Polymer nanoparticles for enhanced immune response: Combined delivery of tumor antigen and small interference RNA for immunosuppressive gene to dendritic cells

Acta Biomaterialia

Volumn 10, Issue 5, 2014, Pages 2169-2176

  Heo, Min Beom ^a   Cho, Mi Young ^a   Lim, Yong Taik ^b  

^a Chungnam National University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Antigen delivery; Cancer vaccine; Dendritic cells; Nanoparticles; SOCS1

Indexed keywords

ANTIGENS; CYTOLOGY; DISEASES; EFFICIENCY; EMULSIFICATION; ENCAPSULATION; GENE EXPRESSION; IMMUNE SYSTEM; NANOPARTICLES; RNA; T-CELLS; TUMORS;

ANTIGEN DELIVERY; BONE MARROW; CANCER VACCINE; DENDRITIC CELL; DENDRITICS; GLYCOLIC ACIDS; OVALBUMINS; POLY LACTIDE; SMALL INTERFERENCE RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1;

VACCINES;

INTERLEUKIN 12; INTERLEUKIN 6; NANOPARTICLE; OVALBUMIN; POLY(LACTIDE CO GLYCOLIC ACID)NANOPARTICLE; POLYGLACTIN; SMALL INTERFERING RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SOCS1 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; CROSS PRESENTATION; CYTOKINE RESPONSE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; ENCAPSULATION; FEMALE; GENE EXPRESSION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CHEMISTRY; CHICKEN; CYTOLOGY; ENDOCYTOSIS; GENE SILENCING; GENE TRANSFER; IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; PARTICLE SIZE; SYNTHESIS; ULTRASTRUCTURE;

ANIMALS; ANTIGENS, NEOPLASM; CD8-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CHICKENS; CYTOKINES; DENDRITIC CELLS; ENDOCYTOSIS; FEMALE; GENE SILENCING; GENE TRANSFER TECHNIQUES; IMMUNITY; IMMUNOSUPPRESSION; INFLAMMATION MEDIATORS; LACTIC ACID; MICE; MICE, INBRED C57BL; NANOPARTICLES; OVALBUMIN; PARTICLE SIZE; POLYGLYCOLIC ACID; RNA, SMALL INTERFERING; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84898058652     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.12.050     Document Type: Article

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