Simvastatin suppresses head and neck squamous cell carcinoma ex vivo and enhances the cytostatic effects of chemotherapeutics

Cancer Chemotherapy and Pharmacology

Volumn 73, Issue 4, 2014, Pages 827-837

  Stoehr, Matthaeus ^a   Mozet, Christian ^a   Boehm, Andreas ^a   Aigner, Achim ^a   Dietz, Andreas ^a   Wichmann, Gunnar ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Cisplatin; Docetaxel; FLAVINO assay; Head and neck squamous cell carcinoma (HNSCC); Statins

Indexed keywords

CISPLATIN; DOCETAXEL; SIMVASTATIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER INHIBITION; CANCER LOCALIZATION; CANCER STAGING; CELL COUNT; CELL PROLIFERATION; CELL STRAIN KB; CELL VIABILITY; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG POTENTIATION; EX VIVO STUDY; FEMALE; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; MALE; PRIORITY JOURNAL; TREATMENT DURATION;

ANTICHOLESTEREMIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; KB CELLS; MALE; NEOPLASM STAGING; RISK FACTORS; SIMVASTATIN; TAXOIDS;

EID: 84898057824     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-014-2412-1     Document Type: Article

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