메뉴 건너뛰기




Volumn 27, Issue 37, 2009, Pages 5077-5084

The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine

Author keywords

Adjuvant; AIDS; Canarypox vector

Indexed keywords

ADJUVANT; CD134 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; OX40 LIGAND; UNCLASSIFIED DRUG; VCP1452 VACCINE; VIRUS VECTOR;

EID: 67650762199     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.06.046     Document Type: Article
Times cited : (13)

References (48)
  • 2
    • 33845207660 scopus 로고    scopus 로고
    • Progress and obstacles in the development of an AIDS vaccine
    • Letvin N.L. Progress and obstacles in the development of an AIDS vaccine. Nat Rev Immunol 6 12 (2006) 930-939
    • (2006) Nat Rev Immunol , vol.6 , Issue.12 , pp. 930-939
    • Letvin, N.L.1
  • 3
    • 36148973173 scopus 로고    scopus 로고
    • HIV/AIDS vaccines: 2007
    • Robinson H.L. HIV/AIDS vaccines: 2007. Clin Pharmacol Ther 82 6 (2007) 686-693
    • (2007) Clin Pharmacol Ther , vol.82 , Issue.6 , pp. 686-693
    • Robinson, H.L.1
  • 4
    • 38749096240 scopus 로고    scopus 로고
    • The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
    • Sekaly R.P. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?. J Exp Med 205 1 (2008) 7-12
    • (2008) J Exp Med , vol.205 , Issue.1 , pp. 7-12
    • Sekaly, R.P.1
  • 5
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts T.H. TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 23 (2005) 23-68
    • (2005) Annu Rev Immunol , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 6
    • 2942592429 scopus 로고    scopus 로고
    • Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40
    • Sugamura K., Ishii N., and Weinberg A.D. Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40. Nat Rev Immunol 4 6 (2004) 420-431
    • (2004) Nat Rev Immunol , vol.4 , Issue.6 , pp. 420-431
    • Sugamura, K.1    Ishii, N.2    Weinberg, A.D.3
  • 7
    • 0034812971 scopus 로고    scopus 로고
    • OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
    • Rogers P.R., Song J., Gramaglia I., Killeen N., and Croft M. OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 15 3 (2001) 445-455
    • (2001) Immunity , vol.15 , Issue.3 , pp. 445-455
    • Rogers, P.R.1    Song, J.2    Gramaglia, I.3    Killeen, N.4    Croft, M.5
  • 8
    • 1142263117 scopus 로고    scopus 로고
    • The costimulation-regulated duration of PKB activation controls T cell longevity
    • Song J., Salek-Ardakani S., Rogers P.R., Cheng M., Van Parijs L., and Croft M. The costimulation-regulated duration of PKB activation controls T cell longevity. Nat Immunol 5 2 (2004) 150-158
    • (2004) Nat Immunol , vol.5 , Issue.2 , pp. 150-158
    • Song, J.1    Salek-Ardakani, S.2    Rogers, P.R.3    Cheng, M.4    Van Parijs, L.5    Croft, M.6
  • 9
  • 10
    • 34250358993 scopus 로고    scopus 로고
    • Cooperation between CD4 and CD8 T cells for anti-tumor activity is enhanced by OX40 signals
    • Song A., Song J., Tang X., and Croft M. Cooperation between CD4 and CD8 T cells for anti-tumor activity is enhanced by OX40 signals. Eur J Immunol 37 5 (2007) 1224-1232
    • (2007) Eur J Immunol , vol.37 , Issue.5 , pp. 1224-1232
    • Song, A.1    Song, J.2    Tang, X.3    Croft, M.4
  • 11
    • 33749128681 scopus 로고    scopus 로고
    • Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses
    • Lee S.W., Park Y., Song A., Cheroutre H., Kwon B.S., and Croft M. Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses. J Immunol 177 7 (2006) 4464-4472
    • (2006) J Immunol , vol.177 , Issue.7 , pp. 4464-4472
    • Lee, S.W.1    Park, Y.2    Song, A.3    Cheroutre, H.4    Kwon, B.S.5    Croft, M.6
  • 12
    • 38849164304 scopus 로고    scopus 로고
    • Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist
    • Redmond W.L., Gough M.J., Charbonneau B., Ratliff T.L., and Weinberg A.D. Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist. J Immunol 179 11 (2007) 7244-7253
    • (2007) J Immunol , vol.179 , Issue.11 , pp. 7244-7253
    • Redmond, W.L.1    Gough, M.J.2    Charbonneau, B.3    Ratliff, T.L.4    Weinberg, A.D.5
  • 13
    • 36048956341 scopus 로고    scopus 로고
    • OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice
    • Zaini J., Andarini S., Tahara M., Saijo Y., Ishii N., Kawakami K., et al. OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice. J Clin Invest 117 11 (2007) 3330-3338
    • (2007) J Clin Invest , vol.117 , Issue.11 , pp. 3330-3338
    • Zaini, J.1    Andarini, S.2    Tahara, M.3    Saijo, Y.4    Ishii, N.5    Kawakami, K.6
  • 14
    • 27744446078 scopus 로고    scopus 로고
    • Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: comparison with B7, 1 and 4-1BBL
    • Serghides L., Bukczynski J., Wen T., Wang C., Routy J.P., Boulassel M.R., et al. Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: comparison with B7, 1 and 4-1BBL. J Immunol 175 10 (2005) 6368-6377
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 6368-6377
    • Serghides, L.1    Bukczynski, J.2    Wen, T.3    Wang, C.4    Routy, J.P.5    Boulassel, M.R.6
  • 15
    • 32144453848 scopus 로고    scopus 로고
    • OX40 ligation of CD4+ T cells enhances virus-specific CD8+ T cell memory responses independently of IL-2 and CD4+ T regulatory cell inhibition
    • Yu Q., Yue F.Y., Gu X.X., Schwartz H., Kovacs C.M., and Ostrowski M.A. OX40 ligation of CD4+ T cells enhances virus-specific CD8+ T cell memory responses independently of IL-2 and CD4+ T regulatory cell inhibition. J Immunol 176 4 (2006) 2486-2495
    • (2006) J Immunol , vol.176 , Issue.4 , pp. 2486-2495
    • Yu, Q.1    Yue, F.Y.2    Gu, X.X.3    Schwartz, H.4    Kovacs, C.M.5    Ostrowski, M.A.6
  • 17
    • 0027209868 scopus 로고
    • Induction of cytotoxic T lymphocytes by recombinant canarypox (ALVAC) and attenuated vaccinia (NYVAC) viruses expressing the HIV-1 envelope glycoprotein
    • Cox W.I., Tartaglia J., and Paoletti E. Induction of cytotoxic T lymphocytes by recombinant canarypox (ALVAC) and attenuated vaccinia (NYVAC) viruses expressing the HIV-1 envelope glycoprotein. Virology 195 2 (1993) 845-850
    • (1993) Virology , vol.195 , Issue.2 , pp. 845-850
    • Cox, W.I.1    Tartaglia, J.2    Paoletti, E.3
  • 18
    • 11444256172 scopus 로고    scopus 로고
    • HIV-1 prophylactic vaccine trials in Thailand
    • Pitisuttithum P. HIV-1 prophylactic vaccine trials in Thailand. Curr HIV Res 3 1 (2005) 17-30
    • (2005) Curr HIV Res , vol.3 , Issue.1 , pp. 17-30
    • Pitisuttithum, P.1
  • 19
    • 4344679417 scopus 로고    scopus 로고
    • ALVAC-HIV vaccines: clinical trial experience focusing on progress in vaccine development
    • Marovich M.A. ALVAC-HIV vaccines: clinical trial experience focusing on progress in vaccine development. Expert Rev Vaccines 3 Suppl. 4 (2004) S99-104
    • (2004) Expert Rev Vaccines , vol.3 , Issue.SUPPL. 4
    • Marovich, M.A.1
  • 21
    • 34247248864 scopus 로고    scopus 로고
    • Use of viral vectors for the development of vaccines
    • Liniger M., Zuniga A., and Naim H.Y. Use of viral vectors for the development of vaccines. Expert Rev Vaccines 6 2 (2007) 255-266
    • (2007) Expert Rev Vaccines , vol.6 , Issue.2 , pp. 255-266
    • Liniger, M.1    Zuniga, A.2    Naim, H.Y.3
  • 22
    • 7144259087 scopus 로고    scopus 로고
    • Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group.
    • Clements-Mann M.L., Weinhold K., Matthews T.J., Graham B.S., Gorse G.J., Keefer M.C., et al. Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group. J Infect Dis 177 5 (1998) 1230-1246
    • (1998) J Infect Dis , vol.177 , Issue.5 , pp. 1230-1246
    • Clements-Mann, M.L.1    Weinhold, K.2    Matthews, T.J.3    Graham, B.S.4    Gorse, G.J.5    Keefer, M.C.6
  • 23
    • 34748888347 scopus 로고    scopus 로고
    • Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120
    • Cleghorn F., Pape J.W., Schechter M., Bartholomew C., Sanchez J., Jack N., et al. Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120. J Acquir Immune Defic Syndr 46 2 (2007) 222-230
    • (2007) J Acquir Immune Defic Syndr , vol.46 , Issue.2 , pp. 222-230
    • Cleghorn, F.1    Pape, J.W.2    Schechter, M.3    Bartholomew, C.4    Sanchez, J.5    Jack, N.6
  • 24
    • 34848908400 scopus 로고    scopus 로고
    • A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost
    • Thongcharoen P., Suriyanon V., Paris R.M., Khamboonruang C., de Souza M.S., Ratto-Kim S., et al. A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost. J Acquir Immune Defic Syndr 46 1 (2007) 48-55
    • (2007) J Acquir Immune Defic Syndr , vol.46 , Issue.1 , pp. 48-55
    • Thongcharoen, P.1    Suriyanon, V.2    Paris, R.M.3    Khamboonruang, C.4    de Souza, M.S.5    Ratto-Kim, S.6
  • 25
    • 25444525193 scopus 로고    scopus 로고
    • High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects
    • Goepfert P.A., Horton H., McElrath M.J., Gurunathan S., Ferrari G., Tomaras G.D., et al. High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects. J Infect Dis 192 7 (2005) 1249-1259
    • (2005) J Infect Dis , vol.192 , Issue.7 , pp. 1249-1259
    • Goepfert, P.A.1    Horton, H.2    McElrath, M.J.3    Gurunathan, S.4    Ferrari, G.5    Tomaras, G.D.6
  • 26
    • 47149112188 scopus 로고    scopus 로고
    • CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals
    • Liu J., Yu Q., Stone G.W., Yue F.Y., Ngai N., Jones R.B., et al. CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals. Vaccine 26 32 (2008) 4062-4072
    • (2008) Vaccine , vol.26 , Issue.32 , pp. 4062-4072
    • Liu, J.1    Yu, Q.2    Stone, G.W.3    Yue, F.Y.4    Ngai, N.5    Jones, R.B.6
  • 27
    • 0035692405 scopus 로고    scopus 로고
    • Expression of vaccinia E3L and K3L genes by a novel recombinant canarypox HIV vaccine vector enhances HIV-1 pseudovirion production and inhibits apoptosis in human cells
    • Fang Z.Y., Limbach K., Tartaglia J., Hammonds J., Chen X., and Spearman P. Expression of vaccinia E3L and K3L genes by a novel recombinant canarypox HIV vaccine vector enhances HIV-1 pseudovirion production and inhibits apoptosis in human cells. Virology 291 2 (2001) 272-284
    • (2001) Virology , vol.291 , Issue.2 , pp. 272-284
    • Fang, Z.Y.1    Limbach, K.2    Tartaglia, J.3    Hammonds, J.4    Chen, X.5    Spearman, P.6
  • 28
    • 0034699367 scopus 로고    scopus 로고
    • Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons A.B. Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J Immunol Methods 243 1-2 (2000) 147-154
    • (2000) J Immunol Methods , vol.243 , Issue.1-2 , pp. 147-154
    • Lyons, A.B.1
  • 29
    • 1842681952 scopus 로고    scopus 로고
    • Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets
    • Huster K.M., Busch V., Schiemann M., Linkemann K., Kerksiek K.M., Wagner H., et al. Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. Proc Natl Acad Sci U.S.A. 101 15 (2004) 5610-5615
    • (2004) Proc Natl Acad Sci U.S.A. , vol.101 , Issue.15 , pp. 5610-5615
    • Huster, K.M.1    Busch, V.2    Schiemann, M.3    Linkemann, K.4    Kerksiek, K.M.5    Wagner, H.6
  • 30
    • 25444461647 scopus 로고    scopus 로고
    • Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L
    • Bachmann M.F., Wolint P., Schwarz K., Jager P., and Oxenius A. Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L. J Immunol 175 7 (2005) 4686-4696
    • (2005) J Immunol , vol.175 , Issue.7 , pp. 4686-4696
    • Bachmann, M.F.1    Wolint, P.2    Schwarz, K.3    Jager, P.4    Oxenius, A.5
  • 31
    • 33745345216 scopus 로고    scopus 로고
    • Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells
    • Huster K.M., Koffler M., Stemberger C., Schiemann M., Wagner H., and Busch D.H. Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells. Eur J Immunol 36 6 (2006) 1453-1464
    • (2006) Eur J Immunol , vol.36 , Issue.6 , pp. 1453-1464
    • Huster, K.M.1    Koffler, M.2    Stemberger, C.3    Schiemann, M.4    Wagner, H.5    Busch, D.H.6
  • 32
    • 33846399187 scopus 로고    scopus 로고
    • Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survival and significantly increases recall responses
    • Ruby C.E., Redmond W.L., Haley D., and Weinberg A.D. Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survival and significantly increases recall responses. Eur J Immunol 37 1 (2007) 157-166
    • (2007) Eur J Immunol , vol.37 , Issue.1 , pp. 157-166
    • Ruby, C.E.1    Redmond, W.L.2    Haley, D.3    Weinberg, A.D.4
  • 34
    • 34250327922 scopus 로고    scopus 로고
    • Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses
    • Precopio M.L., Betts M.R., Parrino J., Price D.A., Gostick E., Ambrozak D.R., et al. Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 204 6 (2007) 1405-1416
    • (2007) J Exp Med , vol.204 , Issue.6 , pp. 1405-1416
    • Precopio, M.L.1    Betts, M.R.2    Parrino, J.3    Price, D.A.4    Gostick, E.5    Ambrozak, D.R.6
  • 35
    • 42149095015 scopus 로고    scopus 로고
    • IL-12 is required for anti-OX40-mediated CD4 T cell survival
    • Ruby C.E., Montler R., Zheng R., Shu S., and Weinberg A.D. IL-12 is required for anti-OX40-mediated CD4 T cell survival. J Immunol 180 4 (2008) 2140-2148
    • (2008) J Immunol , vol.180 , Issue.4 , pp. 2140-2148
    • Ruby, C.E.1    Montler, R.2    Zheng, R.3    Shu, S.4    Weinberg, A.D.5
  • 36
    • 38449090407 scopus 로고    scopus 로고
    • Differential requirements for OX40 signals on generation of effector and central memory CD4+ T cells
    • Soroosh P., Ine S., Sugamura K., and Ishii N. Differential requirements for OX40 signals on generation of effector and central memory CD4+ T cells. J Immunol 179 8 (2007) 5014-5023
    • (2007) J Immunol , vol.179 , Issue.8 , pp. 5014-5023
    • Soroosh, P.1    Ine, S.2    Sugamura, K.3    Ishii, N.4
  • 37
    • 31844446946 scopus 로고    scopus 로고
    • Regulation of CD4 T cell memory by OX40 (CD134)
    • Salek-Ardakani S., and Croft M. Regulation of CD4 T cell memory by OX40 (CD134). Vaccine 24 7 (2006) 872-883
    • (2006) Vaccine , vol.24 , Issue.7 , pp. 872-883
    • Salek-Ardakani, S.1    Croft, M.2
  • 39
    • 0029045255 scopus 로고
    • Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
    • Stuber E., Neurath M., Calderhead D., Fell H.P., and Strober W. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity 2 5 (1995) 507-521
    • (1995) Immunity , vol.2 , Issue.5 , pp. 507-521
    • Stuber, E.1    Neurath, M.2    Calderhead, D.3    Fell, H.P.4    Strober, W.5
  • 40
    • 0029938992 scopus 로고    scopus 로고
    • The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response
    • Stuber E., and Strober W. The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response. J Exp Med 183 3 (1996) 979-989
    • (1996) J Exp Med , vol.183 , Issue.3 , pp. 979-989
    • Stuber, E.1    Strober, W.2
  • 41
    • 0034677176 scopus 로고    scopus 로고
    • Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand
    • Murata K., Ishii N., Takano H., Miura S., Ndhlovu L.C., Nose M., et al. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J Exp Med 191 2 (2000) 365-374
    • (2000) J Exp Med , vol.191 , Issue.2 , pp. 365-374
    • Murata, K.1    Ishii, N.2    Takano, H.3    Miura, S.4    Ndhlovu, L.C.5    Nose, M.6
  • 42
    • 0038066310 scopus 로고    scopus 로고
    • CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells
    • Kim M.Y., Gaspal F.M., Wiggett H.E., McConnell F.M., Gulbranson-Judge A., Raykundalia C., et al. CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Immunity 18 5 (2003) 643-654
    • (2003) Immunity , vol.18 , Issue.5 , pp. 643-654
    • Kim, M.Y.1    Gaspal, F.M.2    Wiggett, H.E.3    McConnell, F.M.4    Gulbranson-Judge, A.5    Raykundalia, C.6
  • 43
    • 0344286707 scopus 로고    scopus 로고
    • Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)
    • Pippig S.D., Pena-Rossi C., Long J., Godfrey W.R., Fowell D.J., Reiner S.L., et al. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J Immunol 163 12 (1999) 6520-6529
    • (1999) J Immunol , vol.163 , Issue.12 , pp. 6520-6529
    • Pippig, S.D.1    Pena-Rossi, C.2    Long, J.3    Godfrey, W.R.4    Fowell, D.J.5    Reiner, S.L.6
  • 44
    • 0033427044 scopus 로고    scopus 로고
    • Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions
    • Chen A.I., McAdam A.J., Buhlmann J.E., Scott S., Lupher Jr. M.L., Greenfield E.A., et al. Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions. Immunity 11 6 (1999) 689-698
    • (1999) Immunity , vol.11 , Issue.6 , pp. 689-698
    • Chen, A.I.1    McAdam, A.J.2    Buhlmann, J.E.3    Scott, S.4    Lupher Jr., M.L.5    Greenfield, E.A.6
  • 45
    • 0033427047 scopus 로고    scopus 로고
    • OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection
    • Kopf M., Ruedl C., Schmitz N., Gallimore A., Lefrang K., Ecabert B., et al. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity 11 6 (1999) 699-708
    • (1999) Immunity , vol.11 , Issue.6 , pp. 699-708
    • Kopf, M.1    Ruedl, C.2    Schmitz, N.3    Gallimore, A.4    Lefrang, K.5    Ecabert, B.6
  • 46
    • 0034544564 scopus 로고    scopus 로고
    • IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microglia
    • Nguyen V.T., and Benveniste E.N. IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microglia. J Immunol 165 11 (2000) 6235-6243
    • (2000) J Immunol , vol.165 , Issue.11 , pp. 6235-6243
    • Nguyen, V.T.1    Benveniste, E.N.2
  • 47
    • 34848866873 scopus 로고    scopus 로고
    • CD134 costimulation couples the CD137 pathway to induce production of supereffector CD8 T cells that become IL-7 dependent
    • Lee S.J., Rossi R.J., Lee S.K., Croft M., Kwon B.S., Mittler R.S., et al. CD134 costimulation couples the CD137 pathway to induce production of supereffector CD8 T cells that become IL-7 dependent. J Immunol 179 4 (2007) 2203-2214
    • (2007) J Immunol , vol.179 , Issue.4 , pp. 2203-2214
    • Lee, S.J.1    Rossi, R.J.2    Lee, S.K.3    Croft, M.4    Kwon, B.S.5    Mittler, R.S.6
  • 48
    • 0034953586 scopus 로고    scopus 로고
    • OX40 stimulation by gp34/OX40 ligand enhances productive human immunodeficiency virus type 1 infection
    • Takahashi Y., Tanaka Y., Yamashita A., Koyanagi Y., Nakamura M., and Yamamoto N. OX40 stimulation by gp34/OX40 ligand enhances productive human immunodeficiency virus type 1 infection. J Virol 75 15 (2001) 6748-6757
    • (2001) J Virol , vol.75 , Issue.15 , pp. 6748-6757
    • Takahashi, Y.1    Tanaka, Y.2    Yamashita, A.3    Koyanagi, Y.4    Nakamura, M.5    Yamamoto, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.