Molecular imaging for assessment of mesenchymal stem cells mediated breast cancer therapy

Biomaterials

Volumn 35, Issue 19, 2014, Pages 5162-5170

  Leng, Liang ^a,b   Wang, Yuebing ^a   He, Ningning ^a   Wang, Di ^a   Zhao, Qianjie ^a   Feng, Guowei ^a   Su, Weijun ^a   Xu, Yang ^a   Han, Zhongchao ^c   Kong, Deling ^b   Cheng, Zhen ^d   Xiang, Rong ^a   Li, Zongjin ^a,b  

^a NANKAI UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

^c INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bioluminescence imaging (BLI); Cancer therapy; Mesenchymal stem cells (MSCs); Molecular imaging; Near infrared (NIF) imaging

Indexed keywords

ANTIVIRAL AGENTS; BIOLUMINESCENCE; CELL DEATH; DISEASES; FLOWCHARTING; FLUORESCENCE; GENES; INFRARED DEVICES; MAMMALS; MOLECULAR IMAGING; ONCOLOGY; PHOSPHORESCENCE; PROTEINS; STEM CELLS; TUMORS; VIRUSES;

ANTI-CANCER THERAPIES; BIOLUMINESCENCE IMAGING; CANCER THERAPY; ENHANCED GREEN FLUORESCENT PROTEIN; MESENCHYMAL STEM CELL; NEAR INFRARED; RED FLUORESCENT PROTEINS; TUMOR MICROENVIRONMENT;

CELL CULTURE;

ENHANCED GREEN FLUORESCENT PROTEIN; FIREFLY LUCIFERASE; GANCICLOVIR; RED FLUORESCENT PROTEIN; RENILLA LUCIFERIN 2 MONOOXYGENASE; THYMIDINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOLUMINESCENCE; BREAST CANCER; BYSTANDER EFFECT; CANCER INHIBITION; CANCER THERAPY; CELL DEATH; CELL PROLIFERATION; CELL TRACKING; CONTROLLED STUDY; FEMALE; FUSION GENE; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IN VIVO STUDY; MESENCHYMAL STEM CELL TRANSPLANTATION; MOLECULAR IMAGING; MOUSE; NEAR INFRARED IMAGING SYSTEM; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; TUMOR CELL; UMBILICAL CORD; ANIMAL; BREAST NEOPLASMS; CELL MOTION; CELL SURVIVAL; CYTOLOGY; MESENCHYMAL STROMA CELL; NICK END LABELING; NUDE MOUSE; PHYSIOLOGY; PROCEDURES; TUMOR CELL LINE;

MUS; RENILLA LUCIFERASE; SIMPLEXVIRUS;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; HUMANS; IN SITU NICK-END LABELING; MESENCHYMAL STROMAL CELLS; MICE; MICE, NUDE; MOLECULAR IMAGING;

EID: 84898406292     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.03.014     Document Type: Article

References (31)

1. Kucerova L., Matuskova M., Hlubinova K., Altanerova V., Altaner C. Tumor cell behaviour modulation by mesenchymal stromal cells. Mol Cancer 2010, 9:129.
2. Yong R.L., Shinojima N., Fueyo J., Gumin J., Vecil G.G., Marini F.C., et al. Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus δ24-RGD to human gliomas. Cancer Res 2009, 69:8932-8940.
3. Kidd S., Caldwell L., Dietrich M., Samudio I., Spaeth E.L., Watson K., et al. Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors invivo, an effect countered by anti-inflammatory treatment. Cytotherapy 2010, 12:615-625.
4. Nakamizo A., Marini F., Amano T., Khan A., Studeny M., Gumin J., et al. Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 2005, 65:3307-3318.
5. Mader E.K., Maeyama Y., Lin Y., Butler G.W., Russell H.M., Galanis E., et al. Mesenchymal stem cell carriers protect oncolytic measles viruses from antibody neutralization in an orthotopic ovarian cancer therapy model. Clin Cancer Res 2009, 15:7246-7255.
6. Josiah D.T., Zhu D., Dreher F., Olson J., McFadden G., Caldas H. Adipose-derived stem cells as therapeutic delivery vehicles of an oncolytic virus for glioblastoma. Mol Ther 2009, 18:377-385.
7. Dwyer R.M., Khan S., Barry F.P., O'Brien T., Kerin M.J. Advances in mesenchymal stem cell-mediated gene therapy for cancer. Stem Cell Res Ther 2010, 1:25.
8. Fillat C., Carrio M., Cascante A., Sangro B. Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/ganciclovir system: fifteen years of application. Curr Gene Ther 2003, 3:13-26.
9. Su W., Wang L., Zhou M., Liu Z., Hu S., Tong L., et al. Human embryonic stem cell-derived endothelial cells as cellular delivery vehicles for treatment of metastatic breast cancer. Cell Transplant 2013, 22:2079-2090.
10. Zhou M., Wang L., Su W., Tong L., Liu Y., Fan Y., et al. Assessment of therapeutic efficacy of liposomal nanoparticles mediated gene delivery by molecular imaging for cancer therapy. JBiomed Nanotechnol 2012, 8:742-750.
11. Wang L., Su W., Liu Z., Zhou M., Chen S., Chen Y., et al. CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma. Biomaterials 2012, 33:5107-5114.
12. Wang L., Wang Y., Li Z. Nanoparticle-based tumor theranostics with molecular imaging. Curr Pharm Biotechnol 2013, 14:683-692.
13. Weissleder R. Molecular imaging in cancer. Science 2006, 312:1168-1171.
14. Keren S., Zavaleta C., Cheng Z., de la Zerda A., Gheysens O., Gambhir S.S. Noninvasive molecular imaging of small living subjects using Raman spectroscopy. Proc Natl Acad Sci U S A 2008, 105:5844-5849.
15. Yang Z.X., Han Z.B., Ji Y.R., Wang Y.W., Liang L., Chi Y., et al. CD106 identifies a subpopulation of mesenchymal stem cells with unique immunomodulatory properties. PLoS One 2013, 8:e59354.
16. Wang Y., Zhang Z., Chi Y., Zhang Q., Xu F., Yang Z., et al. Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation. Cell Death Dis 2013, 4:e950.
17. Li Z., Wilson K.D., Smith B., Kraft D.L., Jia F., Huang M., et al. Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction. PLoS One 2009, 4:e8443.
18. Specht J.M., Mankoff D.A. Advances in molecular imaging for breast cancer detection and characterization. Breast Cancer Res 2012, 14:206.
19. Ruoslahti E. RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol 1996, 12:697-715.
20. Schiffelers R.M., Koning G.A., ten Hagen T.L., Fens M.H., Schraa A.J., Janssen A.P., et al. Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin. JControl Release 2003, 91:115-122.
21. Niu G., Chen X. Apoptosis imaging: beyond annexin V. JNucl Med 2010, 51:1659-1662.
22. Ho I.A., Toh H.C., Ng W.H., Teo Y.L., Guo C.M., Hui K.M., et al. Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis. Stem Cells 2013, 31:146-155.
23. Ma Y., Hao X., Zhang S., Zhang J. The invitro and invivo effects of human umbilical cord mesenchymal stem cells on the growth of breast cancer cells. Breast Cancer Res Treat 2012, 133:473-485.
24. Klopp A.H., Gupta A., Spaeth E., Andreeff M., Marini F. Concise review: dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth?. Stem Cells 2011, 29:11-19.
25. Torsvik A., Bjerkvig R. Mesenchymal stem cell signaling in cancer progression. Cancer Treat Rev 2013, 39:180-188.
26. Akimoto K., Kimura K., Nagano M., Takano S., To'a Salazar G., Yamashita T., et al. Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation. Stem Cells Dev 2013, 22:1370-1386.
27. Keramidas M., de Fraipont F., Karageorgis A., Moisan A., Persoons V., Richard M.J., et al. The dual effect of mesenchymal stem cells on tumour growth and tumour angiogenesis. Stem Cell Res Ther 2013, 4:41.
28. Martinez-Quintanilla J., Bhere D., Heidari P., He D., Mahmood U., Shah K. Therapeutic efficacy and fate of bimodal engineered stem cells in malignant brain tumors. Stem Cells 2013, 31:1706-1714.
29. Keung E.Z., Nelson P.J., Conrad C. Concise review: genetically engineered stem cell therapy targeting angiogenesis and tumor stroma in gastrointestinal malignancy. Stem Cells 2013, 31:227-235.
30. Dai L.J., Sun X.Y., Luo J., Warnock G.L. Mesenchymal stem cells: prospects for cancer therapy. Emerging trends in cell and gene therapy 2013, 271-286. Humana Press, New York. M.K. Danquah, R.I. Mahato (Eds.).
31. Khakoo A.Y., Pati S., Anderson S.A., Reid W., Elshal M.F., Rovira I.I., et al. Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. JExp Med 2006, 203:1235-1247.