Development of therapeutic microbubbles for enhancing ultrasound-mediated gene delivery

Journal of Controlled Release

Volumn 182, Issue 1, 2014, Pages 111-120

  Sun, Ryan R ^a   Noble, Misty L ^a   Sun, Samuel S ^a   Song, Shuxian ^a   Miao, Carol H ^a,b  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Acoustic cavitation; Microbubbles; Nonviral gene transfer; Ultrasound mediated gene delivery

Indexed keywords

CAVITATION; CELL MEMBRANES; CYTOLOGY; DNA; DRUG DELIVERY; GENE THERAPY;

ACOUSTIC CAVITATIONS; CELL MEMBRANE PERMEABILITY; CLINICAL APPLICATION; LOCALIZED DELIVERY; MICROBUBBLES; NONVIRAL GENE TRANSFER; TRANSGENE EXPRESSION; ULTRASOUND-MEDIATED GENE DELIVERY;

GENE TRANSFER;

CONTRAST MEDIUM; LUCIFERASE; PLASMID DNA; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DNA; FLUOROCARBON; GREEN FLUORESCENT PROTEIN; LIPID; PERFLUTREN;

ARTICLE; CELL STRAIN HEK293; CELL VIABILITY; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROBUBBLE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OXIDATION; PRIORITY JOURNAL; RAT; ULTRASOUND; ZETA POTENTIAL; ANIMAL; BLOOD; CHEMISTRY; DRUG EFFECTS; GENE TRANSFER; GENETICS; HEK293 CELL LINE; LIVER; MALE; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CONTRAST MEDIA; DNA; FLUOROCARBONS; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; LIPIDS; LIVER; MALE; MICROBUBBLES; RATS, SPRAGUE-DAWLEY; ULTRASONICS;

EID: 84898071442     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.03.002     Document Type: Article

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