Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 7, 2014, Pages 1975-1984

  Li, De Qiang ^a   Zhao, Jing ^a   Li, Shao Ping ^a   Zhang, Qing Wen ^a  

^a University of Macau   (Macao)

Author keywords

Column switching; Liquid chromatography; Restricted access material; Xanthine oxidase inhibitors

Indexed keywords

CHEMICAL DETECTION; COLUMN CHROMATOGRAPHY; FLAVONOIDS; LEAD COMPOUNDS; LIQUIDS; MIXTURES; PLANT EXTRACTS;

BIOACTIVE COMPOUNDS; COLUMN SWITCHING; COMPETITIVE BINDING; DIODE ARRAY DETECTION; INHIBITION ASSAYS; NON-SPECIFIC BINDING; RESTRICTED ACCESS MATERIALS; XANTHINE OXIDASE;

LIQUID CHROMATOGRAPHY;

OROXYLUM; OROXYLUM INDICUM;

ENZYME INHIBITOR; PLANT EXTRACT; XANTHINE OXIDASE;

ARTICLE; BIGNONIACEAE; BINDING COMPETITION; CHEMISTRY; DRUG ANTAGONISM; DRUG DEVELOPMENT; EQUIPMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; ONLINE SYSTEM; PLANT SEED; PROTEIN BINDING; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

BIGNONIACEAE; BINDING, COMPETITIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DISCOVERY; ENZYME INHIBITORS; ONLINE SYSTEMS; PLANT EXTRACTS; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS; SEEDS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; XANTHINE OXIDASE;

EID: 84898042432     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-7612-8     Document Type: Article

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