et al. (2010) Chronic rejection triggers the development of an aggressive intragraft immune response through recapitulation of lymphoid organogenesis. J Immunol 185:717-728.
27. Carragher DM, Rangel-Moreno J, Randall TD. (2008) Ectopic lymphoid tissues and local immunity. Semin Immunol 20:26-42.
28. Pablos JL, Santiago B, Tsay D, Singer MS, Palao G, et al. (2005) A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells. BMC Immunol 6:6.
29. Salomonsson S, Larsson P, Tengner P, Mellquist E, Hjelmstrom P, et al. (2002) Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease sjogren's syndrome. Scand J Immunol 55:336-342. (Pubitemid 34429788)
30. Segerer S, Schlondorff D. (2008) B cells and tertiary lymphoid organs in renal inflammation. Kidney Int 73:533-537. (Pubitemid 351264112)
31. Schwab U, Stein H, Gerdes J, Lemke H, Kirchner H, et al. (1982) Production of a monoclonal antibody specific for hodgkin and sternberg-reed cells of hodgkin's disease and a subset of normal lymphoid cells. Nature 299:65-67. (Pubitemid 12049770)
32. Holbourn KP, Acharya KR, Perbal B. (2008) The CCN family of proteins: Structure-function relationships. Trends Biochem Sci 33:461-473.
33. Pennica D, Swanson TA, Welsh JW, Roy MA, Lawrence DA, et al. (1998) WISP genes are members of the connective tissue growth factor family that are upregulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci U S A 95:14717-14722. (Pubitemid 29003696)
34. Liu J, Ding X, Tang J, Cao Y, Hu P, et al. (2011) Enhancement of canonical Wnt/beta-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS One 6:e27496.
35. Zhang JL, Huang Y, Qiu LY, Nickel J, Sebald W. (2007) Von willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms. J Biol Chem 282:20002-20014. (Pubitemid 47100074)
36. Tago K, Nakamura T, Nishita M, Hyodo J, Nagai S, et al. (2000) Inhibition of wnt signaling by ICAT, a novel beta-catenin-interacting protein. Genes Dev 14:1741-1749. (Pubitemid 30602993)
37. Smith CA, Gruss HJ, Davis T, Anderson D, Farrah T, et al. (1993) CD30 antigen, a marker for hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell 73:1349-1360. (Pubitemid 23201148)
38. Horie R, Watanabe T. (1998) CD30: Expression and function in health and disease. Semin Immunol 10:457-470. (Pubitemid 28564375)
39. Gaspal F, Withers D, Saini M, Bekiaris V, McConnell FM, et al. (2011) Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice. J Exp Med 208:1579-1584.
40. Bowen MA, Lee RK, Miragliotta G, Nam SY, Podack ER. (1996) Structure and expression of murine CD30 and its role in cytokine production. J Immunol 156:442-449. (Pubitemid 26028901)
41. Martin JE, Sheaff MT. (2007) Renal ageing. J Pathol 211:198-205. (Pubitemid 46195518)