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Volumn 9, Issue 3, 2014, Pages 242-249

Modulation of HIV-1 immunity by adjuvants

Author keywords

Adjuvants; antibodies; antigens peptides epitopes; B cells; HIV 1; vaccines

Indexed keywords

ANTIGEN; BACTERIAL VECTOR; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOLOGICAL ADJUVANT; NEUTRALIZING ANTIBODY; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

EID: 84898546111     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0000000000000052     Document Type: Review
Times cited : (7)

References (95)
  • 1
    • 84889770121 scopus 로고    scopus 로고
    • Key roles of adjuvants in modern vaccines
    • Reed SG, Orr MT, Fox CB. Key roles of adjuvants in modern vaccines. Nat Med 2013; 19:1597-1608.
    • (2013) Nat Med , vol.19 , pp. 1597-1608
    • Reed, S.G.1    Orr, M.T.2    Fox, C.B.3
  • 2
    • 9644295705 scopus 로고    scopus 로고
    • The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses
    • Barouch DH, Letvin NL, Seder RA. The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses. Immunol Rev 2004; 202:266-274.
    • (2004) Immunol Rev , vol.202 , pp. 266-274
    • Barouch, D.H.1    Letvin, N.L.2    Seder, R.A.3
  • 3
    • 77958498224 scopus 로고    scopus 로고
    • Vaccine adjuvants: Putting innate immunity to work
    • Coffman RL, Sher A, Seder RA. Vaccine adjuvants: putting innate immunity to work. Immunity 2010; 33:492-503.
    • (2010) Immunity , vol.33 , pp. 492-503
    • Coffman, R.L.1    Sher, A.2    Seder, R.A.3
  • 7
    • 38149072327 scopus 로고    scopus 로고
    • Cytokines as adjuvants for improving anti-HIV responses
    • Morrow MP, Weiner DB. Cytokines as adjuvants for improving anti-HIV responses. AIDS 2008; 22: 333-338.
    • (2008) AIDS , vol.22 , pp. 333-338
    • Morrow, M.P.1    Weiner, D.B.2
  • 8
    • 2942541727 scopus 로고    scopus 로고
    • Enhancement of human immunodeficiency virus type 1-DNA vaccine potency through incorporation of T-helper 1 molecular adjuvants
    • Calarota SA, Weiner DB. Enhancement of human immunodeficiency virus type 1-DNA vaccine potency through incorporation of T-helper 1 molecular adjuvants. Immunol Rev 2004; 199:84-99.
    • (2004) Immunol Rev , vol.199 , pp. 84-99
    • Calarota, S.A.1    Weiner, D.B.2
  • 9
    • 33750742403 scopus 로고    scopus 로고
    • A reflection on HIV/AIDS research after 25 years
    • Gallo RC. A reflection on HIV/AIDS research after 25 years. Retrovirology 2006; 3:72.
    • (2006) Retrovirology , vol.3 , pp. 72
    • Gallo, R.C.1
  • 10
    • 0023912632 scopus 로고
    • A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS
    • Zagury D, Bernard J, Cheynier R, et al. A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS. Nature 1988; 332:728-731.
    • (1988) Nature , vol.332 , pp. 728-731
    • Zagury, D.1    Bernard, J.2    Cheynier, R.3
  • 11
    • 0023105272 scopus 로고
    • Immunization against AIDS in humans
    • Zagury D, Lé onard R, Fouchard M, et al. Immunization against AIDS in humans. Nature 1987; 326:249-250.
    • (1987) Nature , vol.326 , pp. 249-250
    • Zagury, D.1    Léonard, R.2    Fouchard, M.3
  • 12
    • 0027406672 scopus 로고
    • Immune response of chimpanzees after immunization with the inactivated whole immunodeficiency virus (HIV-1), three different adjuvants and challenge
    • Niedrig M, Gregersen JP, Fultz PN, et al. Immune response of chimpanzees after immunization with the inactivated whole immunodeficiency virus (HIV-1), three different adjuvants and challenge. Vaccine 1993; 11:67-74.
    • (1993) Vaccine , vol.11 , pp. 67-74
    • Niedrig, M.1    Gregersen, J.P.2    Fultz, P.N.3
  • 13
    • 0033555453 scopus 로고    scopus 로고
    • Fusion-competent vaccines: Broad neutralization of primary isolates of HIV
    • LaCasse RA, Follis KE, Trahey M, et al. Fusion-competent vaccines: broad neutralization of primary isolates of HIV. Science 1999; 283:357-362.
    • (1999) Science , vol.283 , pp. 357-362
    • Lacasse, R.A.1    Follis, K.E.2    Trahey, M.3
  • 14
    • 0037052488 scopus 로고    scopus 로고
    • Retraction
    • Nunberg JH. Retraction. Science 2002; 296:1025.
    • (2002) Science , vol.296 , pp. 1025
    • Nunberg, J.H.1
  • 15
    • 0024454657 scopus 로고
    • Immune response to immunostimulatory complexes (ISCOMs) prepared from human immunodeficiency virus type 1 (HIV-1) or the HIV-1 external envelope glycoprotein (gp120)
    • Pyle SW, Morein B, Bess JW, et al. Immune response to immunostimulatory complexes (ISCOMs) prepared from human immunodeficiency virus type 1 (HIV-1) or the HIV-1 external envelope glycoprotein (gp120). Vaccine 1989; 7:465-473.
    • (1989) Vaccine , vol.7 , pp. 465-473
    • Pyle, S.W.1    Morein, B.2    Bess, J.W.3
  • 16
    • 0027430975 scopus 로고
    • Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network
    • Belshe RB, Clements ML, Dolin R, et al. Safety and immunogenicity of a fully glycosylated recombinant gp160 human immunodeficiency virus type 1 vaccine in subjects at low risk of infection. National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group Network. J Infect Dis 1993; 168:1387-1395.
    • (1993) J Infect Dis , vol.168 , pp. 1387-1395
    • Belshe, R.B.1    Clements, M.L.2    Dolin, R.3
  • 17
    • 33845433434 scopus 로고    scopus 로고
    • Bangkok Vaccine Evaluation Group: Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    • Pitisuttithum P, Gilbert P, Gurwith M, et al. Bangkok Vaccine Evaluation Group: randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis 2006; 194:1661-1671.
    • (2006) J Infect Dis , vol.194 , pp. 1661-1671
    • Pitisuttithum, P.1    Gilbert, P.2    Gurwith, M.3
  • 18
    • 13944254982 scopus 로고    scopus 로고
    • Rgp120 HIV Vaccine Study Group: Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn NM, Forthal DN, Harro CD, et al. rgp120 HIV Vaccine Study Group: Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis 2005; 191:654-665.
    • (2005) J Infect Dis , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3
  • 19
    • 0025744987 scopus 로고
    • Immunization of chimpanzees with the HIV-1 glycoprotein gp160 induces long-lasting T-cell memory
    • Mannhalter JW, Pum M, Wolf HM, et al. Immunization of chimpanzees with the HIV-1 glycoprotein gp160 induces long-lasting T-cell memory. AIDS Res Hum Retroviruses 1991; 7:485-493.
    • (1991) AIDS Res Hum Retroviruses , vol.7 , pp. 485-493
    • Mannhalter, J.W.1    Pum, M.2    Wolf, H.M.3
  • 20
    • 0027197542 scopus 로고
    • Effects of adjuvants and multiple antigen peptides on humoral and cellular immune responses to gp160 of HIV-1
    • Levi M, Rudén U, Birx D, et al. Effects of adjuvants and multiple antigen peptides on humoral and cellular immune responses to gp160 of HIV-1. J Acquir Immune Defic Syndr 1993; 6:855-864.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 855-864
    • Levi, M.1    Rudén, U.2    Birx, D.3
  • 21
    • 0026742201 scopus 로고
    • High-titer HIV-1 neutralizing antibody response of rhesus macaques to gp160 and env peptides
    • Ronco J, Dedieu JF, Marie FN, et al. High-titer HIV-1 neutralizing antibody response of rhesus macaques to gp160 and env peptides. AIDS Res Hum Retroviruses 1992; 8:1117-1123.
    • (1992) AIDS Res Hum Retroviruses , vol.8 , pp. 1117-1123
    • Ronco, J.1    Dedieu, J.F.2    Marie, F.N.3
  • 22
    • 0026534011 scopus 로고
    • Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine
    • Wu JY, Gardner BH, Murphy CI, et al. Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine. J Immunol 1992; 148:1519-1525.
    • (1992) J Immunol , vol.148 , pp. 1519-1525
    • Wu, J.Y.1    Gardner, B.H.2    Murphy, C.I.3
  • 23
    • 0028202997 scopus 로고
    • Adjuvant effect of liposomes and adamantylamide dipeptide on antigenicity of entrapped synthetic peptide derived from HIV-1 transmembrane region glycoprotein gp41
    • Turánek J, Toman M, Novák J, et al. Adjuvant effect of liposomes and adamantylamide dipeptide on antigenicity of entrapped synthetic peptide derived from HIV-1 transmembrane region glycoprotein gp41. Immunol Lett 1994; 39: 157-161.
    • (1994) Immunol Lett , vol.39 , pp. 157-161
    • Turánek J, T.1
  • 24
    • 0028837225 scopus 로고
    • Comparison of 24 different adjuvants for inactivated HIV-2 split whole virus as antigen in mice. Induction of titres of binding antibodies and toxicity of the formulations
    • Stieneker F, Kersten G, van Bloois L, et al. Comparison of 24 different adjuvants for inactivated HIV-2 split whole virus as antigen in mice. Induction of titres of binding antibodies and toxicity of the formulations. Vaccine 1995; 13:45-53.
    • (1995) Vaccine , vol.13 , pp. 45-53
    • Stieneker, F.1    Kersten, G.2    Van Bloois, L.3
  • 25
    • 0029975955 scopus 로고    scopus 로고
    • Candidate HIV type 1 multi-determinant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization
    • Ahlers JD, Dunlop N, Pendleton CD, et al. Candidate HIV type 1 multi-determinant cluster peptide-P18MN vaccine constructs elicit type 1 helper T cells, cytotoxic T cells, and neutralizing antibody, all using the same adjuvant immunization. AIDS Res Hum Retroviruses 1996; 12:259-272.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 259-272
    • Ahlers, J.D.1    Dunlop, N.2    Pendleton, C.D.3
  • 26
    • 12644300612 scopus 로고    scopus 로고
    • Development of a single-shot subunit vaccine for HIV-1.3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120
    • Cleland JL, Barron L, Daugherty A, et al. Development of a single-shot subunit vaccine for HIV-1.3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120 J Pharm Sci 1996; 85:1350-1357.
    • (1996) J Pharm Sci , vol.85 , pp. 1350-1357
    • Cleland, J.L.1    Barron, L.2    Daugherty, A.3
  • 27
    • 0029658398 scopus 로고    scopus 로고
    • Immunogenicity of HIV-1LAI gp160 and env peptides in squirrel monkey Saimiri sciureus using alumine and experimental adjuvants
    • Perraut R, Chouteau P, Moog C, et al. Immunogenicity of HIV-1LAI gp160 and env peptides in squirrel monkey Saimiri sciureus using alumine and experimental adjuvants. Clin Exp Immunol 1996; 106:434-441.
    • (1996) Clin Exp Immunol , vol.106 , pp. 434-441
    • Perraut, R.1    Chouteau, P.2    Moog, C.3
  • 28
    • 0030876747 scopus 로고    scopus 로고
    • Comparison of nucleic acid and protein immunization for induction of antibodies specific for HIV-1 gp120
    • Peet NM, McKeating JA, Ramos B, et al. Comparison of nucleic acid and protein immunization for induction of antibodies specific for HIV-1 gp120. Clin Exp Immunol 1997; 109:226-232.
    • (1997) Clin Exp Immunol , vol.109 , pp. 226-232
    • Peet, N.M.1    McKeating, J.A.2    Ramos, B.3
  • 29
    • 0032503932 scopus 로고    scopus 로고
    • Adjuvant is required when using Env lipopeptide construct to induce HIV type 1-specific neutralizing antibody responses in mice in vivo
    • Sauzet JP, Moog C, Krivine A, et al. Adjuvant is required when using Env lipopeptide construct to induce HIV type 1-specific neutralizing antibody responses in mice in vivo. AIDS Res Hum Retroviruses 1998; 14:901-909.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 901-909
    • Sauzet, J.P.1    Moog, C.2    Krivine, A.3
  • 30
    • 0032978729 scopus 로고    scopus 로고
    • Comparison of immunity generated by nucleic acid-, MF59-, and ISCOM-formulated human immunodeficiency virus type 1 vaccines in Rhesus macaques: Evidence for viral clearance
    • Verschoor EJ, Mooij P, Oostermeijer H, et al. Comparison of immunity generated by nucleic acid-, MF59-, and ISCOM-formulated human immunodeficiency virus type 1 vaccines in Rhesus macaques: evidence for viral clearance. J Virol 1999; 73:3292-3300.
    • (1999) J Virol , vol.73 , pp. 3292-3300
    • Verschoor, E.J.1    Mooij, P.2    Oostermeijer, H.3
  • 31
    • 0030967937 scopus 로고    scopus 로고
    • Safety profile of phase i and II preventive HIV type 1 envelope vaccination: Experience of the NIAID AIDS Vaccine Evaluation Group
    • Keefer MC, Wolff M, Gorse GJ, et al. Safety profile of phase I and II preventive HIV type 1 envelope vaccination: experience of the NIAID AIDS Vaccine Evaluation Group. AIDS Res Hum Retroviruses 1997; 13:1163-1177.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 1163-1177
    • Keefer, M.C.1    Wolff, M.2    Gorse, G.J.3
  • 32
    • 1342332108 scopus 로고    scopus 로고
    • Public health. A sound rationale needed for phase III HIV-1 vaccine trials
    • Burton DR, Desrosiers RC, Doms RW, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science 2004; 303:316-1316.
    • (2004) Science , vol.303 , pp. 316-1316
    • Burton, D.R.1    Desrosiers, R.C.2    Doms, R.W.3
  • 33
    • 3242806035 scopus 로고    scopus 로고
    • Support for the RV144 HIV Vaccine Trial: New series
    • Belshe R, Franchini G, Girard MP, et al. Support for the RV144 HIV Vaccine Trial: new series. Science 2004; 305:177-180.
    • (2004) Science , vol.305 , pp. 177-180
    • Belshe, R.1    Franchini, G.2    Girard, M.P.3
  • 34
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009; 361:2209-2220.
    • (2009) N Engl J Med , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1    Pitisuttithum, P.2    Nitayaphan, S.3
  • 35
    • 84862764447 scopus 로고    scopus 로고
    • Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: A posthoc analysis of the Thai phase 3 efficacy trial RV 144
    • Robb ML, Rerks-Ngarm S, Nitayaphan S, et al. Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a posthoc analysis of the Thai phase 3 efficacy trial RV 144. Lancet Infect Dis 2012; 12:531-537.
    • (2012) Lancet Infect Dis , vol.12 , pp. 531-537
    • Robb, M.L.1    Rerks-Ngarm, S.2    Nitayaphan, S.3
  • 36
    • 15144348897 scopus 로고    scopus 로고
    • Intranasal administration of human immunodeficiency virus type-1 (HIV-1) DNA vaccine with interleukin-2 expression plasmid enhances cell-mediated immunity against HIV-1
    • Xin KQ, Hamajima K, Sasaki S, et al. Intranasal administration of human immunodeficiency virus type-1 (HIV-1) DNA vaccine with interleukin-2 expression plasmid enhances cell-mediated immunity against HIV-1. Immunology 1998; 94:438-444.
    • (1998) Immunology , vol.94 , pp. 438-444
    • Xin, K.Q.1    Hamajima, K.2    Sasaki, S.3
  • 37
    • 0033605274 scopus 로고    scopus 로고
    • IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine
    • Xin KQ, Hamajima K, Sasaki S, et al. IL-15 expression plasmid enhances cell-mediated immunity induced by an HIV-1 DNA vaccine. Vaccine 1999; 17:858-866.
    • (1999) Vaccine , vol.17 , pp. 858-866
    • Xin, K.Q.1    Hamajima, K.2    Sasaki, S.3
  • 38
    • 0033051038 scopus 로고    scopus 로고
    • Immunization of RANTES expression plasmid with a DNA vaccine enhances HIV-1-specific immunity
    • Xin KQ, Lu Y, Hamajima K, et al. Immunization of RANTES expression plasmid with a DNA vaccine enhances HIV-1-specific immunity. Clin Immunol 1999; 92:90-96.
    • (1999) Clin Immunol , vol.92 , pp. 90-96
    • Xin, K.Q.1    Lu, Y.2    Hamajima, K.3
  • 39
    • 32444446901 scopus 로고    scopus 로고
    • Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines
    • Stone GW, Barzee S, Snarsky V, et al. Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines. J Virol 2006; 80:1762-1772.
    • (2006) J Virol , vol.80 , pp. 1762-1772
    • Stone, G.W.1    Barzee, S.2    Snarsky, V.3
  • 40
    • 33747040210 scopus 로고    scopus 로고
    • Studies on GM-CSF DNA as an adjuvant for neutralizing Ab elicited by a DNA/MVA immunodeficiency virus vaccine
    • Robinson HL, Montefiori DC, Villinger F, et al. Studies on GM-CSF DNA as an adjuvant for neutralizing Ab elicited by a DNA/MVA immunodeficiency virus vaccine. Virology 2006; 352:285-294.
    • (2006) Virology , vol.352 , pp. 285-294
    • Robinson, H.L.1    Montefiori, D.C.2    Villinger, F.3
  • 41
    • 33845201196 scopus 로고    scopus 로고
    • Novel codon-optimized GM-CSF gene as an adjuvant to enhance the immunity of a DNA vaccine against HIV-1 Gag
    • Qiu J-T, Chang T-C, Lin C-T, et al. Novel codon-optimized GM-CSF gene as an adjuvant to enhance the immunity of a DNA vaccine against HIV-1 Gag. Vaccine 2007; 25:253-263.
    • (2007) Vaccine , vol.25 , pp. 253-263
    • Qiu, J.-T.1    Chang, T.-C.2    Lin, C.-T.3
  • 42
    • 33645050385 scopus 로고    scopus 로고
    • Enhancement of immune responses to an HIV gp120 DNA vaccine by fusion to TNF alpha cDNA
    • Nimal S, Heath AW, Thomas MS. Enhancement of immune responses to an HIV gp120 DNA vaccine by fusion to TNF alpha cDNA. Vaccine 2006; 24:3298-3308.
    • (2006) Vaccine , vol.24 , pp. 3298-3308
    • Nimal, S.1    Heath, A.W.2    Thomas, M.S.3
  • 43
    • 33646485514 scopus 로고    scopus 로고
    • Augmenting the immunogenicity of DNA vaccines: Role of plasmid-encoded Flt-3 ligand, as a molecular adjuvant in genetic vaccination
    • Nayak BP, Sailaja G, Jabbar AM. Augmenting the immunogenicity of DNA vaccines: role of plasmid-encoded Flt-3 ligand, as a molecular adjuvant in genetic vaccination. Virology 2006; 348:277-288.
    • (2006) Virology , vol.348 , pp. 277-288
    • Nayak, B.P.1    Sailaja, G.2    Jabbar, A.M.3
  • 44
    • 0032946802 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha (MIP-1alpha) expression plasmid enhances DNA vaccine-induced immune response against HIV-1
    • Lu Y, Xin KQ, Hamajima K, et al. Macrophage inflammatory protein-1alpha (MIP-1alpha) expression plasmid enhances DNA vaccine-induced immune response against HIV-1. Clin Exp Immunol 1999; 115:335-341.
    • (1999) Clin Exp Immunol , vol.115 , pp. 335-341
    • Lu, Y.1    Xin, K.Q.2    Hamajima, K.3
  • 45
    • 84855417996 scopus 로고    scopus 로고
    • Soluble multitrimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine
    • Kanagavelu SK, Snarsky V, Termini JM, et al. Soluble multitrimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine. Vaccine 2012; 30:691-702.
    • (2012) Vaccine , vol.30 , pp. 691-702
    • Kanagavelu, S.K.1    Snarsky, V.2    Termini, J.M.3
  • 46
    • 77954576021 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 acts as a powerful adjuvant in the DNA based vaccination
    • Castaldello A, Sgarbanti M, Marsili G, et al. Interferon regulatory factor-1 acts as a powerful adjuvant in the DNA based vaccination. J Cell Physiol 2010; 224:702-709.
    • (2010) J Cell Physiol , vol.224 , pp. 702-709
    • Castaldello, A.1    Sgarbanti, M.2    Marsili, G.3
  • 47
    • 0038521720 scopus 로고    scopus 로고
    • Enhancement of immune responses to an HIV env DNA vaccine by a C-terminal segment of listeriolysin O
    • Bu Z, Ye L, Skeen MJ, et al. Enhancement of immune responses to an HIV env DNA vaccine by a C-terminal segment of listeriolysin O. AIDS Res Hum Retroviruses 2003; 19:409-420.
    • (2003) AIDS Res Hum Retroviruses , vol.19 , pp. 409-420
    • Bu, Z.1    Ye, L.2    Skeen, M.J.3
  • 48
    • 50849133565 scopus 로고    scopus 로고
    • IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine
    • Calarota SA, Dai A, Trocio JN, et al. IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine. Vaccine 2008; 26:5188-5195.
    • (2008) Vaccine , vol.26 , pp. 5188-5195
    • Calarota, S.A.1    Dai, A.2    Trocio, J.N.3
  • 49
    • 0037080035 scopus 로고    scopus 로고
    • Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF
    • Barouch DH, Santra S, Tenner-Racz K, et al. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. J Immunol 2002; 168:562-568.
    • (2002) J Immunol , vol.168 , pp. 562-568
    • Barouch, D.H.1    Santra, S.2    Tenner-Racz, K.3
  • 50
    • 49549106212 scopus 로고    scopus 로고
    • Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines
    • Xu R, Megati S, Roopchand V, et al. Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines. Vaccine 2008; 26:4819-4829.
    • (2008) Vaccine , vol.26 , pp. 4819-4829
    • Xu, R.1    Megati, S.2    Roopchand, V.3
  • 51
    • 84871665907 scopus 로고    scopus 로고
    • Enhancement of HIV-1 DNA vaccine immunogenicity by BCG-PSN, a novel adjuvant
    • Sun J, Hou J, Li D, et al. Enhancement of HIV-1 DNA vaccine immunogenicity by BCG-PSN, a novel adjuvant. Vaccine 2013; 31:472-479.
    • (2013) Vaccine , vol.31 , pp. 472-479
    • Sun, J.1    Hou, J.2    Li, D.3
  • 52
    • 17844374356 scopus 로고    scopus 로고
    • Augmentation of HIV-1 subtype C vaccine constructs induced immune response in mice by CpG motif 1826-ODN
    • Aggarwal P, Pandey RM, Seth P. Augmentation of HIV-1 subtype C vaccine constructs induced immune response in mice by CpG motif 1826-ODN. Viral Immunol 2005; 18:213-223.
    • (2005) Viral Immunol , vol.18 , pp. 213-223
    • Aggarwal, P.1    Pandey, R.M.2    Seth, P.3
  • 53
    • 0030823347 scopus 로고    scopus 로고
    • HIV-1-specific cell-mediated immune responses induced by DNA vaccination were enhanced by mannan-coated liposomes and inhibited by antiinterferon-gamma antibody
    • Toda S, Ishii N, Okada E, et al. HIV-1-specific cell-mediated immune responses induced by DNA vaccination were enhanced by mannan-coated liposomes and inhibited by antiinterferon-gamma antibody. Immunology 1997; 92:111-117.
    • (1997) Immunology , vol.92 , pp. 111-117
    • Toda, S.1    Ishii, N.2    Okada, E.3
  • 54
    • 11144356241 scopus 로고    scopus 로고
    • Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA
    • Zuber AK, Brave A, Engström G, et al. Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA. Vaccine 2004; 22:1791-1798.
    • (2004) Vaccine , vol.22 , pp. 1791-1798
    • Zuber, A.K.1    Brave, A.2    Engström, G.3
  • 55
    • 43949114521 scopus 로고    scopus 로고
    • Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation
    • Liu J, Kjeken R, Mathiesen I, Barouch DH. Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation. J Virol 2008; 82:5643-5649.
    • (2008) J Virol , vol.82 , pp. 5643-5649
    • Liu, J.1    Kjeken, R.2    Mathiesen, I.3    Barouch, D.H.4
  • 56
    • 80052285787 scopus 로고    scopus 로고
    • High antibody and cellular responses induced to HIV-1 clade C envelope following DNA vaccines delivered by electroporation
    • Yin J, Dai A, Lecureux J, et al. High antibody and cellular responses induced to HIV-1 clade C envelope following DNA vaccines delivered by electroporation. Vaccine 2011; 29:6763-6770.
    • (2011) Vaccine , vol.29 , pp. 6763-6770
    • Yin, J.1    Dai, A.2    Lecureux, J.3
  • 57
    • 44749083247 scopus 로고    scopus 로고
    • Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques
    • Hirao LA, Wu L, Khan AS, et al. Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques. Vaccine 2008; 26:3112-3120.
    • (2008) Vaccine , vol.26 , pp. 3112-3120
    • Hirao, L.A.1    Wu, L.2    Khan, A.S.3
  • 58
    • 84881623207 scopus 로고    scopus 로고
    • Safety and comparative immuno-genicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery
    • Kalams SA, Parker SD, Elizaga M, et al. Safety and comparative immuno-genicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery. J Infect Dis 2013; 208:818-829.
    • (2013) J Infect Dis , vol.208 , pp. 818-829
    • Kalams, S.A.1    Parker, S.D.2    Elizaga, M.3
  • 59
    • 32344439457 scopus 로고    scopus 로고
    • Improving recombinant MVA immune responses: Potentiation of the immune responses to HIV-1 with MVA and DNA vectors expressing Env and the cytokines IL-12 and IFN-gamma
    • Abaitua F, Rodŕiguez JR, Garzón A, et al. Improving recombinant MVA immune responses: potentiation of the immune responses to HIV-1 with MVA and DNA vectors expressing Env and the cytokines IL-12 and IFN-gamma. Virus Res 2006; 116:11-20.
    • (2006) Virus Res , vol.116 , pp. 11-20
    • Abaitua, F.1    Rodŕiguez, J.R.2    Garzón, A.3
  • 60
    • 0033151996 scopus 로고    scopus 로고
    • IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 Env in a dose-dependent manner
    • Gherardi MM, Ramírez JC, Rodŕiguez D, et al. IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 Env in a dose-dependent manner. J Immunol 1999; 162:6724-6733.
    • (1999) J Immunol , vol.162 , pp. 6724-6733
    • Gherardi, M.M.1    Ramírez, J.C.2    Rodŕiguez, D.3
  • 61
    • 47149112188 scopus 로고    scopus 로고
    • CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals
    • Liu J, Yu Q, Stone GW, et al. CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals. Vaccine 2008; 26:4062-4072.
    • (2008) Vaccine , vol.26 , pp. 4062-4072
    • Liu, J.1    Yu, Q.2    Stone, G.W.3
  • 62
    • 67650762199 scopus 로고    scopus 로고
    • The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine
    • Liu J, Ngai N, Stone GW, et al. The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine. Vaccine 2009; 27:5077-5084.
    • (2009) Vaccine , vol.27 , pp. 5077-5084
    • Liu, J.1    Ngai, N.2    Stone, G.W.3
  • 63
    • 56349137195 scopus 로고    scopus 로고
    • Interferon-beta expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity
    • Faul EJ, Wanjalla CN, McGettigan JP, Schnell MJ. Interferon-beta expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity. Virology 2008; 382:226-238.
    • (2008) Virology , vol.382 , pp. 226-238
    • Faul, E.J.1    Wanjalla, C.N.2    McGettigan, J.P.3    Schnell, M.J.4
  • 64
    • 67349168133 scopus 로고    scopus 로고
    • Multimeric soluble CD40 ligand (sCD40L) efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus vectors MVA and NYVAC expressing HIV antigens
    • Gómez CE, Nájera JL, Sánchez R, et al. Multimeric soluble CD40 ligand (sCD40L) efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus vectors MVA and NYVAC expressing HIV antigens. Vaccine 2009; 27:3165-3174.
    • (2009) Vaccine , vol.27 , pp. 3165-3174
    • Gómez, C.E.1    Nájera, J.L.2    Sánchez, R.3
  • 65
    • 33846156204 scopus 로고    scopus 로고
    • Oral vaccination with modified vaccinia virus Ankara attached covalently to TMPEG-modified cationic liposomes overcomes preexisting poxvirus immunity from recombinant vaccinia immunization
    • Naito T, Kaneko Y, Kozbor D. Oral vaccination with modified vaccinia virus Ankara attached covalently to TMPEG-modified cationic liposomes overcomes preexisting poxvirus immunity from recombinant vaccinia immunization. J Gen Virol 2007; 88:61-70.
    • (2007) J Gen Virol , vol.88 , pp. 61-70
    • Naito, T.1    Kaneko, Y.2    Kozbor, D.3
  • 66
    • 79958819334 scopus 로고    scopus 로고
    • Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum-containing adjuvants on the immune response
    • Hansen B, Malyala P, Singh M, et al. Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum-containing adjuvants on the immune response. J Pharm Sci 2011; 100:3245-3250.
    • (2011) J Pharm Sci , vol.100 , pp. 3245-3250
    • Hansen, B.1    Malyala, P.2    Singh, M.3
  • 67
    • 51349115475 scopus 로고    scopus 로고
    • Induction of HIV-1 MPR(649-684)-specific IgA and IgG antibodies in caprine colostrum using a peptide-based vaccine
    • Dorosko SM, Ayres SL, Connor RI. Induction of HIV-1 MPR(649-684)-specific IgA and IgG antibodies in caprine colostrum using a peptide-based vaccine. Vaccine 2008; 26:5416-5422.
    • (2008) Vaccine , vol.26 , pp. 5416-5422
    • Dorosko, S.M.1    Ayres, S.L.2    Connor, R.I.3
  • 68
    • 31144451337 scopus 로고    scopus 로고
    • Characterization of antibody responses elicited by human immunodeficiency virustype1primaryisolate trimeric and monomeric envelope glycoproteins in selected adjuvants
    • Li Y, Svehla K, Mathy NL, et al. Characterization of antibody responses elicited by human immunodeficiency virustype1primaryisolate trimeric and monomeric envelope glycoproteins in selected adjuvants. J Virol 2006; 80:1414-1426.
    • (2006) J Virol , vol.80 , pp. 1414-1426
    • Li, Y.1    Svehla, K.2    Mathy, N.L.3
  • 69
    • 58149487629 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein
    • Mörner A, Douagi I, Forsell MNE, et al. Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein. J Virol 2009; 83:540-551.
    • (2009) J Virol , vol.83 , pp. 540-551
    • Mörner, A.1    Douagi, I.2    Mne, F.3
  • 70
    • 77957357557 scopus 로고    scopus 로고
    • Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120 Nef and Tat antigens formulated in three adjuvant systems
    • Leroux-Roels I, Koutsoukos M, Clement F, et al. Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120, Nef and Tat antigens formulated in three adjuvant systems. Vaccine 2010; 28:7016-7024.
    • (2010) Vaccine , vol.28 , pp. 7016-7024
    • Leroux-Roels, I.1    Koutsoukos, M.2    Clement, F.3
  • 71
    • 33845207796 scopus 로고    scopus 로고
    • Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multiprotein recombinant vaccine in uninfected human volunteers
    • Goepfert PA, Tomaras GD, Horton H, et al. Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multiprotein recombinant vaccine in uninfected human volunteers. Vaccine 2007; 25:510-518.
    • (2007) Vaccine , vol.25 , pp. 510-518
    • Goepfert, P.A.1    Tomaras, G.D.2    Horton, H.3
  • 72
    • 63549137349 scopus 로고    scopus 로고
    • Neutralizing antibody responses to subtype B and C adjuvanted HIV envelope protein vaccination in rabbits
    • Burke B, Gó mez-Román VR, Lian Y, et al. Neutralizing antibody responses to subtype B and C adjuvanted HIV envelope protein vaccination in rabbits. Virology 2009; 387:147-156.
    • (2009) Virology , vol.387 , pp. 147-156
    • Burke, B.1    Gómez-Román, V.R.2    Lian, Y.3
  • 73
    • 84859579668 scopus 로고    scopus 로고
    • Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants
    • Lai RPJ, Seaman MS, Tonks P, et al. Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants. PLoS One 2012; 7:e35083.
    • (2012) PLoS One , vol.7
    • Rpj, L.1    Seaman, M.S.2    Tonks, P.3
  • 74
    • 84894593765 scopus 로고    scopus 로고
    • TLR-7/8 and 9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques
    • Moody MA, Santra S, Vandergrift NA, et al. TLR-7/8 and 9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques. J Virol 2014; 88:3329-3339.
    • (2014) J Virol , vol.88 , pp. 3329-3339
    • Moody, M.A.1    Santra, S.2    Vandergrift, N.A.3
  • 75
    • 33646157934 scopus 로고    scopus 로고
    • Adjuvanticity of stealth liposomes on the immunogenicity of synthetic gp41 epitope of HIV-1
    • Singh SK, Bisen PS. Adjuvanticity of stealth liposomes on the immunogenicity of synthetic gp41 epitope of HIV-1. Vaccine 2006; 24:4161-4166.
    • (2006) Vaccine , vol.24 , pp. 4161-4166
    • Singh, S.K.1    Bisen, P.S.2
  • 76
    • 17144423210 scopus 로고    scopus 로고
    • ROv-ASP-1, a recombinant secreted protein of the helminth Onchocerca volvulus, is a potent adjuvant for inducing antibodies to ovalbumin, HIV-1 polypeptide and SARS-CoV peptide antigens
    • MacDonald AJ, Cao L, He Y, et al. rOv-ASP-1, a recombinant secreted protein of the helminth Onchocerca volvulus, is a potent adjuvant for inducing antibodies to ovalbumin, HIV-1 polypeptide and SARS-CoV peptide antigens. Vaccine 2005; 23:3446-3452.
    • (2005) Vaccine , vol.23 , pp. 3446-3452
    • Macdonald, A.J.1    Cao, L.2    He, Y.3
  • 77
    • 0026023163 scopus 로고
    • Safety and immunogenicity of a genetically engineered human immunodeficiency virus vaccine
    • Wintsch J, Chaignat CL, Braun DG, et al. Safety and immunogenicity of a genetically engineered human immunodeficiency virus vaccine. J Infect Dis 1991; 163:219-225.
    • (1991) J Infect Dis , vol.163 , pp. 219-225
    • Wintsch, J.1    Chaignat, C.L.2    Braun, D.G.3
  • 78
    • 9244255773 scopus 로고    scopus 로고
    • Safety and immunogenicity of Env 2-3, a human immunodeficiency virus type 1 candidate vaccine, in combination with a novel adjuvant, MTP-PE/MF59, NIAID AIDS Vaccine Evaluation Group
    • Keefer MC, Graham BS, McElrath MJ, et al. Safety and immunogenicity of Env 2-3, a human immunodeficiency virus type 1 candidate vaccine, in combination with a novel adjuvant, MTP-PE/MF59. NIAID AIDS Vaccine Evaluation Group. AIDS Res Hum Retroviruses 1996; 12:683-693.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 683-693
    • Keefer, M.C.1    Graham, B.S.2    McElrath, M.J.3
  • 79
    • 0033988471 scopus 로고    scopus 로고
    • A phase i trial in HIV negative healthy volunteers evaluating the effect of potent adjuvants on immunogenicity of a recombinant gp120W61D derived from dual tropic R5X4 HIV-1ACH320
    • McCormack S, Tilzey A, Carmichael A, et al. A phase I trial in HIV negative healthy volunteers evaluating the effect of potent adjuvants on immunogenicity of a recombinant gp120W61D derived from dual tropic R5X4 HIV-1ACH320. Vaccine 2000; 18:1166-1177.
    • (2000) Vaccine , vol.18 , pp. 1166-1177
    • McCormack, S.1    Tilzey, A.2    Carmichael, A.3
  • 80
    • 4444309788 scopus 로고    scopus 로고
    • Phase I/II study of a candidate vaccine designed against the B and e subtypes of HIV-1
    • Pitisuttithum P, Berman PW, Phonrat B, et al. Phase I/II study of a candidate vaccine designed against the B and E subtypes of HIV-1. J Acquir Immune Defic Syndr 2004; 37:1160-1165.
    • (2004) J Acquir Immune Defic Syndr , vol.37 , pp. 1160-1165
    • Pitisuttithum, P.1    Berman, P.W.2    Phonrat, B.3
  • 81
    • 9144264269 scopus 로고    scopus 로고
    • A novel adjuvant for mucosal immunity to HIV-1 gp120 in nonhuman primates
    • Yoshino N, Lü FX-S, Fujihashi K, et al. A novel adjuvant for mucosal immunity to HIV-1 gp120 in nonhuman primates. J Immunol 2004; 173:6850-6857.
    • (2004) J Immunol , vol.173 , pp. 6850-6857
    • Yoshino, N.1    Fx-S, L.2    Fujihashi, K.3
  • 82
    • 58149401439 scopus 로고    scopus 로고
    • CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1envelope glycoproteins following mucosal immunization
    • Sundling C, Schön K, Mörner A, et al. CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1envelope glycoproteins following mucosal immunization. J Gen Virol 2008; 89:2954-2964.
    • (2008) J Gen Virol , vol.89 , pp. 2954-2964
    • Sundling, C.1    Schön, K.2    Mörner, A.3
  • 83
    • 33745698593 scopus 로고    scopus 로고
    • Capric acid and hydroxypropylmethylcellulose increase the immunogenicity of nasally administered peptide vaccines
    • Nordone SK, Peacock JW, Kirwan SM, Staats HF. Capric acid and hydroxypropylmethylcellulose increase the immunogenicity of nasally administered peptide vaccines. AIDS Res Hum Retroviruses 2006; 22:558-568.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , pp. 558-568
    • Nordone, S.K.1    Peacock, J.W.2    Kirwan, S.M.3    Staats, H.F.4
  • 84
    • 4143052489 scopus 로고    scopus 로고
    • A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques
    • Egan MA, Chong SY, Hagen M, et al. A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques. Vaccine 2004; 22:3774-3788.
    • (2004) Vaccine , vol.22 , pp. 3774-3788
    • Egan, M.A.1    Chong, S.Y.2    Hagen, M.3
  • 85
    • 0036140236 scopus 로고    scopus 로고
    • Cytokines as adjuvants for the induction of antihuman immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization
    • Bradney CP, Sempowski GD, Liao H-X, et al. Cytokines as adjuvants for the induction of antihuman immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization. J Virol 2002; 76:517-524.
    • (2002) J Virol , vol.76 , pp. 517-524
    • Bradney, C.P.1    Sempowski, G.D.2    Liao, H.-X.3
  • 86
    • 39549118132 scopus 로고    scopus 로고
    • Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates
    • Bielinska AU, Janczak KW, Landers JJ, et al. Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates. AIDS Res Hum Retroviruses 2008; 24:271-281.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , pp. 271-281
    • Bielinska, A.U.1    Janczak, K.W.2    Landers, J.J.3
  • 87
    • 0037744877 scopus 로고    scopus 로고
    • Efficient mucosal delivery of the HIV-1 Tat protein using the synthetic lipopeptide MALP-2 as adjuvant
    • Borsutzky S, Fiorelli V, Ebensen T, et al. Efficient mucosal delivery of the HIV-1 Tat protein using the synthetic lipopeptide MALP-2 as adjuvant. Eur J Immunol 2003; 33:1548-1556.
    • (2003) Eur J Immunol , vol.33 , pp. 1548-1556
    • Borsutzky, S.1    Fiorelli, V.2    Ebensen, T.3
  • 88
    • 32844467862 scopus 로고    scopus 로고
    • Efficient systemic and mucosal responses against the HIV-1 Tat protein by prime/boost vaccination using the lipopeptide MALP-2 as adjuvant
    • Borsutzky S, Ebensen T, Link C, et al. Efficient systemic and mucosal responses against the HIV-1 Tat protein by prime/boost vaccination using the lipopeptide MALP-2 as adjuvant. Vaccine 2006; 24:2049-2056.
    • (2006) Vaccine , vol.24 , pp. 2049-2056
    • Borsutzky, S.1    Ebensen, T.2    Link, C.3
  • 89
    • 79151476447 scopus 로고    scopus 로고
    • Antibody responses after intravaginal immunisation with trimeric HIV-1 CN54 clade C gp140 in Carbopol gel are augmented by systemic priming or boosting with an adjuvanted formulation
    • Cranage MP, Fraser CA, Cope A, et al. Antibody responses after intravaginal immunisation with trimeric HIV-1 CN54 clade C gp140 in Carbopol gel are augmented by systemic priming or boosting with an adjuvanted formulation. Vaccine 2011; 29:1421-1430.
    • (2011) Vaccine , vol.29 , pp. 1421-1430
    • Cranage, M.P.1    Fraser, C.A.2    Cope, A.3
  • 90
    • 84856045473 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin (TSLP) acts as a potent mucosal adjuvant for HIV-1 gp140 vaccination in mice
    • Van Roey GA, Arias MA, Tregoning JS, et al. Thymic stromal lymphopoietin (TSLP) acts as a potent mucosal adjuvant for HIV-1 gp140 vaccination in mice. Eur J Immunol 2012; 42:353-363.
    • (2012) Eur J Immunol , vol.42 , pp. 353-363
    • Van Roey, G.A.1    Arias, M.A.2    Tregoning, J.S.3
  • 91
    • 84865597206 scopus 로고    scopus 로고
    • Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations
    • Pattani A, McKay PF, Garland MJ, et al. Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations. J Control Release 2012; 162:529-537.
    • (2012) J Control Release , vol.162 , pp. 529-537
    • Pattani, A.1    McKay, P.F.2    Garland, M.J.3
  • 92
    • 84855342224 scopus 로고    scopus 로고
    • Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques
    • Rosario M, Borthwick N, Stewart-Jones GB, et al. Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques. AIDS 2012; 26:275-284.
    • (2012) AIDS , vol.26 , pp. 275-284
    • Rosario, M.1    Borthwick, N.2    Stewart-Jones, G.B.3
  • 93
    • 77952688015 scopus 로고    scopus 로고
    • Antibody-mediated protection against mucosal simian-human immunodeficiency virus challenge of macaques immunized with alphavirus replicon particles and boosted with trimeric envelope glycoprotein in MF59 adjuvant
    • Barnett SW, Burke B, Sun Y, et al. Antibody-mediated protection against mucosal simian-human immunodeficiency virus challenge of macaques immunized with alphavirus replicon particles and boosted with trimeric envelope glycoprotein in MF59 adjuvant. J Virol 2010; 84:5975-5985.
    • (2010) J Virol , vol.84 , pp. 5975-5985
    • Barnett, S.W.1    Burke, B.2    Sun, Y.3
  • 94
    • 0033523051 scopus 로고    scopus 로고
    • A prime-boost regime that combines Montanide ISA720 and Alhydrogel to induce antibodies against the HIV-1 derived multiepitope polypeptide TAB9
    • Raya NE, Quintana D, Carrazana Y, et al. A prime-boost regime that combines Montanide ISA720 and Alhydrogel to induce antibodies against the HIV-1 derived multiepitope polypeptide TAB9. Vaccine 1999; 17: 2646-2650.
    • (1999) Vaccine , vol.17 , pp. 2646-2650
    • Raya, N.E.1    Quintana, D.2    Carrazana, Y.3
  • 95
    • 0028136202 scopus 로고
    • Bumps on the vaccine road
    • Cohen J. Bumps on the vaccine road. Science 1994; 265:1371-1373.
    • (1994) Science , vol.265 , pp. 1371-1373
    • Cohen, J.1


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