Withaferin a inhibits the proteasome activity in mesothelioma in vitro and in vivo

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Yang, Huanjie ^a,d   Wang, Ying ^a   Cheryan, Vino T ^a   Wu, Wenjuan ^a   Cui, Cindy Qiuzhi ^a   Polin, Lisa A ^a   Pass, Harvey I ^a,c   Dou, Q Ping ^a,b   Rishi, Arun K ^a   Wali, Anil ^a,e  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY   (United States)

^d HARBIN INSTITUTE OF TECHNOLOGY   (China)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CELL CYCLE AND APOPTOSIS REGULATORY PROTEIN 1; I KAPPA B ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEASOME; PROTEIN BAX; PROTEIN C JUN; PROTEIN P21; REGULATOR PROTEIN; UNCLASSIFIED DRUG; WITHAFERIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL GROWTH; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; FEMALE; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; NONHUMAN; ONCOGENE C MYC; PLEURA MESOTHELIOMA; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING;

ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MESOTHELIOMA; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; WITHANOLIDES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865069079     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041214     Document Type: Article

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