Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Cheriyan, Vino T ^b,d   Wang, Ying ^a,b   Muthu, Magesh ^b,d   Jamal, Shazia ^b,d,h   Chen, Di ^a,b   Yang, Huanjie ^f   Polin, Lisa A ^a,b   Tarca, Adi L ^c   Pass, Harvey I ^e   Dou, Q Ping ^a,b   Sharma, Sunita ^a,b   Wali, Anil ^a,d,g   Rishi, Arun K ^a,b,d  

^a KARMANOS CANCER INSTITUTE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Wayne State University   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e NEW YORK UNIVERSITY   (United States)

^f HARBIN INSTITUTE OF TECHNOLOGY   (China)

^g NATIONAL CANCER INSTITUTE   (United States)

^h B S ABDUR RAHMAN CRESCENT INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CASPASE 3; COPPER; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DISULFIRAM; I KAPPA B; I KAPPA B ALPHA; I KAPPA B BETA; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PODOPLANIN; PROTEIN ABIN 1; PROTEIN ABIN 2; PROTEIN CARP 1; PROTEIN CCAR1; PROTEIN IGFBP7; SERINE; SOMATOMEDIN BINDING PROTEIN; STROMELYSIN; STROMELYSIN 2; SULFATASE; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG; VIMENTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL MOTILITY; CELL SURVIVAL; CYTOPLASM; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; METASTASIS; METASTASIS INHIBITION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLEURA MESOTHELIOMA; PROGNOSIS; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LUNG NEOPLASMS; MESOTHELIOMA; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; DISULFIRAM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MESOTHELIOMA; MICE; NEOPLASM PROTEINS; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 84898603170     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093711     Document Type: Article

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