Polymorphisms in the human inhibitory signal-regulatory protein α do not affect binding to its ligand CD47

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 10024-10028

  Hatherley, Deborah ^a   Lea, Susan M ^a   Johnson, Steven ^a   Barclay, A Neil ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; DNA SEQUENCES; GENES; PROTEINS; X RAY CRYSTALLOGRAPHY;

AMINO ACID RESIDUES; LIGAND BINDING; LIGAND BINDING DOMAIN; MEMBRANE PROTEINS; MYELOID CELLS; NO BINDING; WEAK INTERACTIONS; XENOTRANSPLANTATION;

LIGANDS;

AMINO ACID; CD47 ANTIGEN; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN ALPHA; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTALLIZATION; HUMAN; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN POLYMORPHISM; X RAY CRYSTALLOGRAPHY;

CANCER THERAPY; CD47; CELL SURFACE RECEPTOR; IMMUNOLOGY; INHIBITORY RECEPTOR; LEUKOCYTE; MEMBRANE PROTEINS; PEPTIDE INTERACTIONS; PROTEIN STRUCTURE; SIRPΑ;

ALLELES; ANIMALS; ANTIGENS, CD47; ANTIGENS, DIFFERENTIATION; BINDING SITES; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; LIGANDS; PEPTIDES; POLYMORPHISM, GENETIC; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC;

EID: 84898072247     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.550558     Document Type: Article

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